HCC1500 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description disease: primary ductal carcinoma (Cell Line Ontology, CLO_0003639)
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Genes

343 genes mutated in the HCC1500 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A1BG alpha-1-B glycoprotein
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACTRT3 actin-related protein T3
ADAM20 ADAM metallopeptidase domain 20
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADCY9 adenylate cyclase 9
ADGB androglobin
ADGRF5 adhesion G protein-coupled receptor F5
AHNAK2 AHNAK nucleoprotein 2
AIM1 absent in melanoma 1
AKAP13 A kinase (PRKA) anchor protein 13
AKR1C1 aldo-keto reductase family 1, member C1
ALG8 ALG8, alpha-1,3-glucosyltransferase
ALKBH8 alkB, alkylation repair homolog 8 (E. coli)
ANKHD1 ankyrin repeat and KH domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKLE1 ankyrin repeat and LEM domain containing 1
ANKRD16 ankyrin repeat domain 16
ANKRD36C ankyrin repeat domain 36C
ANKRD53 ankyrin repeat domain 53
ANKRD55 ankyrin repeat domain 55
ANKRD62 ankyrin repeat domain 62
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANO8 anoctamin 8
ARHGAP24 Rho GTPase activating protein 24
ARSJ arylsulfatase family, member J
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASIC1 acid sensing (proton gated) ion channel 1
ATM ATM serine/threonine kinase
ATP13A1 ATPase type 13A1
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL10 B-cell CLL/lymphoma 10
BLZF1 basic leucine zipper nuclear factor 1
BMP2K BMP2 inducible kinase
C5 complement component 5
CALR calreticulin
CAPN11 calpain 11
CAPN2 calpain 2, (m/II) large subunit
CATSPER1 cation channel, sperm associated 1
CD320 CD320 molecule
CD5 CD5 molecule
CD84 CD84 molecule
CDC26 cell division cycle 26
CDNF cerebral dopamine neurotrophic factor
CENPT centromere protein T
CFAP43 cilia and flagella associated protein 43
CFAP45 cilia and flagella associated protein 45
CFAP97 cilia and flagella associated protein 97
CGB1 chorionic gonadotropin, beta polypeptide 1
CHD4 chromodomain helicase DNA binding protein 4
CHRM3 cholinergic receptor, muscarinic 3
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CLEC10A C-type lectin domain family 10, member A
CMTR2 cap methyltransferase 2
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
COL27A1 collagen, type XXVII, alpha 1
COL4A4 collagen, type IV, alpha 4
CPT1C carnitine palmitoyltransferase 1C
CRB2 crumbs family member 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSMD1 CUB and Sushi multiple domains 1
CSMD3 CUB and Sushi multiple domains 3
CTAGE5 CTAGE family, member 5
CTNNBL1 catenin, beta like 1
CUBN cubilin (intrinsic factor-cobalamin receptor)
CUL9 cullin 9
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
CYTH3 cytohesin 3
DCT dopachrome tautomerase
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DEDD death effector domain containing
DGCR2 DiGeorge syndrome critical region gene 2
DHCR24 24-dehydrocholesterol reductase
DISP1 dispatched homolog 1 (Drosophila)
DMRT2 doublesex and mab-3 related transcription factor 2
DNAAF3 dynein, axonemal, assembly factor 3
DNAH11 dynein, axonemal, heavy chain 11
DNAH17 dynein, axonemal, heavy chain 17
DNAH5 dynein, axonemal, heavy chain 5
DNAH7 dynein, axonemal, heavy chain 7
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYM dymeclin
E2F7 E2F transcription factor 7
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EML2 echinoderm microtubule associated protein like 2
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EXPH5 exophilin 5
F5 coagulation factor V (proaccelerin, labile factor)
FAM160B1 family with sequence similarity 160, member B1
FAM170A family with sequence similarity 170, member A
FAM20A family with sequence similarity 20, member A
FAM78B family with sequence similarity 78, member B
FANCM Fanconi anemia, complementation group M
FBXO18 F-box protein, helicase, 18
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD5 FYVE, RhoGEF and PH domain containing 5
FKBP1C FK506 binding protein 1C
FLG filaggrin
FMN2 formin 2
FMO6P flavin containing monooxygenase 6 pseudogene
FOXP2 forkhead box P2
FRS3 fibroblast growth factor receptor substrate 3
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GAP43 growth associated protein 43
GEM GTP binding protein overexpressed in skeletal muscle
GFI1B growth factor independent 1B transcription repressor
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GINS1 GINS complex subunit 1 (Psf1 homolog)
GLYATL1 glycine-N-acyltransferase-like 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GOLGA6L10 golgin A6 family-like 10
GPATCH8 G patch domain containing 8
GPC4 glypican 4
GPHA2 glycoprotein hormone alpha 2
GPR148 G protein-coupled receptor 148
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GRM4 glutamate receptor, metabotropic 4
HAP1 huntingtin-associated protein 1
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HIST1H3B histone cluster 1, H3b
HNRNPK heterogeneous nuclear ribonucleoprotein K
HPCA hippocalcin
HRNR hornerin
HSPA14 heat shock 70kDa protein 14
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFI44L interferon-induced protein 44-like
IL6 interleukin 6
INTS8 integrator complex subunit 8
IPO8 importin 8
IRF2BP2 interferon regulatory factor 2 binding protein 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
IZUMO2 IZUMO family member 2
JUP junction plakoglobin
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0195 KIAA0195
KIAA1211 KIAA1211
KIAA1429 KIAA1429
KIAA1671 KIAA1671
KIAA2018 KIAA2018
KIDINS220 kinase D-interacting substrate, 220kDa
KIF18B kinesin family member 18B
KIF21A kinesin family member 21A
KIFAP3 kinesin-associated protein 3
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLK15 kallikrein-related peptidase 15
KMT2C lysine (K)-specific methyltransferase 2C
KRT4 keratin 4, type II
KRT6C keratin 6C, type II
KRT77 keratin 77, type II
KRT86 keratin 86, type II
KRTAP10-2 keratin associated protein 10-2
KRTAP4-2 keratin associated protein 4-2
KRTAP4-6 keratin associated protein 4-6
KRTAP9-2 keratin associated protein 9-2
LGALS9C lectin, galactoside-binding, soluble, 9C
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOXL3 lysyl oxidase-like 3
LPA lipoprotein, Lp(a)
LRP5 low density lipoprotein receptor-related protein 5
LRRC43 leucine rich repeat containing 43
LYZL1 lysozyme-like 1
LZTS2 leucine zipper, putative tumor suppressor 2
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor
MAT2B methionine adenosyltransferase II, beta
MATN2 matrilin 2
MCM10 minichromosome maintenance complex component 10
MEF2A myocyte enhancer factor 2A
MEGF8 multiple EGF-like-domains 8
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MIEF1 mitochondrial elongation factor 1
MMP20 matrix metallopeptidase 20
MNMIP1 manchette microtubule inner protein 1
MORC1 MORC family CW-type zinc finger 1
MRFAP1L1 Morf4 family associated protein 1-like 1
MSL3 male-specific lethal 3 homolog (Drosophila)
MTMR7 myotubularin related protein 7
MUC12 mucin 12, cell surface associated
MUC17 mucin 17, cell surface associated
MUC4 mucin 4, cell surface associated
MVK mevalonate kinase
MYBPC2 myosin binding protein C, fast type
MYO9B myosin IXB
NAMPT nicotinamide phosphoribosyltransferase
NBR1 neighbor of BRCA1 gene 1
NCOR2 nuclear receptor corepressor 2
NEB nebulin
NEBL nebulette
NOXO1 NADPH oxidase organizer 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NUP205 nucleoporin 205kDa
NXN nucleoredoxin
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1
OR4A13P olfactory receptor, family 4, subfamily A, member 13 pseudogene
OR4A16 olfactory receptor, family 4, subfamily A, member 16
OR5AC2 olfactory receptor, family 5, subfamily AC, member 2
OR5H14 olfactory receptor, family 5, subfamily H, member 14
OR6K3 olfactory receptor, family 6, subfamily K, member 3
OTOG otogelin
P3H3 prolyl 3-hydroxylase 3
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PASD1 PAS domain containing 1
PCDH12 protocadherin 12
PCDHB6 protocadherin beta 6
PCOLCE procollagen C-endopeptidase enhancer
PELO pelota homolog (Drosophila)
PER3 period circadian clock 3
PF4 platelet factor 4
PGK2 phosphoglycerate kinase 2
PHGDH phosphoglycerate dehydrogenase
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKD1L3 polycystic kidney disease 1-like 3
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
PLA2G2F phospholipase A2, group IIF
PLCL2 phospholipase C-like 2
PLEKHA7 pleckstrin homology domain containing, family A member 7
POGK pogo transposable element with KRAB domain
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POTEJ POTE ankyrin domain family, member J
POU6F2 POU class 6 homeobox 2
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRAMEF11 PRAME family member 11
PRDM1 PR domain containing 1, with ZNF domain
PRKCB protein kinase C, beta
PRPF4B pre-mRNA processing factor 4B
PRR12 proline rich 12
PRRC2B proline-rich coiled-coil 2B
PRSS37 protease, serine, 37
RAB19 RAB19, member RAS oncogene family
RBL2 retinoblastoma-like 2
REEP6 receptor accessory protein 6
RELN reelin
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RGN regucalcin
RGPD3 RANBP2-like and GRIP domain containing 3
RIBC1 RIB43A domain with coiled-coils 1
RNF219 ring finger protein 219
RNF39 ring finger protein 39
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RREB1 ras responsive element binding protein 1
RSF1 remodeling and spacing factor 1
SAFB2 scaffold attachment factor B2
SCUBE1 signal peptide, CUB domain, EGF-like 1
SEC16A SEC16 homolog A (S. cerevisiae)
SECISBP2L SECIS binding protein 2-like
SEH1L SEH1-like (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SERAC1 serine active site containing 1
SETBP1 SET binding protein 1
SH2D3C SH2 domain containing 3C
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC16A14 solute carrier family 16, member 14
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC37A3 solute carrier family 37, member 3
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLX4 SLX4 structure-specific endonuclease subunit
SOS2 son of sevenless homolog 2 (Drosophila)
SPEG SPEG complex locus
SPTAN1 spectrin, alpha, non-erythrocytic 1
SSTR4 somatostatin receptor 4
ST18 suppression of tumorigenicity 18, zinc finger
STARD9 StAR-related lipid transfer (START) domain containing 9
STXBP5 syntaxin binding protein 5 (tomosyn)
SV2A synaptic vesicle glycoprotein 2A
SYNE1 spectrin repeat containing, nuclear envelope 1
SYTL2 synaptotagmin-like 2
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAS2R10 taste receptor, type 2, member 10
TAS2R38 taste receptor, type 2, member 38
TAS2R40 taste receptor, type 2, member 40
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TCEAL6 transcription elongation factor A (SII)-like 6
TCF25 transcription factor 25 (basic helix-loop-helix)
TCHHL1 trichohyalin-like 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TENM4 teneurin transmembrane protein 4
TFR2 transferrin receptor 2
THSD7B thrombospondin, type I, domain containing 7B
TMPRSS11E transmembrane protease, serine 11E
TMTC2 transmembrane and tetratricopeptide repeat containing 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNIK TRAF2 and NCK interacting kinase
TP63 tumor protein p63
TPP1 tripeptidyl peptidase I
TPR translocated promoter region, nuclear basket protein
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
TRDN triadin
TRIP12 thyroid hormone receptor interactor 12
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TTF1 transcription termination factor, RNA polymerase I
TTN titin
UBAC2 UBA domain containing 2
UBE3C ubiquitin protein ligase E3C
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC93A unc-93 homolog A (C. elegans)
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIL1 villin 1
VLDLR very low density lipoprotein receptor
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
VWCE von Willebrand factor C and EGF domains
WDR64 WD repeat domain 64
WFS1 Wolfram syndrome 1 (wolframin)
WNT11 wingless-type MMTV integration site family, member 11
WSCD1 WSC domain containing 1
ZBTB14 zinc finger and BTB domain containing 14
ZCCHC11 zinc finger, CCHC domain containing 11
ZKSCAN2 zinc finger with KRAB and SCAN domains 2
ZNF417 zinc finger protein 417
ZNF516 zinc finger protein 516
ZNF570 zinc finger protein 570
ZNF628 zinc finger protein 628
ZNF695 zinc finger protein 695
ZPBP zona pellucida binding protein
ZSCAN5CP zinc finger and SCAN domain containing 5C, pseudogene
ZWINT ZW10 interacting kinetochore protein