| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.142079 |
| MT2A | metallothionein 2A | 0.109318 |
| SLTM | SAFB-like, transcription modulator | 0.0960367 |
| STC1 | stanniocalcin 1 | 0.0924094 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0840879 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0825431 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0802851 |
| AREG | amphiregulin | 0.0779083 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0668752 |
| YBX3 | Y box binding protein 3 | 0.0647264 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0640868 |
| RPS3 | ribosomal protein S3 | 0.0614595 |
| GOLGB1 | golgin B1 | 0.0614495 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0605028 |
| ASPH | aspartate beta-hydroxylase | 0.0569107 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0565059 |
| LAMC2 | laminin, gamma 2 | 0.0564359 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0550923 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0519771 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0516051 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0515226 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0505081 |
| HSPA8 | heat shock 70kDa protein 8 | 0.04996 |
| B2M | beta-2-microglobulin | 0.0487293 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0479507 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0478484 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0472709 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0465606 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0448655 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0446912 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0443851 |
| LMO7 | LIM domain 7 | 0.0435554 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0431517 |
| EGR1 | early growth response 1 | 0.0425119 |
| TMF1 | TATA element modulatory factor 1 | 0.0422821 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0420365 |
| LAMB3 | laminin, beta 3 | 0.0407073 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0403286 |
| TJP1 | tight junction protein 1 | 0.0403151 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0395533 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0394709 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.039142 |
| BRD2 | bromodomain containing 2 | 0.0388467 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0387671 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0384232 |
| EFNA5 | ephrin-A5 | 0.0380124 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0373901 |
| TPM3 | tropomyosin 3 | 0.0373603 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0370213 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0369479 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0368963 |
| EZR | ezrin | 0.0363367 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.036238 |
| MSN | moesin | 0.0359375 |
| SON | SON DNA binding protein | 0.0359049 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0355112 |
| JUN | jun proto-oncogene | 0.0354645 |
| SEC61G | Sec61 gamma subunit | 0.0353488 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0353041 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0351821 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0347685 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0345097 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0343797 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.034111 |
| ENO1 | enolase 1, (alpha) | 0.0337175 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0325836 |
| DSPP | dentin sialophosphoprotein | 0.0320653 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0318883 |
| ITSN2 | intersectin 2 | 0.0316577 |
| RBM25 | RNA binding motif protein 25 | 0.031617 |
| GOLGA4 | golgin A4 | 0.0312662 |
| FAM107B | family with sequence similarity 107, member B | 0.0311076 |
| SP100 | SP100 nuclear antigen | 0.0307159 |
| PMM2 | phosphomannomutase 2 | 0.0304189 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0301743 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0299389 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0294695 |
| TPM4 | tropomyosin 4 | 0.0294618 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0294119 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0291858 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0291316 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0290038 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0288395 |
| SIK3 | SIK family kinase 3 | 0.0288251 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0286663 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0286078 |
| DST | dystonin | 0.0284066 |
| CCNL1 | cyclin L1 | 0.028136 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0280446 |
| TMEM263 | transmembrane protein 263 | 0.0272956 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0272878 |
| YTHDC1 | YTH domain containing 1 | 0.0272181 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0271024 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0267614 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0267518 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0267355 |
| FAM13A | family with sequence similarity 13, member A | 0.0265956 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0264231 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0263854 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0263073 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.23593 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.208753 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18512 |
| TMSB10 | thymosin beta 10 | -0.0934743 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0782064 |
| TMEM165 | transmembrane protein 165 | -0.0714134 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0681343 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0616831 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.059506 |
| RPLP1 | ribosomal protein, large, P1 | -0.0594589 |
| CES1 | carboxylesterase 1 | -0.0586875 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0582456 |
| WASF2 | WAS protein family, member 2 | -0.0556049 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0549642 |
| RPS25 | ribosomal protein S25 | -0.0540604 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0502844 |
| FTL | ferritin, light polypeptide | -0.0463479 |
| PLEC | plectin | -0.0420619 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0413233 |
| RPS24 | ribosomal protein S24 | -0.0410632 |
| GRAMD1B | GRAM domain containing 1B | -0.0377126 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0376159 |
| TXNRD1 | thioredoxin reductase 1 | -0.037615 |
| WDR45B | WD repeat domain 45B | -0.0371838 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0364066 |
| ABLIM1 | actin binding LIM protein 1 | -0.0361889 |
| ANXA2 | annexin A2 | -0.0361542 |
| OSMR | oncostatin M receptor | -0.0352824 |
| TOP1 | topoisomerase (DNA) I | -0.0345611 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0343605 |
| RPS23 | ribosomal protein S23 | -0.0341303 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0337639 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0336352 |
| PKM | pyruvate kinase, muscle | -0.0329267 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0327222 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0315193 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0307267 |
| SEPTIN2 | septin 2 | -0.0304928 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0304738 |
| TPD52 | tumor protein D52 | -0.0303767 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0302818 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0299926 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0299749 |
| UVRAG | UV radiation resistance associated | -0.0298039 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0297189 |
| PDE8A | phosphodiesterase 8A | -0.029655 |
| GPC6 | glypican 6 | -0.0295287 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.029192 |
| RAB10 | RAB10, member RAS oncogene family | -0.0285922 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0280753 |
| RPL35A | ribosomal protein L35a | -0.0274705 |
| RNF145 | ring finger protein 145 | -0.0273586 |
| H1-0 | H1.0 linker histone | -0.0272267 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0270038 |
| NDRG1 | N-myc downstream regulated 1 | -0.0268991 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0268881 |
| GM2A | GM2 ganglioside activator | -0.0265177 |
| NGLY1 | N-glycanase 1 | -0.0262104 |
| PATJ | PATJ crumbs cell polarity complex component | -0.026087 |
| HMGA1 | high mobility group AT-hook 1 | -0.0260669 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259825 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0258943 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0257745 |
| RPL31 | ribosomal protein L31 | -0.0257242 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0253435 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0251049 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0250967 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0250408 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | -0.0250076 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0249816 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0246975 |
| PTMA | prothymosin, alpha | -0.0240501 |
| MGAT4C | MGAT4 family, member C | -0.0240231 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0238872 |
| TKT | transketolase | -0.0237507 |
| GNAS | GNAS complex locus | -0.023685 |
| USP34 | ubiquitin specific peptidase 34 | -0.0236168 |
| PER1 | period circadian clock 1 | -0.0235917 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0235804 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.02322 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0230495 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.0229162 |
| RPS16 | ribosomal protein S16 | -0.0228624 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0227076 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0225814 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0225489 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0224431 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0222613 |
| INTS6 | integrator complex subunit 6 | -0.0216634 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0214734 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.021469 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0211628 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0208985 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0207083 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0206813 |
| ATG14 | autophagy related 14 | -0.0205675 |
| ACTG1 | actin gamma 1 | -0.0205035 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0203875 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0202555 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0200432 |
