| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.117954 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.117876 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.102796 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.101635 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0946914 |
| GOLGA4 | golgin A4 | 0.0933885 |
| MT2A | metallothionein 2A | 0.090462 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0884259 |
| GOLGB1 | golgin B1 | 0.0831054 |
| LAMB3 | laminin, beta 3 | 0.0829181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0769273 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0752278 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0752161 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0682781 |
| FLNB | filamin B, beta | 0.0668911 |
| RPS3 | ribosomal protein S3 | 0.0640981 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0633736 |
| PRELID2 | PRELI domain containing 2 | 0.0618308 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0613677 |
| NDRG1 | N-myc downstream regulated 1 | 0.0609482 |
| INTS6 | integrator complex subunit 6 | 0.0569219 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0561476 |
| TMF1 | TATA element modulatory factor 1 | 0.0555145 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0553645 |
| RPS2 | ribosomal protein S2 | 0.0530416 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0524095 |
| RPS6 | ribosomal protein S6 | 0.0491009 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0465684 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0463017 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0457233 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0455532 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0439719 |
| BRD2 | bromodomain containing 2 | 0.041702 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.040058 |
| CANX | calnexin | 0.0398482 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0396115 |
| ASPH | aspartate beta-hydroxylase | 0.0395163 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0394666 |
| PGM3 | phosphoglucomutase 3 | 0.0394122 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.039242 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0391073 |
| EZR | ezrin | 0.0386981 |
| SET | SET nuclear proto-oncogene | 0.0386364 |
| PCBP2 | poly(rC) binding protein 2 | 0.0370277 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0358334 |
| CLTC | clathrin, heavy chain (Hc) | 0.0357617 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0353758 |
| COG6 | component of oligomeric golgi complex 6 | 0.0353606 |
| BBX | bobby sox homolog (Drosophila) | 0.0347635 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0345462 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0344905 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0340136 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0339542 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0333613 |
| RPS12 | ribosomal protein S12 | 0.0333302 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0332353 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0332023 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0331462 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0331204 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0326451 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0318528 |
| DSPP | dentin sialophosphoprotein | 0.0317726 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316366 |
| RPL14 | ribosomal protein L14 | 0.0315608 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0315095 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0314738 |
| FNIP1 | folliculin interacting protein 1 | 0.0313441 |
| NKTR | natural killer cell triggering receptor | 0.031273 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0312168 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0310397 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0310224 |
| TPR | translocated promoter region, nuclear basket protein | 0.0306786 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0302665 |
| HYOU1 | hypoxia up-regulated 1 | 0.0300906 |
| TAPBP | TAP binding protein (tapasin) | 0.0300599 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0299938 |
| HELZ | helicase with zinc finger | 0.0299482 |
| RUNX1 | runt-related transcription factor 1 | 0.0298865 |
| CALR | calreticulin | 0.0296347 |
| BRD4 | bromodomain containing 4 | 0.0295146 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0293058 |
| AFDN | afadin, adherens junction formation factor | 0.0291704 |
| ZNF638 | zinc finger protein 638 | 0.0291634 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0291294 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0288465 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0288123 |
| CENPF | centromere protein F, 350/400kDa | 0.0287975 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0286814 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0277155 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0276514 |
| VMP1 | vacuole membrane protein 1 | 0.0275827 |
| SFTPA2 | surfactant protein A2 | 0.0270364 |
| CTBP2 | C-terminal binding protein 2 | 0.0268649 |
| RPS8 | ribosomal protein S8 | 0.0267217 |
| RAD51B | RAD51 paralog B | 0.0266812 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0266596 |
| ATM | ATM serine/threonine kinase | 0.0266511 |
| CDK13 | cyclin-dependent kinase 13 | 0.0266031 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.026076 |
| RCOR1 | REST corepressor 1 | 0.0258891 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGB8 | integrin, beta 8 | -0.140883 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106101 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0872871 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0869905 |
| CCND1 | cyclin D1 | -0.066364 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0613109 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0607216 |
| TXNRD1 | thioredoxin reductase 1 | -0.0598828 |
| PAX8 | paired box 8 | -0.0598074 |
| KRT7 | keratin 7, type II | -0.0559732 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0554934 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0532482 |
| ANXA2 | annexin A2 | -0.0520408 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0500349 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0482552 |
| VCL | vinculin | -0.0471825 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0466921 |
| HMGA1 | high mobility group AT-hook 1 | -0.0464073 |
| SVIL | supervillin | -0.0444781 |
| RPLP1 | ribosomal protein, large, P1 | -0.0434068 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0432027 |
| RPS24 | ribosomal protein S24 | -0.0423062 |
| NF1 | neurofibromin 1 | -0.0421072 |
| TMSB10 | thymosin beta 10 | -0.0409923 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0387569 |
| WWC1 | WW and C2 domain containing 1 | -0.0383408 |
| RPS16 | ribosomal protein S16 | -0.0379983 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0371471 |
| FTL | ferritin, light polypeptide | -0.0368364 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.036359 |
| ATG7 | autophagy related 7 | -0.036128 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0360681 |
| S100A6 | S100 calcium binding protein A6 | -0.0351895 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0346063 |
| FIGN | fidgetin | -0.034594 |
| TUBB | tubulin, beta class I | -0.0341031 |
| PKM | pyruvate kinase, muscle | -0.0337339 |
| LAMA4 | laminin, alpha 4 | -0.0333919 |
| MATR3 | matrin 3 | -0.0332216 |
| TPM4 | tropomyosin 4 | -0.0331652 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0329071 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327874 |
| ARF1 | ADP-ribosylation factor 1 | -0.0322606 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0321012 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0312225 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0311295 |
| HMGA2 | high mobility group AT-hook 2 | -0.0310974 |
| LDHA | lactate dehydrogenase A | -0.030923 |
| EGFR | epidermal growth factor receptor | -0.0306163 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0303351 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.029946 |
| PCED1B | PC-esterase domain containing 1B | -0.0294911 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.029454 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0290938 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0285417 |
| TMSB4X | thymosin beta 4, X-linked | -0.0284931 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0276198 |
| ACTG1 | actin gamma 1 | -0.0271588 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0270208 |
| RPLP0 | ribosomal protein, large, P0 | -0.0269555 |
| GDA | guanine deaminase | -0.0267224 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0265582 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0263193 |
| CLDN1 | claudin 1 | -0.0260454 |
| TUBA1B | tubulin, alpha 1b | -0.025667 |
| RPS5 | ribosomal protein S5 | -0.0254859 |
| PLCB4 | phospholipase C, beta 4 | -0.0249972 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0246576 |
| R3HDM1 | R3H domain containing 1 | -0.0239721 |
| EREG | epiregulin | -0.0236173 |
| S100A10 | S100 calcium binding protein A10 | -0.0234936 |
| TKT | transketolase | -0.023326 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0232096 |
| PERP | PERP, TP53 apoptosis effector | -0.0230536 |
| CD44 | CD44 molecule (Indian blood group) | -0.0227413 |
| SBF2 | SET binding factor 2 | -0.0226531 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.022604 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.022322 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0221308 |
| WDR45B | WD repeat domain 45B | -0.0220044 |
| MGLL | monoglyceride lipase | -0.0219043 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0216479 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0215747 |
| IER3 | immediate early response 3 | -0.0215149 |
| RBM27 | RNA binding motif protein 27 | -0.0214918 |
| EMP1 | epithelial membrane protein 1 | -0.0214365 |
| HMGB1 | high mobility group box 1 | -0.0211741 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0211505 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0210304 |
| EGR1 | early growth response 1 | -0.0210052 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0209594 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0209369 |
| TMEM123 | transmembrane protein 123 | -0.0209086 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0208402 |
| RPS25 | ribosomal protein S25 | -0.0206257 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0205918 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0203898 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0202998 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.019916 |
| USP3 | ubiquitin specific peptidase 3 | -0.019854 |
