| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.12905 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0570977 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0529827 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0513066 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0510621 |
| AHNAK | AHNAK nucleoprotein | 0.0419061 |
| EZR | ezrin | 0.0410348 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0407246 |
| GOLGB1 | golgin B1 | 0.0366016 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0364651 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0364259 |
| TMF1 | TATA element modulatory factor 1 | 0.0363637 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0359751 |
| MT2A | metallothionein 2A | 0.0354662 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0343874 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.034118 |
| FTL | ferritin, light polypeptide | 0.0341007 |
| PRELID2 | PRELI domain containing 2 | 0.0320201 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0316451 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0309625 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0297969 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0290262 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0279924 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.026656 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0265378 |
| TJP1 | tight junction protein 1 | 0.0256174 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0251781 |
| DSPP | dentin sialophosphoprotein | 0.0248689 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0238781 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0237087 |
| HELZ | helicase with zinc finger | 0.0235441 |
| ZNF638 | zinc finger protein 638 | 0.0234657 |
| FNIP1 | folliculin interacting protein 1 | 0.0232985 |
| MACROD2 | MACRO domain containing 2 | 0.0224911 |
| DSCAM | Down syndrome cell adhesion molecule | 0.022473 |
| TXNIP | thioredoxin interacting protein | 0.0224 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0216846 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0214101 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0212705 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0211917 |
| WWC2 | WW and C2 domain containing 2 | 0.0206853 |
| TAPBP | TAP binding protein (tapasin) | 0.0203224 |
| YEATS2 | YEATS domain containing 2 | 0.0201765 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0201338 |
| HDLBP | high density lipoprotein binding protein | 0.0200014 |
| SEPTIN9 | septin 9 | 0.0197419 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0197174 |
| ARRDC3 | arrestin domain containing 3 | 0.0197116 |
| RNF24 | ring finger protein 24 | 0.0197002 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0193236 |
| ZNF292 | zinc finger protein 292 | 0.0189192 |
| TPM3 | tropomyosin 3 | 0.0187081 |
| YBX3 | Y box binding protein 3 | 0.0187026 |
| NEBL | nebulette | 0.0186498 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0186436 |
| CD47 | CD47 molecule | 0.0184895 |
| OGA | O-GlcNAcase | 0.0182696 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0179745 |
| RIOK3 | RIO kinase 3 | 0.017582 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0175154 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0170104 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0169951 |
| SERINC1 | serine incorporator 1 | 0.0168824 |
| JUN | jun proto-oncogene | 0.016824 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0168232 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0167655 |
| RPS2 | ribosomal protein S2 | 0.0166701 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0165474 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0163811 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0162385 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0159517 |
| CORO1C | coronin, actin binding protein, 1C | 0.0157718 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0154972 |
| FAM13B | family with sequence similarity 13, member B | 0.0154898 |
| MATR3 | matrin 3 | 0.0152895 |
| CDC73 | cell division cycle 73 | 0.0151969 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0147669 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.014514 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.0144854 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0143095 |
| ANXA2 | annexin A2 | 0.0142482 |
| H1-4 | H1.4 linker histone, cluster member | 0.0139962 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0139725 |
| EXOC6B | exocyst complex component 6B | 0.0139279 |
| AFDN | afadin, adherens junction formation factor | 0.0139041 |
| CEP250 | centrosomal protein 250kDa | 0.0138143 |
| CDCP1 | CUB domain containing protein 1 | 0.0137497 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0137341 |
| LDHA | lactate dehydrogenase A | 0.0136866 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0136825 |
| CLU | clusterin | 0.0136419 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0136228 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0135474 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.013463 |
| BRD2 | bromodomain containing 2 | 0.0134451 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0133594 |
| TLK1 | tousled-like kinase 1 | 0.0133307 |
| H1-2 | H1.2 linker histone, cluster member | 0.0133198 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0132978 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0132686 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.335121 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.143745 |
| FAT1 | FAT atypical cadherin 1 | -0.122676 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.113803 |
| TMSB10 | thymosin beta 10 | -0.112417 |
| PKM | pyruvate kinase, muscle | -0.0776937 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.072178 |
| RPL35A | ribosomal protein L35a | -0.070453 |
| RPS24 | ribosomal protein S24 | -0.0698857 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0660526 |
| RPS8 | ribosomal protein S8 | -0.0645511 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0601085 |
| RPLP1 | ribosomal protein, large, P1 | -0.0600188 |
| RAD51B | RAD51 paralog B | -0.0599729 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0577075 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.05672 |
| RPS13 | ribosomal protein S13 | -0.0524335 |
| ACTG1 | actin gamma 1 | -0.0521569 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0517985 |
| ENO1 | enolase 1, (alpha) | -0.0513476 |
| RPLP2 | ribosomal protein, large, P2 | -0.0497886 |
| LDHB | lactate dehydrogenase B | -0.0485114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0474276 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0472644 |
| CCND1 | cyclin D1 | -0.0468394 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0453841 |
| SERINC5 | serine incorporator 5 | -0.0451746 |
| MKI67 | marker of proliferation Ki-67 | -0.0450671 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0445749 |
| GNAS | GNAS complex locus | -0.0434746 |
| RPS25 | ribosomal protein S25 | -0.0416722 |
| CADPS | Ca++-dependent secretion activator | -0.0414061 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0409524 |
| TUBA1B | tubulin, alpha 1b | -0.0401472 |
| RPS6 | ribosomal protein S6 | -0.0400178 |
| HMGB1 | high mobility group box 1 | -0.0388589 |
| HMGA2 | high mobility group AT-hook 2 | -0.0384081 |
| EGR1 | early growth response 1 | -0.037763 |
| S100A6 | S100 calcium binding protein A6 | -0.0376633 |
| S100A9 | S100 calcium binding protein A9 | -0.0376089 |
| RPL23 | ribosomal protein L23 | -0.0376075 |
| RPL34 | ribosomal protein L34 | -0.0367138 |
| FHIT | fragile histidine triad | -0.0365429 |
| KRT18 | keratin 18, type I | -0.03582 |
| ZNRF3 | zinc and ring finger 3 | -0.0358078 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0353791 |
| RPL7A | ribosomal protein L7a | -0.0353542 |
| PERP | PERP, TP53 apoptosis effector | -0.0350129 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.034994 |
| POTEF | POTE ankyrin domain family, member F | -0.0343662 |
| MSI2 | musashi RNA-binding protein 2 | -0.0334211 |
| TPM4 | tropomyosin 4 | -0.0332364 |
| HMGA1 | high mobility group AT-hook 1 | -0.0330808 |
| RPS14 | ribosomal protein S14 | -0.0328864 |
| RPL11 | ribosomal protein L11 | -0.0327797 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.032306 |
| RPL38 | ribosomal protein L38 | -0.0321805 |
| RPS19 | ribosomal protein S19 | -0.0321352 |
| HLA-A | major histocompatibility complex, class I, A | -0.031791 |
| TUBB | tubulin, beta class I | -0.0317552 |
| RPL31 | ribosomal protein L31 | -0.0317221 |
| RPL36A | ribosomal protein L36a | -0.0316435 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0312367 |
| RPS29 | ribosomal protein S29 | -0.0311043 |
| RPL37A | ribosomal protein L37a | -0.0310744 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.030938 |
| RPS10 | ribosomal protein S10 | -0.0306042 |
| MED13L | mediator complex subunit 13-like | -0.0305327 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0303531 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.030171 |
| RPLP0 | ribosomal protein, large, P0 | -0.0301073 |
| RPS15 | ribosomal protein S15 | -0.0300222 |
| RPS16 | ribosomal protein S16 | -0.0298402 |
| NOP56 | NOP56 ribonucleoprotein | -0.0296576 |
| BPTF | bromodomain PHD finger transcription factor | -0.029579 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0294343 |
| RPS27A | ribosomal protein S27a | -0.0289825 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.028874 |
| NF1 | neurofibromin 1 | -0.0288177 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0287238 |
| DIAPH3 | diaphanous-related formin 3 | -0.0286789 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0284009 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0282854 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0280584 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.027599 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0275488 |
| VDAC1 | voltage-dependent anion channel 1 | -0.027503 |
| NDRG1 | N-myc downstream regulated 1 | -0.0272611 |
| MORC4 | MORC family CW-type zinc finger 4 | -0.0271193 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0269441 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0267794 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0264245 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0260467 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0258135 |
| KRT8 | keratin 8, type II | -0.0256601 |
| RPS17 | ribosomal protein S17 | -0.0254381 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.025171 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0250443 |
| NFIA | nuclear factor I/A | -0.025027 |
| RPS23 | ribosomal protein S23 | -0.024852 |
