| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.126539 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.110088 |
| B2M | beta-2-microglobulin | 0.0937745 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0764607 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0760451 |
| CD44 | CD44 molecule (Indian blood group) | 0.0720587 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0645843 |
| FNDC3B | fibronectin type III domain containing 3B | 0.060794 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0606806 |
| MSN | moesin | 0.0603316 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0586723 |
| RND3 | Rho family GTPase 3 | 0.058568 |
| ARRDC3 | arrestin domain containing 3 | 0.0570209 |
| PTMA | prothymosin, alpha | 0.0543135 |
| RPS6 | ribosomal protein S6 | 0.0542196 |
| KYNU | kynureninase | 0.052228 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0521102 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0517326 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0508133 |
| TPM3 | tropomyosin 3 | 0.0504499 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0486919 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0485212 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0475374 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0471262 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.045632 |
| MAP1B | microtubule-associated protein 1B | 0.0455122 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0452373 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0438753 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0431314 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0430414 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0419867 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0415362 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0411504 |
| RBM39 | RNA binding motif protein 39 | 0.0407672 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0402693 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0395747 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0388921 |
| TAPBP | TAP binding protein (tapasin) | 0.0382057 |
| CALD1 | caldesmon 1 | 0.0376394 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0372879 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0358291 |
| RTN4 | reticulon 4 | 0.0352156 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0349543 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0344154 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0334201 |
| CD63 | CD63 molecule | 0.0333899 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0333577 |
| TXNIP | thioredoxin interacting protein | 0.0332985 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0332788 |
| BRD4 | bromodomain containing 4 | 0.0327643 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0327315 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0326763 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0323822 |
| KLC1 | kinesin light chain 1 | 0.0323549 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0323507 |
| S100A9 | S100 calcium binding protein A9 | 0.0323317 |
| RPS2 | ribosomal protein S2 | 0.0322425 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.03201 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0318686 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0318655 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0316027 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0313814 |
| FMNL2 | formin-like 2 | 0.0313167 |
| TLN1 | talin 1 | 0.0310604 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0308872 |
| FOSL1 | FOS-like antigen 1 | 0.0307703 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0305607 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0303943 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0301715 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0301321 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0298543 |
| HDAC9 | histone deacetylase 9 | 0.0297148 |
| CTSB | cathepsin B | 0.0293595 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0287492 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0287034 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0285411 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0284926 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0284091 |
| YTHDC1 | YTH domain containing 1 | 0.0283629 |
| RPL7 | ribosomal protein L7 | 0.0282918 |
| ERBIN | erbb2 interacting protein | 0.0282495 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0282337 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0279065 |
| RPS12 | ribosomal protein S12 | 0.0278905 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0278285 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0273568 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0273538 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0272282 |
| RPS3 | ribosomal protein S3 | 0.0271801 |
| RBM25 | RNA binding motif protein 25 | 0.0271618 |
| MATR3 | matrin 3 | 0.0268835 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0267521 |
| CCNL1 | cyclin L1 | 0.026727 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0265664 |
| MYOF | myoferlin | 0.0265538 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0265497 |
| PMM2 | phosphomannomutase 2 | 0.025994 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0258285 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0257885 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.025442 |
| Symbol | Name | Standardized Value |
|---|---|---|
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.135465 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.109582 |
| FN1 | fibronectin 1 | -0.106696 |
| LOX | lysyl oxidase | -0.101648 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0954775 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0923638 |
| HLA-B | major histocompatibility complex, class I, B | -0.0911941 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0880206 |
| CDH13 | cadherin 13 | -0.0866232 |
| KAZN | kazrin, periplakin interacting protein | -0.0861051 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0834752 |
| CALU | calumenin | -0.0798593 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0706283 |
| HMGA2 | high mobility group AT-hook 2 | -0.067806 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0665512 |
| NRXN3 | neurexin 3 | -0.0648527 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0597224 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0593513 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0585534 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0543771 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0542949 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0522785 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0519527 |
| TNS3 | tensin 3 | -0.0516928 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0497588 |
| COG6 | component of oligomeric golgi complex 6 | -0.0477741 |
| HLA-A | major histocompatibility complex, class I, A | -0.0476667 |
| HLA-C | major histocompatibility complex, class I, C | -0.0465163 |
| COL1A2 | collagen, type I, alpha 2 | -0.0452554 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.044107 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0436953 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0417549 |
| AHNAK | AHNAK nucleoprotein | -0.04121 |
| RAI14 | retinoic acid induced 14 | -0.0400779 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0394488 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.039393 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0389284 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0387419 |
| PGK1 | phosphoglycerate kinase 1 | -0.0385352 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0377877 |
| TPM4 | tropomyosin 4 | -0.0364643 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0363704 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0360762 |
| FBXO11 | F-box protein 11 | -0.0354878 |
| GNAS | GNAS complex locus | -0.0354535 |
| ATXN1 | ataxin 1 | -0.0353795 |
| PRSS23 | protease, serine, 23 | -0.0348636 |
| CA12 | carbonic anhydrase XII | -0.0345076 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0342586 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0338667 |
| EFNA5 | ephrin-A5 | -0.0335816 |
| CADM1 | cell adhesion molecule 1 | -0.0334418 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0331722 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0331263 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0326517 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0325915 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0325788 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0321101 |
| CANX | calnexin | -0.0318562 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.03162 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0313127 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0310237 |
| RAD51B | RAD51 paralog B | -0.0308281 |
| COL5A1 | collagen, type V, alpha 1 | -0.0308207 |
| IL6 | interleukin 6 | -0.0305093 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0303422 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0302241 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0299838 |
| CLIC4 | chloride intracellular channel 4 | -0.0295723 |
| TPM1 | tropomyosin 1 (alpha) | -0.0292219 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0291399 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0288722 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0284659 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0281334 |
| GOLM2 | golgi membrane protein 2 | -0.0281151 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0280042 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.027602 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0275961 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.027509 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0273159 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0271233 |
| HM13 | histocompatibility (minor) 13 | -0.0270631 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.026927 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0266242 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0263683 |
| VCL | vinculin | -0.0262745 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0258992 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0258603 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0257545 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0255682 |
| OSMR | oncostatin M receptor | -0.0249413 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0246609 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0245687 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0245278 |
| LYST | lysosomal trafficking regulator | -0.0245106 |
| COL5A2 | collagen, type V, alpha 2 | -0.0244758 |
| GOLGA4 | golgin A4 | -0.0242801 |
| IKBIP | IKBKB interacting protein | -0.024179 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0241715 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0234968 |
