| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Goserelin (acetate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | 0.103427 |
| HSPA8 | heat shock 70kDa protein 8 | 0.102733 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.101725 |
| LMO7 | LIM domain 7 | 0.0772704 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0638095 |
| RPS3 | ribosomal protein S3 | 0.0624582 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0612876 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0541151 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0508796 |
| ATXN1 | ataxin 1 | 0.049545 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.046884 |
| NUP50 | nucleoporin 50kDa | 0.046372 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0436747 |
| AHNAK | AHNAK nucleoprotein | 0.0427144 |
| LAMB3 | laminin, beta 3 | 0.0408098 |
| LAMA4 | laminin, alpha 4 | 0.0391739 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0368601 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0351751 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.035116 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0346645 |
| RPS6 | ribosomal protein S6 | 0.0340872 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0340341 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0322132 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0319526 |
| ASPH | aspartate beta-hydroxylase | 0.0309904 |
| VMP1 | vacuole membrane protein 1 | 0.0306237 |
| CTSB | cathepsin B | 0.0302861 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0295812 |
| EZR | ezrin | 0.029487 |
| SGMS2 | sphingomyelin synthase 2 | 0.0292972 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0291594 |
| DST | dystonin | 0.0284837 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0284636 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0283562 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0276162 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0274917 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0274539 |
| FHL2 | four and a half LIM domains 2 | 0.0272359 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0270607 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.026816 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0266494 |
| TMF1 | TATA element modulatory factor 1 | 0.0265811 |
| AREG | amphiregulin | 0.0264225 |
| GOLGB1 | golgin B1 | 0.0258922 |
| RPL14 | ribosomal protein L14 | 0.0253745 |
| EMP1 | epithelial membrane protein 1 | 0.02532 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0245001 |
| FAM107B | family with sequence similarity 107, member B | 0.0244148 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.024059 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0238894 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.0238217 |
| RPL26 | ribosomal protein L26 | 0.0237061 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0236358 |
| VCL | vinculin | 0.0229733 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0226455 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0224906 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0224205 |
| PHF3 | PHD finger protein 3 | 0.0223148 |
| KIF5B | kinesin family member 5B | 0.0218812 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0217702 |
| SEPTIN9 | septin 9 | 0.0216923 |
| IER2 | immediate early response 2 | 0.0214481 |
| RPS12 | ribosomal protein S12 | 0.0214293 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0210876 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0210293 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0209104 |
| FNIP1 | folliculin interacting protein 1 | 0.0207306 |
| CDK13 | cyclin-dependent kinase 13 | 0.0206273 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0204143 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0202383 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0202082 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0201166 |
| MYO5B | myosin VB | 0.019753 |
| PNN | pinin, desmosome associated protein | 0.019733 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0195823 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0195679 |
| SFTPA2 | surfactant protein A2 | 0.0193938 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0193667 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0192954 |
| BRD2 | bromodomain containing 2 | 0.0192318 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.019091 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0189009 |
| SNX9 | sorting nexin 9 | 0.0185711 |
| HMGA2 | high mobility group AT-hook 2 | 0.0185548 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0184584 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0183357 |
| CTTN | cortactin | 0.0182769 |
| VIM | vimentin | 0.0181354 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0179359 |
| RPS27A | ribosomal protein S27a | 0.0176827 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0176499 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0175283 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0174961 |
| DSG2 | desmoglein 2 | 0.0174834 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0173985 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0173157 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0170486 |
| RPS18 | ribosomal protein S18 | 0.0170239 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0169634 |
| RBM12 | RNA binding motif protein 12 | 0.016938 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | -0.242093 |
| PTMA | prothymosin, alpha | -0.221231 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.174484 |
| IER3 | immediate early response 3 | -0.124344 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108421 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0898515 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0895955 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0810134 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0805484 |
| TMSB10 | thymosin beta 10 | -0.0757042 |
| HDAC2 | histone deacetylase 2 | -0.0744279 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0738659 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.068286 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0672818 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0642161 |
| OXR1 | oxidation resistance 1 | -0.0625741 |
| FHIT | fragile histidine triad | -0.0624448 |
| COG5 | component of oligomeric golgi complex 5 | -0.0601574 |
| RPS24 | ribosomal protein S24 | -0.0595143 |
| RAD51B | RAD51 paralog B | -0.059173 |
| RREB1 | ras responsive element binding protein 1 | -0.0555149 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0552213 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0551954 |
| TOP1 | topoisomerase (DNA) I | -0.0540692 |
| PKM | pyruvate kinase, muscle | -0.0523894 |
| SERINC5 | serine incorporator 5 | -0.0512632 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0508665 |
| GPHN | gephyrin | -0.048887 |
| RUNX2 | runt-related transcription factor 2 | -0.0465081 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0454674 |
| PARD3 | par-3 family cell polarity regulator | -0.0397866 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0390968 |
| GDF15 | growth differentiation factor 15 | -0.038835 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0386183 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0381068 |
| AOPEP | aminopeptidase O (putative) | -0.0376755 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0367633 |
| TUBB | tubulin, beta class I | -0.0366689 |
| NEK7 | NIMA-related kinase 7 | -0.0365752 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0365203 |
| RPLP1 | ribosomal protein, large, P1 | -0.0364466 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.036216 |
| MSI2 | musashi RNA-binding protein 2 | -0.0361351 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0359072 |
| FOSL1 | FOS-like antigen 1 | -0.0348643 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0346839 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0344737 |
| RNF43 | ring finger protein 43 | -0.0342707 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0342579 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0337413 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0337236 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0329443 |
| ITGB4 | integrin, beta 4 | -0.0327873 |
| DIAPH2 | diaphanous-related formin 2 | -0.0324473 |
| RCOR1 | REST corepressor 1 | -0.032344 |
| ANXA2 | annexin A2 | -0.0322435 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.032069 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | -0.0320048 |
| ZBTB7C | zinc finger and BTB domain containing 7C | -0.031608 |
| SETD5 | SET domain containing 5 | -0.0314924 |
| ZNRF3 | zinc and ring finger 3 | -0.0314035 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0311061 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | -0.0309584 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.0309531 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.030855 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303667 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.030345 |
| USP3 | ubiquitin specific peptidase 3 | -0.0302388 |
| KRT18 | keratin 18, type I | -0.0300491 |
| SBF2 | SET binding factor 2 | -0.0299909 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0295022 |
| MAP4 | microtubule-associated protein 4 | -0.029316 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0286962 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0285672 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.028404 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0283581 |
| TFRC | transferrin receptor | -0.0282132 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0278875 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0278078 |
| EDAR | ectodysplasin A receptor | -0.0278002 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0276748 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02755 |
| MED13L | mediator complex subunit 13-like | -0.0275217 |
| NUP58 | nucleoporin 58 | -0.0274173 |
| TMEM123 | transmembrane protein 123 | -0.0274148 |
| FAM3C | family with sequence similarity 3, member C | -0.027378 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0270833 |
| FLOT1 | flotillin 1 | -0.0267914 |
| DENND1A | DENN/MADD domain containing 1A | -0.0266495 |
| MTAP | methylthioadenosine phosphorylase | -0.0264482 |
| S100A6 | S100 calcium binding protein A6 | -0.0263458 |
| RAB6A | RAB6A, member RAS oncogene family | -0.026169 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0255401 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0253839 |
| TNPO1 | transportin 1 | -0.0253334 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0252546 |
| TNS3 | tensin 3 | -0.0250809 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0249486 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0245511 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0244342 |
