| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.386592 |
| MT2A | metallothionein 2A | 0.211467 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.178004 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.15145 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.10985 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0954434 |
| MT1X | metallothionein 1X | 0.0853078 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0781087 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0731437 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0704484 |
| ZNF841 | zinc finger protein 841 | 0.070245 |
| MSN | moesin | 0.0696289 |
| CENPF | centromere protein F, 350/400kDa | 0.0628975 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0626755 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0563456 |
| RPS6 | ribosomal protein S6 | 0.0541228 |
| RND3 | Rho family GTPase 3 | 0.0532108 |
| CD44 | CD44 molecule (Indian blood group) | 0.0523076 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0515237 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0514562 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0495851 |
| TPM3 | tropomyosin 3 | 0.0490949 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0481496 |
| RPS3 | ribosomal protein S3 | 0.0454925 |
| DST | dystonin | 0.0451753 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0426885 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.040409 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0401057 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0391605 |
| TAPBP | TAP binding protein (tapasin) | 0.0384002 |
| FLNB | filamin B, beta | 0.0380019 |
| SET | SET nuclear proto-oncogene | 0.037926 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0354041 |
| MKI67 | marker of proliferation Ki-67 | 0.0341925 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0333325 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0331918 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0325185 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0322935 |
| ANXA1 | annexin A1 | 0.0318367 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0313944 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0311945 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0311413 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0309366 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0307484 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0303897 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0302384 |
| YBX1 | Y box binding protein 1 | 0.0299105 |
| GOLGB1 | golgin B1 | 0.029704 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0296299 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0295906 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0292378 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0292329 |
| PRRC2C | proline-rich coiled-coil 2C | 0.028874 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283997 |
| FAM107B | family with sequence similarity 107, member B | 0.0280799 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0273895 |
| CALD1 | caldesmon 1 | 0.0270097 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0267236 |
| CORO1C | coronin, actin binding protein, 1C | 0.0265686 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0265097 |
| VMP1 | vacuole membrane protein 1 | 0.0263402 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0263122 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026227 |
| B2M | beta-2-microglobulin | 0.0258516 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.025743 |
| YBX3 | Y box binding protein 3 | 0.0251044 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0249542 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.024949 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0244818 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0243872 |
| MORF4L2 | mortality factor 4 like 2 | 0.0239495 |
| EZR | ezrin | 0.0235777 |
| FOSL1 | FOS-like antigen 1 | 0.0233698 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0231336 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0230911 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0228562 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0222918 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0222102 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0221039 |
| ERBIN | erbb2 interacting protein | 0.0218941 |
| RPS2 | ribosomal protein S2 | 0.0218694 |
| KIF5B | kinesin family member 5B | 0.0217909 |
| PCBP2 | poly(rC) binding protein 2 | 0.0215369 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0215218 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0211339 |
| TLN1 | talin 1 | 0.0209308 |
| BRD2 | bromodomain containing 2 | 0.0208337 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0206549 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0205776 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0205573 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0201978 |
| GOLGA4 | golgin A4 | 0.0201482 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0198645 |
| SFPQ | splicing factor proline/glutamine-rich | 0.019716 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0196384 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0195023 |
| CBX3 | chromobox homolog 3 | 0.0194576 |
| HMGB2 | high mobility group box 2 | 0.0192255 |
| RPL14 | ribosomal protein L14 | 0.0191529 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0190152 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.294278 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.188969 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.187506 |
| HLA-B | major histocompatibility complex, class I, B | -0.140182 |
| FTL | ferritin, light polypeptide | -0.135584 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123667 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0988596 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0798892 |
| PLCB4 | phospholipase C, beta 4 | -0.069084 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0680432 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0632441 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.060719 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0575177 |
| CTSD | cathepsin D | -0.0552951 |
| PKM | pyruvate kinase, muscle | -0.0546112 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0544366 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0542169 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0484139 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0478803 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0439177 |
| SULF1 | sulfatase 1 | -0.0410502 |
| GLIS3 | GLIS family zinc finger 3 | -0.0398509 |
| ZNF804A | zinc finger protein 804A | -0.0394278 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0392293 |
| RPLP1 | ribosomal protein, large, P1 | -0.0388961 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0381764 |
| POSTN | periostin, osteoblast specific factor | -0.036697 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0366643 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.036394 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0360299 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0359043 |
| GNAS | GNAS complex locus | -0.0335428 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0331126 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0328613 |
| VIM | vimentin | -0.0321709 |
| TNS3 | tensin 3 | -0.0318817 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0309201 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0299431 |
| HLA-A | major histocompatibility complex, class I, A | -0.0298418 |
| SBF2 | SET binding factor 2 | -0.0298083 |
| MAP4 | microtubule-associated protein 4 | -0.0295895 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0292392 |
| TMEM178B | transmembrane protein 178B | -0.0291984 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.028681 |
| RPS24 | ribosomal protein S24 | -0.0284927 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0272736 |
| PLIN2 | perilipin 2 | -0.0269385 |
| S100A6 | S100 calcium binding protein A6 | -0.0267912 |
| HLA-E | major histocompatibility complex, class I, E | -0.0264936 |
| KRT7 | keratin 7, type II | -0.0263557 |
| SQSTM1 | sequestosome 1 | -0.0263308 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0263159 |
| NUP58 | nucleoporin 58 | -0.0261112 |
| RPL7A | ribosomal protein L7a | -0.0257764 |
| DEK | DEK proto-oncogene | -0.0254115 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0253647 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0250865 |
| CUL4B | cullin 4B | -0.0250397 |
| FSTL1 | follistatin-like 1 | -0.0249861 |
| TPM1 | tropomyosin 1 (alpha) | -0.0249774 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0244025 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.02439 |
| TRAM1 | translocation associated membrane protein 1 | -0.0243863 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0241842 |
| TGFB2 | transforming growth factor, beta 2 | -0.0241611 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0239382 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0238006 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0233168 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0232821 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0232548 |
| TMSB10 | thymosin beta 10 | -0.0231405 |
| RPL27A | ribosomal protein L27a | -0.0231338 |
| COL5A2 | collagen, type V, alpha 2 | -0.0226083 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0226018 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0224693 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0223823 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0223517 |
| OSMR | oncostatin M receptor | -0.0222891 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0222514 |
| TENM3 | teneurin transmembrane protein 3 | -0.0220789 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0219843 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0217613 |
| CCND1 | cyclin D1 | -0.0214116 |
| ZNF432 | zinc finger protein 432 | -0.0211627 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0211371 |
| TPM4 | tropomyosin 4 | -0.0210457 |
| DIAPH3 | diaphanous-related formin 3 | -0.0210007 |
| MMP12 | matrix metallopeptidase 12 | -0.0209144 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0208045 |
| RPLP2 | ribosomal protein, large, P2 | -0.0207357 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0205254 |
| RHEB | Ras homolog enriched in brain | -0.0204722 |
| PTMA | prothymosin, alpha | -0.0204492 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0201859 |
| IER3 | immediate early response 3 | -0.0201104 |
| TKT | transketolase | -0.019707 |
| RPS16 | ribosomal protein S16 | -0.0196105 |
| AFAP1 | actin filament associated protein 1 | -0.0194312 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0192832 |
| NF1 | neurofibromin 1 | -0.0191562 |
