| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.129091 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.115052 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0910333 |
| FMN1 | formin 1 | 0.075649 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0750629 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0750464 |
| ASPH | aspartate beta-hydroxylase | 0.0739971 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0717688 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0666133 |
| SETBP1 | SET binding protein 1 | 0.0636617 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0625749 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0562744 |
| ZYX | zyxin | 0.0562089 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0559473 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0554189 |
| TPR | translocated promoter region, nuclear basket protein | 0.0541006 |
| SFTPA2 | surfactant protein A2 | 0.0532755 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0532273 |
| FMNL2 | formin-like 2 | 0.0495172 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0486504 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0475584 |
| VCL | vinculin | 0.047492 |
| MT2A | metallothionein 2A | 0.0459856 |
| ACTN1 | actinin, alpha 1 | 0.0445843 |
| GPC6 | glypican 6 | 0.0438097 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0430714 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0422558 |
| MSN | moesin | 0.0407507 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0391623 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0389682 |
| GOLGB1 | golgin B1 | 0.0388611 |
| VMP1 | vacuole membrane protein 1 | 0.0377606 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0377217 |
| DST | dystonin | 0.0374469 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0369112 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0368021 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0366659 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0365837 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0364522 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0364488 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0356403 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0355506 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0346723 |
| TMF1 | TATA element modulatory factor 1 | 0.0345896 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0345521 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.034247 |
| SDC2 | syndecan 2 | 0.0339793 |
| FLNB | filamin B, beta | 0.0335575 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0333706 |
| CENPF | centromere protein F, 350/400kDa | 0.0333669 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0329161 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0324163 |
| AFDN | afadin, adherens junction formation factor | 0.032266 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0319592 |
| TLE4 | transducin-like enhancer of split 4 | 0.0317457 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0313536 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0313187 |
| BRD2 | bromodomain containing 2 | 0.0300409 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0298762 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0293134 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0292151 |
| MCL1 | myeloid cell leukemia 1 | 0.0288834 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0286356 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0286336 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0285171 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0282221 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0281388 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0279266 |
| PRELID2 | PRELI domain containing 2 | 0.027694 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.027589 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0275223 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0274104 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0273112 |
| JUN | jun proto-oncogene | 0.0272496 |
| EGR1 | early growth response 1 | 0.0270675 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0264341 |
| SEPTIN9 | septin 9 | 0.026256 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0258747 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0258651 |
| RTN4 | reticulon 4 | 0.0258639 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0258605 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0258464 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0255154 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0253392 |
| CALU | calumenin | 0.0252944 |
| RCAN1 | regulator of calcineurin 1 | 0.0249782 |
| SLK | STE20-like kinase | 0.0246536 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0243923 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0241404 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0238855 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0238098 |
| WASL | Wiskott-Aldrich syndrome-like | 0.023803 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0237847 |
| PARVB | parvin, beta | 0.0235497 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.023542 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0235267 |
| JMJD1C | jumonji domain containing 1C | 0.0229911 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0226491 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0226445 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0223782 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.271966 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108642 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.10046 |
| FN1 | fibronectin 1 | -0.0847594 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0837873 |
| DCT | dopachrome tautomerase | -0.0822943 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0715696 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0688988 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0657811 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0643792 |
| TMEM123 | transmembrane protein 123 | -0.0628658 |
| NLGN1 | neuroligin 1 | -0.059681 |
| GDF15 | growth differentiation factor 15 | -0.0521831 |
| NAV3 | neuron navigator 3 | -0.0513106 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0467361 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0464151 |
| HMCN1 | hemicentin 1 | -0.0440266 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0438145 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0429108 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0424278 |
| VIM | vimentin | -0.0405573 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0395935 |
| CDK14 | cyclin-dependent kinase 14 | -0.0387589 |
| PGK1 | phosphoglycerate kinase 1 | -0.0381305 |
| PKM | pyruvate kinase, muscle | -0.0377643 |
| CDC73 | cell division cycle 73 | -0.0352402 |
| RFX7 | regulatory factor X, 7 | -0.0348127 |
| RNF24 | ring finger protein 24 | -0.0344488 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0337979 |
| MACROD2 | MACRO domain containing 2 | -0.032412 |
| TRIM2 | tripartite motif containing 2 | -0.0320963 |
| NDRG1 | N-myc downstream regulated 1 | -0.0320959 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0311869 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0303059 |
| GNAS | GNAS complex locus | -0.0299755 |
| VGF | VGF nerve growth factor inducible | -0.0298765 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0297222 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0296656 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0293602 |
| SCFD2 | sec1 family domain containing 2 | -0.0292419 |
| EHBP1 | EH domain binding protein 1 | -0.0288107 |
| PDE10A | phosphodiesterase 10A | -0.0279136 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0279124 |
| CTSD | cathepsin D | -0.0275336 |
| NRCAM | neuronal cell adhesion molecule | -0.0273624 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0271525 |
| NBAS | neuroblastoma amplified sequence | -0.0271506 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271298 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0271106 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0269445 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.026567 |
| RNF145 | ring finger protein 145 | -0.0264299 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0264004 |
| INSIG1 | insulin induced gene 1 | -0.0262591 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0260581 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0259013 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.025877 |
| S100A6 | S100 calcium binding protein A6 | -0.0250061 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0249426 |
| TMSB10 | thymosin beta 10 | -0.0249183 |
| A2M | alpha-2-macroglobulin | -0.0245591 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0242912 |
| WDR45B | WD repeat domain 45B | -0.0241268 |
| PHF21A | PHD finger protein 21A | -0.0238761 |
| NUP58 | nucleoporin 58 | -0.0236672 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0234223 |
| IER3 | immediate early response 3 | -0.0230602 |
| GHR | growth hormone receptor | -0.0230526 |
| FHIT | fragile histidine triad | -0.0230475 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0229372 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.022857 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0227986 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0226143 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.02259 |
| ZNF292 | zinc finger protein 292 | -0.0222051 |
| SSH1 | slingshot protein phosphatase 1 | -0.0218473 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0217 |
| MEIS2 | Meis homeobox 2 | -0.0214668 |
| COL1A2 | collagen, type I, alpha 2 | -0.0214064 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0212053 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0211775 |
| NHSL1 | NHS-like 1 | -0.0210065 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.0209933 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0207782 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0207303 |
| ZNF704 | zinc finger protein 704 | -0.0207156 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0207113 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.0205763 |
| BNC2 | basonuclin 2 | -0.0204805 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0204517 |
| LNPK | lunapark, ER junction formation factor | -0.0202373 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0199362 |
| RHEB | Ras homolog enriched in brain | -0.0198195 |
| CD109 | CD109 molecule | -0.0197152 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.019621 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0195995 |
| LSAMP | limbic system-associated membrane protein | -0.0195352 |
| BSG | basigin (Ok blood group) | -0.0193154 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.019027 |
| CFAP20DC | CFAP20 domain containing | -0.0189297 |
