| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.217861 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.109279 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0867888 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0731657 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0706514 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0695902 |
| GLCCI1 | glucocorticoid induced 1 | 0.0670523 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0620128 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0618123 |
| PCBP2 | poly(rC) binding protein 2 | 0.0612709 |
| NTN4 | netrin 4 | 0.0610302 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0593213 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0569875 |
| SIK3 | SIK family kinase 3 | 0.0551614 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0550554 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0545211 |
| STK38L | serine/threonine kinase 38 like | 0.052868 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0517746 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0508559 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0486351 |
| CD44 | CD44 molecule (Indian blood group) | 0.0451767 |
| ASPH | aspartate beta-hydroxylase | 0.0447058 |
| VMP1 | vacuole membrane protein 1 | 0.0420259 |
| MYO10 | myosin X | 0.0383666 |
| IFI44L | interferon-induced protein 44-like | 0.0353495 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0350441 |
| DST | dystonin | 0.0347753 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0334056 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0330081 |
| TGM2 | transglutaminase 2 | 0.0322521 |
| NAV2 | neuron navigator 2 | 0.0320239 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0318413 |
| FAM107B | family with sequence similarity 107, member B | 0.0314988 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0314164 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0300024 |
| SMAD3 | SMAD family member 3 | 0.0298172 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0296587 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0295756 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.0294665 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0290864 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.029015 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0282683 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0278394 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0277943 |
| MSN | moesin | 0.0276007 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0271858 |
| NDRG1 | N-myc downstream regulated 1 | 0.0269778 |
| TAPBP | TAP binding protein (tapasin) | 0.0269688 |
| KSR1 | kinase suppressor of ras 1 | 0.0269541 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0268315 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0263357 |
| ATXN1 | ataxin 1 | 0.0261538 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0261044 |
| CORO1C | coronin, actin binding protein, 1C | 0.0259232 |
| BRD2 | bromodomain containing 2 | 0.0254317 |
| SEPTIN9 | septin 9 | 0.0248594 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0247178 |
| SFTPA2 | surfactant protein A2 | 0.0245019 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0244972 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0243868 |
| INTS6 | integrator complex subunit 6 | 0.0242601 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0241002 |
| IL1R1 | interleukin 1 receptor, type I | 0.0238735 |
| PRELID2 | PRELI domain containing 2 | 0.0236189 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0235981 |
| NOTCH2 | notch 2 | 0.0233196 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0233145 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0232437 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0229505 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0228598 |
| RPS12 | ribosomal protein S12 | 0.0228438 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0227947 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0226813 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0225135 |
| TOP1 | topoisomerase (DNA) I | 0.0224115 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.022283 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0221756 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0217667 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0217131 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0216641 |
| VEGFA | vascular endothelial growth factor A | 0.0215667 |
| AADAC | arylacetamide deacetylase | 0.0215168 |
| RAD51B | RAD51 paralog B | 0.0214214 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0210757 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.020867 |
| FAM3C | family with sequence similarity 3, member C | 0.0207651 |
| LAMB1 | laminin, beta 1 | 0.0206711 |
| VCL | vinculin | 0.0205451 |
| HAS2 | hyaluronan synthase 2 | 0.0205324 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0204095 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0201498 |
| BRD4 | bromodomain containing 4 | 0.0200122 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0198543 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0198155 |
| MAP1B | microtubule-associated protein 1B | 0.0197434 |
| ECE1 | endothelin converting enzyme 1 | 0.0195223 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0194208 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0191927 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.0188616 |
| RPS3 | ribosomal protein S3 | 0.0186983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.189311 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.183257 |
| VIM | vimentin | -0.138665 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.118751 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11796 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.111959 |
| NRG1 | neuregulin 1 | -0.0981012 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0963345 |
| TMSB10 | thymosin beta 10 | -0.0959018 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0954305 |
| STC1 | stanniocalcin 1 | -0.0926377 |
| FN1 | fibronectin 1 | -0.0845065 |
| IER3 | immediate early response 3 | -0.0830509 |
| RPLP1 | ribosomal protein, large, P1 | -0.0801218 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0774635 |
| CDH13 | cadherin 13 | -0.0761911 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0761335 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0726281 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0725294 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0717856 |
| OSMR | oncostatin M receptor | -0.0700569 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0679918 |
| MTSS1 | metastasis suppressor 1 | -0.0660304 |
| USP34 | ubiquitin specific peptidase 34 | -0.0646294 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0643074 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0625473 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.058291 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0576766 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0575758 |
| MEF2A | myocyte enhancer factor 2A | -0.057398 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0528021 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0504444 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0503112 |
| TMEM165 | transmembrane protein 165 | -0.0499769 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0489529 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0484899 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0480359 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0478611 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0475452 |
| LOX | lysyl oxidase | -0.047353 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0466226 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.046397 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0451208 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0449484 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0443305 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0416262 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.041105 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0406365 |
| FTL | ferritin, light polypeptide | -0.0402712 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0388079 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0381921 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0379692 |
| DNER | delta/notch-like EGF repeat containing | -0.0377197 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0375679 |
| IL1B | interleukin 1, beta | -0.0375555 |
| ENOSF1 | enolase superfamily member 1 | -0.0373938 |
| AOPEP | aminopeptidase O (putative) | -0.0370479 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0368979 |
| RPS24 | ribosomal protein S24 | -0.0367002 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0365551 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.036333 |
| RUNX2 | runt-related transcription factor 2 | -0.0357378 |
| S100A6 | S100 calcium binding protein A6 | -0.035724 |
| PYGL | phosphorylase, glycogen, liver | -0.0356859 |
| EREG | epiregulin | -0.0355483 |
| PTMA | prothymosin, alpha | -0.0353723 |
| PGK1 | phosphoglycerate kinase 1 | -0.0353329 |
| GNAS | GNAS complex locus | -0.035273 |
| VRK2 | vaccinia related kinase 2 | -0.0351966 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0351179 |
| CALU | calumenin | -0.034807 |
| DENND4A | DENN/MADD domain containing 4A | -0.034214 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0339243 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0339228 |
| EGR1 | early growth response 1 | -0.0338919 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0338651 |
| ETV6 | ets variant 6 | -0.0337358 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0332841 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0329564 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0329277 |
| ANXA2 | annexin A2 | -0.0328665 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.032584 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0325101 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0322459 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0317098 |
| CA12 | carbonic anhydrase XII | -0.0315538 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0314689 |
| FDPS | farnesyl diphosphate synthase | -0.0313962 |
| WDR45B | WD repeat domain 45B | -0.0311043 |
| CP | ceruloplasmin (ferroxidase) | -0.0310829 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0303589 |
| SPAG9 | sperm associated antigen 9 | -0.0295352 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0295295 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0294732 |
| INSIG1 | insulin induced gene 1 | -0.0294517 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0294443 |
| GRB10 | growth factor receptor-bound protein 10 | -0.02944 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0293616 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0289181 |
| FBN1 | fibrillin 1 | -0.0285449 |
