| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the H-7-5963 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABHD6 | abhydrolase domain containing 6 |
| AGER | advanced glycosylation end product-specific receptor |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| ALOX5 | arachidonate 5-lipoxygenase |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARMC4 | armadillo repeat containing 4 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATG10 | autophagy related 10 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 |
| ATRNL1 | attractin-like 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BMP1 | bone morphogenetic protein 1 |
| BTNL3 | butyrophilin-like 3 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA1 | carbonic anhydrase I |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD1A | CD1a molecule |
| CD52 | CD52 molecule |
| CD8A | CD8a molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| COL5A1 | collagen, type V, alpha 1 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DIO2 | deiodinase, iodothyronine, type II |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DMTN | dematin actin binding protein |
| ESR1 | estrogen receptor 1 |
| FBXO11 | F-box protein 11 |
| FLJ11292 | |
| FN1 | fibronectin 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| HABP4 | hyaluronan binding protein 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HES2 | hes family bHLH transcription factor 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLF | hepatic leukemia factor |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HRH3 | histamine receptor H3 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KSR1 | kinase suppressor of ras 1 |
| LAMB4 | laminin, beta 4 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAGEA1 | melanoma antigen family A1 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED25 | mediator complex subunit 25 |
| MTMR1 | myotubularin related protein 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDRG2 | NDRG family member 2 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| ONECUT2 | one cut homeobox 2 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLSCR4 | phospholipid scramblase 4 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PON3 | paraoxonase 3 |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RAI2 | retinoic acid induced 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RPL23 | ribosomal protein L23 |
| S100B | S100 calcium binding protein B |
| SAMD9 | sterile alpha motif domain containing 9 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOX2 | SRY (sex determining region Y)-box 2 |
| TCF3 | transcription factor 3 |
| TCTN2 | tectonic family member 2 |
| TEF | thyrotrophic embryonic factor |
| TLE2 | transducin-like enhancer of split 2 |
| TLN2 | talin 2 |
| TPMT | thiopurine S-methyltransferase |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| USP46 | ubiquitin specific peptidase 46 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| YY1 | YY1 transcription factor |
| Symbol | Name |
|---|---|
| AMOTL2 | angiomotin like 2 |
| ARL4A | ADP-ribosylation factor-like 4A |
| ARMC7 | armadillo repeat containing 7 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BCL10 | B-cell CLL/lymphoma 10 |
| BRD1 | bromodomain containing 1 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CEP76 | centrosomal protein 76kDa |
| CHD1 | chromodomain helicase DNA binding protein 1 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLK1 | CDC-like kinase 1 |
| CLK4 | CDC-like kinase 4 |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| DCLRE1B | DNA cross-link repair 1B |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNMBP | dynamin binding protein |
| E2F6 | E2F transcription factor 6 |
| EFNA1 | ephrin-A1 |
| EFNA4 | ephrin-A4 |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM46A | family with sequence similarity 46, member A |
| FBXO5 | F-box protein 5 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GPATCH1 | G patch domain containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HJURP | Holliday junction recognition protein |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IER5 | immediate early response 5 |
| IRX5 | iroquois homeobox 5 |
| JMJD1C | jumonji domain containing 1C |
| LEMD3 | LEM domain containing 3 |
| MAD2L1BP | MAD2L1 binding protein |
| METTL18 | methyltransferase like 18 |
| MGA | MGA, MAX dimerization protein |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NDC80 | NDC80 kinetochore complex component |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OSR2 | odd-skipped related transciption factor 2 |
| OXSM | 3-oxoacyl-ACP synthase, mitochondrial |
| PCGF1 | polycomb group ring finger 1 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PLK2 | polo-like kinase 2 |
| PPAN | peter pan homolog (Drosophila) |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRR15L | proline rich 15-like |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RGS16 | regulator of G-protein signaling 16 |
| RHOB | ras homolog family member B |
| RND3 | Rho family GTPase 3 |
| RNF113A | ring finger protein 113A |
| RNF139 | ring finger protein 139 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| RSBN1 | round spermatid basic protein 1 |
| SIRT1 | sirtuin 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SMG8 | SMG8 nonsense mediated mRNA decay factor |
| SPATA2L | spermatogenesis associated 2-like |
| TAF5 | TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa |
| TBCC | tubulin folding cofactor C |
| TBK1 | TANK-binding kinase 1 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THAP11 | THAP domain containing 11 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A |
| TOB1 | transducer of ERBB2, 1 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIM32 | tripartite motif containing 32 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSC22D1 | TSC22 domain family, member 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZBED5 | zinc finger, BED-type containing 5 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF165 | zinc finger protein 165 |
| ZNF217 | zinc finger protein 217 |
| ZNF248 | zinc finger protein 248 |
| ZNF430 | zinc finger protein 430 |
| ZNF443 | zinc finger protein 443 |
| ZNF7 | zinc finger protein 7 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
