| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.10111 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0907784 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0821682 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0755676 |
| RPS3 | ribosomal protein S3 | 0.0740087 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0671709 |
| RPS12 | ribosomal protein S12 | 0.0641904 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0601516 |
| RPS6 | ribosomal protein S6 | 0.0580692 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0540518 |
| CAPRIN2 | caprin family member 2 | 0.0525677 |
| LAMB3 | laminin, beta 3 | 0.0481693 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0470266 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.045183 |
| CORO1C | coronin, actin binding protein, 1C | 0.0445219 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0434872 |
| SGMS2 | sphingomyelin synthase 2 | 0.0426956 |
| RPL26 | ribosomal protein L26 | 0.0426288 |
| GLRX | glutaredoxin (thioltransferase) | 0.0419431 |
| SET | SET nuclear proto-oncogene | 0.0405192 |
| TMF1 | TATA element modulatory factor 1 | 0.040307 |
| RPS2 | ribosomal protein S2 | 0.0401871 |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.0385927 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.037664 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0374038 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0373558 |
| BRD4 | bromodomain containing 4 | 0.0372486 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0368769 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0349724 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0345294 |
| SON | SON DNA binding protein | 0.0342365 |
| RPL14 | ribosomal protein L14 | 0.0341207 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0336557 |
| RPS21 | ribosomal protein S21 | 0.0335737 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0331771 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0323487 |
| MCL1 | myeloid cell leukemia 1 | 0.031676 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0307259 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0305667 |
| RCOR1 | REST corepressor 1 | 0.0304126 |
| RPS4X | ribosomal protein S4, X-linked | 0.0302269 |
| SFTPA2 | surfactant protein A2 | 0.0298155 |
| RPL34 | ribosomal protein L34 | 0.0283689 |
| FRMD6 | FERM domain containing 6 | 0.0281945 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0278995 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0274648 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0273702 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0272947 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0265791 |
| GOLGB1 | golgin B1 | 0.026503 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0263982 |
| RPL3 | ribosomal protein L3 | 0.0262671 |
| PGM3 | phosphoglucomutase 3 | 0.025312 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0249068 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0247347 |
| RBM12 | RNA binding motif protein 12 | 0.0247025 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0246126 |
| EEA1 | early endosome antigen 1 | 0.0246108 |
| RPS17 | ribosomal protein S17 | 0.0243926 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0243697 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0241848 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0240928 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0240837 |
| YBX3 | Y box binding protein 3 | 0.0237351 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0237005 |
| GOLGA4 | golgin A4 | 0.0236836 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0236521 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0230433 |
| NUDC | nudC nuclear distribution protein | 0.0228397 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0227993 |
| CMIP | c-Maf inducing protein | 0.0227398 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0222367 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0220176 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0219969 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0219777 |
| CUL3 | cullin 3 | 0.021909 |
| ATF4 | activating transcription factor 4 | 0.0216333 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.021618 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0215685 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0215109 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0214848 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0213334 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0210671 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.021055 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0209484 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0206379 |
| ADTRP | androgen-dependent TFPI-regulating protein | 0.0202985 |
| RPL18 | ribosomal protein L18 | 0.0202736 |
| DST | dystonin | 0.0200816 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0200007 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0199905 |
| SATB2 | SATB homeobox 2 | 0.0199068 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0198147 |
| RPL12 | ribosomal protein L12 | 0.0196764 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0196712 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0196391 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.019599 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.019569 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0195226 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0194412 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.216364 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.200508 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.108829 |
| TTR | transthyretin | -0.102468 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100407 |
| RPLP1 | ribosomal protein, large, P1 | -0.0983174 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0957305 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0879977 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0807315 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.075178 |
| BNC2 | basonuclin 2 | -0.0697261 |
| DIAPH3 | diaphanous-related formin 3 | -0.0672397 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0622625 |
| ZNF438 | zinc finger protein 438 | -0.0583075 |
| PTK2 | protein tyrosine kinase 2 | -0.0552552 |
| RPL7A | ribosomal protein L7a | -0.0507696 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0502122 |
| RPS25 | ribosomal protein S25 | -0.0501504 |
| TPM4 | tropomyosin 4 | -0.047144 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0467307 |
| ANXA2 | annexin A2 | -0.0454482 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0452047 |
| RAB3IP | RAB3A interacting protein | -0.0446687 |
| ZNF292 | zinc finger protein 292 | -0.0444138 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0414176 |
| STC1 | stanniocalcin 1 | -0.0408823 |
| MTAP | methylthioadenosine phosphorylase | -0.0405148 |
| FLNB | filamin B, beta | -0.0401044 |
| USP3 | ubiquitin specific peptidase 3 | -0.0398601 |
| OLA1 | Obg-like ATPase 1 | -0.0396351 |
| RPS20 | ribosomal protein S20 | -0.0396208 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0395221 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0395154 |
| RLF | rearranged L-myc fusion | -0.0387312 |
| SBF2 | SET binding factor 2 | -0.0385661 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.038237 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0381481 |
| RPS24 | ribosomal protein S24 | -0.0375919 |
| TPD52 | tumor protein D52 | -0.0374703 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0370317 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0364075 |
| BBX | bobby sox homolog (Drosophila) | -0.0359596 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0359426 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0358239 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.034662 |
| HMGA1 | high mobility group AT-hook 1 | -0.0345619 |
| RPS16 | ribosomal protein S16 | -0.0344988 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0341858 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0341406 |
| CANX | calnexin | -0.0338103 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0337186 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0336117 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.033527 |
| C1ORF52 | chromosome 1 open reading frame 52 | -0.0333724 |
| NF1 | neurofibromin 1 | -0.0332743 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0329689 |
| GNAS | GNAS complex locus | -0.032656 |
| NUP58 | nucleoporin 58 | -0.0325914 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0325093 |
| PKM | pyruvate kinase, muscle | -0.0324244 |
| UPP1 | uridine phosphorylase 1 | -0.0320393 |
| WDR45B | WD repeat domain 45B | -0.0316623 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.031309 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0312876 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0311013 |
| NABP1 | nucleic acid binding protein 1 | -0.0310098 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0306926 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0298028 |
| FRMD4A | FERM domain containing 4A | -0.0296954 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0294163 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0290915 |
| ACTG1 | actin gamma 1 | -0.0288008 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0287436 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0287082 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0287056 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0286328 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0285786 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0285741 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0284201 |
| FOXO3 | forkhead box O3 | -0.0280716 |
| NAV3 | neuron navigator 3 | -0.0280631 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0280465 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0278234 |
| RUNX1 | runt-related transcription factor 1 | -0.027575 |
| RPL27A | ribosomal protein L27a | -0.0275075 |
| USP34 | ubiquitin specific peptidase 34 | -0.0271575 |
| TMEM123 | transmembrane protein 123 | -0.0270576 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0267604 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0265703 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0261047 |
| RPS29 | ribosomal protein S29 | -0.025618 |
| LDHB | lactate dehydrogenase B | -0.0255626 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0254977 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.025423 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0253924 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0253844 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0247091 |
| RPL8 | ribosomal protein L8 | -0.0243741 |
| ARFGEF3 | ARFGEF family member 3 | -0.0242396 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.023988 |
