H2AFZ Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description H2A histone family, member Z|Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3015)
External Link http://www.ncbi.nlm.nih.gov/gene/3015
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Genes

424 interacting proteins for H2AFZ from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABRA actin binding Rho activating protein
ACAA2 acetyl-CoA acyltransferase 2
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
ACTC1 actin, alpha, cardiac muscle 1
ACTL6A actin-like 6A
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADNP activity-dependent neuroprotector homeobox
AGK acylglycerol kinase
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AJAP1 adherens junctions associated protein 1
ALPK3 alpha-kinase 3
ANLN anillin, actin binding protein
AP4B1 adaptor-related protein complex 4, beta 1 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARG1 arginase 1
ARID4B AT rich interactive domain 4B (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ASB16 ankyrin repeat and SOCS box containing 16
ASB9 ankyrin repeat and SOCS box containing 9
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATM ATM serine/threonine kinase
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAHCC1 BAH domain and coiled-coil containing 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL9 B-cell CLL/lymphoma 9
BCL9L B-cell CLL/lymphoma 9-like
BPTF bromodomain PHD finger transcription factor
BRWD1 bromodomain and WD repeat domain containing 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C20ORF57 chromosome 20 open reading frame 57
C2ORF16 chromosome 2 open reading frame 16
C4A complement component 4A (Rodgers blood group)
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CALCOCO2 calcium binding and coiled-coil domain 2
CALD1 caldesmon 1
CBFB core-binding factor, beta subunit
CCM2L cerebral cavernous malformation 2-like
CCNB1 cyclin B1
CCND1 cyclin D1
CDC26 cell division cycle 26
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDV3 CDV3 homolog (mouse)
CENPA centromere protein A
CENPV centromere protein V
CEP170 centrosomal protein 170kDa
CEP55 centrosomal protein 55kDa
CFL1 cofilin 1 (non-muscle)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHD1L chromodomain helicase DNA binding protein 1-like
CKAP4 cytoskeleton-associated protein 4
CLEC11A C-type lectin domain family 11, member A
CLSTN1 calsyntenin 1
CNOT11 CCR4-NOT transcription complex, subunit 11
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTN5 contactin 5
COPRS coordinator of PRMT5, differentiation stimulator
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
CROCC ciliary rootlet coiled-coil, rootletin
CSF1 colony stimulating factor 1 (macrophage)
CSMD2 CUB and Sushi multiple domains 2
CTBP1 C-terminal binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTR9 CTR9, Paf1/RNA polymerase II complex component
CYBA cytochrome b-245, alpha polypeptide
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DENND3 DENN/MADD domain containing 3
DENND6B DENN/MADD domain containing 6B
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DMAP1 DNA methyltransferase 1 associated protein 1
DNAH8 dynein, axonemal, heavy chain 8
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNLRB1 dynein, light chain, roadblock-type 1
EED embryonic ectoderm development
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
EP400 E1A binding protein p400
EPC1 enhancer of polycomb homolog 1 (Drosophila)
ERBB2IP erbb2 interacting protein
ERP44 endoplasmic reticulum protein 44
ETV3 ets variant 3
ETV6 ets variant 6
EXOSC1 exosome component 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FAF2 Fas associated factor family member 2
FAM117B family with sequence similarity 117, member B
FANCM Fanconi anemia, complementation group M
FASTKD1 FAST kinase domains 1
FERMT3 fermitin family member 3
FH fumarate hydratase
FLNA filamin A, alpha
FN1 fibronectin 1
FOSL2 FOS-like antigen 2
FOXC2 forkhead box C2
FRMD6 FERM domain containing 6
FRMPD4 FERM and PDZ domain containing 4
FZD10 frizzled class receptor 10
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GEMIN5 gem (nuclear organelle) associated protein 5
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR158 G protein-coupled receptor 158
GSK3B glycogen synthase kinase 3 beta
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HCFC2 host cell factor C2
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HIRA histone cell cycle regulator
HIST1H1A histone cluster 1, H1a
HIST1H2AB histone cluster 1, H2ab
HIST1H2BB histone cluster 1, H2bb
HIST1H2BK histone cluster 1, H2bk
HIST1H2BM histone cluster 1, H2bm
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST1H4G histone cluster 1, H4g
HIST2H2AA4 histone cluster 2, H2aa4
HIST2H3A histone cluster 2, H3a
HIST3H2A histone cluster 3, H2a
HK1 hexokinase 1
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HOXA10 homeobox A10
HOXB5 homeobox B5
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSPB1 heat shock 27kDa protein 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL16 interleukin 16
IL1B interleukin 1, beta
IMMT inner membrane protein, mitochondrial
INCENP inner centromere protein antigens 135/155kDa
ING3 inhibitor of growth family, member 3
INO80C INO80 complex subunit C
INSM1 insulinoma-associated 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
JUN jun proto-oncogene
KALRN kalirin, RhoGEF kinase
KANK2 KN motif and ankyrin repeat domains 2
KARS lysyl-tRNA synthetase
KAT5 K(lysine) acetyltransferase 5
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3
KDM6B lysine (K)-specific demethylase 6B
KIAA0319 KIAA0319
KIAA0922 KIAA0922
KIAA2026 KIAA2026
KIF12 kinesin family member 12
KIF20B kinesin family member 20B
KLF10 Kruppel-like factor 10
KMT2A lysine (K)-specific methyltransferase 2A
KMT2D lysine (K)-specific methyltransferase 2D
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA3 karyopherin alpha 3 (importin alpha 4)
LBX2 ladybird homeobox 2
LCN12 lipocalin 12
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS7B lectin, galactoside-binding, soluble, 7B
LIMS1 LIM and senescent cell antigen-like domains 1
LMNA lamin A/C
LOX lysyl oxidase
LRP1B low density lipoprotein receptor-related protein 1B
LUZP1 leucine zipper protein 1
MAATS1 MYCBP-associated, testis expressed 1
MAGEB10 melanoma antigen family B10
MAGEC1 melanoma antigen family C1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP1A microtubule-associated protein 1A
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP7D1 MAP7 domain containing 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAST4 microtubule associated serine/threonine kinase family member 4
MATN4 matrilin 4
MAX MYC associated factor X
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
MCM4 minichromosome maintenance complex component 4
MCTP2 multiple C2 domains, transmembrane 2
MEAF6 MYST/Esa1-associated factor 6
MED12L mediator complex subunit 12-like
MEN1 multiple endocrine neoplasia I
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKL1 megakaryoblastic leukemia (translocation) 1
MORF4L1 mortality factor 4 like 1
MRGBP MRG/MORF4L binding protein
MRPL14 mitochondrial ribosomal protein L14
MTRF1 mitochondrial translational release factor 1
MUC3A mucin 3A, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO18A myosin XVIIIA
MYO1D myosin ID
NAIP NLR family, apoptosis inhibitory protein
NAV3 neuron navigator 3
NCAPD3 non-SMC condensin II complex, subunit D3
NCAPG2 non-SMC condensin II complex, subunit G2
NCAPH non-SMC condensin I complex, subunit H
NCAPH2 non-SMC condensin II complex, subunit H2
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NFIL3 nuclear factor, interleukin 3 regulated
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOMO2 NODAL modulator 2
NPC1L1 NPC1-like 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR1 natriuretic peptide receptor 1
NPTX2 neuronal pentraxin II
NRD1 nardilysin (N-arginine dibasic convertase)
NUP98 nucleoporin 98kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OPHN1 oligophrenin 1
OTUD4 OTU deubiquitinase 4
PADI2 peptidyl arginine deiminase, type II
PALD1 phosphatase domain containing, paladin 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PCBP2 poly(rC) binding protein 2
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PDLIM4 PDZ and LIM domain 4
PDS5B PDS5 cohesin associated factor B
PFDN2 prefoldin subunit 2
PGD phosphogluconate dehydrogenase
PHF20 PHD finger protein 20
PHF6 PHD finger protein 6
PITX2 paired-like homeodomain 2
PKM pyruvate kinase, muscle
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PML promyelocytic leukemia
POLG polymerase (DNA directed), gamma
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPA2 pyrophosphatase (inorganic) 2
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRDM9 PR domain containing 9
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRG4 proteoglycan 4
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCDBP protein kinase C, delta binding protein
PRMT5 protein arginine methyltransferase 5
PRR11 proline rich 11
PRRC2A proline-rich coiled-coil 2A
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTBP1 polypyrimidine tract binding protein 1
PYGL phosphorylase, glycogen, liver
PYGO1 pygopus family PHD finger 1
PYGO2 pygopus family PHD finger 2
QPCTL glutaminyl-peptide cyclotransferase-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD50 RAD50 homolog (S. cerevisiae)
RAG1 recombination activating gene 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RARG retinoic acid receptor, gamma
RB1 retinoblastoma 1
RBBP4 retinoblastoma binding protein 4
RBBP5 retinoblastoma binding protein 5
RBBP7 retinoblastoma binding protein 7
RBFA ribosome binding factor A (putative)
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM10 RNA binding motif protein 10
RBM39 RNA binding motif protein 39
RFX7 regulatory factor X, 7
RIMS2 regulating synaptic membrane exocytosis 2
RPA3 replication protein A3, 14kDa
RPL26L1 ribosomal protein L26-like 1
RPP30 ribonuclease P/MRP 30kDa subunit
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPS16 ribosomal protein S16
RPS2 ribosomal protein S2
RPS21 ribosomal protein S21
RPS27L ribosomal protein S27-like
RRM1 ribonucleotide reductase M1
RRP1B ribosomal RNA processing 1B
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SACS sacsin molecular chaperone
SAMD9L sterile alpha motif domain containing 9-like
SAP130 Sin3A-associated protein, 130kDa
SAP18 Sin3A-associated protein, 18kDa
SAP30 Sin3A-associated protein, 30kDa
SAP30BP SAP30 binding protein
SAP30L SAP30-like
SBNO2 strawberry notch homolog 2 (Drosophila)
SDF4 stromal cell derived factor 4
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC11C SEC11 homolog C (S. cerevisiae)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SET SET nuclear proto-oncogene
SETD8 SET domain containing (lysine methyltransferase) 8
SETX senataxin
SGOL2 shugoshin-like 2 (S. pombe)
SH3RF1 SH3 domain containing ring finger 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHE Src homology 2 domain containing E
SIN3A SIN3 transcription regulator family member A
SIN3B SIN3 transcription regulator family member B
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT1 sirtuin 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMC2 structural maintenance of chromosomes 2
SMC6 structural maintenance of chromosomes 6
SMTN smoothelin
SMYD4 SET and MYND domain containing 4
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPF small nuclear ribonucleoprotein polypeptide F
SNX19 sorting nexin 19
SQRDL sulfide quinone reductase-like (yeast)
SRCAP Snf2-related CREBBP activator protein
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
SUCLG1 succinate-CoA ligase, alpha subunit
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae)
SUMO1 small ubiquitin-like modifier 1
SUMO3 small ubiquitin-like modifier 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYNE1 spectrin repeat containing, nuclear envelope 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TBL2 transducin (beta)-like 2
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDG thymine-DNA glycosylase
TENM2 teneurin transmembrane protein 2
TEX2 testis expressed 2
TMPRSS11A transmembrane protease, serine 11A
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNPO1 transportin 1
TNR tenascin R
TNS2 tensin 2
TOP2A topoisomerase (DNA) II alpha 170kDa
TPH1 tryptophan hydroxylase 1
TPP1 tripeptidyl peptidase I
TRABD2A TraB domain containing 2A
TRAK1 trafficking protein, kinesin binding 1
TRAP1 TNF receptor-associated protein 1
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRRAP transformation/transcription domain-associated protein
TUBA4A tubulin, alpha 4a
TUBB3 tubulin, beta 3 class III
TUBB6 tubulin, beta 6 class V
TUFM Tu translation elongation factor, mitochondrial
TXN thioredoxin
UBA1 ubiquitin-like modifier activating enzyme 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
UBD ubiquitin D
UBTF upstream binding transcription factor, RNA polymerase I
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
USP10 ubiquitin specific peptidase 10
USP36 ubiquitin specific peptidase 36
USP48 ubiquitin specific peptidase 48
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WDFY3 WD repeat and FYVE domain containing 3
WDR77 WD repeat domain 77
WIPF1 WAS/WASL interacting protein family, member 1
WWOX WW domain containing oxidoreductase
XKRX XK, Kell blood group complex subunit-related, X-linked
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XYLT1 xylosyltransferase I
YAF2 YY1 associated factor 2
YEATS4 YEATS domain containing 4
ZBTB1 zinc finger and BTB domain containing 1
ZBTB18 zinc finger and BTB domain containing 18
ZBTB40 zinc finger and BTB domain containing 40
ZC3H18 zinc finger CCCH-type containing 18
ZC3H7B zinc finger CCCH-type containing 7B
ZFHX3 zinc finger homeobox 3
ZNF106 zinc finger protein 106
ZNF354B zinc finger protein 354B
ZNF541 zinc finger protein 541
ZNF586 zinc finger protein 586
ZNF703 zinc finger protein 703
ZNF740 zinc finger protein 740
ZNHIT1 zinc finger, HIT-type containing 1
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1