Goserelin (acetate)_C-33 A Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Goserelin (acetate) perturbation in C-33 A cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Goserelin (acetate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.148473
ZNF608 zinc finger protein 608 0.129191
RPS6 ribosomal protein S6 0.116995
DST dystonin 0.107329
RPS3 ribosomal protein S3 0.102194
CENPF centromere protein F, 350/400kDa 0.082817
RPS8 ribosomal protein S8 0.0781583
RPS12 ribosomal protein S12 0.0779215
JMJD1C jumonji domain containing 1C 0.0739173
STAT1 signal transducer and activator of transcription 1, 91kDa 0.073189
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0721529
NEBL nebulette 0.0714959
ATP11A ATPase, class VI, type 11A 0.0686801
COL5A2 collagen, type V, alpha 2 0.0685263
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0655697
PDE4D phosphodiesterase 4D, cAMP-specific 0.0650259
RPS2 ribosomal protein S2 0.0640972
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0630027
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0626784
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0624379
HSPA8 heat shock 70kDa protein 8 0.0602326
KTN1 kinectin 1 (kinesin receptor) 0.0578929
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0558318
ASPH aspartate beta-hydroxylase 0.0556887
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0523967
RPS4X ribosomal protein S4, X-linked 0.0520531
RPL37A ribosomal protein L37a 0.0518642
SET SET nuclear proto-oncogene 0.0516937
MKI67 marker of proliferation Ki-67 0.0511247
DSCAM Down syndrome cell adhesion molecule 0.0492734
VCL vinculin 0.0487452
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0485864
SMC1A structural maintenance of chromosomes 1A 0.0478409
GYS1 glycogen synthase 1 (muscle) 0.046857
VMP1 vacuole membrane protein 1 0.0465363
PTMA prothymosin, alpha 0.0461899
ANKRD12 ankyrin repeat domain 12 0.045657
NFIA nuclear factor I/A 0.0456259
ATG10 autophagy related 10 0.0455818
APLP2 amyloid beta (A4) precursor-like protein 2 0.044124
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0429786
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0422626
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.0419747
ANKRD36 ankyrin repeat domain 36 0.0419277
PABPN1 poly(A) binding protein, nuclear 1 0.0412798
GOLGB1 golgin B1 0.0411554
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0408644
PNN pinin, desmosome associated protein 0.0405463
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0398477
RPL11 ribosomal protein L11 0.0394787
RPS21 ribosomal protein S21 0.03938
RPL26 ribosomal protein L26 0.039215
BRD2 bromodomain containing 2 0.038777
AKAP12 A kinase (PRKA) anchor protein 12 0.0380203
RPL13A ribosomal protein L13a 0.0379876
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.0376801
PRRC2C proline-rich coiled-coil 2C 0.0368723
PCM1 pericentriolar material 1 0.0367377
KIF5B kinesin family member 5B 0.0357279
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.035524
NGLY1 N-glycanase 1 0.0355011
SMYD3 SET and MYND domain containing 3 0.035497
RACK1 receptor for activated C kinase 1 0.0343777
RBBP6 retinoblastoma binding protein 6 0.0340813
PHF21A PHD finger protein 21A 0.0332593
RERE arginine-glutamic acid dipeptide (RE) repeats 0.03274
NALF1 NALCN channel auxiliary factor 1 0.0326166
USP47 ubiquitin specific peptidase 47 0.0325002
OGA O-GlcNAcase 0.0322694
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0322418
EEF1G eukaryotic translation elongation factor 1 gamma 0.0319645
KMT2C lysine (K)-specific methyltransferase 2C 0.0312886
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0311089
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0310301
NKTR natural killer cell triggering receptor 0.0310257
RPS17 ribosomal protein S17 0.0309631
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0308004
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0307396
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0304716
TRIP12 thyroid hormone receptor interactor 12 0.0304566
RPL34 ribosomal protein L34 0.0302257
BPTF bromodomain PHD finger transcription factor 0.0298254
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.0298073
FBXL7 F-box and leucine-rich repeat protein 7 0.0296264
ZC3H12B zinc finger CCCH-type containing 12B 0.0295946
CTNND1 catenin (cadherin-associated protein), delta 1 0.0292836
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0291647
HMGB2 high mobility group box 2 0.0291625
RPL23 ribosomal protein L23 0.0291061
BABAM2 BRISC and BRCA1 A complex member 2 0.028821
CCDC88A coiled-coil domain containing 88A 0.0287488
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0284983
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0283851
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.0280271
GOLGA4 golgin A4 0.0275117
PCBP2 poly(rC) binding protein 2 0.0273153
RSRC2 arginine/serine-rich coiled-coil 2 0.0272872
SRRM1 serine/arginine repetitive matrix 1 0.0270765
CEP250 centrosomal protein 250kDa 0.0268837
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.0268124

decreased expression

Symbol Name Standardized Value
NPAS3 neuronal PAS domain protein 3 -0.102235
SLIT2 slit homolog 2 (Drosophila) -0.101698
CTNNA3 catenin (cadherin-associated protein), alpha 3 -0.0987706
RAD51B RAD51 paralog B -0.0983399
CTNNA2 catenin (cadherin-associated protein), alpha 2 -0.0840986
CADM2 cell adhesion molecule 2 -0.0796489
HMGA1 high mobility group AT-hook 1 -0.048315
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0468251
ACACA acetyl-CoA carboxylase alpha -0.0448002
LRPPRC leucine-rich pentatricopeptide repeat containing -0.0446743
SHROOM3 shroom family member 3 -0.0433353
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0430783
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.040904
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0404153
VDAC1 voltage-dependent anion channel 1 -0.0386877
NUP58 nucleoporin 58 -0.0380517
WDR45B WD repeat domain 45B -0.0377201
TMEM123 transmembrane protein 123 -0.0354627
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0344287
GAB2 GRB2-associated binding protein 2 -0.0317333
RAP1B RAP1B, member of RAS oncogene family -0.031536
MCTP1 multiple C2 domains, transmembrane 1 -0.0312331
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0304455
LIMS1 LIM and senescent cell antigen-like domains 1 -0.0298875
TUBB tubulin, beta class I -0.0296822
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -0.0292268
CELF2 CUGBP, Elav-like family member 2 -0.0287278
EEF2 eukaryotic translation elongation factor 2 -0.0285176
LMAN1 lectin, mannose-binding, 1 -0.0276795
FOXO3 forkhead box O3 -0.0263255
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.0258067
RLF rearranged L-myc fusion -0.0252165
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.0249771
ADGRG6 adhesion G protein-coupled receptor G6 -0.0248072
NPR2 natriuretic peptide receptor 2 -0.0237716
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -0.0236767
PTPRG protein tyrosine phosphatase, receptor type, G -0.0236587
NR5A2 nuclear receptor subfamily 5, group A, member 2 -0.0236471
NF1 neurofibromin 1 -0.0236397
NT5C2 5'-nucleotidase, cytosolic II -0.0234867
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0231799
HMGB1 high mobility group box 1 -0.0224164
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -0.0221665
ARHGAP32 Rho GTPase activating protein 32 -0.0221282
BSG basigin (Ok blood group) -0.0220878
CDC73 cell division cycle 73 -0.0220814
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.0220636
EIF4A1 eukaryotic translation initiation factor 4A1 -0.0219619
BRWD1 bromodomain and WD repeat domain containing 1 -0.0219006
TENM3 teneurin transmembrane protein 3 -0.0218932
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0217457
KDM3A lysine (K)-specific demethylase 3A -0.0214587
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.0213089
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -0.0212979
KPNB1 karyopherin (importin) beta 1 -0.0212069
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.0211996
TRIO trio Rho guanine nucleotide exchange factor -0.0211434
RPS24 ribosomal protein S24 -0.0210673
EMP1 epithelial membrane protein 1 -0.0207566
USP3 ubiquitin specific peptidase 3 -0.0205649
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0204926
SALL4 spalt-like transcription factor 4 -0.0203427
EFNA5 ephrin-A5 -0.0198818
NRF1 nuclear respiratory factor 1 -0.0198808
R3HDM1 R3H domain containing 1 -0.0197194
CDH18 cadherin 18, type 2 -0.0188123
PNPT1 polyribonucleotide nucleotidyltransferase 1 -0.0184814
SERBP1 SERPINE1 mRNA binding protein 1 -0.0184496
E2F3 E2F transcription factor 3 -0.0182364
SREBF2 sterol regulatory element binding transcription factor 2 -0.0178657
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.0178295
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0176983
FBL fibrillarin -0.0173271
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0172486
ABI2 abl-interactor 2 -0.0171767
PARD3 par-3 family cell polarity regulator -0.0170905
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0170144
RPL27A ribosomal protein L27a -0.016986
ACTG1 actin gamma 1 -0.0169674
NR4A3 nuclear receptor subfamily 4, group A, member 3 -0.0168588
SSBP2 single-stranded DNA binding protein 2 -0.0165839
BLTP2 bridge-like lipid transfer protein family member 2 -0.0164517
ATRN attractin -0.0164054
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.0163032
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.0162172
RPLP1 ribosomal protein, large, P1 -0.0161686
CAMKMT calmodulin-lysine N-methyltransferase -0.0160762
BICD1 bicaudal D homolog 1 (Drosophila) -0.0160174
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 -0.015947
RPS20 ribosomal protein S20 -0.0158856
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) -0.0158008
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.0157129
SLF1 SMC5-SMC6 complex localization factor 1 -0.0155848
TMEM117 transmembrane protein 117 -0.0155504
ZNF217 zinc finger protein 217 -0.0154811
PDIA3 protein disulfide isomerase family A, member 3 -0.0153752
ARF1 ADP-ribosylation factor 1 -0.0152973
NAMPT nicotinamide phosphoribosyltransferase -0.0152529
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -0.0151746
XPO1 exportin 1 -0.0151152