| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.157834 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.127018 |
| LAMB3 | laminin, beta 3 | 0.0863334 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0825454 |
| RPS6 | ribosomal protein S6 | 0.0755854 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0754872 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0740033 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0725435 |
| PTMA | prothymosin, alpha | 0.0619622 |
| RPS3 | ribosomal protein S3 | 0.0606486 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0596533 |
| AHNAK | AHNAK nucleoprotein | 0.0554809 |
| DST | dystonin | 0.0537663 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0537022 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0496886 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0475816 |
| DUSP6 | dual specificity phosphatase 6 | 0.0468356 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0463375 |
| RPS8 | ribosomal protein S8 | 0.0456113 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0443496 |
| GOLGB1 | golgin B1 | 0.0443122 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0441176 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0435378 |
| CD44 | CD44 molecule (Indian blood group) | 0.0433675 |
| RPS12 | ribosomal protein S12 | 0.0427088 |
| CAVIN1 | caveolae associated protein 1 | 0.0426737 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0398898 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0397141 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0387919 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0385956 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0382402 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.03604 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0358586 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0356965 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0353519 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.03521 |
| CAPRIN2 | caprin family member 2 | 0.0347342 |
| SEPTIN9 | septin 9 | 0.0347336 |
| RPL26 | ribosomal protein L26 | 0.0344127 |
| VCL | vinculin | 0.0342343 |
| RPL37A | ribosomal protein L37a | 0.0341877 |
| RPL12 | ribosomal protein L12 | 0.0336301 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0335836 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0330838 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0323028 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0308634 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0306588 |
| MAP1B | microtubule-associated protein 1B | 0.0297955 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0297416 |
| RRM2 | ribonucleotide reductase M2 | 0.0296699 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0294155 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0293202 |
| RRBP1 | ribosome binding protein 1 | 0.0289445 |
| EGFR | epidermal growth factor receptor | 0.0288335 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0285208 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.02814 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0281055 |
| SFTPA2 | surfactant protein A2 | 0.0280783 |
| VMP1 | vacuole membrane protein 1 | 0.0279759 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0278211 |
| MSN | moesin | 0.0277932 |
| ACTN4 | actinin, alpha 4 | 0.0272767 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0266803 |
| BRD2 | bromodomain containing 2 | 0.0262266 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0261779 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0259263 |
| RPL14 | ribosomal protein L14 | 0.0258485 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0255629 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0255372 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0255195 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.025138 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0250243 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0250019 |
| RPS17 | ribosomal protein S17 | 0.0249046 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247895 |
| RPS27A | ribosomal protein S27a | 0.0247675 |
| JAG1 | jagged 1 | 0.0246667 |
| DSPP | dentin sialophosphoprotein | 0.0242339 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0239579 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0237212 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0235802 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0235644 |
| RPS2 | ribosomal protein S2 | 0.0235136 |
| PLEC | plectin | 0.0235007 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.023496 |
| RPL23 | ribosomal protein L23 | 0.0233701 |
| RPL34 | ribosomal protein L34 | 0.0233398 |
| GRAMD1B | GRAM domain containing 1B | 0.0233298 |
| GOLGA4 | golgin A4 | 0.0233166 |
| H1-4 | H1.4 linker histone, cluster member | 0.0231866 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0231432 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.022799 |
| SQSTM1 | sequestosome 1 | 0.02267 |
| RPS21 | ribosomal protein S21 | 0.0226674 |
| CENPF | centromere protein F, 350/400kDa | 0.0226648 |
| MKI67 | marker of proliferation Ki-67 | 0.0225265 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0224354 |
| TOP1 | topoisomerase (DNA) I | 0.0223528 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0221952 |
| RPL11 | ribosomal protein L11 | 0.0221625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.276265 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.235239 |
| FN1 | fibronectin 1 | -0.201293 |
| IGF2 | insulin-like growth factor 2 | -0.18197 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.14748 |
| CDH13 | cadherin 13 | -0.119275 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.103518 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0966036 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0799309 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0795994 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0781216 |
| EGR1 | early growth response 1 | -0.0775207 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0719098 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.064377 |
| LOX | lysyl oxidase | -0.0628126 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0602435 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0589608 |
| TENM2 | teneurin transmembrane protein 2 | -0.0580203 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0577393 |
| NDRG1 | N-myc downstream regulated 1 | -0.0569432 |
| GLIS3 | GLIS family zinc finger 3 | -0.0558072 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0557326 |
| CCND1 | cyclin D1 | -0.052302 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0507241 |
| FAM13A | family with sequence similarity 13, member A | -0.0486466 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0469409 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0462735 |
| NGLY1 | N-glycanase 1 | -0.0420378 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0418003 |
| PKM | pyruvate kinase, muscle | -0.0412196 |
| STC1 | stanniocalcin 1 | -0.0409854 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0407141 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0403772 |
| ASPH | aspartate beta-hydroxylase | -0.0381011 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0364703 |
| SBF2 | SET binding factor 2 | -0.0345307 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0343921 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0343885 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0316301 |
| HMGA1 | high mobility group AT-hook 1 | -0.0314926 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0314437 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0313595 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0312197 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0310846 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0305789 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0304803 |
| PDE10A | phosphodiesterase 10A | -0.0299984 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0296815 |
| TMEM165 | transmembrane protein 165 | -0.0293334 |
| CALU | calumenin | -0.0291337 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0287256 |
| ZNF207 | zinc finger protein 207 | -0.0286145 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.027581 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0273964 |
| PGK1 | phosphoglycerate kinase 1 | -0.0273451 |
| ZNF292 | zinc finger protein 292 | -0.0264507 |
| CDCP1 | CUB domain containing protein 1 | -0.0263886 |
| TPM4 | tropomyosin 4 | -0.0261354 |
| HMGA2 | high mobility group AT-hook 2 | -0.0260393 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0259944 |
| USP3 | ubiquitin specific peptidase 3 | -0.0259602 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0257634 |
| SEC24A | SEC24 family member A | -0.0252447 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0251744 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0250887 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0246019 |
| GNAS | GNAS complex locus | -0.024434 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0235797 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0233017 |
| ARF4 | ADP-ribosylation factor 4 | -0.0233012 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0231258 |
| CLMP | CXADR-like membrane protein | -0.0230834 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0230795 |
| TPM1 | tropomyosin 1 (alpha) | -0.0230175 |
| FOSL1 | FOS-like antigen 1 | -0.0226441 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0225439 |
| USP34 | ubiquitin specific peptidase 34 | -0.0224794 |
| MMP12 | matrix metallopeptidase 12 | -0.022384 |
| CUX1 | cut-like homeobox 1 | -0.0222669 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0221545 |
| CD109 | CD109 molecule | -0.0221485 |
| RIN2 | Ras and Rab interactor 2 | -0.021933 |
| RNF24 | ring finger protein 24 | -0.0217102 |
| ADM | adrenomedullin | -0.0216841 |
| DIAPH2 | diaphanous-related formin 2 | -0.0216177 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0215441 |
| RLF | rearranged L-myc fusion | -0.0213998 |
| SP3 | Sp3 transcription factor | -0.0211418 |
| WDR45B | WD repeat domain 45B | -0.0208746 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0208198 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0208045 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0208004 |
| SETD5 | SET domain containing 5 | -0.0207732 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0205663 |
| ATG7 | autophagy related 7 | -0.0204713 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0203695 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0202979 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0201941 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0198881 |
| INSIG2 | insulin induced gene 2 | -0.0197988 |
