HCK Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description HCK proto-oncogene, Src family tyrosine kinase|The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 3055)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_HCK
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Genes

94 co-expressed genes for HCK from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AIF1 allograft inflammatory factor 1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
ARRB2 arrestin, beta 2
BST1 bone marrow stromal cell antigen 1
C5AR1 complement component 5a receptor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCR1 chemokine (C-C motif) receptor 1
CD14 CD14 molecule
CD1D CD1d molecule
CD302 CD302 molecule
CD93 CD93 molecule
CDA cytidine deaminase
CECR1 cat eye syndrome chromosome region, candidate 1
CFP complement factor properdin
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC4A C-type lectin domain family 4, member A
CLEC7A C-type lectin domain family 7, member A
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
COTL1 coactosin-like F-actin binding protein 1
CPVL carboxypeptidase, vitellogenic-like
CTSS cathepsin S
CYBB cytochrome b-245, beta polypeptide
DPEP2 dipeptidase 2
DPYD dihydropyrimidine dehydrogenase
EVI2A ecotropic viral integration site 2A
EVI2B ecotropic viral integration site 2B
FBXL5 F-box and leucine-rich repeat protein 5
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGL2 fibrinogen-like 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FPR1 formyl peptide receptor 1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GABARAP GABA(A) receptor-associated protein
GMIP GEM interacting protein
HCK HCK proto-oncogene, Src family tyrosine kinase
HK3 hexokinase 3 (white cell)
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFNGR1 interferon gamma receptor 1
IGSF6 immunoglobulin superfamily, member 6
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LST1 leukocyte specific transcript 1
LY96 lymphocyte antigen 96
MCL1 myeloid cell leukemia 1
MNDA myeloid cell nuclear differentiation antigen
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYO1F myosin IF
NAGK N-acetylglucosamine kinase
NCF2 neutrophil cytosolic factor 2
NOD2 nucleotide-binding oligomerization domain containing 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PILRA paired immunoglobin-like type 2 receptor alpha
PLBD1 phospholipase B domain containing 1
PPT1 palmitoyl-protein thioesterase 1
PSAP prosaposin
PYCARD PYD and CARD domain containing
RGS2 regulator of G-protein signaling 2
RHOG ras homolog family member G
RNF130 ring finger protein 130
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SDCBP syndecan binding protein (syntenin)
SECTM1 secreted and transmembrane 1
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPI1 Spi-1 proto-oncogene
STX11 syntaxin 11
STXBP2 syntaxin binding protein 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TBXAS1 thromboxane A synthase 1 (platelet)
THEMIS2 thymocyte selection associated family member 2
TLR2 toll-like receptor 2
TLR8 toll-like receptor 8
TMEM127 transmembrane protein 127
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TREM1 triggering receptor expressed on myeloid cells 1
TYMP thymidine phosphorylase
TYROBP TYRO protein tyrosine kinase binding protein
UBE2D1 ubiquitin-conjugating enzyme E2D 1
VNN1 vanin 1
ZNF467 zinc finger protein 467