| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.0762068 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0578976 |
| ASPH | aspartate beta-hydroxylase | 0.0522689 |
| ANGPTL4 | angiopoietin-like 4 | 0.0515485 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0502502 |
| GPC5 | glypican 5 | 0.0463781 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.04542 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0448835 |
| MAP1B | microtubule-associated protein 1B | 0.0435719 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0423712 |
| LDHA | lactate dehydrogenase A | 0.0411274 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.040602 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0356878 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0352434 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0351011 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0349831 |
| SERINC1 | serine incorporator 1 | 0.0320037 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.031497 |
| TAPBP | TAP binding protein (tapasin) | 0.0312753 |
| ATM | ATM serine/threonine kinase | 0.0311062 |
| MMP10 | matrix metallopeptidase 10 | 0.0307154 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0301123 |
| RPL26 | ribosomal protein L26 | 0.0300557 |
| TMF1 | TATA element modulatory factor 1 | 0.0300083 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0297841 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0294011 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0292167 |
| GOLGB1 | golgin B1 | 0.0288508 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0287092 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0285276 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.028157 |
| INTS6 | integrator complex subunit 6 | 0.0278061 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0275125 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274581 |
| PRR16 | proline rich 16 | 0.0274548 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0262286 |
| HLA-B | major histocompatibility complex, class I, B | 0.0260914 |
| PYGL | phosphorylase, glycogen, liver | 0.0256635 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0249443 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0248533 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0247728 |
| ENO1 | enolase 1, (alpha) | 0.0246564 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0245291 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0244143 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0243011 |
| LMNA | lamin A/C | 0.0241312 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0239683 |
| JAK1 | Janus kinase 1 | 0.023886 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0235559 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0235252 |
| EHBP1 | EH domain binding protein 1 | 0.0234058 |
| SATB2 | SATB homeobox 2 | 0.0233407 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0232848 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0231197 |
| DST | dystonin | 0.0230086 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0230085 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0229836 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0229755 |
| BMP6 | bone morphogenetic protein 6 | 0.0229086 |
| RC3H2 | ring finger and CCCH-type domains 2 | 0.0228346 |
| ACTG1 | actin gamma 1 | 0.0228234 |
| NEK7 | NIMA-related kinase 7 | 0.0227569 |
| CD2AP | CD2-associated protein | 0.0224076 |
| RNF217 | ring finger protein 217 | 0.0222851 |
| ATXN1 | ataxin 1 | 0.0222471 |
| FYTTD1 | forty-two-three domain containing 1 | 0.0221669 |
| MYO9A | myosin IXA | 0.0221288 |
| KIAA0319L | KIAA0319-like | 0.0220736 |
| RPS21 | ribosomal protein S21 | 0.0219798 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0219393 |
| PSEN1 | presenilin 1 | 0.0218483 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0217846 |
| EP400 | E1A binding protein p400 | 0.0217459 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0217117 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0215753 |
| TMEM245 | transmembrane protein 245 | 0.0215591 |
| NBEA | neurobeachin | 0.0215521 |
| RPS27A | ribosomal protein S27a | 0.0214147 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0211858 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0211553 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.021133 |
| NCK1 | NCK adaptor protein 1 | 0.0210366 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0206305 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0205962 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0205955 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0205478 |
| JUN | jun proto-oncogene | 0.0203544 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0201543 |
| FCHO2 | FCH domain only 2 | 0.0200147 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0199247 |
| UBC | ubiquitin C | 0.0198806 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0197493 |
| TXNIP | thioredoxin interacting protein | 0.0197438 |
| ZNF75D | zinc finger protein 75D | 0.0197369 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0197091 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0196998 |
| CAVIN1 | caveolae associated protein 1 | 0.019614 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0195958 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0195847 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0194848 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.165152 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124214 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0599219 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0581681 |
| RBM39 | RNA binding motif protein 39 | -0.05725 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.055267 |
| FMNL2 | formin-like 2 | -0.05366 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0479618 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0477673 |
| CD44 | CD44 molecule (Indian blood group) | -0.0477252 |
| IL6ST | interleukin 6 signal transducer | -0.0457867 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0448369 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0444542 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0441824 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.042587 |
| RAD51B | RAD51 paralog B | -0.0424583 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0424062 |
| ZNF292 | zinc finger protein 292 | -0.0424028 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0417529 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0411843 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0411087 |
| HELZ | helicase with zinc finger | -0.0410457 |
| DTNA | dystrobrevin, alpha | -0.0408476 |
| SPAG9 | sperm associated antigen 9 | -0.040364 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0399223 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0398982 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0398495 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0393784 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0392119 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0391703 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.0383951 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0383907 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0381915 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.038119 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0372408 |
| YBX3 | Y box binding protein 3 | -0.0371399 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0368041 |
| ERBIN | erbb2 interacting protein | -0.0362947 |
| EGR1 | early growth response 1 | -0.036231 |
| LAMA5 | laminin, alpha 5 | -0.035711 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0353543 |
| SMYD3 | SET and MYND domain containing 3 | -0.0351197 |
| PCNX4 | pecanex 4 | -0.0349597 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.0344878 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.034151 |
| YAP1 | Yes-associated protein 1 | -0.0335949 |
| PHF21A | PHD finger protein 21A | -0.0333592 |
| RIGI | RNA sensor RIG-I | -0.0333498 |
| USP15 | ubiquitin specific peptidase 15 | -0.0330853 |
| NAV2 | neuron navigator 2 | -0.0328694 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0321025 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0320909 |
| NF1 | neurofibromin 1 | -0.0314671 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0312083 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0311468 |
| SNX13 | sorting nexin 13 | -0.0310203 |
| NUP58 | nucleoporin 58 | -0.0310069 |
| CLIC4 | chloride intracellular channel 4 | -0.0307031 |
| GPHN | gephyrin | -0.0305289 |
| USP34 | ubiquitin specific peptidase 34 | -0.03051 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0304504 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0302785 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0295704 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0293349 |
| OXSR1 | oxidative stress responsive 1 | -0.0292423 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0291431 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0289997 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0289865 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0289775 |
| NPAT | nuclear protein, ataxia-telangiectasia locus | -0.0287061 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0286865 |
| XPO1 | exportin 1 | -0.0284235 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0280084 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0279715 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0279605 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0278832 |
| PER1 | period circadian clock 1 | -0.0278038 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0277151 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0275726 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0274845 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0274473 |
| TPX2 | TPX2, microtubule-associated | -0.0273251 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0272941 |
| MED17 | mediator complex subunit 17 | -0.0272639 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0271348 |
| RDX | radixin | -0.0271027 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0270016 |
| SMAD3 | SMAD family member 3 | -0.0268371 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0267876 |
| STAG2 | stromal antigen 2 | -0.0267505 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0266621 |
| UBP1 | upstream binding protein 1 (LBP-1a) | -0.0266186 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0265766 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0264276 |
| SETD5 | SET domain containing 5 | -0.0263789 |
| CEP250 | centrosomal protein 250kDa | -0.0263525 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -0.0263098 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.026051 |
| CCDC91 | coiled-coil domain containing 91 | -0.0258887 |
| PCNX1 | pecanex 1 | -0.0258385 |
