| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.189276 |
| GRAMD1B | GRAM domain containing 1B | 0.168535 |
| PM20D1 | peptidase M20 domain containing 1 | 0.134525 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0975032 |
| FAM107B | family with sequence similarity 107, member B | 0.0872398 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0693571 |
| ASPH | aspartate beta-hydroxylase | 0.0646717 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0614122 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0591001 |
| BRD2 | bromodomain containing 2 | 0.0540508 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0527041 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0507374 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0497975 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0479621 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0475158 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.047315 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0466803 |
| TPM3 | tropomyosin 3 | 0.0454231 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0446923 |
| WWOX | WW domain containing oxidoreductase | 0.0443046 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0429005 |
| MCL1 | myeloid cell leukemia 1 | 0.042302 |
| TOP1 | topoisomerase (DNA) I | 0.0414655 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0392537 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0392085 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0387871 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0367318 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0366701 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0357976 |
| RPS3 | ribosomal protein S3 | 0.0352945 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0349262 |
| KIF5B | kinesin family member 5B | 0.0341908 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0341122 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0337139 |
| WDR43 | WD repeat domain 43 | 0.0330361 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.032348 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0316886 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0313293 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0313183 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0308221 |
| MSN | moesin | 0.0303854 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292285 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0284651 |
| RPS2 | ribosomal protein S2 | 0.0279917 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0271256 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0271153 |
| TPR | translocated promoter region, nuclear basket protein | 0.0267286 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0259709 |
| BRD4 | bromodomain containing 4 | 0.0253401 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0250576 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0247607 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0247022 |
| CUL3 | cullin 3 | 0.0246734 |
| MT2A | metallothionein 2A | 0.0237829 |
| PNN | pinin, desmosome associated protein | 0.0236598 |
| EGR1 | early growth response 1 | 0.0236239 |
| VMP1 | vacuole membrane protein 1 | 0.0235342 |
| CCNL1 | cyclin L1 | 0.0235094 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0235023 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0232681 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0231803 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0231218 |
| NCKAP1 | NCK-associated protein 1 | 0.0225682 |
| KYNU | kynureninase | 0.0224847 |
| PDE10A | phosphodiesterase 10A | 0.022405 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0222502 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0222379 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0222148 |
| CENPF | centromere protein F, 350/400kDa | 0.0221659 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0221528 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0221283 |
| RPS21 | ribosomal protein S21 | 0.0218233 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0217509 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0216262 |
| MKI67 | marker of proliferation Ki-67 | 0.0216003 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0215904 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0214714 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0214076 |
| RRM2 | ribonucleotide reductase M2 | 0.0213391 |
| LAMC2 | laminin, gamma 2 | 0.0213219 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0212125 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0210909 |
| BMP6 | bone morphogenetic protein 6 | 0.0207855 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.020778 |
| HSPA4 | heat shock 70kDa protein 4 | 0.020772 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0207109 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0206285 |
| YBX3 | Y box binding protein 3 | 0.0205111 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0204682 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.020396 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0201392 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0199761 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0199029 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0198827 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0198808 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0198462 |
| RPS6 | ribosomal protein S6 | 0.019741 |
| RPS8 | ribosomal protein S8 | 0.0195908 |
| H1-2 | H1.2 linker histone, cluster member | 0.019512 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0194847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.291083 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.270439 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.202679 |
| VIM | vimentin | -0.16313 |
| IGF2 | insulin-like growth factor 2 | -0.15817 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.146121 |
| TMSB10 | thymosin beta 10 | -0.106225 |
| FTL | ferritin, light polypeptide | -0.105578 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0807206 |
| S100A6 | S100 calcium binding protein A6 | -0.0775185 |
| IER3 | immediate early response 3 | -0.0668746 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0641118 |
| PYGL | phosphorylase, glycogen, liver | -0.0639596 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0604212 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0583944 |
| RPLP1 | ribosomal protein, large, P1 | -0.0556917 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0539461 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.051104 |
| S100A10 | S100 calcium binding protein A10 | -0.0486942 |
| PKM | pyruvate kinase, muscle | -0.0457806 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0412235 |
| ZNF207 | zinc finger protein 207 | -0.0399311 |
| EGFR | epidermal growth factor receptor | -0.0392298 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0372861 |
| RPS25 | ribosomal protein S25 | -0.036594 |
| ACTG1 | actin gamma 1 | -0.0355596 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0355577 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0355358 |
| TPM4 | tropomyosin 4 | -0.0353575 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0352522 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0346254 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.034502 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0327052 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0323684 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0315102 |
| ERBIN | erbb2 interacting protein | -0.031392 |
| RPS16 | ribosomal protein S16 | -0.0312227 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0306387 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0303603 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0299713 |
| LDHA | lactate dehydrogenase A | -0.0298837 |
| HMGA1 | high mobility group AT-hook 1 | -0.0296776 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0290147 |
| USP34 | ubiquitin specific peptidase 34 | -0.0289113 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.02888 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0288577 |
| DENND4A | DENN/MADD domain containing 4A | -0.0277596 |
| RPLP0 | ribosomal protein, large, P0 | -0.0271049 |
| RPS20 | ribosomal protein S20 | -0.0267362 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0266501 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0264462 |
| IL6 | interleukin 6 | -0.0263081 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0262736 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0254895 |
| TMEM123 | transmembrane protein 123 | -0.0251747 |
| RPL39 | ribosomal protein L39 | -0.0250955 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0248656 |
| CFDP1 | craniofacial development protein 1 | -0.0247534 |
| RPL19 | ribosomal protein L19 | -0.0246791 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0246251 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0244315 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0242178 |
| TPD52 | tumor protein D52 | -0.0241827 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0239777 |
| GNAS | GNAS complex locus | -0.0239231 |
| RPS5 | ribosomal protein S5 | -0.0239218 |
| AK1 | adenylate kinase 1 | -0.0237638 |
| RPL31 | ribosomal protein L31 | -0.0237067 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0234679 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0230654 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0230642 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.023042 |
| RPS24 | ribosomal protein S24 | -0.0228414 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0228407 |
| HLA-E | major histocompatibility complex, class I, E | -0.0227199 |
| FGB | fibrinogen beta chain | -0.022585 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0223932 |
| HM13 | histocompatibility (minor) 13 | -0.0221287 |
| OSMR | oncostatin M receptor | -0.021851 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0218058 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0217517 |
| PRR16 | proline rich 16 | -0.0216243 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0215 |
| RHOA | ras homolog family member A | -0.0213103 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0211729 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0208647 |
| ANXA2 | annexin A2 | -0.0208494 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0208327 |
| FNBP1L | formin binding protein 1-like | -0.020694 |
| RLF | rearranged L-myc fusion | -0.020458 |
| NEGR1 | neuronal growth regulator 1 | -0.0204532 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.020356 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0202954 |
| BICC1 | BicC family RNA binding protein 1 | -0.0202841 |
| SRP54 | signal recognition particle 54kDa | -0.0202837 |
| RPS15 | ribosomal protein S15 | -0.0201295 |
| HLA-B | major histocompatibility complex, class I, B | -0.0199369 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0199082 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.019764 |
| SBF2 | SET binding factor 2 | -0.0195993 |
