H-7-5936 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the H-7-5936 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACOT7 acyl-CoA thioesterase 7
ACTB actin, beta
ADAM10 ADAM metallopeptidase domain 10
ADAM12 ADAM metallopeptidase domain 12
ADAM22 ADAM metallopeptidase domain 22
ADAM8 ADAM metallopeptidase domain 8
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALOX15 arachidonate 15-lipoxygenase
ALS2CL ALS2 C-terminal like
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B9D1 B9 protein domain 1
BAAT bile acid CoA:amino acid N-acyltransferase
C14ORF1 chromosome 14 open reading frame 1
CA5BP1 carbonic anhydrase VB pseudogene 1
CD80 CD80 molecule
COMT catechol-O-methyltransferase
CYB561 cytochrome b561
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DCN decorin
DDA1 DET1 and DDB1 associated 1
DEAF1 DEAF1 transcription factor
DMPK dystrophia myotonica-protein kinase
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DVL3 dishevelled segment polarity protein 3
EIF5A eukaryotic translation initiation factor 5A
ENO1 enolase 1, (alpha)
EXOC7 exocyst complex component 7
FAM134B family with sequence similarity 134, member B
FGF2 fibroblast growth factor 2 (basic)
FKBP1A FK506 binding protein 1A, 12kDa
FSCN1 fascin actin-bundling protein 1
G6PC3 glucose 6 phosphatase, catalytic, 3
GAMT guanidinoacetate N-methyltransferase
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GJA8 gap junction protein, alpha 8, 50kDa
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HES2 hes family bHLH transcription factor 2
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2AI histone cluster 1, H2ai
HMGA1 high mobility group AT-hook 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFITM1 interferon induced transmembrane protein 1
INHA inhibin, alpha
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KHSRP KH-type splicing regulatory protein
KIAA1456 KIAA1456
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LMNA lamin A/C
LTC4S leukotriene C4 synthase
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK14 mitogen-activated protein kinase 14
MPDU1 mannose-P-dolichol utilization defect 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NADK NAD kinase
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRSN2 neurensin 2
NXPH4 neurexophilin 4
PARP3 poly (ADP-ribose) polymerase family, member 3
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD2 programmed cell death 2
PDE10A phosphodiesterase 10A
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
PRB1 proline-rich protein BstNI subfamily 1
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PSENEN presenilin enhancer gamma secretase subunit
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
R3HDM4 R3H domain containing 4
RHOC ras homolog family member C
RNF126P1 ring finger protein 126 pseudogene 1
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPS2 ribosomal protein S2
RRM1 ribonucleotide reductase M1
S100A13 S100 calcium binding protein A13
SCARB1 scavenger receptor class B, member 1
SFTPB surfactant protein B
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRT3 sirtuin 3
SPINK1 serine peptidase inhibitor, Kazal type 1
SS18 synovial sarcoma translocation, chromosome 18
SYNPO synaptopodin
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TCP11L1 t-complex 11, testis-specific-like 1
TMED2 transmembrane emp24 domain trafficking protein 2
TMPRSS6 transmembrane protease, serine 6
TOR1AIP1 torsin A interacting protein 1
TRDMT1 tRNA aspartic acid methyltransferase 1
YIPF5 Yip1 domain family, member 5

decreased expression

Symbol Name
ADNP activity-dependent neuroprotector homeobox
AEN apoptosis enhancing nuclease
AMIGO2 adhesion molecule with Ig-like domain 2
AMOTL2 angiomotin like 2
ARL4A ADP-ribosylation factor-like 4A
ASTE1 asteroid homolog 1 (Drosophila)
BAMBI BMP and activin membrane-bound inhibitor
BCL10 B-cell CLL/lymphoma 10
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BRPF1 bromodomain and PHD finger containing, 1
C14ORF169 chromosome 14 open reading frame 169
CASP8AP2 caspase 8 associated protein 2
CCNL1 cyclin L1
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPC centromere protein C
CHD1 chromodomain helicase DNA binding protein 1
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CLP1 cleavage and polyadenylation factor I subunit 1
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAAF2 dynein, axonemal, assembly factor 2
E2F6 E2F transcription factor 6
EFNA1 ephrin-A1
EFNA4 ephrin-A4
EGR3 early growth response 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FADD Fas (TNFRSF6)-associated via death domain
FANCF Fanconi anemia, complementation group F
FBXO5 F-box protein 5
GCC1 GRIP and coiled-coil domain containing 1
GPATCH1 G patch domain containing 1
HAUS3 HAUS augmin-like complex, subunit 3
HILPDA hypoxia inducible lipid droplet-associated
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HJURP Holliday junction recognition protein
HPS6 Hermansky-Pudlak syndrome 6
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER5 immediate early response 5
IRX5 iroquois homeobox 5
JMJD1C jumonji domain containing 1C
KIAA0232 KIAA0232
KLHL21 kelch-like family member 21
LEMD3 LEM domain containing 3
MAD2L1BP MAD2L1 binding protein
METTL18 methyltransferase like 18
MORC3 MORC family CW-type zinc finger 3
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MSL2 male-specific lethal 2 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NXT1 nuclear transport factor 2-like export factor 1
OSR2 odd-skipped related transciption factor 2
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLK2 polo-like kinase 2
PNRC1 proline-rich nuclear receptor coactivator 1
PPAN peter pan homolog (Drosophila)
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRR15L proline rich 15-like
RBM7 RNA binding motif protein 7
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RGS16 regulator of G-protein signaling 16
RHOB ras homolog family member B
RIPK4 receptor-interacting serine-threonine kinase 4
RND3 Rho family GTPase 3
RNF113A ring finger protein 113A
RNF139 ring finger protein 139
RPP38 ribonuclease P/MRP 38kDa subunit
RSBN1 round spermatid basic protein 1
SALL2 spalt-like transcription factor 2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A2 solute carrier family 38, member 2
SMG8 SMG8 nonsense mediated mRNA decay factor
TBCC tubulin folding cofactor C
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOB1 transducer of ERBB2, 1
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIB1 tribbles pseudokinase 1
TRIM32 tripartite motif containing 32
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
TSKU tsukushi, small leucine rich proteoglycan
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZBED5 zinc finger, BED-type containing 5
ZBTB24 zinc finger and BTB domain containing 24
ZBTB3 zinc finger and BTB domain containing 3
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC8 zinc finger, CCHC domain containing 8
ZFP36 ZFP36 ring finger protein
ZNF14 zinc finger protein 14
ZNF165 zinc finger protein 165
ZNF217 zinc finger protein 217
ZNF274 zinc finger protein 274
ZNF443 zinc finger protein 443
ZNF7 zinc finger protein 7
ZNF84 zinc finger protein 84