| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.183604 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.179198 |
| COL5A2 | collagen, type V, alpha 2 | 0.137168 |
| DST | dystonin | 0.129553 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0981975 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0799571 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0766277 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0740866 |
| RPS3 | ribosomal protein S3 | 0.0738758 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0732303 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0687527 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0685094 |
| INHBA | inhibin, beta A | 0.0640588 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0639434 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0625016 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0606317 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0598579 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0590793 |
| FMNL2 | formin-like 2 | 0.0568528 |
| PTMA | prothymosin, alpha | 0.0565601 |
| RGS2 | regulator of G-protein signaling 2 | 0.0555871 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0543676 |
| TMSB10 | thymosin beta 10 | 0.0543084 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0535778 |
| KYNU | kynureninase | 0.0489609 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0489603 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0480792 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0464915 |
| RPS4X | ribosomal protein S4, X-linked | 0.0462815 |
| EZR | ezrin | 0.0459774 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0447461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0435718 |
| AHNAK | AHNAK nucleoprotein | 0.0434478 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0431908 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0414564 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0413274 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0410595 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0410069 |
| RPS6 | ribosomal protein S6 | 0.0395854 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.039019 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.038362 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0374032 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0366372 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0358451 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0353019 |
| CTBP2 | C-terminal binding protein 2 | 0.0341908 |
| RPL14 | ribosomal protein L14 | 0.03249 |
| MAP7 | microtubule-associated protein 7 | 0.0324472 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0309219 |
| RPS21 | ribosomal protein S21 | 0.0305408 |
| FAM107B | family with sequence similarity 107, member B | 0.0302914 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0302844 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0302569 |
| RPL34 | ribosomal protein L34 | 0.0299382 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0294189 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0293383 |
| PDE10A | phosphodiesterase 10A | 0.0283936 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0283688 |
| RPL26 | ribosomal protein L26 | 0.0282979 |
| DNER | delta/notch-like EGF repeat containing | 0.0278962 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0278492 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.027391 |
| SFTPA2 | surfactant protein A2 | 0.0273504 |
| RPL12 | ribosomal protein L12 | 0.0268344 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0262531 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.025707 |
| RPL35A | ribosomal protein L35a | 0.0251399 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0251319 |
| TOP1 | topoisomerase (DNA) I | 0.0249883 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0246794 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0244211 |
| PRELID2 | PRELI domain containing 2 | 0.0243727 |
| MYO10 | myosin X | 0.024325 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0239313 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0238734 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0237442 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.0236224 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0235582 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0234478 |
| KLF6 | Kruppel-like factor 6 | 0.0231618 |
| RIGI | RNA sensor RIG-I | 0.0231507 |
| ANXA1 | annexin A1 | 0.0227019 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0226747 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0226274 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0225312 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0220075 |
| TENM2 | teneurin transmembrane protein 2 | 0.0219231 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0217249 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0215481 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.021092 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0210598 |
| RPS19 | ribosomal protein S19 | 0.02084 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0208284 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0206971 |
| LMO7 | LIM domain 7 | 0.020523 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0204813 |
| RPS27A | ribosomal protein S27a | 0.0204335 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.020394 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0202573 |
| BRD4 | bromodomain containing 4 | 0.0202274 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161017 |
| EFNA5 | ephrin-A5 | -0.134961 |
| FN1 | fibronectin 1 | -0.0983716 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0876584 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0680589 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.064945 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0643075 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0634428 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0631367 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0606587 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0601468 |
| MCL1 | myeloid cell leukemia 1 | -0.0528893 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0528593 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0513383 |
| AUTS2 | autism susceptibility candidate 2 | -0.0501906 |
| VIM | vimentin | -0.0489668 |
| NRCAM | neuronal cell adhesion molecule | -0.0481157 |
| MFF | mitochondrial fission factor | -0.0449002 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0439159 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.04389 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0418362 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0410375 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0407012 |
| USP34 | ubiquitin specific peptidase 34 | -0.0392417 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0390756 |
| PKM | pyruvate kinase, muscle | -0.039067 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0382664 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0376825 |
| PYGL | phosphorylase, glycogen, liver | -0.0375373 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0366467 |
| NDRG1 | N-myc downstream regulated 1 | -0.0346956 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0343245 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0336457 |
| RPS2 | ribosomal protein S2 | -0.0333065 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0321406 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0314743 |
| MYOF | myoferlin | -0.0313214 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0311649 |
| TXNRD1 | thioredoxin reductase 1 | -0.0301803 |
| NCKAP5 | NCK-associated protein 5 | -0.0301473 |
| CDH13 | cadherin 13 | -0.0294829 |
| SBF2 | SET binding factor 2 | -0.0290216 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0280417 |
| CADM2 | cell adhesion molecule 2 | -0.0277435 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0272336 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0272271 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0272216 |
| CTSC | cathepsin C | -0.0261374 |
| BPNT2 | 3'(2'), 5'-bisphosphate nucleotidase 2 | -0.0261163 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0258074 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0256498 |
| ZNF207 | zinc finger protein 207 | -0.0256198 |
| RPL39 | ribosomal protein L39 | -0.0252117 |
| RPS23 | ribosomal protein S23 | -0.0251065 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0246094 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0245726 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0239093 |
| VCL | vinculin | -0.0238786 |
| GALNT15 | polypeptide N-acetylgalactosaminyltransferase 15 | -0.0238321 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0236195 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0234094 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0232371 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0224438 |
| RPL3 | ribosomal protein L3 | -0.0223967 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0223319 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0223133 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0221448 |
| DIAPH2 | diaphanous-related formin 2 | -0.022009 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0219318 |
| LAMA5 | laminin, alpha 5 | -0.0218932 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0218242 |
| RPS25 | ribosomal protein S25 | -0.0218234 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0216226 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0212386 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0209512 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0206113 |
| NBEAL1 | neurobeachin-like 1 | -0.0205892 |
| RPL7A | ribosomal protein L7a | -0.0205165 |
| NUP58 | nucleoporin 58 | -0.0202946 |
| GLIS3 | GLIS family zinc finger 3 | -0.0202472 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0200788 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0200324 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0198995 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0198588 |
| PTGR1 | prostaglandin reductase 1 | -0.0198004 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0196432 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0196041 |
| STC1 | stanniocalcin 1 | -0.0194537 |
| ANTXR1 | anthrax toxin receptor 1 | -0.019257 |
| TOB1 | transducer of ERBB2, 1 | -0.0191849 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0189624 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0188389 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.01878 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0187541 |
| TENM3 | teneurin transmembrane protein 3 | -0.0186877 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0186304 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0182508 |
| RTN4 | reticulon 4 | -0.0182413 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0181 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0180459 |
