| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.141837 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0857172 |
| TMSB10 | thymosin beta 10 | 0.0805152 |
| GLIS3 | GLIS family zinc finger 3 | 0.0799546 |
| INHBA | inhibin, beta A | 0.0697706 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0558135 |
| RPS3 | ribosomal protein S3 | 0.0555529 |
| RPL35A | ribosomal protein L35a | 0.0445508 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0442889 |
| KYNU | kynureninase | 0.0438587 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0437957 |
| RPS21 | ribosomal protein S21 | 0.04298 |
| MT2A | metallothionein 2A | 0.0412047 |
| AHNAK | AHNAK nucleoprotein | 0.0385659 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0378248 |
| PTMA | prothymosin, alpha | 0.0375066 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0366702 |
| COL5A1 | collagen, type V, alpha 1 | 0.0359521 |
| RPL14 | ribosomal protein L14 | 0.0356722 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0337384 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0330348 |
| INTS6 | integrator complex subunit 6 | 0.0320683 |
| VCL | vinculin | 0.0316204 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0306503 |
| NTN4 | netrin 4 | 0.0306231 |
| RPL23 | ribosomal protein L23 | 0.0300312 |
| RPL26 | ribosomal protein L26 | 0.0289152 |
| IER3 | immediate early response 3 | 0.0286782 |
| CAVIN1 | caveolae associated protein 1 | 0.0286199 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0285747 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0278886 |
| TOP1 | topoisomerase (DNA) I | 0.0273575 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0272191 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0271123 |
| TUT7 | terminal uridylyl transferase 7 | 0.0258939 |
| RPL34 | ribosomal protein L34 | 0.0250464 |
| HMGA2 | high mobility group AT-hook 2 | 0.0248291 |
| RPL36 | ribosomal protein L36 | 0.0245244 |
| HLA-B | major histocompatibility complex, class I, B | 0.0245161 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0242686 |
| RPS4X | ribosomal protein S4, X-linked | 0.0242631 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0241765 |
| RPS12 | ribosomal protein S12 | 0.0238848 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0237856 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0236048 |
| ANKRD11 | ankyrin repeat domain 11 | 0.023559 |
| MT1X | metallothionein 1X | 0.0235252 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0232708 |
| RPL12 | ribosomal protein L12 | 0.0232632 |
| TMEM263 | transmembrane protein 263 | 0.0230784 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.023074 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0230458 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.023039 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0224765 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0223409 |
| DUSP10 | dual specificity phosphatase 10 | 0.0223141 |
| FTL | ferritin, light polypeptide | 0.0222072 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0221734 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0219929 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0218962 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0212418 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0210642 |
| RPLP2 | ribosomal protein, large, P2 | 0.0208952 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0207998 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0207552 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0203437 |
| KLF6 | Kruppel-like factor 6 | 0.0202379 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0199323 |
| RPS6 | ribosomal protein S6 | 0.019313 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0190546 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0184248 |
| RPL37A | ribosomal protein L37a | 0.0184055 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0183031 |
| RPS19 | ribosomal protein S19 | 0.0182699 |
| JAG1 | jagged 1 | 0.0181681 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0181587 |
| CDH13 | cadherin 13 | 0.0181179 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0180959 |
| RPL9 | ribosomal protein L9 | 0.0180494 |
| BRD4 | bromodomain containing 4 | 0.0175514 |
| CUL3 | cullin 3 | 0.0174531 |
| MIDN | midnolin | 0.0174031 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0167172 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0165301 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0164944 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0163586 |
| TLE4 | transducin-like enhancer of split 4 | 0.0163348 |
| BICC1 | BicC family RNA binding protein 1 | 0.0163198 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0161 |
| FAM20C | family with sequence similarity 20, member C | 0.016089 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0159647 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.0159554 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0157161 |
| NRN1 | neuritin 1 | 0.0155757 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0153211 |
| NABP1 | nucleic acid binding protein 1 | 0.0152824 |
| PMM2 | phosphomannomutase 2 | 0.0152821 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0152706 |
| CD63 | CD63 molecule | 0.0152533 |
| RRBP1 | ribosome binding protein 1 | 0.0151075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.244924 |
| FN1 | fibronectin 1 | -0.177535 |
| FRMD4A | FERM domain containing 4A | -0.116974 |
| FNDC3B | fibronectin type III domain containing 3B | -0.111309 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.108663 |
| NDRG1 | N-myc downstream regulated 1 | -0.101916 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.100943 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0969069 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0923894 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0891631 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0870429 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.085962 |
| VIM | vimentin | -0.0752663 |
| PDE10A | phosphodiesterase 10A | -0.074087 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0725805 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0720195 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0714362 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0712743 |
| CADM1 | cell adhesion molecule 1 | -0.0707963 |
| ZNF292 | zinc finger protein 292 | -0.0682043 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0676245 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0662234 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0657362 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.064111 |
| PKM | pyruvate kinase, muscle | -0.0622689 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0605856 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0604547 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0602249 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0559427 |
| SBF2 | SET binding factor 2 | -0.0548898 |
| SPAG9 | sperm associated antigen 9 | -0.0547298 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0542268 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0533241 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0533124 |
| VCAN | versican | -0.0531598 |
| ARRDC3 | arrestin domain containing 3 | -0.0523473 |
| HLA-E | major histocompatibility complex, class I, E | -0.0523337 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0521309 |
| LDHA | lactate dehydrogenase A | -0.0510412 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0505339 |
| CDCP1 | CUB domain containing protein 1 | -0.0504394 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0503964 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0497673 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0495976 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0473764 |
| MMP12 | matrix metallopeptidase 12 | -0.0472967 |
| ENO1 | enolase 1, (alpha) | -0.0471316 |
| PLIN2 | perilipin 2 | -0.0470442 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0458667 |
| SMAD3 | SMAD family member 3 | -0.0451307 |
| PGK1 | phosphoglycerate kinase 1 | -0.0448046 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0432847 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.042232 |
| VEGFA | vascular endothelial growth factor A | -0.0418432 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0418112 |
| EGR1 | early growth response 1 | -0.0407804 |
| PCBP2 | poly(rC) binding protein 2 | -0.0403187 |
| ARFGEF3 | ARFGEF family member 3 | -0.040046 |
| UBC | ubiquitin C | -0.0394746 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0392367 |
| MX1 | MX dynamin-like GTPase 1 | -0.0389306 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0388798 |
| NAV2 | neuron navigator 2 | -0.0377423 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0374503 |
| NGLY1 | N-glycanase 1 | -0.0371052 |
| RTN4 | reticulon 4 | -0.0370838 |
| ARF4 | ADP-ribosylation factor 4 | -0.0369815 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0365461 |
| SNX9 | sorting nexin 9 | -0.0364284 |
| TNS3 | tensin 3 | -0.0361587 |
| RAI14 | retinoic acid induced 14 | -0.0353619 |
| TPM4 | tropomyosin 4 | -0.0353288 |
| WDR45B | WD repeat domain 45B | -0.0350165 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0338558 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0331831 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0330258 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0329366 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0324016 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0322299 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0321596 |
| RPS2 | ribosomal protein S2 | -0.0319766 |
| CENPF | centromere protein F, 350/400kDa | -0.0317853 |
| PHF21A | PHD finger protein 21A | -0.0313448 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0311848 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0309161 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0308447 |
| COL1A2 | collagen, type I, alpha 2 | -0.0308328 |
| CTSD | cathepsin D | -0.0302134 |
| IL6ST | interleukin 6 signal transducer | -0.0301102 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0299204 |
| C3 | complement component 3 | -0.0298707 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0296251 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0295022 |
| FAM13A | family with sequence similarity 13, member A | -0.0294684 |
| DSTN | destrin (actin depolymerizing factor) | -0.0293725 |
| RPL39 | ribosomal protein L39 | -0.0290549 |
| MATR3 | matrin 3 | -0.029022 |
| OPTN | optineurin | -0.0289829 |
| SNX3 | sorting nexin 3 | -0.0289025 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0285428 |
