| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.13097 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.121359 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.108575 |
| TMEM156 | transmembrane protein 156 | 0.101308 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0972425 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0837959 |
| SFTPA2 | surfactant protein A2 | 0.0832198 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0810037 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0798748 |
| TPR | translocated promoter region, nuclear basket protein | 0.0793515 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0747093 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0697617 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0690278 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0686872 |
| NTN4 | netrin 4 | 0.0671607 |
| B2M | beta-2-microglobulin | 0.065789 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0643561 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0640592 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0614456 |
| ASPH | aspartate beta-hydroxylase | 0.0597086 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0596813 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0589194 |
| TOP1 | topoisomerase (DNA) I | 0.0589082 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.057015 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0569531 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0551745 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0550529 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0529505 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0528815 |
| GOLGA4 | golgin A4 | 0.0524335 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0514448 |
| RND3 | Rho family GTPase 3 | 0.0497424 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0483082 |
| TPM3 | tropomyosin 3 | 0.0476477 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.046829 |
| RTN4 | reticulon 4 | 0.0456704 |
| YBX3 | Y box binding protein 3 | 0.0438905 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0437925 |
| TMF1 | TATA element modulatory factor 1 | 0.0430683 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.042914 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0426822 |
| DUSP6 | dual specificity phosphatase 6 | 0.0423522 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0421049 |
| GPATCH2L | G patch domain containing 2-like | 0.0409567 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0402163 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0399914 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.039063 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0388025 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0377794 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.037653 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0376099 |
| RAI14 | retinoic acid induced 14 | 0.037451 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0374216 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0368157 |
| CENPF | centromere protein F, 350/400kDa | 0.0367452 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0366835 |
| FAT1 | FAT atypical cadherin 1 | 0.0366633 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0362256 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0361486 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0350014 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0348355 |
| DSTN | destrin (actin depolymerizing factor) | 0.0345284 |
| SVIL | supervillin | 0.0339911 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0337465 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0334072 |
| ITGA1 | integrin, alpha 1 | 0.0330593 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0329272 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0328796 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0328266 |
| SERINC1 | serine incorporator 1 | 0.0326389 |
| STC2 | stanniocalcin 2 | 0.0323942 |
| ENO1 | enolase 1, (alpha) | 0.0319817 |
| TXNRD1 | thioredoxin reductase 1 | 0.0319415 |
| VMP1 | vacuole membrane protein 1 | 0.0317674 |
| SON | SON DNA binding protein | 0.0314755 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0312255 |
| CTSB | cathepsin B | 0.0307558 |
| CALR | calreticulin | 0.0306645 |
| UBXN4 | UBX domain protein 4 | 0.0306538 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0303366 |
| PALLD | palladin, cytoskeletal associated protein | 0.030215 |
| CUL3 | cullin 3 | 0.0300461 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0300235 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0298977 |
| KIF5B | kinesin family member 5B | 0.0294134 |
| RASAL2 | RAS protein activator like 2 | 0.0293426 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0293133 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0292858 |
| NOTCH2 | notch 2 | 0.0288313 |
| WBP11 | WW domain binding protein 11 | 0.0288309 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0286393 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.028626 |
| LMNA | lamin A/C | 0.0283271 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0281975 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0276574 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0274726 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0271966 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0271671 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0269765 |
| BRD2 | bromodomain containing 2 | 0.0268512 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.341775 |
| FN1 | fibronectin 1 | -0.164201 |
| NRG1 | neuregulin 1 | -0.145861 |
| TMSB10 | thymosin beta 10 | -0.0733232 |
| PKM | pyruvate kinase, muscle | -0.0656193 |
| HMGA2 | high mobility group AT-hook 2 | -0.065077 |
| RPLP1 | ribosomal protein, large, P1 | -0.0643367 |
| NDRG1 | N-myc downstream regulated 1 | -0.0642013 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0623817 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0622865 |
| INTS6 | integrator complex subunit 6 | -0.0567891 |
| RPS24 | ribosomal protein S24 | -0.0446311 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0445309 |
| CADM1 | cell adhesion molecule 1 | -0.0438831 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0434219 |
| AEBP2 | AE binding protein 2 | -0.0426919 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0423518 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.039549 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0394049 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0384216 |
| FAM20C | family with sequence similarity 20, member C | -0.0372907 |
| RPS25 | ribosomal protein S25 | -0.0370032 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0360567 |
| LRRC23 | leucine rich repeat containing 23 | -0.0357479 |
| IER3 | immediate early response 3 | -0.0352879 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0346091 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0331619 |
| RPS11 | ribosomal protein S11 | -0.0317772 |
| HLA-B | major histocompatibility complex, class I, B | -0.0314485 |
| RPS23 | ribosomal protein S23 | -0.0312692 |
| RPS16 | ribosomal protein S16 | -0.0306325 |
| RAD51B | RAD51 paralog B | -0.0305006 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0303217 |
| RPS20 | ribosomal protein S20 | -0.0302131 |
| GNAS | GNAS complex locus | -0.0300485 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0294303 |
| RPS19 | ribosomal protein S19 | -0.02835 |
| RPS29 | ribosomal protein S29 | -0.0282981 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0281903 |
| RPL31 | ribosomal protein L31 | -0.0273653 |
| GLIS3 | GLIS family zinc finger 3 | -0.0271668 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266968 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0259415 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0255543 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.02527 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0251945 |
| S100A6 | S100 calcium binding protein A6 | -0.0250842 |
| RPL28 | ribosomal protein L28 | -0.0249359 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0247627 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0243695 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0243217 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0237734 |
| PRELID2 | PRELI domain containing 2 | -0.0235672 |
| RPL23 | ribosomal protein L23 | -0.0233433 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0233307 |
| CTSD | cathepsin D | -0.0231222 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.0229528 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0228543 |
| SUMF1 | sulfatase modifying factor 1 | -0.0227417 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0223842 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0223075 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0219224 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0218676 |
| TENM4 | teneurin transmembrane protein 4 | -0.0217438 |
| RPL19 | ribosomal protein L19 | -0.0215139 |
| ARF1 | ADP-ribosylation factor 1 | -0.0214595 |
| RPL38 | ribosomal protein L38 | -0.0214422 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0213848 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0213078 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.021149 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0211321 |
| RPLP2 | ribosomal protein, large, P2 | -0.0207836 |
| AOPEP | aminopeptidase O (putative) | -0.0205136 |
| ZNF292 | zinc finger protein 292 | -0.0202531 |
| CD109 | CD109 molecule | -0.0198569 |
| ACTN4 | actinin, alpha 4 | -0.0198562 |
| EXOC4 | exocyst complex component 4 | -0.0196733 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0194574 |
| FHIT | fragile histidine triad | -0.0192164 |
| HMGA1 | high mobility group AT-hook 1 | -0.0190849 |
| S100A10 | S100 calcium binding protein A10 | -0.0185328 |
| ATG7 | autophagy related 7 | -0.0184546 |
| RPS15 | ribosomal protein S15 | -0.0183401 |
| RPLP0 | ribosomal protein, large, P0 | -0.018315 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0182937 |
| COG5 | component of oligomeric golgi complex 5 | -0.0182926 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0180809 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0180555 |
| AUTS2 | autism susceptibility candidate 2 | -0.0178202 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0177762 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0177466 |
| CCND1 | cyclin D1 | -0.0176705 |
| TBCA | tubulin folding cofactor A | -0.0173252 |
| PRKCA | protein kinase C, alpha | -0.0171342 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0170592 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0169799 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0169611 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0169 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0168412 |
| DENND4C | DENN/MADD domain containing 4C | -0.0167916 |