| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.265423 |
| SMAD3 | SMAD family member 3 | 0.111141 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0688182 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0667966 |
| EFNB2 | ephrin-B2 | 0.0659516 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0649014 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0631547 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0605977 |
| AREG | amphiregulin | 0.0601307 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0593627 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0552234 |
| DST | dystonin | 0.0507551 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0477621 |
| STK24 | serine/threonine kinase 24 | 0.0464452 |
| IFNGR1 | interferon gamma receptor 1 | 0.0462367 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0456647 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0455224 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0449597 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0427162 |
| ASPH | aspartate beta-hydroxylase | 0.0421862 |
| VMP1 | vacuole membrane protein 1 | 0.041997 |
| YAP1 | Yes-associated protein 1 | 0.0419204 |
| BCL2L1 | BCL2-like 1 | 0.041128 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0409384 |
| MYO1E | myosin IE | 0.0396868 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0367404 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0360596 |
| DSPP | dentin sialophosphoprotein | 0.035876 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0355424 |
| TJP1 | tight junction protein 1 | 0.0338919 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0331363 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0323356 |
| VCL | vinculin | 0.0319713 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0316421 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0308158 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.030738 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0302503 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.030052 |
| SLK | STE20-like kinase | 0.0300196 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0299521 |
| MYO5B | myosin VB | 0.0299103 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0290942 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0290181 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0287704 |
| PRSS22 | protease, serine, 22 | 0.0283194 |
| RBM26 | RNA binding motif protein 26 | 0.0279173 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.027812 |
| DUSP16 | dual specificity phosphatase 16 | 0.027761 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0272318 |
| RPS3 | ribosomal protein S3 | 0.0271375 |
| PDZD8 | PDZ domain containing 8 | 0.0266606 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0263972 |
| CUL3 | cullin 3 | 0.0263412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0258352 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0252131 |
| LAMB3 | laminin, beta 3 | 0.0251874 |
| ETV6 | ets variant 6 | 0.0251702 |
| KYNU | kynureninase | 0.0247595 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0240616 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0240222 |
| TXNRD1 | thioredoxin reductase 1 | 0.0239548 |
| DIAPH1 | diaphanous-related formin 1 | 0.0239149 |
| EFNA5 | ephrin-A5 | 0.0237362 |
| MLPH | melanophilin | 0.0232638 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0230246 |
| FAT1 | FAT atypical cadherin 1 | 0.0229829 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0228312 |
| GOLGB1 | golgin B1 | 0.0224376 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0222732 |
| HKDC1 | hexokinase domain containing 1 | 0.0222409 |
| PRELID2 | PRELI domain containing 2 | 0.0221488 |
| SEPTIN9 | septin 9 | 0.0221265 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0220823 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219704 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0214881 |
| SMYD3 | SET and MYND domain containing 3 | 0.0214858 |
| YBX3 | Y box binding protein 3 | 0.0214727 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | 0.0213896 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0212817 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0209169 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0207072 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0206516 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0206255 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0205701 |
| TOX3 | TOX high mobility group box family member 3 | 0.0205402 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0205286 |
| RND3 | Rho family GTPase 3 | 0.0205244 |
| WWOX | WW domain containing oxidoreductase | 0.0205226 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0205182 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0205096 |
| LRRC1 | leucine rich repeat containing 1 | 0.0202856 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0199917 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0199575 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0197939 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0197392 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0196947 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0195716 |
| CORO1C | coronin, actin binding protein, 1C | 0.0195206 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194804 |
| TPR | translocated promoter region, nuclear basket protein | 0.0194728 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.119868 |
| LYZ | lysozyme | -0.116529 |
| EGR1 | early growth response 1 | -0.101883 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0963505 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0893055 |
| PKM | pyruvate kinase, muscle | -0.0800638 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0791181 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0766413 |
| HLA-B | major histocompatibility complex, class I, B | -0.0753447 |
| TXNIP | thioredoxin interacting protein | -0.0750127 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0704273 |
| NPSR1 | neuropeptide S receptor 1 | -0.0691075 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0658229 |
| NDRG1 | N-myc downstream regulated 1 | -0.0636733 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0635391 |
| INTS6 | integrator complex subunit 6 | -0.0629733 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0624531 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0610532 |
| MUC20 | mucin 20, cell surface associated | -0.0607859 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0607515 |
| HLA-E | major histocompatibility complex, class I, E | -0.0585607 |
| RIGI | RNA sensor RIG-I | -0.0571229 |
| RNF213 | ring finger protein 213 | -0.0566245 |
| MX1 | MX dynamin-like GTPase 1 | -0.0557379 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0555146 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0553085 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0545619 |
| PLSCR2 | phospholipid scramblase 2 | -0.0534288 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0531037 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0523977 |
| AHI1 | Abelson helper integration site 1 | -0.0501699 |
| SQSTM1 | sequestosome 1 | -0.0493806 |
| HLA-C | major histocompatibility complex, class I, C | -0.0491797 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0491048 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0485092 |
| PRKCA | protein kinase C, alpha | -0.0478685 |
| PLSCR1 | phospholipid scramblase 1 | -0.0462886 |
| LOC112694756 | uncharaterized LOC112694756 | -0.046233 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0460723 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0460221 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0459103 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0456267 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0436422 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0428074 |
| UBC | ubiquitin C | -0.0422026 |
| PERP | PERP, TP53 apoptosis effector | -0.0411266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0409273 |
| WDR45B | WD repeat domain 45B | -0.0398511 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0397651 |
| XAF1 | XIAP associated factor 1 | -0.0386353 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0375529 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0373911 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0371303 |
| VDAC1 | voltage-dependent anion channel 1 | -0.036308 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0360289 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0358156 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0357815 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0356849 |
| SP100 | SP100 nuclear antigen | -0.0356795 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0352377 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0352357 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0347878 |
| S100A6 | S100 calcium binding protein A6 | -0.0344943 |
| IRF1 | interferon regulatory factor 1 | -0.0342193 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0340557 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0334803 |
| ARF1 | ADP-ribosylation factor 1 | -0.0329461 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0325334 |
| ANXA2 | annexin A2 | -0.0319416 |
| MXD1 | MAX dimerization protein 1 | -0.0317677 |
| ZNF609 | zinc finger protein 609 | -0.0315182 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0313055 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0309222 |
| CMIP | c-Maf inducing protein | -0.0306231 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0305921 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0301889 |
| SERINC5 | serine incorporator 5 | -0.0300542 |
| TNS4 | tensin 4 | -0.029653 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0295529 |
| MORF4L2 | mortality factor 4 like 2 | -0.0295265 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0295093 |
| HLA-A | major histocompatibility complex, class I, A | -0.029489 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0294111 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0292138 |
| B2M | beta-2-microglobulin | -0.0290083 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0284029 |
| ABLIM1 | actin binding LIM protein 1 | -0.0283574 |
| H1-0 | H1.0 linker histone | -0.0282303 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0281874 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0280482 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0280282 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0278284 |
| FDPS | farnesyl diphosphate synthase | -0.027703 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0276097 |
| TFRC | transferrin receptor | -0.0274495 |
| SSH2 | slingshot protein phosphatase 2 | -0.0269746 |
| WASF2 | WAS protein family, member 2 | -0.0269204 |
| NF1 | neurofibromin 1 | -0.026748 |
| CTSD | cathepsin D | -0.0266845 |
| RPLP1 | ribosomal protein, large, P1 | -0.0265043 |
