| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.3588 |
| VCL | vinculin | 0.224956 |
| RPS3 | ribosomal protein S3 | 0.106154 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100447 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.100327 |
| EGR1 | early growth response 1 | 0.098327 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0929067 |
| CENPF | centromere protein F, 350/400kDa | 0.0851587 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0848564 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0755063 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0659772 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0640005 |
| JUN | jun proto-oncogene | 0.0639568 |
| ZFP36 | ZFP36 ring finger protein | 0.0624323 |
| SFTPA2 | surfactant protein A2 | 0.0616446 |
| RPS2 | ribosomal protein S2 | 0.0613735 |
| BRD2 | bromodomain containing 2 | 0.0601917 |
| RPS12 | ribosomal protein S12 | 0.0593983 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0586552 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0578022 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0572766 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0558589 |
| PTMA | prothymosin, alpha | 0.0552902 |
| RPS8 | ribosomal protein S8 | 0.0534332 |
| MCL1 | myeloid cell leukemia 1 | 0.0528706 |
| VMP1 | vacuole membrane protein 1 | 0.0513801 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0502431 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0493642 |
| MSN | moesin | 0.0490242 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0483314 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0479848 |
| MAP1B | microtubule-associated protein 1B | 0.0476959 |
| TAPBP | TAP binding protein (tapasin) | 0.0472291 |
| HDAC9 | histone deacetylase 9 | 0.04713 |
| GOLGB1 | golgin B1 | 0.0464941 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0463888 |
| ASPH | aspartate beta-hydroxylase | 0.0451728 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0450017 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0449352 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0439859 |
| MKI67 | marker of proliferation Ki-67 | 0.0438253 |
| MT2A | metallothionein 2A | 0.0430497 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0429065 |
| RPS6 | ribosomal protein S6 | 0.0411736 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0410156 |
| RPL37A | ribosomal protein L37a | 0.0404948 |
| SET | SET nuclear proto-oncogene | 0.0402094 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0398065 |
| MYO1E | myosin IE | 0.0396827 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0378585 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0374292 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0373681 |
| PCBP2 | poly(rC) binding protein 2 | 0.0363443 |
| TPM3 | tropomyosin 3 | 0.0360158 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0355721 |
| TPR | translocated promoter region, nuclear basket protein | 0.0353109 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0352597 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.034411 |
| SQSTM1 | sequestosome 1 | 0.0343051 |
| RPL26 | ribosomal protein L26 | 0.0343043 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0331911 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0330585 |
| DST | dystonin | 0.032927 |
| B2M | beta-2-microglobulin | 0.0327826 |
| KIF5B | kinesin family member 5B | 0.0325752 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0325519 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0324375 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0321641 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.031373 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.031145 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0307669 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0307572 |
| CA8 | carbonic anhydrase VIII | 0.0306475 |
| YBX1 | Y box binding protein 1 | 0.0305931 |
| ZNF146 | zinc finger protein 146 | 0.0305555 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0302293 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0298113 |
| RACK1 | receptor for activated C kinase 1 | 0.0295568 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0295458 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0295283 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0293362 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0291598 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0290615 |
| FTL | ferritin, light polypeptide | 0.0289756 |
| INTS6 | integrator complex subunit 6 | 0.0289597 |
| BRD4 | bromodomain containing 4 | 0.0289142 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0287738 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0285132 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0284762 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0278401 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.027419 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0271852 |
| RPL35A | ribosomal protein L35a | 0.0271089 |
| SLK | STE20-like kinase | 0.0266853 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0265962 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.026433 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0262909 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0258546 |
| ATF3 | activating transcription factor 3 | 0.0258447 |
| VEGFA | vascular endothelial growth factor A | 0.0257554 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | -0.168679 |
| ACTN4 | actinin, alpha 4 | -0.102968 |
| CD44 | CD44 molecule (Indian blood group) | -0.0995439 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0770544 |
| SMAD3 | SMAD family member 3 | -0.0761761 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0690223 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0652337 |
| TMEM123 | transmembrane protein 123 | -0.0645834 |
| AFAP1 | actin filament associated protein 1 | -0.0590475 |
| VIM | vimentin | -0.057861 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0576515 |
| AHNAK | AHNAK nucleoprotein | -0.0539324 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0534648 |
| TMSB10 | thymosin beta 10 | -0.0522988 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0454386 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0437333 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0415023 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0398038 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0389714 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | -0.03771 |
| MYOF | myoferlin | -0.0368042 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0349844 |
| CTSD | cathepsin D | -0.0349472 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0343815 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0342082 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0339606 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0333946 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.032894 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0327901 |
| RPS24 | ribosomal protein S24 | -0.032624 |
| MED13L | mediator complex subunit 13-like | -0.0324984 |
| CD109 | CD109 molecule | -0.0318345 |
| ANXA2 | annexin A2 | -0.0312402 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0306889 |
| PDE10A | phosphodiesterase 10A | -0.0304562 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0298711 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0295655 |
| SBF2 | SET binding factor 2 | -0.0291049 |
| FRMD5 | FERM domain containing 5 | -0.0290967 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0289878 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0289623 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0274022 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0269744 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0264243 |
| ATP13A3 | ATPase type 13A3 | -0.0263829 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0261799 |
| PYGB | phosphorylase, glycogen; brain | -0.025938 |
| SSH1 | slingshot protein phosphatase 1 | -0.0258552 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253364 |
| EGFR | epidermal growth factor receptor | -0.0252218 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0251748 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.024744 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0246361 |
| TUBB | tubulin, beta class I | -0.0241624 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0240575 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.024016 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0238868 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0238555 |
| ATG7 | autophagy related 7 | -0.023809 |
| PRSS23 | protease, serine, 23 | -0.0233489 |
| CDCP1 | CUB domain containing protein 1 | -0.0231541 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0229934 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0228081 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0223016 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0220189 |
| HM13 | histocompatibility (minor) 13 | -0.0219427 |
| BMERB1 | bMERB domain containing 1 | -0.0218948 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0218904 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.021583 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0215257 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0215018 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0209564 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0207866 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0207577 |
| GNAS | GNAS complex locus | -0.0202178 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.019713 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0194283 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0193679 |
| ZNF331 | zinc finger protein 331 | -0.0193497 |
| SEPTIN9 | septin 9 | -0.0192091 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0191614 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0190704 |
| MYO10 | myosin X | -0.0190292 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0189739 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0189227 |
| FHL2 | four and a half LIM domains 2 | -0.0186652 |
| PERP | PERP, TP53 apoptosis effector | -0.0186271 |
| BSG | basigin (Ok blood group) | -0.0185204 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0184766 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0183281 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0183104 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | -0.018115 |
| HPCAL1 | hippocalcin-like 1 | -0.0180117 |
| CDC42SE2 | CDC42 small effector 2 | -0.0179506 |
| STAT5B | signal transducer and activator of transcription 5B | -0.0178908 |
| RASAL2 | RAS protein activator like 2 | -0.0178873 |
| EFNA5 | ephrin-A5 | -0.0178723 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0178379 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0174137 |
| RPL27A | ribosomal protein L27a | -0.0173852 |
