| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Goserelin (acetate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Goserelin (acetate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.400766 |
| MYO10 | myosin X | 0.14351 |
| INHBA | inhibin, beta A | 0.138234 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.12528 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.086424 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0839402 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0807111 |
| MT2A | metallothionein 2A | 0.0723904 |
| CD44 | CD44 molecule (Indian blood group) | 0.0679333 |
| ASPH | aspartate beta-hydroxylase | 0.0643213 |
| STC1 | stanniocalcin 1 | 0.0595405 |
| HMGA2 | high mobility group AT-hook 2 | 0.0582863 |
| RPS6 | ribosomal protein S6 | 0.0572033 |
| FMNL2 | formin-like 2 | 0.0552462 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0538904 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.047585 |
| CAVIN1 | caveolae associated protein 1 | 0.046923 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0464443 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0456077 |
| RPS12 | ribosomal protein S12 | 0.0451503 |
| B2M | beta-2-microglobulin | 0.0448165 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0444198 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0420219 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0414795 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0389887 |
| NDRG1 | N-myc downstream regulated 1 | 0.0381005 |
| RAI14 | retinoic acid induced 14 | 0.0377964 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0373584 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0366221 |
| VCL | vinculin | 0.0364264 |
| EGFR | epidermal growth factor receptor | 0.036387 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0363509 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0362749 |
| RPS3 | ribosomal protein S3 | 0.0360112 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0354674 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0345724 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0338955 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0317481 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0314283 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0310222 |
| TAPBP | TAP binding protein (tapasin) | 0.0307062 |
| GOLGB1 | golgin B1 | 0.0304734 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0303329 |
| RPS8 | ribosomal protein S8 | 0.0296688 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.028852 |
| MSN | moesin | 0.0283597 |
| RPL26 | ribosomal protein L26 | 0.028141 |
| PRELID2 | PRELI domain containing 2 | 0.02766 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0274501 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0273265 |
| SERINC1 | serine incorporator 1 | 0.0273104 |
| RUNX1 | runt-related transcription factor 1 | 0.0271309 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0270246 |
| SMAD3 | SMAD family member 3 | 0.0269058 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0267264 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0266761 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0262931 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0256801 |
| TMF1 | TATA element modulatory factor 1 | 0.0255068 |
| RASA2 | RAS p21 protein activator 2 | 0.0253871 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0251994 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0246152 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0244284 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0241254 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0235864 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0235324 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0234674 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0234213 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0233168 |
| BRD2 | bromodomain containing 2 | 0.0232364 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0231547 |
| SPAG9 | sperm associated antigen 9 | 0.0230648 |
| SEPTIN9 | septin 9 | 0.0228779 |
| JAK1 | Janus kinase 1 | 0.0228717 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0228562 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0225576 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.02234 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0222918 |
| TOP1 | topoisomerase (DNA) I | 0.0221855 |
| CTSB | cathepsin B | 0.0219956 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0219932 |
| RPL14 | ribosomal protein L14 | 0.0219833 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0216924 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0216029 |
| RPL13A | ribosomal protein L13a | 0.0213201 |
| HDAC9 | histone deacetylase 9 | 0.0212384 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0212155 |
| RPS2 | ribosomal protein S2 | 0.0211768 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.021124 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0208921 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0208505 |
| RPL37A | ribosomal protein L37a | 0.0208418 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.020828 |
| TLN1 | talin 1 | 0.0204912 |
| FN1 | fibronectin 1 | 0.0204869 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0204735 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0201744 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0195845 |
| DUSP6 | dual specificity phosphatase 6 | 0.0193424 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0192739 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.466664 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181639 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.131711 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100803 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.100537 |
| COL1A1 | collagen, type I, alpha 1 | -0.0994341 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0992247 |
| COL1A2 | collagen, type I, alpha 2 | -0.0970364 |
| TMSB10 | thymosin beta 10 | -0.0713271 |
| MMP1 | matrix metallopeptidase 1 | -0.0696795 |
| POTEF | POTE ankyrin domain family, member F | -0.0637976 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0628069 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0604632 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0574129 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0557945 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0535249 |
| TPM4 | tropomyosin 4 | -0.0512874 |
| PKM | pyruvate kinase, muscle | -0.0512622 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0501183 |
| CALU | calumenin | -0.0490101 |
| OXR1 | oxidation resistance 1 | -0.0477072 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0468351 |
| CDH13 | cadherin 13 | -0.0463092 |
| S100A6 | S100 calcium binding protein A6 | -0.0458739 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0458083 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0458023 |
| ENO1 | enolase 1, (alpha) | -0.0452067 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0448613 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0436093 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0422862 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0390585 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0383979 |
| CALD1 | caldesmon 1 | -0.0370647 |
| FBN1 | fibrillin 1 | -0.0358666 |
| UBC | ubiquitin C | -0.0357777 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329858 |
| CALR | calreticulin | -0.0323031 |
| VCAN | versican | -0.0309683 |
| ACTG1 | actin gamma 1 | -0.0297585 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0295207 |
| PRSS23 | protease, serine, 23 | -0.0292942 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0291876 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.02907 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0286928 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0284018 |
| MMP12 | matrix metallopeptidase 12 | -0.0282512 |
| CCND1 | cyclin D1 | -0.0280585 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0277096 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0275475 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.0255573 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0254004 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.025354 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0251831 |
| LOC112694756 | uncharaterized LOC112694756 | -0.024948 |
| EMP1 | epithelial membrane protein 1 | -0.0243731 |
| SEPTIN11 | septin 11 | -0.0243527 |
| INSIG1 | insulin induced gene 1 | -0.0242502 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0240858 |
| CCDC102B | coiled-coil domain containing 102B | -0.0234193 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.02338 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0229722 |
| PRR16 | proline rich 16 | -0.0226943 |
| SEC24D | SEC24 family member D | -0.0226739 |
| CHSY3 | chondroitin sulfate synthase 3 | -0.0225429 |
| TMEM165 | transmembrane protein 165 | -0.0225027 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0224586 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0220628 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0218525 |
| PTEN | phosphatase and tensin homolog | -0.0212774 |
| GNAS | GNAS complex locus | -0.0212732 |
| RPS24 | ribosomal protein S24 | -0.0211011 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0209986 |
| LDHA | lactate dehydrogenase A | -0.0204855 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0202466 |
| WDR45B | WD repeat domain 45B | -0.0201284 |
| ECE1 | endothelin converting enzyme 1 | -0.01991 |
| COL3A1 | collagen, type III, alpha 1 | -0.0198793 |
| NCKAP5 | NCK-associated protein 5 | -0.0198382 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.019803 |
| ARHGAP10 | Rho GTPase activating protein 10 | -0.0194168 |
| ACLY | ATP citrate lyase | -0.0192638 |
| BSG | basigin (Ok blood group) | -0.0192626 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0192326 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0191942 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0190146 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.018929 |
| WASF2 | WAS protein family, member 2 | -0.0187689 |
| EHD2 | EH-domain containing 2 | -0.0186823 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0183347 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0183211 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0181463 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0180554 |
| PRRX1 | paired related homeobox 1 | -0.018012 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0179597 |
| PFN1 | profilin 1 | -0.0179482 |
| NREP | neuronal regeneration related protein | -0.0177798 |
| TRAM1 | translocation associated membrane protein 1 | -0.0177621 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0175666 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0175602 |
| HHIP | hedgehog interacting protein | -0.0175259 |
