| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/440005 |
| Similar Terms | |
| Downloads & Tools |
198 proteins with high or low expression in H-Arg(NO2)-OH relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH8 | myosin, heavy chain 8, skeletal muscle, perinatal | 7.76 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | 7.64 |
| COL1A2 | collagen, type I, alpha 2 | 7.35 |
| MYH1 | myosin, heavy chain 1, skeletal muscle, adult | 7.33 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 7.22 |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta | 7.09 |
| CA3 | carbonic anhydrase III | 7.07 |
| PYGM | phosphorylase, glycogen, muscle | 6.92 |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) | 6.71 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 6.59 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 6.41 |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) | 6.3 |
| TPM1 | tropomyosin 1 (alpha) | 6.3 |
| MYOM2 | myomesin 2 | 6.25 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 6.19 |
| MYH6 | myosin, heavy chain 6, cardiac muscle, alpha | 6.08 |
| TNNC2 | troponin C type 2 (fast) | 5.71 |
| MYBPC2 | myosin binding protein C, fast type | 5.63 |
| ACTN2 | actinin, alpha 2 | 5.47 |
| ANKRD36 | ankyrin repeat domain 36 | 5.07 |
| MYH4 | myosin, heavy chain 4, skeletal muscle | 4.58 |
| MYBPC1 | myosin binding protein C, slow type | 4.27 |
| GSTM4 | glutathione S-transferase mu 4 | 4.17 |
| FBP2 | fructose-1,6-bisphosphatase 2 | 4.16 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | 3.5 |
| NEB | nebulin | 3.26 |
| GSTM5 | glutathione S-transferase mu 5 | 3.21 |
| CKM | creatine kinase, muscle | 3.2 |
| MYH7B | myosin, heavy chain 7B, cardiac muscle, beta | 3.14 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 2.6 |
| MSH5 | mutS homolog 5 | 2.58 |
| TTN | titin | 2.55 |
| TPM2 | tropomyosin 2 (beta) | 2.38 |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) | 2.34 |
| DES | desmin | 2.18 |
| TPM3 | tropomyosin 3 | 2.01 |
| AMPD1 | adenosine monophosphate deaminase 1 | 1.97 |
| ENO3 | enolase 3 (beta, muscle) | 1.74 |
| NDRG2 | NDRG family member 2 | 1.52 |
| HBA1 | hemoglobin, alpha 1 | 1.35 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | 1.26 |
| PKM | pyruvate kinase, muscle | 1.22 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 1.21 |
| KSR2 | kinase suppressor of ras 2 | 1.15 |
| BIRC5 | baculoviral IAP repeat containing 5 | 1.1 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 1.09 |
| ACTA1 | actin, alpha 1, skeletal muscle | 1.08 |
| FHL1 | four and a half LIM domains 1 | 1.02 |
| MCM8 | minichromosome maintenance complex component 8 | 0.9 |
| AK1 | adenylate kinase 1 | 0.89 |
| VIM | vimentin | 0.79 |
| TRMT61A | tRNA methyltransferase 61A | 0.74 |
| PGM1 | phosphoglucomutase 1 | 0.73 |
| POF1B | premature ovarian failure, 1B | 0.72 |
| TMOD2 | tropomodulin 2 (neuronal) | 0.72 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.71 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.69 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.64 |
| CCDC150 | coiled-coil domain containing 150 | 0.64 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit | 0.63 |
| BCOR | BCL6 corepressor | 0.62 |
| REPIN1 | replication initiator 1 | 0.6 |
| TRERF1 | transcriptional regulating factor 1 | 0.6 |
| ACYP2 | acylphosphatase 2, muscle type | 0.57 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 0.54 |
| LRRC57 | leucine rich repeat containing 57 | 0.51 |
| GRB14 | growth factor receptor-bound protein 14 | 0.5 |
| CHD8 | chromodomain helicase DNA binding protein 8 | 0.49 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | 0.48 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.46 |
| SH2B2 | SH2B adaptor protein 2 | 0.46 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | 0.46 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | 0.42 |
| FLNC | filamin C, gamma | 0.42 |
| RPL26 | ribosomal protein L26 | 0.41 |
| TMEM222 | transmembrane protein 222 | 0.41 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.41 |
| SET | SET nuclear proto-oncogene | 0.41 |
| BCL2L12 | BCL2-like 12 (proline rich) | 0.39 |
| RNF146 | ring finger protein 146 | 0.38 |
| RNF145 | ring finger protein 145 | 0.38 |
| BAIAP2 | BAI1-associated protein 2 | 0.38 |
| TBC1D22B | TBC1 domain family, member 22B | 0.37 |
| ACTL8 | actin-like 8 | 0.37 |
| ARHGEF35 | Rho guanine nucleotide exchange factor (GEF) 35 | 0.36 |
| FAM185A | family with sequence similarity 185, member A | 0.35 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 0.35 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 | 0.34 |
| KIAA1324L | KIAA1324-like | 0.34 |
| DUSP23 | dual specificity phosphatase 23 | 0.34 |
| GATD1 | glutamine amidotransferase class 1 domain containing 1 | 0.34 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.33 |
| TTC39A | tetratricopeptide repeat domain 39A | 0.33 |
| PALB2 | partner and localizer of BRCA2 | 0.33 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.32 |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like | 0.32 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.32 |
| B2M | beta-2-microglobulin | 0.32 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.32 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -0.7 |
| SLC35B3 | solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 | -0.7 |
| C4BPA | complement component 4 binding protein, alpha | -0.68 |
| RAB40C | RAB40C, member RAS oncogene family | -0.64 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.61 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | -0.6 |
| PIGX | phosphatidylinositol glycan anchor biosynthesis, class X | -0.59 |
| PTPDC1 | protein tyrosine phosphatase domain containing 1 | -0.59 |
| IRF9 | interferon regulatory factor 9 | -0.59 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | -0.58 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.58 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -0.57 |
| LRP1 | low density lipoprotein receptor-related protein 1 | -0.55 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.53 |
| BLOC1S3 | biogenesis of lysosomal organelles complex-1, subunit 3 | -0.51 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | -0.51 |
| SLC41A3 | solute carrier family 41, member 3 | -0.5 |
| DUSP14 | dual specificity phosphatase 14 | -0.49 |
| MFSD14B | major facilitator superfamily domain containing 14B | -0.47 |
| ALG10B | ALG10B, alpha-1,2-glucosyltransferase | -0.45 |
| CRCP | CGRP receptor component | -0.45 |
| ERICH5 | glutamate-rich 5 | -0.45 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.45 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.45 |
| ZC3H6 | zinc finger CCCH-type containing 6 | -0.44 |
| ECM1 | extracellular matrix protein 1 | -0.44 |
| MED18 | mediator complex subunit 18 | -0.43 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.43 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.43 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | -0.43 |
| NAA38 | N(alpha)-acetyltransferase 38, NatC auxiliary subunit | -0.42 |
| POM121C | POM121 transmembrane nucleoporin C | -0.41 |
| LRRK1 | leucine-rich repeat kinase 1 | -0.41 |
| LINS1 | lines homolog 1 | -0.41 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.41 |
| MRPL33 | mitochondrial ribosomal protein L33 | -0.4 |
| TM2D3 | TM2 domain containing 3 | -0.39 |
| ATP13A2 | ATPase type 13A2 | -0.39 |
| ATF3 | activating transcription factor 3 | -0.39 |
| DNAH6 | dynein, axonemal, heavy chain 6 | -0.39 |
| GINM1 | glycoprotein integral membrane 1 | -0.37 |
| MED8 | mediator complex subunit 8 | -0.37 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | -0.37 |
| JUN | jun proto-oncogene | -0.37 |
| RBMXL1 | RNA binding motif protein, X-linked-like 1 | -0.37 |
| OSTF1 | osteoclast stimulating factor 1 | -0.37 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.36 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.36 |
| MRPL51 | mitochondrial ribosomal protein L51 | -0.36 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.36 |
| TMPO | thymopoietin | -0.36 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.35 |
| PLCD1 | phospholipase C, delta 1 | -0.35 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.35 |
| KIAA1210 | KIAA1210 | -0.35 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.35 |
| RNF126 | ring finger protein 126 | -0.34 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 | -0.34 |
| RAB11FIP4 | RAB11 family interacting protein 4 (class II) | -0.34 |
| NPHP1 | nephronophthisis 1 (juvenile) | -0.34 |
| AGA | aspartylglucosaminidase | -0.34 |
| INPP5J | inositol polyphosphate-5-phosphatase J | -0.34 |
| MT-ND4 | NADH dehydrogenase, subunit 4 (complex I) | -0.33 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like | -0.33 |
| REEP1 | receptor accessory protein 1 | -0.33 |
| CSNK1G2 | casein kinase 1, gamma 2 | -0.33 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.33 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa | -0.33 |
| DOP1A | DOP1 leucine zipper like protein A | -0.32 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | -0.32 |
| C1D | C1D nuclear receptor corepressor | -0.32 |
| ZFP36 | ZFP36 ring finger protein | -0.32 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.32 |
| FTL | ferritin, light polypeptide | -0.32 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.32 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.32 |
| GDF15 | growth differentiation factor 15 | -0.31 |
| MRPS33 | mitochondrial ribosomal protein S33 | -0.31 |
| MINDY4 | MINDY lysine 48 deubiquitinase 4 | -0.31 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.31 |
| ABRAXAS1 | abraxas 1, BRCA1 A complex subunit | -0.31 |
| CADPS | Ca++-dependent secretion activator | -0.31 |
| RHOD | ras homolog family member D | -0.31 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.31 |
| ADCK1 | aarF domain containing kinase 1 | -0.31 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.31 |
| ZNF337 | zinc finger protein 337 | -0.31 |
| FAT4 | FAT atypical cadherin 4 | -0.31 |
| MYO15A | myosin XVA | -0.3 |
| NAA80 | N-alpha-acetyltransferase 80, NatH catalytic subunit | -0.3 |
| KLHL22 | kelch-like family member 22 | -0.3 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | -0.3 |
| SUMF2 | sulfatase modifying factor 2 | -0.3 |
| METTL25 | methyltransferase like 25 | -0.3 |
| DOCK3 | dedicator of cytokinesis 3 | -0.3 |
| CDA | cytidine deaminase | -0.3 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | -0.3 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.3 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | -0.29 |
