| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0854876 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0803854 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0767638 |
| SMAD3 | SMAD family member 3 | 0.07538 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0663683 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0645966 |
| VEGFA | vascular endothelial growth factor A | 0.0633141 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0626849 |
| CD44 | CD44 molecule (Indian blood group) | 0.0577082 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0570861 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0562858 |
| SVIL | supervillin | 0.0544304 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0521661 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0511706 |
| ANGPTL4 | angiopoietin-like 4 | 0.0505144 |
| B2M | beta-2-microglobulin | 0.0498404 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0496345 |
| HDAC9 | histone deacetylase 9 | 0.048487 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0466818 |
| FAT1 | FAT atypical cadherin 1 | 0.0459809 |
| TOP1 | topoisomerase (DNA) I | 0.0443027 |
| HPCAL1 | hippocalcin-like 1 | 0.0438687 |
| COL5A1 | collagen, type V, alpha 1 | 0.0437353 |
| RPS6 | ribosomal protein S6 | 0.0420831 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0416478 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.04152 |
| MSN | moesin | 0.0398267 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0390978 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0385865 |
| GOLGB1 | golgin B1 | 0.0384107 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0377696 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0375546 |
| RPS3 | ribosomal protein S3 | 0.0371955 |
| RUNX1 | runt-related transcription factor 1 | 0.0368848 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.03591 |
| RPS12 | ribosomal protein S12 | 0.0356992 |
| FLNB | filamin B, beta | 0.0350527 |
| IFI44L | interferon-induced protein 44-like | 0.0335422 |
| TGM2 | transglutaminase 2 | 0.03315 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0330757 |
| STC1 | stanniocalcin 1 | 0.0329019 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0327831 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0321149 |
| COL5A3 | collagen, type V, alpha 3 | 0.0318436 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0315688 |
| TMF1 | TATA element modulatory factor 1 | 0.031355 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0302692 |
| ASPH | aspartate beta-hydroxylase | 0.0301957 |
| DSCAM | Down syndrome cell adhesion molecule | 0.029352 |
| NAV2 | neuron navigator 2 | 0.0293492 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.029066 |
| MT2A | metallothionein 2A | 0.0289431 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0288857 |
| CORO1C | coronin, actin binding protein, 1C | 0.0282191 |
| SEPTIN9 | septin 9 | 0.0270589 |
| SETBP1 | SET binding protein 1 | 0.0268402 |
| PLAT | plasminogen activator, tissue | 0.0261689 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0261352 |
| MED13L | mediator complex subunit 13-like | 0.0258713 |
| RPS17 | ribosomal protein S17 | 0.0257782 |
| VMP1 | vacuole membrane protein 1 | 0.0255226 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0252945 |
| SFTPA2 | surfactant protein A2 | 0.0252194 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0252005 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0251856 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0251172 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0250818 |
| FHIT | fragile histidine triad | 0.0249194 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0247555 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0246754 |
| SMYD3 | SET and MYND domain containing 3 | 0.0244852 |
| PCBP3 | poly(rC) binding protein 3 | 0.0244697 |
| SFPQ | splicing factor proline/glutamine-rich | 0.02412 |
| RPL23 | ribosomal protein L23 | 0.0239669 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0238778 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.023604 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.023604 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0235568 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0234063 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0233563 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0233484 |
| BRD2 | bromodomain containing 2 | 0.0233285 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0231851 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0230263 |
| H1-0 | H1.0 linker histone | 0.0229164 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0229135 |
| AFDN | afadin, adherens junction formation factor | 0.0228446 |
| FRMD4A | FERM domain containing 4A | 0.022719 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0225017 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0223547 |
| HMGA2 | high mobility group AT-hook 2 | 0.0223145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0219949 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0219915 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0219799 |
| RPS8 | ribosomal protein S8 | 0.021909 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0217398 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0216848 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0215398 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0214279 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0210414 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.311197 |
| VIM | vimentin | -0.26294 |
| COL1A1 | collagen, type I, alpha 1 | -0.132013 |
| COL1A2 | collagen, type I, alpha 2 | -0.109255 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105256 |
| NDRG1 | N-myc downstream regulated 1 | -0.0803891 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0767546 |
| CDH13 | cadherin 13 | -0.0694502 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0654037 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0652253 |
| TPM4 | tropomyosin 4 | -0.0636771 |
| MMP12 | matrix metallopeptidase 12 | -0.0618099 |
| PGK1 | phosphoglycerate kinase 1 | -0.0604122 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0599984 |
| TPM1 | tropomyosin 1 (alpha) | -0.0579399 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0537801 |
| PKM | pyruvate kinase, muscle | -0.0524367 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0503212 |
| IER3 | immediate early response 3 | -0.0465136 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0455966 |
| GNAS | GNAS complex locus | -0.0451935 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0439264 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0427757 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0413962 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0407063 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0399683 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0395934 |
| CALU | calumenin | -0.0393989 |
| TMSB10 | thymosin beta 10 | -0.0383615 |
| VCAN | versican | -0.0376604 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0374408 |
| NRP1 | neuropilin 1 | -0.0365711 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0362672 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0361807 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0350669 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0340449 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.033536 |
| POTEF | POTE ankyrin domain family, member F | -0.0331632 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.032992 |
| TNS3 | tensin 3 | -0.0326489 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0326121 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0321603 |
| HM13 | histocompatibility (minor) 13 | -0.0321252 |
| ITGA1 | integrin, alpha 1 | -0.0320411 |
| FTL | ferritin, light polypeptide | -0.0318017 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0317639 |
| CA12 | carbonic anhydrase XII | -0.0311393 |
| CD109 | CD109 molecule | -0.0311363 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0304739 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0290331 |
| LMAN1 | lectin, mannose-binding, 1 | -0.028695 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0285288 |
| HLA-C | major histocompatibility complex, class I, C | -0.0278701 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0278085 |
| TNNC1 | troponin C type 1 (slow) | -0.0277985 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0276164 |
| HLA-B | major histocompatibility complex, class I, B | -0.0275596 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0274505 |
| ZNF292 | zinc finger protein 292 | -0.0270896 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0269932 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0267241 |
| ITGA11 | integrin, alpha 11 | -0.0266838 |
| COL5A2 | collagen, type V, alpha 2 | -0.0261592 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0258147 |
| THBS1 | thrombospondin 1 | -0.0257478 |
| NREP | neuronal regeneration related protein | -0.0255442 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0248406 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0247285 |
| S100A6 | S100 calcium binding protein A6 | -0.0246957 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0237891 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0237375 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0236848 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0232292 |
| RND3 | Rho family GTPase 3 | -0.023004 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0229961 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.022945 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0224086 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0223706 |
| IL1B | interleukin 1, beta | -0.0222396 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0219259 |
| FBN1 | fibrillin 1 | -0.0218555 |
| PTGFR | prostaglandin F receptor (FP) | -0.0216917 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0216475 |
| PXDN | peroxidasin | -0.0216374 |
| RRBP1 | ribosome binding protein 1 | -0.0216293 |
| RPLP1 | ribosomal protein, large, P1 | -0.0215156 |
| SEC24D | SEC24 family member D | -0.0210193 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0209577 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0208883 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0208731 |
| INHBA | inhibin, beta A | -0.0208388 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0207729 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0206422 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0205875 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0204897 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0204636 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0204462 |
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | -0.0203482 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.0198637 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0197593 |
