| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCLO | piccolo presynaptic cytomatrix protein | 0.115533 |
| DST | dystonin | 0.107726 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0948067 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0757248 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0745194 |
| COL3A1 | collagen, type III, alpha 1 | 0.0637977 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.061321 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0603894 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0591886 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0529091 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0504574 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0503103 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0502523 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0472754 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0442297 |
| XPO1 | exportin 1 | 0.0436895 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0422477 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.041822 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0413573 |
| RPS2 | ribosomal protein S2 | 0.0411631 |
| SERINC1 | serine incorporator 1 | 0.0407355 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0405212 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0389906 |
| ZNF608 | zinc finger protein 608 | 0.0380096 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0366833 |
| RPS3 | ribosomal protein S3 | 0.0350699 |
| PHF3 | PHD finger protein 3 | 0.0350133 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0348262 |
| PARD3 | par-3 family cell polarity regulator | 0.0347993 |
| PUM2 | pumilio RNA-binding family member 2 | 0.034697 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0346918 |
| TMF1 | TATA element modulatory factor 1 | 0.0337289 |
| H1-4 | H1.4 linker histone, cluster member | 0.033537 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0334914 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0331838 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0328594 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0315786 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0315664 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 | 0.0310664 |
| CCNL1 | cyclin L1 | 0.0309526 |
| RBM25 | RNA binding motif protein 25 | 0.0306986 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0306977 |
| TPR | translocated promoter region, nuclear basket protein | 0.0304746 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0304318 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0304152 |
| NCKAP1 | NCK-associated protein 1 | 0.0295806 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0290674 |
| REST | RE1-silencing transcription factor | 0.0288862 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0287953 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0287401 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0286331 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0286311 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0285808 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0283999 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0282238 |
| BRD2 | bromodomain containing 2 | 0.0282101 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0278532 |
| CTPS1 | CTP synthase 1 | 0.027779 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0277011 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0271469 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0266619 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0263604 |
| NFIB | nuclear factor I/B | 0.0263365 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262009 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0259988 |
| ARRDC3 | arrestin domain containing 3 | 0.025664 |
| GPC4 | glypican 4 | 0.0256583 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0251737 |
| FGFR1OP2 | FGFR1 oncogene partner 2 | 0.0250626 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0250312 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0250149 |
| CCNG2 | cyclin G2 | 0.0247608 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.024712 |
| TPM3 | tropomyosin 3 | 0.0246236 |
| NCOA1 | nuclear receptor coactivator 1 | 0.0245626 |
| METAP2 | methionyl aminopeptidase 2 | 0.0244194 |
| RPS12 | ribosomal protein S12 | 0.0243678 |
| ABI2 | abl-interactor 2 | 0.0241936 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0241611 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0241365 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0241217 |
| OGA | O-GlcNAcase | 0.0238854 |
| CFL2 | cofilin 2 (muscle) | 0.0238174 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0236897 |
| USP53 | ubiquitin specific peptidase 53 | 0.0236567 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0234157 |
| ANK2 | ankyrin 2, neuronal | 0.023065 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.0228716 |
| FIGN | fidgetin | 0.0228558 |
| UTRN | utrophin | 0.0228085 |
| NKTR | natural killer cell triggering receptor | 0.022803 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.022685 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0226568 |
| SRP54 | signal recognition particle 54kDa | 0.0226093 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0225708 |
| RANBP9 | RAN binding protein 9 | 0.02254 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0225088 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0224946 |
| USP25 | ubiquitin specific peptidase 25 | 0.0224015 |
| TLK1 | tousled-like kinase 1 | 0.0223142 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.182796 |
| VIM | vimentin | -0.133756 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.120508 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.117824 |
| PCDH9 | protocadherin 9 | -0.0937607 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0890907 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0754053 |
| GPC3 | glypican 3 | -0.0718324 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0712809 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0709165 |
| RPS16 | ribosomal protein S16 | -0.0686165 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0647093 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0619568 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.058923 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0579753 |
| GNAS | GNAS complex locus | -0.0578887 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0563509 |
| NRG1 | neuregulin 1 | -0.0557961 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0554676 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0553095 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0549485 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0543195 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0528134 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0517291 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0515374 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0507463 |
| COL1A2 | collagen, type I, alpha 2 | -0.0504418 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.05025 |
| ACTG1 | actin gamma 1 | -0.0498096 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0496227 |
| NEBL | nebulette | -0.0475803 |
| LRRC4C | leucine rich repeat containing 4C | -0.0467737 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0467335 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0462902 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.045251 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0443862 |
| RPLP1 | ribosomal protein, large, P1 | -0.0443691 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0428227 |
| TMSB10 | thymosin beta 10 | -0.0418165 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0417595 |
| ENO1 | enolase 1, (alpha) | -0.0410935 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0403554 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0386403 |
| HMGB1 | high mobility group box 1 | -0.0386096 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0385275 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0380676 |
| ARF1 | ADP-ribosylation factor 1 | -0.0370892 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0368091 |
| ANXA2 | annexin A2 | -0.0366794 |
| NTM | neurotrimin | -0.0362061 |
| VGLL3 | vestigial-like family member 3 | -0.0355214 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0354753 |
| EMP1 | epithelial membrane protein 1 | -0.0352125 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0351859 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0351151 |
| RAD51B | RAD51 paralog B | -0.0345139 |
| FNDC3B | fibronectin type III domain containing 3B | -0.033129 |
| PGK1 | phosphoglycerate kinase 1 | -0.0328463 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0322814 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0321857 |
| MYADM | myeloid-associated differentiation marker | -0.0319723 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0315971 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0314123 |
| RPS24 | ribosomal protein S24 | -0.0308942 |
| RPL35A | ribosomal protein L35a | -0.0307434 |
| SIK2 | salt-inducible kinase 2 | -0.0303023 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0302411 |
| LDHA | lactate dehydrogenase A | -0.029994 |
| HMCN1 | hemicentin 1 | -0.0299494 |
| TUBA1B | tubulin, alpha 1b | -0.0297757 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0295819 |
| S100A10 | S100 calcium binding protein A10 | -0.0295671 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0295358 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0293244 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0291251 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0285246 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0284883 |
| RFPL4B | ret finger protein-like 4B | -0.0283771 |
| FBXO11 | F-box protein 11 | -0.0283713 |
| QKI | QKI, KH domain containing, RNA binding | -0.0283484 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0283219 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0282226 |
| RPS25 | ribosomal protein S25 | -0.0280307 |
| FTL | ferritin, light polypeptide | -0.027955 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0276916 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0274065 |
| PKM | pyruvate kinase, muscle | -0.0273668 |
| SETD5 | SET domain containing 5 | -0.0273507 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0272714 |
| ZNF292 | zinc finger protein 292 | -0.027169 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0270695 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0270516 |
| THOC2 | THO complex 2 | -0.026722 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0266317 |
| TUT4 | terminal uridylyl transferase 4 | -0.0265795 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.026261 |
| HDAC2 | histone deacetylase 2 | -0.0260463 |
| HMGA1 | high mobility group AT-hook 1 | -0.0258044 |
| DENND5A | DENN/MADD domain containing 5A | -0.0255898 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0255822 |
