| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.178542 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.139086 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.124781 |
| MYO5B | myosin VB | 0.102334 |
| ASPH | aspartate beta-hydroxylase | 0.0870586 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0860639 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0820436 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0812553 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0802701 |
| KYNU | kynureninase | 0.0781717 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0772786 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0726213 |
| LMO7 | LIM domain 7 | 0.07095 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0701047 |
| KRT17 | keratin 17, type I | 0.0697215 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0690226 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0650678 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0645308 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0635683 |
| VMP1 | vacuole membrane protein 1 | 0.0596437 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0593215 |
| PRELID2 | PRELI domain containing 2 | 0.0573278 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0567996 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.0566783 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0559488 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0555477 |
| VIM | vimentin | 0.0548669 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0547633 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0534239 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0531095 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0513308 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0512926 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0512003 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0510197 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0509906 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0509281 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0503024 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0498428 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0496216 |
| NBAS | neuroblastoma amplified sequence | 0.0495777 |
| FMN1 | formin 1 | 0.0495648 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0488989 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0487965 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0485594 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0479906 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0478953 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0475587 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.047104 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0467653 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.046751 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0465789 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0464942 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0445623 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0442937 |
| MT2A | metallothionein 2A | 0.044252 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0434752 |
| NAV1 | neuron navigator 1 | 0.0423451 |
| TUT7 | terminal uridylyl transferase 7 | 0.0421809 |
| TOP1 | topoisomerase (DNA) I | 0.0421109 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0417442 |
| LAMC2 | laminin, gamma 2 | 0.0417102 |
| NDRG1 | N-myc downstream regulated 1 | 0.0414106 |
| MUC16 | mucin 16, cell surface associated | 0.0408869 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0408622 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0404523 |
| AFDN | afadin, adherens junction formation factor | 0.0403784 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0403186 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0401266 |
| DUSP10 | dual specificity phosphatase 10 | 0.0393335 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0391783 |
| MYO1E | myosin IE | 0.0391303 |
| CALR | calreticulin | 0.0390777 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0390747 |
| UTRN | utrophin | 0.0390223 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.038942 |
| ANXA1 | annexin A1 | 0.0389306 |
| SON | SON DNA binding protein | 0.0387775 |
| RND3 | Rho family GTPase 3 | 0.0378952 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0366632 |
| ATP11A | ATPase, class VI, type 11A | 0.0366316 |
| CEP350 | centrosomal protein 350kDa | 0.036569 |
| GLCCI1 | glucocorticoid induced 1 | 0.036481 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0364428 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0362662 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0361835 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0356121 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.035485 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.034984 |
| OSMR | oncostatin M receptor | 0.0342577 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0340761 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0337101 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0337064 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0335023 |
| UBC | ubiquitin C | 0.0334 |
| LAMA4 | laminin, alpha 4 | 0.0329757 |
| SMAD3 | SMAD family member 3 | 0.0329482 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0328268 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0327286 |
| ENO1 | enolase 1, (alpha) | 0.0326285 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0322884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| JMJD1C | jumonji domain containing 1C | -0.0879346 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0752817 |
| NAV2 | neuron navigator 2 | -0.0742095 |
| IGF2 | insulin-like growth factor 2 | -0.0741142 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0710002 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0597356 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0592024 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0584966 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0578744 |
| ZNF292 | zinc finger protein 292 | -0.0568062 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0563158 |
| AHNAK | AHNAK nucleoprotein | -0.056157 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0560397 |
| ACTG1 | actin gamma 1 | -0.0540362 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0524837 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0520489 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0507458 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0482613 |
| OGA | O-GlcNAcase | -0.0478233 |
| RBM39 | RNA binding motif protein 39 | -0.0477583 |
| FMNL2 | formin-like 2 | -0.0477019 |
| ARF4 | ADP-ribosylation factor 4 | -0.0471006 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0456944 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0456006 |
| GNAS | GNAS complex locus | -0.0455653 |
| SQSTM1 | sequestosome 1 | -0.0450661 |
| PDE10A | phosphodiesterase 10A | -0.044413 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0438952 |
| ZNF638 | zinc finger protein 638 | -0.0436848 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0436427 |
| NBEA | neurobeachin | -0.0433857 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0428144 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0424855 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0421788 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0421405 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0411302 |
| PAPOLA | poly(A) polymerase alpha | -0.0409837 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0408113 |
| SEPTIN2 | septin 2 | -0.0403891 |
| HPCAL1 | hippocalcin-like 1 | -0.0400619 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0397784 |
| HOMER1 | homer scaffolding protein 1 | -0.0396978 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0393347 |
| STK24 | serine/threonine kinase 24 | -0.0391617 |
| SNX14 | sorting nexin 14 | -0.0387493 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0382707 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0382479 |
| CFDP1 | craniofacial development protein 1 | -0.0380617 |
| PRKCA | protein kinase C, alpha | -0.0379663 |
| SARNP | SAP domain containing ribonucleoprotein | -0.0379239 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0378695 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0375783 |
| SETD2 | SET domain containing 2 | -0.0375383 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0374968 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0372806 |
| RORA | RAR-related orphan receptor A | -0.0370796 |
| FAM13A | family with sequence similarity 13, member A | -0.0369881 |
| HDAC9 | histone deacetylase 9 | -0.0368912 |
| DENND4A | DENN/MADD domain containing 4A | -0.0367954 |
| LEMD3 | LEM domain containing 3 | -0.0365009 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.036418 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0362532 |
| TULP4 | tubby like protein 4 | -0.0360369 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0360259 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0359495 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0359215 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0358789 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0358125 |
| EGFR | epidermal growth factor receptor | -0.0357831 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0356073 |
| USP3 | ubiquitin specific peptidase 3 | -0.0354469 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0354285 |
| TXNRD1 | thioredoxin reductase 1 | -0.035019 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0349927 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0343885 |
| YME1L1 | YME1-like 1 ATPase | -0.034334 |
| SP100 | SP100 nuclear antigen | -0.0343027 |
| CLMP | CXADR-like membrane protein | -0.0342594 |
| ZNF207 | zinc finger protein 207 | -0.0342024 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0341731 |
| CADM1 | cell adhesion molecule 1 | -0.0340354 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0340246 |
| NGLY1 | N-glycanase 1 | -0.0339825 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0336973 |
| RLIM | ring finger protein, LIM domain interacting | -0.033152 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0330839 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0326748 |
| HMGXB3 | HMG box domain containing 3 | -0.032446 |
| ZNF609 | zinc finger protein 609 | -0.0322605 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0321952 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0321944 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0320865 |
| MSI2 | musashi RNA-binding protein 2 | -0.0320585 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0318748 |
| USP36 | ubiquitin specific peptidase 36 | -0.0318002 |
| TUSC3 | tumor suppressor candidate 3 | -0.0317744 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0317206 |
| TXNIP | thioredoxin interacting protein | -0.031612 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0315455 |
| MALT1 | MALT1 paracaspase | -0.0314019 |
