| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.123059 |
| EZR | ezrin | 0.106498 |
| LMO7 | LIM domain 7 | 0.0904371 |
| LAMB3 | laminin, beta 3 | 0.0869045 |
| TJP1 | tight junction protein 1 | 0.0798885 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0788633 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.078211 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0747856 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0712889 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0710504 |
| GOLGB1 | golgin B1 | 0.0670736 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0661538 |
| SMAD3 | SMAD family member 3 | 0.0618988 |
| NAV2 | neuron navigator 2 | 0.0605492 |
| VMP1 | vacuole membrane protein 1 | 0.0599002 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0597051 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0583056 |
| SVIL | supervillin | 0.0529348 |
| MYO1E | myosin IE | 0.052223 |
| YBX3 | Y box binding protein 3 | 0.0521369 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0511994 |
| EFNA5 | ephrin-A5 | 0.0510144 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0504779 |
| DSPP | dentin sialophosphoprotein | 0.0503796 |
| AFDN | afadin, adherens junction formation factor | 0.0501781 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0498952 |
| AHNAK | AHNAK nucleoprotein | 0.0498838 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0496329 |
| NDRG1 | N-myc downstream regulated 1 | 0.0481186 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0478824 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0474047 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0473901 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0464594 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0457076 |
| FAM107B | family with sequence similarity 107, member B | 0.045467 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0454227 |
| ERBIN | erbb2 interacting protein | 0.0453624 |
| CD47 | CD47 molecule | 0.0452471 |
| TAPBP | TAP binding protein (tapasin) | 0.0452034 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0437362 |
| TMF1 | TATA element modulatory factor 1 | 0.0436359 |
| ATF3 | activating transcription factor 3 | 0.0435721 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0433351 |
| BRD2 | bromodomain containing 2 | 0.0428454 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0422206 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0413859 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0411595 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0408755 |
| EMP1 | epithelial membrane protein 1 | 0.0404587 |
| FMNL2 | formin-like 2 | 0.0401513 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0381545 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0381536 |
| RBM39 | RNA binding motif protein 39 | 0.0380547 |
| CLDN1 | claudin 1 | 0.0378032 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0377699 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0375048 |
| MYO5B | myosin VB | 0.0374357 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0373506 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0373263 |
| VEGFA | vascular endothelial growth factor A | 0.0369004 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0365985 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0355782 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0351056 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0346131 |
| RND3 | Rho family GTPase 3 | 0.0344011 |
| APP | amyloid beta (A4) precursor protein | 0.0342789 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0342784 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0339117 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0335962 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0333924 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0333004 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0331116 |
| ATXN1 | ataxin 1 | 0.033095 |
| MEF2A | myocyte enhancer factor 2A | 0.0330088 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0329605 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0323831 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0322262 |
| SLK | STE20-like kinase | 0.031403 |
| OXSR1 | oxidative stress responsive 1 | 0.0309244 |
| EHF | ets homologous factor | 0.0309193 |
| PLSCR1 | phospholipid scramblase 1 | 0.0308815 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0299288 |
| ANXA1 | annexin A1 | 0.0296843 |
| B2M | beta-2-microglobulin | 0.0296256 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0295588 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0292376 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0289711 |
| BRD4 | bromodomain containing 4 | 0.0289257 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0288401 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0287347 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0285017 |
| ZNF644 | zinc finger protein 644 | 0.0284437 |
| ARRDC3 | arrestin domain containing 3 | 0.0283191 |
| JUN | jun proto-oncogene | 0.0281373 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0279814 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0276116 |
| RPS3 | ribosomal protein S3 | 0.0275798 |
| ETV6 | ets variant 6 | 0.0275105 |
| FNIP1 | folliculin interacting protein 1 | 0.0274149 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.027372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205977 |
| PTMA | prothymosin, alpha | -0.115993 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106639 |
| TMSB10 | thymosin beta 10 | -0.0942387 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.093193 |
| RPL35A | ribosomal protein L35a | -0.0905599 |
| HMGA1 | high mobility group AT-hook 1 | -0.0824706 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0816729 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0795463 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0568415 |
| RPS24 | ribosomal protein S24 | -0.0559714 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0539555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0532208 |
| S100A6 | S100 calcium binding protein A6 | -0.0511743 |
| RPLP1 | ribosomal protein, large, P1 | -0.0487041 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0460343 |
| KRT7 | keratin 7, type II | -0.044335 |
| MUC4 | mucin 4, cell surface associated | -0.0438438 |
| TMEM123 | transmembrane protein 123 | -0.0429156 |
| RPL23 | ribosomal protein L23 | -0.0417144 |
| HLA-C | major histocompatibility complex, class I, C | -0.0394554 |
| KRT8 | keratin 8, type II | -0.037489 |
| RUNX1 | runt-related transcription factor 1 | -0.0366973 |
| DIAPH3 | diaphanous-related formin 3 | -0.0362721 |
| VIM | vimentin | -0.0356672 |
| CD2AP | CD2-associated protein | -0.0352404 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0351995 |
| SPAG9 | sperm associated antigen 9 | -0.0344314 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0341492 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.033728 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.033273 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0324902 |
| RPL36A | ribosomal protein L36a | -0.0323703 |
| EGR1 | early growth response 1 | -0.0318774 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0312086 |
| LAMA4 | laminin, alpha 4 | -0.0310098 |
| PLAT | plasminogen activator, tissue | -0.0308435 |
| RPS27A | ribosomal protein S27a | -0.0304028 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.030401 |
| RPS23 | ribosomal protein S23 | -0.0297712 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0293116 |
| RPL19 | ribosomal protein L19 | -0.0290194 |
| KRT18 | keratin 18, type I | -0.0288759 |
| RPS25 | ribosomal protein S25 | -0.028673 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0284831 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0282272 |
| PKM | pyruvate kinase, muscle | -0.0282249 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0282164 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.028005 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0277292 |
| RPS21 | ribosomal protein S21 | -0.0275917 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0273477 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0272182 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0271592 |
| RPS13 | ribosomal protein S13 | -0.026713 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0264182 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0262348 |
| BSG | basigin (Ok blood group) | -0.0260744 |
| ACTN4 | actinin, alpha 4 | -0.0260319 |
| S100A10 | S100 calcium binding protein A10 | -0.0253948 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0248061 |
| RPL34 | ribosomal protein L34 | -0.024597 |
| ITGB4 | integrin, beta 4 | -0.0241839 |
| GNAS | GNAS complex locus | -0.0241799 |
| RPL28 | ribosomal protein L28 | -0.0240966 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0239125 |
| LAMA5 | laminin, alpha 5 | -0.023875 |
| TOP1 | topoisomerase (DNA) I | -0.0237822 |
| FOSL1 | FOS-like antigen 1 | -0.0235034 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0234194 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0232467 |
| RPS28 | ribosomal protein S28 | -0.0231355 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0229734 |
| XPO1 | exportin 1 | -0.0229347 |
| S100A9 | S100 calcium binding protein A9 | -0.0228943 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0225235 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0222326 |
| HMGB1 | high mobility group box 1 | -0.0221206 |
| PLAC8 | placenta-specific 8 | -0.021902 |
| VCL | vinculin | -0.0217836 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0217764 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0215715 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0214537 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0213505 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0212928 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0212877 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | -0.0212829 |
| RPS19 | ribosomal protein S19 | -0.021176 |
| TC2N | tandem C2 domains, nuclear | -0.0210688 |
| GANAB | glucosidase, alpha; neutral AB | -0.020946 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.020905 |
| RACK1 | receptor for activated C kinase 1 | -0.0208837 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0208399 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.0206022 |
| RPL11 | ribosomal protein L11 | -0.0201978 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0201723 |
| CTSD | cathepsin D | -0.0201714 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0199513 |
| TNS4 | tensin 4 | -0.0198874 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0198742 |
