| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.175434 |
| DST | dystonin | 0.104813 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0779743 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0697173 |
| RAD51B | RAD51 paralog B | 0.0651739 |
| NRG3 | neuregulin 3 | 0.0574302 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0571143 |
| ANGPTL4 | angiopoietin-like 4 | 0.0540818 |
| GOLGB1 | golgin B1 | 0.0528678 |
| MSN | moesin | 0.0528005 |
| ASPH | aspartate beta-hydroxylase | 0.0493016 |
| FMN1 | formin 1 | 0.0469845 |
| FHIT | fragile histidine triad | 0.0461376 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0410024 |
| RPS3 | ribosomal protein S3 | 0.0405413 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0400862 |
| HDAC9 | histone deacetylase 9 | 0.038914 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0344076 |
| SFTPA2 | surfactant protein A2 | 0.0343575 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0330885 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0328566 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0327336 |
| NLGN1 | neuroligin 1 | 0.0319191 |
| IFI44L | interferon-induced protein 44-like | 0.0314039 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.031199 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.030493 |
| TAPBP | TAP binding protein (tapasin) | 0.0304577 |
| CENPF | centromere protein F, 350/400kDa | 0.0301623 |
| TPM3 | tropomyosin 3 | 0.0291346 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0283171 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0277979 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0275892 |
| EXOC4 | exocyst complex component 4 | 0.0270768 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0259235 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0258147 |
| CFAP20DC | CFAP20 domain containing | 0.0250356 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0248164 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0245067 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0241022 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0241021 |
| PRELID2 | PRELI domain containing 2 | 0.0238724 |
| RUNX1 | runt-related transcription factor 1 | 0.0234745 |
| AMOTL1 | angiomotin like 1 | 0.0231214 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0227574 |
| FMNL2 | formin-like 2 | 0.0226168 |
| SUMF1 | sulfatase modifying factor 1 | 0.0225525 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0224141 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.022407 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0222241 |
| EHBP1 | EH domain binding protein 1 | 0.0220787 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0219778 |
| FAM219A | family with sequence similarity 219, member A | 0.0219318 |
| COMMD10 | COMM domain containing 10 | 0.0216785 |
| HDAC4 | histone deacetylase 4 | 0.0215487 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0210819 |
| CBX3 | chromobox homolog 3 | 0.0210813 |
| SON | SON DNA binding protein | 0.0209084 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0203728 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0203304 |
| FGGY | FGGY carbohydrate kinase domain containing | 0.0202601 |
| MELTF | melanotransferrin | 0.0193255 |
| IFI44 | interferon-induced protein 44 | 0.0191552 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0190545 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0189689 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0189352 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0187988 |
| ATXN1 | ataxin 1 | 0.0187227 |
| PLAT | plasminogen activator, tissue | 0.0186777 |
| OPHN1 | oligophrenin 1 | 0.018634 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0185904 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0181867 |
| RANGAP1 | Ran GTPase activating protein 1 | 0.0181273 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0180503 |
| VEGFA | vascular endothelial growth factor A | 0.0178013 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0177726 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0177097 |
| LAMB1 | laminin, beta 1 | 0.0175742 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0175127 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.017384 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0170549 |
| TOB2 | transducer of ERBB2, 2 | 0.0169216 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0169066 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0168328 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0166791 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0166536 |
| RIGI | RNA sensor RIG-I | 0.016421 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0163563 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0163062 |
| PTK2 | protein tyrosine kinase 2 | 0.0162886 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.016279 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0162759 |
| SEPTIN9 | septin 9 | 0.0162233 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.016012 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0160002 |
| RPL14 | ribosomal protein L14 | 0.01596 |
| SETBP1 | SET binding protein 1 | 0.0158037 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0157953 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0157747 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0155266 |
| UTRN | utrophin | 0.0154244 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.278907 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215264 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121239 |
| LSAMP | limbic system-associated membrane protein | -0.118765 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0971177 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0928887 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0788823 |
| PMEL | premelanosome protein | -0.0738127 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0736503 |
| FTL | ferritin, light polypeptide | -0.0720987 |
| FN1 | fibronectin 1 | -0.0713331 |
| UBC | ubiquitin C | -0.0704273 |
| SQSTM1 | sequestosome 1 | -0.0702051 |
| RPLP1 | ribosomal protein, large, P1 | -0.0672639 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0638322 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0628119 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0564717 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0555594 |
| CCND1 | cyclin D1 | -0.0531028 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0519111 |
| IER3 | immediate early response 3 | -0.0497915 |
| PGK1 | phosphoglycerate kinase 1 | -0.0493382 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0490824 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0489297 |
| ENO1 | enolase 1, (alpha) | -0.047902 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0467088 |
| ACTG1 | actin gamma 1 | -0.0455927 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0454991 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0453871 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0452211 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0449738 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0431243 |
| SPAG9 | sperm associated antigen 9 | -0.0409564 |
| RPS24 | ribosomal protein S24 | -0.038196 |
| CANX | calnexin | -0.0379238 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0371349 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0367913 |
| WDR45B | WD repeat domain 45B | -0.0363945 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0357804 |
| TMSB10 | thymosin beta 10 | -0.0351468 |
| PKM | pyruvate kinase, muscle | -0.0338976 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0331068 |
| CA8 | carbonic anhydrase VIII | -0.0329394 |
| TKT | transketolase | -0.0315997 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0314913 |
| RPS27A | ribosomal protein S27a | -0.0312583 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0311815 |
| RHOA | ras homolog family member A | -0.0297568 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0296831 |
| MT2A | metallothionein 2A | -0.0294123 |
| EXT1 | exostosin glycosyltransferase 1 | -0.029401 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0293787 |
| CTSD | cathepsin D | -0.0293455 |
| TFG | TRK-fused gene | -0.0287155 |
| HLA-E | major histocompatibility complex, class I, E | -0.0286981 |
| RLF | rearranged L-myc fusion | -0.0273345 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0272839 |
| RPS16 | ribosomal protein S16 | -0.0271771 |
| CALU | calumenin | -0.0260421 |
| RPS8 | ribosomal protein S8 | -0.0260116 |
| RPL31 | ribosomal protein L31 | -0.0256995 |
| HMGA1 | high mobility group AT-hook 1 | -0.0255175 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0252841 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0252453 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0251963 |
| PTMA | prothymosin, alpha | -0.0251608 |
| MSI2 | musashi RNA-binding protein 2 | -0.0248457 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0248446 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0248292 |
| TFRC | transferrin receptor | -0.024649 |
| ZNF292 | zinc finger protein 292 | -0.0242965 |
| RPS5 | ribosomal protein S5 | -0.0241256 |
| USP3 | ubiquitin specific peptidase 3 | -0.0240633 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0236284 |
| SRP54 | signal recognition particle 54kDa | -0.0232317 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0230733 |
| RPS20 | ribosomal protein S20 | -0.0230475 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0229229 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0227983 |
| CLINT1 | clathrin interactor 1 | -0.022767 |
| RHEB | Ras homolog enriched in brain | -0.0227178 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0226087 |
| ANXA2 | annexin A2 | -0.0226081 |
| ARF1 | ADP-ribosylation factor 1 | -0.0225193 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0224091 |
| GNAS | GNAS complex locus | -0.0223896 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.022261 |
| CALR | calreticulin | -0.0219811 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0219431 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.0217406 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0216471 |
| RPL38 | ribosomal protein L38 | -0.021387 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0210015 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0208879 |
| RPL39 | ribosomal protein L39 | -0.020859 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0208234 |
| RPL28 | ribosomal protein L28 | -0.0206304 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0206208 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0206165 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0205386 |
