| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.185316 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.133312 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.120231 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.100001 |
| B2M | beta-2-microglobulin | 0.0926362 |
| AREG | amphiregulin | 0.0909958 |
| ASPH | aspartate beta-hydroxylase | 0.0877456 |
| ANXA1 | annexin A1 | 0.0870121 |
| RPS3 | ribosomal protein S3 | 0.0869404 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0844632 |
| EMP1 | epithelial membrane protein 1 | 0.0765328 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0689908 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0640957 |
| EZR | ezrin | 0.0630099 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0616026 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0597676 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0595238 |
| ITGA6 | integrin, alpha 6 | 0.0560948 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0530608 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0524936 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0521017 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0501143 |
| GOLGB1 | golgin B1 | 0.0499354 |
| DST | dystonin | 0.0435047 |
| LMNA | lamin A/C | 0.0433883 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0432943 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0427773 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0416607 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0411518 |
| TJP1 | tight junction protein 1 | 0.0408526 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.04 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0393432 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0391631 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.038401 |
| DSPP | dentin sialophosphoprotein | 0.0378569 |
| RPS12 | ribosomal protein S12 | 0.0375908 |
| VMP1 | vacuole membrane protein 1 | 0.0369968 |
| TMC5 | transmembrane channel-like 5 | 0.0367844 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0366801 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0353524 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0350076 |
| PTMA | prothymosin, alpha | 0.0350053 |
| TMSB4X | thymosin beta 4, X-linked | 0.0346708 |
| GDA | guanine deaminase | 0.034597 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0344648 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0343096 |
| MKI67 | marker of proliferation Ki-67 | 0.0333381 |
| ENO1 | enolase 1, (alpha) | 0.0332646 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0328626 |
| FAM107B | family with sequence similarity 107, member B | 0.0327994 |
| LAMB3 | laminin, beta 3 | 0.0327518 |
| YBX3 | Y box binding protein 3 | 0.032354 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.031815 |
| BRD2 | bromodomain containing 2 | 0.031295 |
| TMF1 | TATA element modulatory factor 1 | 0.0308421 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0307869 |
| HDAC9 | histone deacetylase 9 | 0.0307864 |
| CENPF | centromere protein F, 350/400kDa | 0.0305134 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0303215 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302003 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0300248 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0298372 |
| FBXO11 | F-box protein 11 | 0.0296097 |
| EDN1 | endothelin 1 | 0.0295895 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0295326 |
| LAMA4 | laminin, alpha 4 | 0.0293251 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0291483 |
| HKDC1 | hexokinase domain containing 1 | 0.0289067 |
| TAPBP | TAP binding protein (tapasin) | 0.028825 |
| FTL | ferritin, light polypeptide | 0.0286674 |
| SLK | STE20-like kinase | 0.0286537 |
| DSG2 | desmoglein 2 | 0.0285807 |
| FNIP1 | folliculin interacting protein 1 | 0.0281068 |
| SLTM | SAFB-like, transcription modulator | 0.0279537 |
| MYO1E | myosin IE | 0.0277364 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0275711 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0273829 |
| JUN | jun proto-oncogene | 0.0270811 |
| SFPQ | splicing factor proline/glutamine-rich | 0.026631 |
| RPL26 | ribosomal protein L26 | 0.0265141 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0262098 |
| KLF6 | Kruppel-like factor 6 | 0.0261702 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0261676 |
| EFNA5 | ephrin-A5 | 0.025911 |
| TOP1 | topoisomerase (DNA) I | 0.0258105 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0256919 |
| MYOF | myoferlin | 0.0255525 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0255329 |
| SET | SET nuclear proto-oncogene | 0.0255046 |
| RPL14 | ribosomal protein L14 | 0.0251686 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0251586 |
| FRMD5 | FERM domain containing 5 | 0.0246924 |
| SGMS2 | sphingomyelin synthase 2 | 0.0245814 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0244783 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.024335 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.024164 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0237248 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0233942 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0233406 |
| MCU | mitochondrial calcium uniporter | 0.0232717 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.118721 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.109496 |
| AGR2 | anterior gradient 2 | -0.109325 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107417 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105348 |
| NPSR1 | neuropeptide S receptor 1 | -0.104664 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.099879 |
| TMEM123 | transmembrane protein 123 | -0.0869514 |
| S100A6 | S100 calcium binding protein A6 | -0.0843921 |
| RPLP1 | ribosomal protein, large, P1 | -0.0756712 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0743519 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0622562 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0615483 |
| LOC112694756 | uncharaterized LOC112694756 | -0.059689 |
| RPS25 | ribosomal protein S25 | -0.0579382 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0554441 |
| INSIG1 | insulin induced gene 1 | -0.0551466 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0544279 |
| WDR45B | WD repeat domain 45B | -0.0495541 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0487528 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0456424 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0451367 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0447964 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0446283 |
| GPX2 | glutathione peroxidase 2 | -0.042953 |
| KRT8 | keratin 8, type II | -0.0422992 |
| RPS16 | ribosomal protein S16 | -0.0421636 |
| ITGB4 | integrin, beta 4 | -0.0417191 |
| RPS24 | ribosomal protein S24 | -0.0413342 |
| HM13 | histocompatibility (minor) 13 | -0.041005 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0401282 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0385098 |
| PRSS3 | protease, serine, 3 | -0.0384356 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0369792 |
| RPL39 | ribosomal protein L39 | -0.0368135 |
| TMSB10 | thymosin beta 10 | -0.0362211 |
| GNAS | GNAS complex locus | -0.0358327 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0349678 |
| TRAM1 | translocation associated membrane protein 1 | -0.0346695 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.03452 |
| LYZ | lysozyme | -0.0344447 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0341289 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0337977 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0333142 |
| HMGA1 | high mobility group AT-hook 1 | -0.0330143 |
| KRT18 | keratin 18, type I | -0.0328609 |
| MUC17 | mucin 17, cell surface associated | -0.0328204 |
| COG5 | component of oligomeric golgi complex 5 | -0.0324694 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0324396 |
| TRIM2 | tripartite motif containing 2 | -0.0315882 |
| ZNF207 | zinc finger protein 207 | -0.0306169 |
| ADIPOR2 | adiponectin receptor 2 | -0.0303317 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0303175 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.029964 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.029656 |
| PHKB | phosphorylase kinase, beta | -0.0295787 |
| RNF43 | ring finger protein 43 | -0.0292688 |
| RPS20 | ribosomal protein S20 | -0.029261 |
| TES | testin LIM domain protein | -0.0290883 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0282057 |
| S100A10 | S100 calcium binding protein A10 | -0.0277796 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0276014 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0272174 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0272158 |
| ARF1 | ADP-ribosylation factor 1 | -0.0269971 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0269912 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0262831 |
| TRAK1 | trafficking protein, kinesin binding 1 | -0.0262541 |
| AOPEP | aminopeptidase O (putative) | -0.0261852 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0261613 |
| WASF2 | WAS protein family, member 2 | -0.0261584 |
| ARCN1 | archain 1 | -0.0259161 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0257663 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0257392 |
| HLA-C | major histocompatibility complex, class I, C | -0.0256346 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0256329 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0256168 |
| MGAM2 | maltase-glucoamylase 2 (putative) | -0.0256019 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0254048 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0251367 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0250092 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0247911 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0247283 |
| RREB1 | ras responsive element binding protein 1 | -0.0244509 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -0.0243576 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0237787 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.02376 |
| RAB10 | RAB10, member RAS oncogene family | -0.0231162 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0230538 |
| CALU | calumenin | -0.0230126 |
| NEK6 | NIMA-related kinase 6 | -0.0229722 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0228641 |
| ACTN4 | actinin, alpha 4 | -0.0228204 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0227531 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.022689 |
| NF1 | neurofibromin 1 | -0.0224889 |
| NUP58 | nucleoporin 58 | -0.022421 |
| HMGB1 | high mobility group box 1 | -0.0224086 |
| RPL23 | ribosomal protein L23 | -0.0222543 |
| MSI2 | musashi RNA-binding protein 2 | -0.0220068 |
