| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.260059 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.123493 |
| DSPP | dentin sialophosphoprotein | 0.106594 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0949734 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.08978 |
| RPS12 | ribosomal protein S12 | 0.089707 |
| FAM107B | family with sequence similarity 107, member B | 0.0872868 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0658199 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0629155 |
| SVIL | supervillin | 0.0626555 |
| NDRG1 | N-myc downstream regulated 1 | 0.0618996 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0605417 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0604706 |
| ASPH | aspartate beta-hydroxylase | 0.0603463 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0569758 |
| RPS3 | ribosomal protein S3 | 0.0547374 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0543817 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.053904 |
| RPL37A | ribosomal protein L37a | 0.0475716 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.045627 |
| RPL26 | ribosomal protein L26 | 0.0455481 |
| RPS8 | ribosomal protein S8 | 0.0453419 |
| TF | transferrin | 0.0450172 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0432836 |
| RPS6 | ribosomal protein S6 | 0.0428186 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0422397 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0405616 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0363869 |
| RPL11 | ribosomal protein L11 | 0.0362286 |
| RACK1 | receptor for activated C kinase 1 | 0.0342164 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0327491 |
| RPS2 | ribosomal protein S2 | 0.0323522 |
| LDHA | lactate dehydrogenase A | 0.0322514 |
| MT2A | metallothionein 2A | 0.0304752 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0304408 |
| FOXP1 | forkhead box P1 | 0.0302064 |
| TMF1 | TATA element modulatory factor 1 | 0.0295365 |
| GOLGA4 | golgin A4 | 0.0291314 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0285993 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0284091 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0276921 |
| SFTPA2 | surfactant protein A2 | 0.027483 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0270719 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0269322 |
| VMP1 | vacuole membrane protein 1 | 0.026775 |
| KYNU | kynureninase | 0.026177 |
| CTSB | cathepsin B | 0.0260884 |
| VEGFA | vascular endothelial growth factor A | 0.025861 |
| CRY1 | cryptochrome circadian clock 1 | 0.0257672 |
| BRD2 | bromodomain containing 2 | 0.025337 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0252073 |
| DST | dystonin | 0.0250542 |
| ENO1 | enolase 1, (alpha) | 0.0249817 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0247971 |
| RPS17 | ribosomal protein S17 | 0.0246519 |
| TNS1 | tensin 1 | 0.0245942 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0245214 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0243017 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0236235 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0235386 |
| GOLGB1 | golgin B1 | 0.0234423 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0232099 |
| RPL37 | ribosomal protein L37 | 0.0226124 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.0219203 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0218996 |
| JAK1 | Janus kinase 1 | 0.021787 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0217557 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0215458 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0213648 |
| RPL9 | ribosomal protein L9 | 0.0211892 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0211611 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0210778 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0209099 |
| DUSP6 | dual specificity phosphatase 6 | 0.0207949 |
| TCIM | transcriptional and immune response regulator | 0.0206716 |
| BRD4 | bromodomain containing 4 | 0.0203953 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0203127 |
| B2M | beta-2-microglobulin | 0.0202671 |
| OPTN | optineurin | 0.0201738 |
| RPL14 | ribosomal protein L14 | 0.0197814 |
| SERINC1 | serine incorporator 1 | 0.0190369 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0189717 |
| ACTG1 | actin gamma 1 | 0.0188308 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0187875 |
| KLF6 | Kruppel-like factor 6 | 0.0187183 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0186063 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.018483 |
| SET | SET nuclear proto-oncogene | 0.0184794 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0183974 |
| STK17A | serine/threonine kinase 17a | 0.0182551 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0179825 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0177817 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0176698 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0175452 |
| MTSS1 | metastasis suppressor 1 | 0.0173775 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0173741 |
| FAT1 | FAT atypical cadherin 1 | 0.0172946 |
| ITGA6 | integrin, alpha 6 | 0.0172667 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0170108 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0169489 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.335563 |
| APOB | apolipoprotein B | -0.170358 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.135924 |
| FNDC3B | fibronectin type III domain containing 3B | -0.129828 |
| APOA2 | apolipoprotein A-II | -0.113256 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0977373 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0922442 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0757837 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0742281 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0733945 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0724247 |
| TMEM123 | transmembrane protein 123 | -0.0711844 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0700454 |
| GPC6 | glypican 6 | -0.0685161 |
| RNF213 | ring finger protein 213 | -0.0579614 |
| EHBP1 | EH domain binding protein 1 | -0.0552419 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0552183 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0539398 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0498069 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0481347 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0480988 |
| LYZ | lysozyme | -0.0467413 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0456827 |
| A2M | alpha-2-macroglobulin | -0.0446186 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0442052 |
| GPC3 | glypican 3 | -0.0439218 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436306 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0406595 |
| MSI2 | musashi RNA-binding protein 2 | -0.0402965 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0389006 |
| GNAS | GNAS complex locus | -0.0373112 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0370658 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0361585 |
| APOE | apolipoprotein E | -0.0351829 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0339682 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0339084 |
| C3 | complement component 3 | -0.0338653 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0337881 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0336613 |
| NHSL1 | NHS-like 1 | -0.0324748 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0318812 |
| CP | ceruloplasmin (ferroxidase) | -0.0315624 |
| TRIM26 | tripartite motif containing 26 | -0.0314733 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0313198 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0312253 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0309478 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0308388 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0305706 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0303942 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0300096 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.029778 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0294214 |
| OSMR | oncostatin M receptor | -0.0291815 |
| PARD3 | par-3 family cell polarity regulator | -0.0285645 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0285284 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0285256 |
| FN1 | fibronectin 1 | -0.0282434 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0281894 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0281179 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0279739 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0279406 |
| ZFHX3 | zinc finger homeobox 3 | -0.0278935 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0278691 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0275625 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0275013 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0274353 |
| RPS24 | ribosomal protein S24 | -0.0273579 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0269186 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0268923 |
| PEG3 | paternally expressed 3 | -0.026848 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266125 |
| CNKSR3 | CNKSR family member 3 | -0.0262434 |
| ITGA1 | integrin, alpha 1 | -0.026042 |
| GLG1 | golgi glycoprotein 1 | -0.0258358 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0257932 |
| ITGAV | integrin, alpha V | -0.025791 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0255737 |
| RBM39 | RNA binding motif protein 39 | -0.025562 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.025498 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0250017 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0249789 |
| FAM135A | family with sequence similarity 135, member A | -0.0249788 |
| NPR2 | natriuretic peptide receptor 2 | -0.0247202 |
| NFIA | nuclear factor I/A | -0.0247003 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0244312 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0242394 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0239347 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0238931 |
| MATN3 | matrilin 3 | -0.0237568 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0233691 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0233135 |
| PTK2 | protein tyrosine kinase 2 | -0.0233031 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0231625 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.023017 |
| TCF12 | transcription factor 12 | -0.0229883 |
| PTCHD4 | patched domain containing 4 | -0.0226962 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0222707 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0219537 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0218009 |
| ZNF207 | zinc finger protein 207 | -0.0217957 |
