| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.129329 |
| RPS6 | ribosomal protein S6 | 0.0934344 |
| RPS3 | ribosomal protein S3 | 0.0908 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0877881 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0854361 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0853211 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0851823 |
| FTL | ferritin, light polypeptide | 0.0817249 |
| GOLGA4 | golgin A4 | 0.0795589 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0787001 |
| GOLGB1 | golgin B1 | 0.0773061 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0717308 |
| TMF1 | TATA element modulatory factor 1 | 0.0620169 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0611957 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0608911 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0608869 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0587771 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0554647 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.054678 |
| PGK1 | phosphoglycerate kinase 1 | 0.052991 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0522729 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0512245 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0498271 |
| AHNAK | AHNAK nucleoprotein | 0.0480753 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.047635 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0468474 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0462209 |
| B2M | beta-2-microglobulin | 0.0460745 |
| TOP1 | topoisomerase (DNA) I | 0.0460488 |
| NEBL | nebulette | 0.0454885 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0454557 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.045218 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0435792 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0435603 |
| RPL35A | ribosomal protein L35a | 0.0435488 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0435138 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0428505 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0423087 |
| HKDC1 | hexokinase domain containing 1 | 0.0411588 |
| RPS21 | ribosomal protein S21 | 0.0410345 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0405076 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0402297 |
| RND3 | Rho family GTPase 3 | 0.0402181 |
| HDLBP | high density lipoprotein binding protein | 0.0401004 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0399138 |
| RPL13A | ribosomal protein L13a | 0.0392689 |
| RPS12 | ribosomal protein S12 | 0.0388581 |
| RPL14 | ribosomal protein L14 | 0.0388311 |
| KIF5B | kinesin family member 5B | 0.0381025 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0380277 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0379846 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0379778 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0379156 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0376132 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0371921 |
| H1-0 | H1.0 linker histone | 0.0364755 |
| SFTPA2 | surfactant protein A2 | 0.0363047 |
| BRD2 | bromodomain containing 2 | 0.0361179 |
| CUL3 | cullin 3 | 0.036113 |
| RPS8 | ribosomal protein S8 | 0.0358896 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0358681 |
| LAMB3 | laminin, beta 3 | 0.0349621 |
| RPL37A | ribosomal protein L37a | 0.0348627 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0346637 |
| SMYD3 | SET and MYND domain containing 3 | 0.0346599 |
| FAM107B | family with sequence similarity 107, member B | 0.0343363 |
| ZFAND5 | zinc finger, AN1-type domain 5 | 0.0342286 |
| PRELID2 | PRELI domain containing 2 | 0.0341031 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0333558 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0333339 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0330636 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0329451 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.032925 |
| RBM39 | RNA binding motif protein 39 | 0.0328855 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0327904 |
| ASPH | aspartate beta-hydroxylase | 0.0326565 |
| CANX | calnexin | 0.0326095 |
| JUN | jun proto-oncogene | 0.0326062 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0321453 |
| DSPP | dentin sialophosphoprotein | 0.0321161 |
| RPS27A | ribosomal protein S27a | 0.0320779 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.031947 |
| TPR | translocated promoter region, nuclear basket protein | 0.0319097 |
| ATXN1 | ataxin 1 | 0.0314373 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0312688 |
| TJP1 | tight junction protein 1 | 0.0309891 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.030965 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0309409 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0308096 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0307461 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0306713 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0306312 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0306168 |
| CENPF | centromere protein F, 350/400kDa | 0.0306046 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0305885 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0305777 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0304696 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.030033 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0298934 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0298624 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAML2 | mastermind-like 2 (Drosophila) | -0.0740113 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0703864 |
| TMEM123 | transmembrane protein 123 | -0.0627792 |
| CCND1 | cyclin D1 | -0.0565213 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0500531 |
| PERP | PERP, TP53 apoptosis effector | -0.0431276 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0419467 |
| KRT8 | keratin 8, type II | -0.0390071 |
| HMGA1 | high mobility group AT-hook 1 | -0.0381466 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.037952 |
| CTSD | cathepsin D | -0.0357545 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0321772 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0297366 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0284589 |
| PKM | pyruvate kinase, muscle | -0.0283074 |
| ZNF207 | zinc finger protein 207 | -0.0279785 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0273954 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0269335 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0267207 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0266771 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0262347 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0259468 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0252911 |
| TOB1 | transducer of ERBB2, 1 | -0.0238614 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0237425 |
| RYBP | RING1 and YY1 binding protein | -0.0234424 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0226275 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0224159 |
| S100A6 | S100 calcium binding protein A6 | -0.021596 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0214845 |
| JUP | junction plakoglobin | -0.0213529 |
| CST3 | cystatin C | -0.0210686 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0209393 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0208793 |
| DIAPH2 | diaphanous-related formin 2 | -0.020793 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.020734 |
| S100A10 | S100 calcium binding protein A10 | -0.0206788 |
| CAPN1 | calpain 1, (mu/I) large subunit | -0.0206268 |
| KRT18 | keratin 18, type I | -0.0205973 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0205739 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0202557 |
| MED13L | mediator complex subunit 13-like | -0.0200795 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | -0.0198989 |
| RPS25 | ribosomal protein S25 | -0.0197585 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0194569 |
| EGR1 | early growth response 1 | -0.0193261 |
| IER3 | immediate early response 3 | -0.0192212 |
| ITGB4 | integrin, beta 4 | -0.0190875 |
| VCL | vinculin | -0.0190568 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0190051 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0188416 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0186678 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0184121 |
| SPNS2 | spinster homolog 2 (Drosophila) | -0.0184088 |
| TWF1 | twinfilin actin binding protein 1 | -0.0181121 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0179362 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0179306 |
| TMEM47 | transmembrane protein 47 | -0.0178873 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0176112 |
| RHEB | Ras homolog enriched in brain | -0.0174486 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0174395 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0172726 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.0168085 |
| CDCP1 | CUB domain containing protein 1 | -0.016607 |
| H2AC6 | H2A clustered histone 6 | -0.016592 |
| H3-3B | H3.3 histone B | -0.0163125 |
| ITGB8 | integrin, beta 8 | -0.0162617 |
| PARD6B | par-6 family cell polarity regulator beta | -0.016096 |
| BMP6 | bone morphogenetic protein 6 | -0.0160706 |
| SF1 | splicing factor 1 | -0.0160196 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0159204 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0158356 |
| S100A2 | S100 calcium binding protein A2 | -0.0157009 |
| POTEF | POTE ankyrin domain family, member F | -0.0156131 |
| TNS4 | tensin 4 | -0.0155826 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0154811 |
| TCERG1 | transcription elongation regulator 1 | -0.0154793 |
| FRMD5 | FERM domain containing 5 | -0.0151901 |
| RPS24 | ribosomal protein S24 | -0.0150857 |
| FOSL1 | FOS-like antigen 1 | -0.0150511 |
| PPTC7 | PTC7 protein phosphatase homolog (S. cerevisiae) | -0.0146328 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.0144861 |
| L1CAM | L1 cell adhesion molecule | -0.0143717 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0143466 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.014314 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0139576 |
| HLA-A | major histocompatibility complex, class I, A | -0.0138617 |
| TMSB10 | thymosin beta 10 | -0.0138407 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -0.0137172 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0136594 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0136016 |
| RHOA | ras homolog family member A | -0.0135304 |
| RNF13 | ring finger protein 13 | -0.0134705 |
| RPL28 | ribosomal protein L28 | -0.0134501 |
| RBP1 | retinol binding protein 1, cellular | -0.0134462 |
| KLK10 | kallikrein-related peptidase 10 | -0.0133846 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0133753 |
| ZNF292 | zinc finger protein 292 | -0.0132105 |
| BSG | basigin (Ok blood group) | -0.0131798 |
| RPL27A | ribosomal protein L27a | -0.0130991 |
