| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.277682 |
| EXT1 | exostosin glycosyltransferase 1 | 0.20838 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.139026 |
| RPS6 | ribosomal protein S6 | 0.127746 |
| RPS3 | ribosomal protein S3 | 0.120033 |
| ASPH | aspartate beta-hydroxylase | 0.109826 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0985242 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0949842 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0884522 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0803966 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.079583 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0773676 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0745506 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0739972 |
| HDAC9 | histone deacetylase 9 | 0.0723431 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.071835 |
| MSN | moesin | 0.0685051 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0677688 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0645301 |
| CALD1 | caldesmon 1 | 0.064178 |
| RPS12 | ribosomal protein S12 | 0.0623545 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.061479 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0607667 |
| MYO10 | myosin X | 0.0576807 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0576618 |
| HMGA2 | high mobility group AT-hook 2 | 0.0566953 |
| RND3 | Rho family GTPase 3 | 0.0565837 |
| EFNA5 | ephrin-A5 | 0.0565421 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0547931 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0546784 |
| RUNX1 | runt-related transcription factor 1 | 0.053408 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0513685 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0513574 |
| ITGA6 | integrin, alpha 6 | 0.0506047 |
| RPS2 | ribosomal protein S2 | 0.0505743 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0504877 |
| BRD2 | bromodomain containing 2 | 0.0477173 |
| YBX3 | Y box binding protein 3 | 0.0476218 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0472917 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0468935 |
| MT2A | metallothionein 2A | 0.0467248 |
| JMJD1C | jumonji domain containing 1C | 0.0465769 |
| LIMA1 | LIM domain and actin binding 1 | 0.0461172 |
| NAV3 | neuron navigator 3 | 0.0446216 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0441832 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0440444 |
| RPS8 | ribosomal protein S8 | 0.0438476 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0436925 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0421286 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0419216 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0403908 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0388542 |
| TPM3 | tropomyosin 3 | 0.0380602 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0378632 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0368696 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.036722 |
| DOCK1 | dedicator of cytokinesis 1 | 0.035016 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0349047 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.034857 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0345632 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0343357 |
| RPL12 | ribosomal protein L12 | 0.0341462 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0337781 |
| INTS6 | integrator complex subunit 6 | 0.0331978 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0329669 |
| ZNF638 | zinc finger protein 638 | 0.0328445 |
| RPL26 | ribosomal protein L26 | 0.0326724 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0322232 |
| USP34 | ubiquitin specific peptidase 34 | 0.0322188 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0320049 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0315922 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0315503 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0312994 |
| RPS17 | ribosomal protein S17 | 0.0310246 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0303723 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0303704 |
| EGR1 | early growth response 1 | 0.0303565 |
| NABP1 | nucleic acid binding protein 1 | 0.0302565 |
| JUN | jun proto-oncogene | 0.0301229 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0300408 |
| RPL14 | ribosomal protein L14 | 0.0297318 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0294358 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0293936 |
| VMP1 | vacuole membrane protein 1 | 0.0293933 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0293819 |
| AHNAK | AHNAK nucleoprotein | 0.0293598 |
| RPL37A | ribosomal protein L37a | 0.0291963 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.028941 |
| FTL | ferritin, light polypeptide | 0.0289082 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0287826 |
| CORO1C | coronin, actin binding protein, 1C | 0.028417 |
| TXNIP | thioredoxin interacting protein | 0.0281244 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0280776 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0279991 |
| DST | dystonin | 0.0279878 |
| MCL1 | myeloid cell leukemia 1 | 0.0279133 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0277326 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0274387 |
| GPHN | gephyrin | 0.0271478 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0271016 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP12 | matrix metallopeptidase 12 | -0.160034 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.145699 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142856 |
| GPC6 | glypican 6 | -0.132872 |
| LSAMP | limbic system-associated membrane protein | -0.10585 |
| CD109 | CD109 molecule | -0.0875123 |
| VIM | vimentin | -0.0858432 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0837885 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0817374 |
| TMSB10 | thymosin beta 10 | -0.0739222 |
| ANXA2 | annexin A2 | -0.057175 |
| CDH13 | cadherin 13 | -0.0563862 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0559297 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0537391 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.053182 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0524556 |
| ZNF292 | zinc finger protein 292 | -0.0488296 |
| HMGA1 | high mobility group AT-hook 1 | -0.0472064 |
| DTNA | dystrobrevin, alpha | -0.046587 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0455124 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0452764 |
| NUP58 | nucleoporin 58 | -0.0450931 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0442975 |
| FN1 | fibronectin 1 | -0.0440952 |
| WDR45B | WD repeat domain 45B | -0.0432224 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0423107 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0414649 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0398229 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0383744 |
| GNAS | GNAS complex locus | -0.0379666 |
| PKM | pyruvate kinase, muscle | -0.0376278 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0370756 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0370297 |
| NDRG1 | N-myc downstream regulated 1 | -0.0363413 |
| ZNF207 | zinc finger protein 207 | -0.0358812 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0353017 |
| PTK2 | protein tyrosine kinase 2 | -0.0339517 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0335935 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0334534 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0332341 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0330142 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0328672 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0326202 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0325773 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0319483 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0316317 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0314485 |
| SPAG9 | sperm associated antigen 9 | -0.0312699 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0312328 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.030881 |
| BNC2 | basonuclin 2 | -0.0304401 |
| SMAD3 | SMAD family member 3 | -0.0304254 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0297839 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0294289 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0290106 |
| NLGN1 | neuroligin 1 | -0.028937 |
| SBF2 | SET binding factor 2 | -0.0288524 |
| MYOF | myoferlin | -0.028575 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0281141 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0280062 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0276367 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0275119 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0275013 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0274511 |
| TMEM123 | transmembrane protein 123 | -0.0274478 |
| PTCHD4 | patched domain containing 4 | -0.0271088 |
| USP3 | ubiquitin specific peptidase 3 | -0.0268267 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0262621 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0261594 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.025428 |
| TPM4 | tropomyosin 4 | -0.0252386 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0248655 |
| RNF145 | ring finger protein 145 | -0.0243966 |
| RLF | rearranged L-myc fusion | -0.0238536 |
| TENM2 | teneurin transmembrane protein 2 | -0.023655 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0234763 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0232544 |
| CDC73 | cell division cycle 73 | -0.0231093 |
| HELZ | helicase with zinc finger | -0.0231082 |
| RPS24 | ribosomal protein S24 | -0.0229622 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0229178 |
| LATS2 | large tumor suppressor kinase 2 | -0.0228631 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.022778 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0223896 |
| RPLP1 | ribosomal protein, large, P1 | -0.0223614 |
| MED13 | mediator complex subunit 13 | -0.0222238 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0221996 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0221317 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0218996 |
| NRP2 | neuropilin 2 | -0.0216887 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0216607 |
| SEPTIN7 | septin 7 | -0.0215454 |
| TFG | TRK-fused gene | -0.0211845 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0211737 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0211495 |
| TUBB | tubulin, beta class I | -0.0211336 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0208813 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0208578 |
| TRAM1 | translocation associated membrane protein 1 | -0.020722 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0207218 |
