| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.100036 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0975494 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0918004 |
| STC1 | stanniocalcin 1 | 0.0852027 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0760806 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0655616 |
| AHNAK | AHNAK nucleoprotein | 0.0561058 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.054978 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0495214 |
| RND3 | Rho family GTPase 3 | 0.0491418 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.047004 |
| ASPH | aspartate beta-hydroxylase | 0.0469195 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0468647 |
| APP | amyloid beta (A4) precursor protein | 0.0440254 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0420908 |
| CALR | calreticulin | 0.0416493 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0405902 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0401365 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0391941 |
| CTSB | cathepsin B | 0.0372325 |
| RPS3 | ribosomal protein S3 | 0.0357974 |
| INHBA | inhibin, beta A | 0.0350026 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345855 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0340474 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0338346 |
| LDHA | lactate dehydrogenase A | 0.0309214 |
| MT2A | metallothionein 2A | 0.0307505 |
| ENO1 | enolase 1, (alpha) | 0.0302392 |
| SERINC1 | serine incorporator 1 | 0.0297713 |
| CANX | calnexin | 0.0290423 |
| COL3A1 | collagen, type III, alpha 1 | 0.028862 |
| NAV2 | neuron navigator 2 | 0.0285878 |
| RPS6 | ribosomal protein S6 | 0.0272807 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0269769 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0268744 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.02665 |
| SP100 | SP100 nuclear antigen | 0.0262424 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0258929 |
| VMP1 | vacuole membrane protein 1 | 0.0240129 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0238902 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0238075 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.023355 |
| KLF6 | Kruppel-like factor 6 | 0.0233171 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0229552 |
| CAVIN1 | caveolae associated protein 1 | 0.0226057 |
| TMF1 | TATA element modulatory factor 1 | 0.0222929 |
| MSN | moesin | 0.0222445 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0221424 |
| H1-4 | H1.4 linker histone, cluster member | 0.0220987 |
| ITGB5 | integrin, beta 5 | 0.0218485 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0218304 |
| PLEC | plectin | 0.0215505 |
| DUSP6 | dual specificity phosphatase 6 | 0.0215435 |
| TMSB4X | thymosin beta 4, X-linked | 0.0210971 |
| MAP4 | microtubule-associated protein 4 | 0.0209636 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0207963 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0206821 |
| H1-0 | H1.0 linker histone | 0.0206089 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0203743 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0201874 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0200966 |
| SFTPA2 | surfactant protein A2 | 0.0200511 |
| STK4 | serine/threonine kinase 4 | 0.0200446 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0193925 |
| OGA | O-GlcNAcase | 0.0193733 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0188902 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0183967 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0182417 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0181242 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0180603 |
| TPR | translocated promoter region, nuclear basket protein | 0.0179146 |
| HAS2 | hyaluronan synthase 2 | 0.0178949 |
| ARRDC3 | arrestin domain containing 3 | 0.0178875 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0178124 |
| RPL26 | ribosomal protein L26 | 0.0177808 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0177622 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0176836 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0174972 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.017486 |
| HLA-B | major histocompatibility complex, class I, B | 0.0174132 |
| HMGA2 | high mobility group AT-hook 2 | 0.0173828 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0172192 |
| BRD2 | bromodomain containing 2 | 0.0170777 |
| RRBP1 | ribosome binding protein 1 | 0.0169456 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0167848 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0166789 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.016501 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0162158 |
| TDRD7 | tudor domain containing 7 | 0.0160221 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0159858 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.015937 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0159241 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0158937 |
| RAB10 | RAB10, member RAS oncogene family | 0.0158694 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0157555 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0157215 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0157002 |
| COL1A1 | collagen, type I, alpha 1 | 0.015553 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0155344 |
| NKTR | natural killer cell triggering receptor | 0.0154343 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM1 | cell adhesion molecule 1 | -0.183557 |
| NDRG1 | N-myc downstream regulated 1 | -0.177252 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.144775 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.126736 |
| FN1 | fibronectin 1 | -0.114854 |
| CDH13 | cadherin 13 | -0.10977 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0990353 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0910197 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0885362 |
| FNDC3B | fibronectin type III domain containing 3B | -0.084204 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0783091 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.07014 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0692299 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0685339 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0614261 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.061232 |
| CALD1 | caldesmon 1 | -0.0582577 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0575292 |
| EGFR | epidermal growth factor receptor | -0.0559839 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0527034 |
| ATP13A3 | ATPase type 13A3 | -0.0525974 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0516888 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0516405 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.05137 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0501952 |
| VCAN | versican | -0.0491671 |
| PDE10A | phosphodiesterase 10A | -0.0491593 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0490976 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0475549 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0446788 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0430263 |
| RUNX1 | runt-related transcription factor 1 | -0.0420557 |
| FBN1 | fibrillin 1 | -0.0412174 |
| IER3 | immediate early response 3 | -0.040449 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0395888 |
| CD109 | CD109 molecule | -0.039466 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0386746 |
| COL1A2 | collagen, type I, alpha 2 | -0.0385318 |
| LOX | lysyl oxidase | -0.0371243 |
| QKI | QKI, KH domain containing, RNA binding | -0.0367759 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0364332 |
| CD44 | CD44 molecule (Indian blood group) | -0.0345889 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0345514 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0344393 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0342434 |
| VEGFA | vascular endothelial growth factor A | -0.0341074 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0339157 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0337692 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.03358 |
| PRR16 | proline rich 16 | -0.0335055 |
| GOLGA4 | golgin A4 | -0.0331415 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0331002 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0330188 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0328584 |
| COL5A1 | collagen, type V, alpha 1 | -0.0326422 |
| KIF13A | kinesin family member 13A | -0.0325946 |
| IL6ST | interleukin 6 signal transducer | -0.0323488 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0323339 |
| PKM | pyruvate kinase, muscle | -0.0320368 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0316301 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0313056 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0310887 |
| HMGA1 | high mobility group AT-hook 1 | -0.0310605 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0310438 |
| EGR1 | early growth response 1 | -0.0306222 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0302914 |
| TENM3 | teneurin transmembrane protein 3 | -0.0300581 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0297413 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0293968 |
| TBC1D23 | TBC1 domain family, member 23 | -0.029098 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0286756 |
| TPM1 | tropomyosin 1 (alpha) | -0.028667 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0286143 |
| CNTN5 | contactin 5 | -0.0284797 |
| TFG | TRK-fused gene | -0.0280005 |
| FTL | ferritin, light polypeptide | -0.0279557 |
| MTDH | metadherin | -0.0279287 |
| MATR3 | matrin 3 | -0.0276761 |
| TRAM1 | translocation associated membrane protein 1 | -0.0275941 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0275734 |
| TMEM165 | transmembrane protein 165 | -0.0274884 |
| VIM | vimentin | -0.0274328 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0274042 |
| ICAM1 | intercellular adhesion molecule 1 | -0.027262 |
| ARF4 | ADP-ribosylation factor 4 | -0.027174 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0269645 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0266798 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0262349 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0262065 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0261016 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0258435 |
| COPA | coatomer protein complex, subunit alpha | -0.0251417 |
| SPAG9 | sperm associated antigen 9 | -0.0248736 |
| CLINT1 | clathrin interactor 1 | -0.0248712 |
| SEC24A | SEC24 family member A | -0.0244104 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0244092 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0243503 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0243058 |
| RYBP | RING1 and YY1 binding protein | -0.0241837 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0237052 |
