| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.167464 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.137554 |
| LAMB3 | laminin, beta 3 | 0.127518 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.1139 |
| LAMC2 | laminin, gamma 2 | 0.103611 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.101441 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0948525 |
| TMF1 | TATA element modulatory factor 1 | 0.0907393 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0900776 |
| RPS3 | ribosomal protein S3 | 0.086843 |
| RBM25 | RNA binding motif protein 25 | 0.0816874 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0813342 |
| DSPP | dentin sialophosphoprotein | 0.0730348 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0700604 |
| FTL | ferritin, light polypeptide | 0.0694262 |
| MSN | moesin | 0.0690803 |
| TPM3 | tropomyosin 3 | 0.0689912 |
| CTSB | cathepsin B | 0.0685117 |
| GOLGA4 | golgin A4 | 0.0671413 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.061101 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0609585 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0607991 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0588794 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0573537 |
| EZR | ezrin | 0.0568577 |
| LMO7 | LIM domain 7 | 0.0556823 |
| GOLGB1 | golgin B1 | 0.05415 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0533237 |
| RPL14 | ribosomal protein L14 | 0.0506075 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0504617 |
| RPS6 | ribosomal protein S6 | 0.0486698 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0480232 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0479429 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0471748 |
| TPR | translocated promoter region, nuclear basket protein | 0.0470145 |
| BRD2 | bromodomain containing 2 | 0.0469882 |
| RPS2 | ribosomal protein S2 | 0.0468361 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0465877 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0459747 |
| TAPBP | TAP binding protein (tapasin) | 0.045181 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0449092 |
| SDC4 | syndecan 4 | 0.0447771 |
| RND3 | Rho family GTPase 3 | 0.0446832 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0442866 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0439567 |
| RPS12 | ribosomal protein S12 | 0.0431965 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0426095 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0418772 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0416501 |
| ARRDC3 | arrestin domain containing 3 | 0.041102 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0404675 |
| HMGB2 | high mobility group box 2 | 0.0397698 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0391584 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0388947 |
| MT2A | metallothionein 2A | 0.0388304 |
| RBM39 | RNA binding motif protein 39 | 0.0386046 |
| SET | SET nuclear proto-oncogene | 0.0380916 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0379262 |
| PNN | pinin, desmosome associated protein | 0.0378432 |
| TXNIP | thioredoxin interacting protein | 0.0370246 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0365051 |
| YTHDC1 | YTH domain containing 1 | 0.0360749 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0357342 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0354581 |
| VGLL3 | vestigial-like family member 3 | 0.0353468 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0352767 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0351985 |
| CENPF | centromere protein F, 350/400kDa | 0.0350937 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0349588 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0345912 |
| FAM107B | family with sequence similarity 107, member B | 0.0345685 |
| PTMA | prothymosin, alpha | 0.0344223 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0342053 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0339505 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0335431 |
| KIF5B | kinesin family member 5B | 0.0335314 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0327858 |
| RPS8 | ribosomal protein S8 | 0.0323456 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0322395 |
| VMP1 | vacuole membrane protein 1 | 0.0319723 |
| ANXA1 | annexin A1 | 0.031796 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0315574 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0315382 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0312882 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0306442 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0303628 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0301963 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0288756 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0285751 |
| ZNF148 | zinc finger protein 148 | 0.0285343 |
| SERINC1 | serine incorporator 1 | 0.0285255 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0283179 |
| DUSP10 | dual specificity phosphatase 10 | 0.0281416 |
| YBX3 | Y box binding protein 3 | 0.0280538 |
| DST | dystonin | 0.0280394 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278734 |
| CTSS | cathepsin S | 0.0272573 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.027032 |
| TMEM263 | transmembrane protein 263 | 0.0267927 |
| AFDN | afadin, adherens junction formation factor | 0.0265301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.229176 |
| FN1 | fibronectin 1 | -0.150275 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.111074 |
| HMGA1 | high mobility group AT-hook 1 | -0.104909 |
| TMSB10 | thymosin beta 10 | -0.0991108 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0955533 |
| S100A6 | S100 calcium binding protein A6 | -0.0811282 |
| CCND1 | cyclin D1 | -0.0773839 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0756646 |
| RPLP1 | ribosomal protein, large, P1 | -0.0648832 |
| GNAS | GNAS complex locus | -0.0623948 |
| ARF1 | ADP-ribosylation factor 1 | -0.0541617 |
| TMEM123 | transmembrane protein 123 | -0.0540418 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0531131 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0531089 |
| S100A10 | S100 calcium binding protein A10 | -0.0520674 |
| PKM | pyruvate kinase, muscle | -0.0519389 |
| KRT7 | keratin 7, type II | -0.0486095 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0478903 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0472793 |
| CTSD | cathepsin D | -0.0457114 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0449813 |
| PLAU | plasminogen activator, urokinase | -0.0425272 |
| RPS24 | ribosomal protein S24 | -0.0418021 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0414448 |
| RPLP0 | ribosomal protein, large, P0 | -0.0413211 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0396848 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0384999 |
| TKT | transketolase | -0.0379224 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0378958 |
| RPS25 | ribosomal protein S25 | -0.0378448 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0377398 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0377189 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0367925 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0366942 |
| ACTG1 | actin gamma 1 | -0.0362795 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0357577 |
| RPL8 | ribosomal protein L8 | -0.035412 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0331791 |
| MXD1 | MAX dimerization protein 1 | -0.0324983 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0322379 |
| FBXO34 | F-box protein 34 | -0.0317539 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0314316 |
| RPL27A | ribosomal protein L27a | -0.0310006 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.030913 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0307649 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0306265 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0306146 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0305695 |
| ANXA2 | annexin A2 | -0.0302004 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0301307 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0298582 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0294099 |
| RNF213 | ring finger protein 213 | -0.0293664 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0293627 |
| PGK1 | phosphoglycerate kinase 1 | -0.0280925 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0279712 |
| RHOA | ras homolog family member A | -0.0279218 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0275817 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0270727 |
| LDHA | lactate dehydrogenase A | -0.0268727 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0268407 |
| ZNF207 | zinc finger protein 207 | -0.0265399 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0260224 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0258601 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.02567 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0256443 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0254237 |
| WASF2 | WAS protein family, member 2 | -0.0253129 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0251468 |
| RPL28 | ribosomal protein L28 | -0.0251171 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0250889 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0250162 |
| RPS23 | ribosomal protein S23 | -0.0243002 |
| RPS5 | ribosomal protein S5 | -0.0236199 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0235977 |
| NAV2 | neuron navigator 2 | -0.0235872 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.023515 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0233554 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0233447 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0227452 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0227373 |
| UBC | ubiquitin C | -0.0226893 |
| SEC24D | SEC24 family member D | -0.0224747 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0222202 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.022175 |
| QKI | QKI, KH domain containing, RNA binding | -0.0221375 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0221334 |
| RPL30 | ribosomal protein L30 | -0.0220906 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0219977 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.02186 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0217404 |
| CD2AP | CD2-associated protein | -0.0216102 |
| RPS20 | ribosomal protein S20 | -0.0215992 |
| RPS16 | ribosomal protein S16 | -0.0213006 |
| RPS15 | ribosomal protein S15 | -0.0212379 |
| FLNC | filamin C, gamma | -0.0211601 |
| IRF9 | interferon regulatory factor 9 | -0.0210576 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0209365 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0208674 |
