| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0646292 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0635721 |
| VGF | VGF nerve growth factor inducible | 0.0616085 |
| INHBA | inhibin, beta A | 0.0599704 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0593147 |
| PDE10A | phosphodiesterase 10A | 0.0549621 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0500573 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0491927 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0480383 |
| MCL1 | myeloid cell leukemia 1 | 0.0459635 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.0424273 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0410509 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0409025 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0404831 |
| IRS2 | insulin receptor substrate 2 | 0.0397728 |
| SCG2 | secretogranin II | 0.0394079 |
| STC1 | stanniocalcin 1 | 0.0382146 |
| SIK2 | salt-inducible kinase 2 | 0.0359451 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0341056 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0292771 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0290111 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0288693 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0286533 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0268418 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0265792 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0242304 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0237334 |
| TOX | thymocyte selection-associated high mobility group box | 0.0237101 |
| EGFR | epidermal growth factor receptor | 0.0229036 |
| GRAMD4 | GRAM domain containing 4 | 0.0226199 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0225973 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0223468 |
| RNF144A | ring finger protein 144A | 0.0222766 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0217679 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0208925 |
| ST18 | suppression of tumorigenicity 18, zinc finger | 0.0200798 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0197916 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0197546 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0192191 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0188427 |
| NTS | neurotensin | 0.0177972 |
| ATM | ATM serine/threonine kinase | 0.0173613 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0172974 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0172028 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0171709 |
| RPS21 | ribosomal protein S21 | 0.0170093 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0168747 |
| BRD4 | bromodomain containing 4 | 0.0167545 |
| FHIT | fragile histidine triad | 0.0164297 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0162162 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.015924 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0156823 |
| SKI | SKI proto-oncogene | 0.0155214 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0154934 |
| SVIL | supervillin | 0.0151956 |
| SP140L | SP140 nuclear body protein-like | 0.0149455 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0146782 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.014454 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.014369 |
| GOLGA3 | golgin A3 | 0.0140663 |
| WDR26 | WD repeat domain 26 | 0.0140384 |
| PALLD | palladin, cytoskeletal associated protein | 0.0138846 |
| MSN | moesin | 0.0138387 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0137051 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0135877 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0134634 |
| CAB39 | calcium binding protein 39 | 0.0134334 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0132153 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0130461 |
| PLK2 | polo-like kinase 2 | 0.0130424 |
| H1-0 | H1.0 linker histone | 0.0128416 |
| VEGFA | vascular endothelial growth factor A | 0.0126877 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0124292 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0122422 |
| ERCC5 | excision repair cross-complementation group 5 | 0.0122252 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.012187 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.0121747 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.012142 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0117785 |
| NCKAP5 | NCK-associated protein 5 | 0.0117728 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0117508 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | 0.0116584 |
| RHOQ | ras homolog family member Q | 0.0115978 |
| CEP295 | centrosomal protein 295kDa | 0.0115161 |
| ATP11A | ATPase, class VI, type 11A | 0.0114914 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0114659 |
| SRP9 | signal recognition particle 9kDa | 0.0114614 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 | 0.0112515 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0112038 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0111648 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0110834 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0109947 |
| SON | SON DNA binding protein | 0.0109223 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0107964 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.0107917 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0106808 |
| DUSP10 | dual specificity phosphatase 10 | 0.0106246 |
| ABLIM1 | actin binding LIM protein 1 | 0.0104703 |
| HOMER1 | homer scaffolding protein 1 | 0.0104666 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0103988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | -0.206306 |
| TENM1 | teneurin transmembrane protein 1 | -0.142937 |
| NRG1 | neuregulin 1 | -0.116446 |
| PTMA | prothymosin, alpha | -0.0894257 |
| ENO1 | enolase 1, (alpha) | -0.0850964 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0756237 |
| DTNA | dystrobrevin, alpha | -0.0709572 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0696434 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0681356 |
| CALCA | calcitonin-related polypeptide alpha | -0.0656139 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0641595 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0621885 |
| PEG10 | paternally expressed 10 | -0.0594666 |
| PKM | pyruvate kinase, muscle | -0.0555918 |
| RPS27A | ribosomal protein S27a | -0.0552295 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0539013 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0537812 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0533409 |
| MATR3 | matrin 3 | -0.0525874 |
| SYT1 | synaptotagmin I | -0.0517782 |
| EPHA6 | EPH receptor A6 | -0.0513196 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0509653 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0501922 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0483521 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0482998 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0475673 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0474582 |
| ESRRG | estrogen-related receptor gamma | -0.0443349 |
| GPC6 | glypican 6 | -0.0422407 |
| RORA | RAR-related orphan receptor A | -0.0416549 |
| SNTG1 | syntrophin, gamma 1 | -0.0399933 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0399648 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0393201 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0391532 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0387437 |
| GPC5 | glypican 5 | -0.0382728 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0380973 |
| CNTNAP2 | contactin associated protein-like 2 | -0.0378572 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0367981 |
| UBC | ubiquitin C | -0.0365822 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0365027 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0363785 |
| NCAM1 | neural cell adhesion molecule 1 | -0.0362597 |
| GPHN | gephyrin | -0.0354299 |
| MAP1B | microtubule-associated protein 1B | -0.0349414 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0347959 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0342766 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0341898 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0341471 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0339525 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0338953 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0335582 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0335528 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0320002 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0318901 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0309108 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0305165 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0304937 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0302818 |
| CENPF | centromere protein F, 350/400kDa | -0.0299648 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0293221 |
| STXBP5L | syntaxin binding protein 5-like | -0.0288811 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0286523 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | -0.0285703 |
| ZNF292 | zinc finger protein 292 | -0.0282834 |
| UVRAG | UV radiation resistance associated | -0.0282238 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0279707 |
| SMYD3 | SET and MYND domain containing 3 | -0.0278187 |
| TUSC3 | tumor suppressor candidate 3 | -0.0277201 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0274282 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0273725 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.027362 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0267876 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0267174 |
| ACTG1 | actin gamma 1 | -0.0264581 |
| RLF | rearranged L-myc fusion | -0.0264371 |
| CADM1 | cell adhesion molecule 1 | -0.0264211 |
| MED13L | mediator complex subunit 13-like | -0.0263511 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0260189 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0259846 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0259616 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0259315 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0258839 |
| PHIP | pleckstrin homology domain interacting protein | -0.0257258 |
| MSI2 | musashi RNA-binding protein 2 | -0.0255524 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.025379 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0252352 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.0251215 |
| RPS8 | ribosomal protein S8 | -0.0251195 |
| RPL37 | ribosomal protein L37 | -0.0250598 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.024939 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0248738 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0248506 |
| SET | SET nuclear proto-oncogene | -0.0247892 |
| PCBP2 | poly(rC) binding protein 2 | -0.024729 |
| MYT1L | myelin transcription factor 1-like | -0.0246516 |
| ZNF609 | zinc finger protein 609 | -0.0246085 |
| WWOX | WW domain containing oxidoreductase | -0.0241334 |
| RPS25 | ribosomal protein S25 | -0.0241181 |
| RPLP1 | ribosomal protein, large, P1 | -0.0241008 |
