| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.176501 |
| RPS3 | ribosomal protein S3 | 0.0966302 |
| RPS6 | ribosomal protein S6 | 0.0781878 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0770032 |
| PLK2 | polo-like kinase 2 | 0.0685737 |
| RPL23 | ribosomal protein L23 | 0.0590199 |
| RPS12 | ribosomal protein S12 | 0.0587649 |
| BCL2L1 | BCL2-like 1 | 0.0573493 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0572048 |
| STK24 | serine/threonine kinase 24 | 0.0548994 |
| ZFP36 | ZFP36 ring finger protein | 0.0543389 |
| TJP1 | tight junction protein 1 | 0.0493897 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0489039 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0488705 |
| RPS2 | ribosomal protein S2 | 0.0487653 |
| NTN4 | netrin 4 | 0.0483403 |
| RPS19 | ribosomal protein S19 | 0.0462204 |
| VMP1 | vacuole membrane protein 1 | 0.0457201 |
| SMAD3 | SMAD family member 3 | 0.0448036 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0443545 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.044098 |
| B2M | beta-2-microglobulin | 0.0423521 |
| RPS8 | ribosomal protein S8 | 0.0416085 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0415767 |
| GOLGB1 | golgin B1 | 0.040618 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0395131 |
| AREG | amphiregulin | 0.039284 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0388185 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0383544 |
| RPL18 | ribosomal protein L18 | 0.0381175 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0374748 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0359959 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0358949 |
| DST | dystonin | 0.0358277 |
| FAT1 | FAT atypical cadherin 1 | 0.0356324 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0349216 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0345524 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0338832 |
| FLNB | filamin B, beta | 0.0336088 |
| GOLGA4 | golgin A4 | 0.0324713 |
| MSN | moesin | 0.0322543 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0321647 |
| UTRN | utrophin | 0.0317695 |
| SET | SET nuclear proto-oncogene | 0.0306493 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0305993 |
| AFDN | afadin, adherens junction formation factor | 0.0302636 |
| HYOU1 | hypoxia up-regulated 1 | 0.0302433 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0295606 |
| SMC1A | structural maintenance of chromosomes 1A | 0.029243 |
| CENPF | centromere protein F, 350/400kDa | 0.0291773 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0289662 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0289654 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0286516 |
| ANKRD11 | ankyrin repeat domain 11 | 0.028031 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0278942 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0273094 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0270551 |
| CCNYL1 | cyclin Y-like 1 | 0.0268983 |
| CLDN4 | claudin 4 | 0.0267881 |
| PPL | periplakin | 0.0266454 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.026574 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0265576 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0264752 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0263102 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0261374 |
| RPL21 | ribosomal protein L21 | 0.0258861 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0258442 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0257319 |
| KLF6 | Kruppel-like factor 6 | 0.0255297 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0253729 |
| CTBP2 | C-terminal binding protein 2 | 0.0252908 |
| RBM39 | RNA binding motif protein 39 | 0.0251565 |
| LIMA1 | LIM domain and actin binding 1 | 0.0249294 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0247183 |
| LMNA | lamin A/C | 0.0246079 |
| YBX3 | Y box binding protein 3 | 0.0244021 |
| RPS21 | ribosomal protein S21 | 0.0243063 |
| PHF20L1 | PHD finger protein 20-like 1 | 0.0242116 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0240967 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0239218 |
| TPM3 | tropomyosin 3 | 0.0238 |
| BRD2 | bromodomain containing 2 | 0.0236549 |
| CBX3 | chromobox homolog 3 | 0.0235917 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0235137 |
| RBM25 | RNA binding motif protein 25 | 0.0235079 |
| VEGFA | vascular endothelial growth factor A | 0.023246 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0231984 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0231885 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0231753 |
| CLIC5 | chloride intracellular channel 5 | 0.0231305 |
| POTEF | POTE ankyrin domain family, member F | 0.0230252 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0230236 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0229773 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0229534 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0228965 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0226815 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0225386 |
| RPL9 | ribosomal protein L9 | 0.02247 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0224366 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0223428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRY | furry homolog (Drosophila) | -0.15146 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.149967 |
| LYZ | lysozyme | -0.114235 |
| ANXA2 | annexin A2 | -0.10836 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.107847 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0859222 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0837239 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0797213 |
| DIAPH2 | diaphanous-related formin 2 | -0.0761966 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0725538 |
| KRT20 | keratin 20, type I | -0.0654878 |
| RPLP1 | ribosomal protein, large, P1 | -0.0648978 |
| TMEM123 | transmembrane protein 123 | -0.0628904 |
| NDRG1 | N-myc downstream regulated 1 | -0.0608892 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0604161 |
| MMP7 | matrix metallopeptidase 7 | -0.0581608 |
| AGR2 | anterior gradient 2 | -0.0578291 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0563801 |
| DGKH | diacylglycerol kinase, eta | -0.0558628 |
| RPS24 | ribosomal protein S24 | -0.0546354 |
| SQSTM1 | sequestosome 1 | -0.0545799 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0530617 |
| AHNAK | AHNAK nucleoprotein | -0.0527542 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0511982 |
| LAMA4 | laminin, alpha 4 | -0.050891 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0500882 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0478157 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.047799 |
| TMEM65 | transmembrane protein 65 | -0.0444699 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0441776 |
| INSIG1 | insulin induced gene 1 | -0.0440744 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0439048 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0438377 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.0430778 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0426906 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0421794 |
| S100A6 | S100 calcium binding protein A6 | -0.0416715 |
| PKM | pyruvate kinase, muscle | -0.0416211 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0415915 |
| GNAS | GNAS complex locus | -0.0410736 |
| WDR45B | WD repeat domain 45B | -0.0407066 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0399775 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.039807 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0395909 |
| POF1B | premature ovarian failure, 1B | -0.0394158 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.038002 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0379217 |
| PCED1B | PC-esterase domain containing 1B | -0.0377215 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0374789 |
| RPS25 | ribosomal protein S25 | -0.0368624 |
| KRT8 | keratin 8, type II | -0.0366421 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.036598 |
| SDC4 | syndecan 4 | -0.0361138 |
| FOXO3 | forkhead box O3 | -0.0350595 |
| SLC45A4 | solute carrier family 45, member 4 | -0.035031 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0346335 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0345628 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0343097 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0341965 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0340532 |
| LDHA | lactate dehydrogenase A | -0.0339526 |
| PRELID2 | PRELI domain containing 2 | -0.0332461 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0331734 |
| PTK2 | protein tyrosine kinase 2 | -0.0328675 |
| RNF213 | ring finger protein 213 | -0.031267 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0311108 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0310395 |
| INTS6 | integrator complex subunit 6 | -0.030891 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0308836 |
| ADIPOR2 | adiponectin receptor 2 | -0.030842 |
| HM13 | histocompatibility (minor) 13 | -0.0301029 |
| FBXO32 | F-box protein 32 | -0.0296228 |
| TFRC | transferrin receptor | -0.0291689 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0291151 |
| SDCBP | syndecan binding protein (syntenin) | -0.0287877 |
| NF1 | neurofibromin 1 | -0.0287295 |
| RPS16 | ribosomal protein S16 | -0.0287038 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0286033 |
| PGK1 | phosphoglycerate kinase 1 | -0.0282474 |
| ARF1 | ADP-ribosylation factor 1 | -0.0280319 |
| EFNA5 | ephrin-A5 | -0.0280318 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.027853 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0277155 |
| RPL27A | ribosomal protein L27a | -0.0276634 |
| SERINC5 | serine incorporator 5 | -0.0274792 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0272285 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0271399 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0267455 |
| RTN3 | reticulon 3 | -0.0263812 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0259267 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0256792 |
| TES | testin LIM domain protein | -0.0255669 |
| EGR1 | early growth response 1 | -0.0255211 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0255176 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0252844 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.025153 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0251411 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0251129 |
| RPLP0 | ribosomal protein, large, P0 | -0.0250177 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0249732 |
