| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.144077 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.136646 |
| FNDC3B | fibronectin type III domain containing 3B | 0.131617 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0978528 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0815821 |
| MT2A | metallothionein 2A | 0.0797967 |
| APOL1 | apolipoprotein L, 1 | 0.0779073 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0745649 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0720181 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0686345 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0647915 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0638321 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0611723 |
| FAM107B | family with sequence similarity 107, member B | 0.0610602 |
| SMAD3 | SMAD family member 3 | 0.0610425 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.057315 |
| FAM3C | family with sequence similarity 3, member C | 0.0550276 |
| TGM2 | transglutaminase 2 | 0.0547666 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0522113 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.051836 |
| TAPBP | TAP binding protein (tapasin) | 0.050898 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0501859 |
| BRD2 | bromodomain containing 2 | 0.0499467 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0485462 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0467848 |
| APP | amyloid beta (A4) precursor protein | 0.0446707 |
| GOLGB1 | golgin B1 | 0.0444872 |
| B2M | beta-2-microglobulin | 0.0442544 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0442181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0437729 |
| SGMS2 | sphingomyelin synthase 2 | 0.0430836 |
| BARX2 | BARX homeobox 2 | 0.0428152 |
| SFTPA2 | surfactant protein A2 | 0.0426576 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0417023 |
| RPS3 | ribosomal protein S3 | 0.0412588 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0398734 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0386791 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0374762 |
| ARRDC3 | arrestin domain containing 3 | 0.036815 |
| EFNA5 | ephrin-A5 | 0.0364787 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0361253 |
| VMP1 | vacuole membrane protein 1 | 0.0345939 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.034498 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0343775 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0337434 |
| PCBP2 | poly(rC) binding protein 2 | 0.0335196 |
| HSPA8 | heat shock 70kDa protein 8 | 0.032104 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.031095 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0310737 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0309018 |
| ANO6 | anoctamin 6 | 0.0307058 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0306401 |
| PDZD8 | PDZ domain containing 8 | 0.0306247 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0303929 |
| JAK1 | Janus kinase 1 | 0.0301716 |
| EZR | ezrin | 0.0296907 |
| PNN | pinin, desmosome associated protein | 0.0290322 |
| AHNAK | AHNAK nucleoprotein | 0.0289648 |
| DSPP | dentin sialophosphoprotein | 0.0289001 |
| OPTN | optineurin | 0.0287645 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0285701 |
| TXNIP | thioredoxin interacting protein | 0.0285102 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0283081 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0278061 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0277804 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.027271 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0268517 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0264335 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0263997 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0257019 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.025693 |
| SEPTIN9 | septin 9 | 0.025465 |
| AREG | amphiregulin | 0.0254276 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0253796 |
| TOP1 | topoisomerase (DNA) I | 0.0248693 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0248607 |
| HOMER2 | homer scaffolding protein 2 | 0.0247803 |
| ATF3 | activating transcription factor 3 | 0.0247432 |
| SERINC1 | serine incorporator 1 | 0.0247278 |
| TMEM51 | transmembrane protein 51 | 0.0247156 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0244777 |
| FAM13A | family with sequence similarity 13, member A | 0.024334 |
| SLTM | SAFB-like, transcription modulator | 0.0239565 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0237274 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0237165 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0236858 |
| SDC4 | syndecan 4 | 0.0236534 |
| KIAA1217 | KIAA1217 | 0.0236253 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0236167 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0233241 |
| RPS6 | ribosomal protein S6 | 0.0233148 |
| CFB | complement factor B | 0.0232964 |
| DST | dystonin | 0.0231752 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0230767 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.022985 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.022956 |
| NOTCH2 | notch 2 | 0.0229462 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0226854 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0226072 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0225952 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP7 | matrix metallopeptidase 7 | -0.173451 |
| TMSB10 | thymosin beta 10 | -0.140101 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.132538 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.125394 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.115642 |
| S100A6 | S100 calcium binding protein A6 | -0.097821 |
| HLA-B | major histocompatibility complex, class I, B | -0.0852778 |
| ACTG1 | actin gamma 1 | -0.0836998 |
| CP | ceruloplasmin (ferroxidase) | -0.0795241 |
| HMGA1 | high mobility group AT-hook 1 | -0.0771411 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0658523 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0652157 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0640435 |
| ANXA2 | annexin A2 | -0.0640061 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0617741 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0600419 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0589932 |
| GNAS | GNAS complex locus | -0.0585059 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.058492 |
| MUC4 | mucin 4, cell surface associated | -0.0564566 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0563519 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0554758 |
| HLA-A | major histocompatibility complex, class I, A | -0.0539662 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0516674 |
| PGK1 | phosphoglycerate kinase 1 | -0.0515006 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0512167 |
| NCKAP5 | NCK-associated protein 5 | -0.0508435 |
| PTMA | prothymosin, alpha | -0.0503799 |
| TPM4 | tropomyosin 4 | -0.0500678 |
| PKM | pyruvate kinase, muscle | -0.0496109 |
| PLAU | plasminogen activator, urokinase | -0.0479019 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0466318 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0460657 |
| EHBP1 | EH domain binding protein 1 | -0.0460525 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0459631 |
| PLAT | plasminogen activator, tissue | -0.0458406 |
| DTNA | dystrobrevin, alpha | -0.0456821 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0455847 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0446612 |
| PARD3 | par-3 family cell polarity regulator | -0.0445369 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0439307 |
| VIM | vimentin | -0.0432491 |
| RRBP1 | ribosome binding protein 1 | -0.0432039 |
| LASP1 | LIM and SH3 protein 1 | -0.0424055 |
| PRKCA | protein kinase C, alpha | -0.0421262 |
| RCOR1 | REST corepressor 1 | -0.04187 |
| IER3 | immediate early response 3 | -0.0408981 |
| MEF2A | myocyte enhancer factor 2A | -0.0397385 |
| MCU | mitochondrial calcium uniporter | -0.0390302 |
| INSIG1 | insulin induced gene 1 | -0.0389883 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0388469 |
| RASAL2 | RAS protein activator like 2 | -0.0387755 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0378052 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0378028 |
| VCL | vinculin | -0.0376493 |
| S100A10 | S100 calcium binding protein A10 | -0.0375308 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0373347 |
| ITGB4 | integrin, beta 4 | -0.0372969 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0370453 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0367624 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0365736 |
| JUP | junction plakoglobin | -0.0361987 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0361353 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0360665 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0349849 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0348305 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0347364 |
| TMEM165 | transmembrane protein 165 | -0.0342721 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0331659 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0323494 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.032008 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0315425 |
| TMEM123 | transmembrane protein 123 | -0.0314649 |
| PCDH7 | protocadherin 7 | -0.031346 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0304685 |
| SPAG9 | sperm associated antigen 9 | -0.0304624 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0302607 |
| NRG1 | neuregulin 1 | -0.0301493 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0300341 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0298721 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0298303 |
| TMSB4X | thymosin beta 4, X-linked | -0.0298303 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0297838 |
| ACTN4 | actinin, alpha 4 | -0.0293245 |
| LAMB3 | laminin, beta 3 | -0.0291176 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0288189 |
| POTEF | POTE ankyrin domain family, member F | -0.028059 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0277973 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0277849 |
| FBXO11 | F-box protein 11 | -0.0274741 |
| FLNB | filamin B, beta | -0.0273611 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0273091 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0270471 |
| ARF1 | ADP-ribosylation factor 1 | -0.0269757 |
| ERBIN | erbb2 interacting protein | -0.0268132 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0267849 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0266844 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0266668 |
| NDRG1 | N-myc downstream regulated 1 | -0.026615 |
| TJP1 | tight junction protein 1 | -0.0263139 |
