| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0663805 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0631808 |
| INTS6 | integrator complex subunit 6 | 0.061974 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0591237 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0586935 |
| ASPH | aspartate beta-hydroxylase | 0.0577101 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0548659 |
| VCL | vinculin | 0.0536905 |
| PRELID2 | PRELI domain containing 2 | 0.0515338 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0500272 |
| SMAD3 | SMAD family member 3 | 0.0478077 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0473726 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0470945 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0467235 |
| DST | dystonin | 0.0455666 |
| SEPTIN9 | septin 9 | 0.0418253 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0410209 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0408792 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0399258 |
| FOXO1 | forkhead box O1 | 0.0386994 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0380106 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0378215 |
| AHNAK | AHNAK nucleoprotein | 0.0373805 |
| LMO7 | LIM domain 7 | 0.0354932 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0337525 |
| LUZP1 | leucine zipper protein 1 | 0.0336432 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0332877 |
| FN1 | fibronectin 1 | 0.0331293 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0331175 |
| CAPRIN2 | caprin family member 2 | 0.0320793 |
| EFNA5 | ephrin-A5 | 0.0319795 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0318295 |
| H1-0 | H1.0 linker histone | 0.0315746 |
| AOPEP | aminopeptidase O (putative) | 0.0315453 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0306949 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0288126 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0282647 |
| BCL2L1 | BCL2-like 1 | 0.0281153 |
| ACTN1 | actinin, alpha 1 | 0.0273371 |
| CLIC4 | chloride intracellular channel 4 | 0.0269571 |
| YBX3 | Y box binding protein 3 | 0.0259508 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0258512 |
| FOXP1 | forkhead box P1 | 0.0252523 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0251634 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0247066 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0246202 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0245215 |
| SMYD3 | SET and MYND domain containing 3 | 0.0244412 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.024181 |
| BLCAP | bladder cancer associated protein | 0.0241429 |
| MSN | moesin | 0.023628 |
| CUL4B | cullin 4B | 0.0229181 |
| ANO6 | anoctamin 6 | 0.0224731 |
| ARRDC3 | arrestin domain containing 3 | 0.0221987 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0220866 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0214309 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0214138 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0213594 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0212925 |
| APP | amyloid beta (A4) precursor protein | 0.0212445 |
| CTBP2 | C-terminal binding protein 2 | 0.0211357 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0209632 |
| RPL14 | ribosomal protein L14 | 0.0207888 |
| RIN2 | Ras and Rab interactor 2 | 0.020401 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0203307 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0202183 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0201771 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0200746 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0198783 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0197066 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0196702 |
| VMP1 | vacuole membrane protein 1 | 0.019635 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0195069 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.019399 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0193255 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0193146 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0190383 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0190051 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0186911 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0186407 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.018603 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.018308 |
| GOLGB1 | golgin B1 | 0.0180384 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0178394 |
| ATP11C | ATPase, class VI, type 11C | 0.0177745 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0177231 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0176308 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0175959 |
| TJP1 | tight junction protein 1 | 0.0175678 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0175668 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0175322 |
| ATM | ATM serine/threonine kinase | 0.0175254 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0172581 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0172277 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0171443 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0169403 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0168615 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0167826 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0167491 |
| HMGA2 | high mobility group AT-hook 2 | 0.016275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.334365 |
| NDRG1 | N-myc downstream regulated 1 | -0.127808 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.127352 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124272 |
| IGF2 | insulin-like growth factor 2 | -0.0740034 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0735158 |
| PTMA | prothymosin, alpha | -0.065124 |
| S100A10 | S100 calcium binding protein A10 | -0.0639789 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0600068 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0598989 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.059607 |
| EMP1 | epithelial membrane protein 1 | -0.0577878 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0528239 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0528215 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0509587 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0507971 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0496284 |
| TMSB10 | thymosin beta 10 | -0.0483629 |
| PGK1 | phosphoglycerate kinase 1 | -0.0483223 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0472787 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0449545 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.044864 |
| GNAS | GNAS complex locus | -0.0447371 |
| ENO1 | enolase 1, (alpha) | -0.0443259 |
| POTEF | POTE ankyrin domain family, member F | -0.0442351 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0436192 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0436148 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0435405 |
| SULF1 | sulfatase 1 | -0.0424679 |
| S100A11 | S100 calcium binding protein A11 | -0.0424108 |
| HM13 | histocompatibility (minor) 13 | -0.0415582 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0413878 |
| PODXL | podocalyxin-like | -0.041199 |
| LDHA | lactate dehydrogenase A | -0.0396978 |
| RPS13 | ribosomal protein S13 | -0.0390797 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390196 |
| RPS25 | ribosomal protein S25 | -0.0385286 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0383249 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0381691 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.036373 |
| S100A2 | S100 calcium binding protein A2 | -0.0357553 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0355359 |
| TMSB4X | thymosin beta 4, X-linked | -0.0351169 |
| HMGA1 | high mobility group AT-hook 1 | -0.0349989 |
| CALB1 | calbindin 1, 28kDa | -0.0339523 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.033791 |
| SULF2 | sulfatase 2 | -0.0331163 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330926 |
| RPL8 | ribosomal protein L8 | -0.03271 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0326983 |
| FTL | ferritin, light polypeptide | -0.0326858 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0326619 |
| RPS6 | ribosomal protein S6 | -0.0325962 |
| RPL36A | ribosomal protein L36a | -0.0324429 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.032187 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.031911 |
| RPL35A | ribosomal protein L35a | -0.0317803 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0317153 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0316509 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0313621 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0313286 |
| ANXA1 | annexin A1 | -0.0312268 |
| CSTB | cystatin B (stefin B) | -0.0306192 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0305694 |
| LAMA5 | laminin, alpha 5 | -0.0305075 |
| RPS8 | ribosomal protein S8 | -0.0304345 |
| RPS24 | ribosomal protein S24 | -0.0302292 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0299908 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0299753 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0298445 |
| PKM | pyruvate kinase, muscle | -0.0297452 |
| FOSL1 | FOS-like antigen 1 | -0.0295578 |
| S100A6 | S100 calcium binding protein A6 | -0.0293939 |
| CD44 | CD44 molecule (Indian blood group) | -0.0292442 |
| C4BPB | complement component 4 binding protein, beta | -0.0290956 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0290554 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0286082 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0279967 |
| TPM4 | tropomyosin 4 | -0.0278842 |
| FLNB | filamin B, beta | -0.0277452 |
| DSTN | destrin (actin depolymerizing factor) | -0.0276801 |
| RPL23 | ribosomal protein L23 | -0.0276122 |
| GOLGA4 | golgin A4 | -0.02751 |
| EFHD2 | EF-hand domain family, member D2 | -0.0268696 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0266225 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0265652 |
| EZR | ezrin | -0.0265395 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0262623 |
| RSF1 | remodeling and spacing factor 1 | -0.0261069 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0251002 |
| CSNK1E | casein kinase 1, epsilon | -0.0247456 |
| MYO10 | myosin X | -0.024734 |
| CDK6 | cyclin-dependent kinase 6 | -0.0246937 |
| ITGA6 | integrin, alpha 6 | -0.0246778 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0245499 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0243713 |
| ITGB4 | integrin, beta 4 | -0.024135 |
| RPL27A | ribosomal protein L27a | -0.0239455 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0238112 |
| NAV2 | neuron navigator 2 | -0.023764 |
