HCK Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description HCK proto-oncogene, Src family tyrosine kinase|The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 3055)
External Link http://www.ncbi.nlm.nih.gov/gene/3055
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Genes

9 substrates of the kinase HCK from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM15 ADAM metallopeptidase domain 15
BCR breakpoint cluster region
ELMO1 engulfment and cell motility 1
HCK HCK proto-oncogene, Src family tyrosine kinase
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
STAT5B signal transducer and activator of transcription 5B
WAS Wiskott-Aldrich syndrome