| Dataset | GDSC Cell Line Gene Expression Profiles |
| Category | transcriptomics |
| Type | cell line |
| Description | Human colon colorectal carcinoma cell line from a male organism. Human colon carcinoma cell line; established from the primary colon carcinoma of an adult man. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001109) |
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255 genes with high or low expression in HCT-116 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD10 | abhydrolase domain containing 10 | 3.60015 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 2.99028 |
| BBS10 | Bardet-Biedl syndrome 10 | 2.77137 |
| KITLG | KIT ligand | 2.67184 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 2.63827 |
| RNF141 | ring finger protein 141 | 2.59616 |
| CUTC | cutC copper transporter | 2.54386 |
| SSFA2 | sperm specific antigen 2 | 2.52552 |
| WNT16 | wingless-type MMTV integration site family, member 16 | 2.51892 |
| MTAP | methylthioadenosine phosphorylase | 2.49969 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 2.3802 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 2.31097 |
| ARHGAP12 | Rho GTPase activating protein 12 | 2.2951 |
| CLDND1 | claudin domain containing 1 | 2.26156 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 2.25883 |
| ACTR5 | ARP5 actin-related protein 5 homolog (yeast) | 2.25334 |
| ATG12 | autophagy related 12 | 2.24791 |
| HBE1 | hemoglobin, epsilon 1 | 2.23011 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 2.2272 |
| CPOX | coproporphyrinogen oxidase | 2.19834 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa | 2.17598 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 2.14354 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 2.11717 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 2.09574 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 | 2.09486 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 2.09174 |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled | 2.08719 |
| USP46 | ubiquitin specific peptidase 46 | 2.08027 |
| METAP1 | methionyl aminopeptidase 1 | 2.06854 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 2.061 |
| KIF18A | kinesin family member 18A | 2.02408 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | 2.00035 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | 1.96165 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 1.92086 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 1.88806 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 1.88803 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) | 1.88024 |
| STK39 | serine threonine kinase 39 | 1.86472 |
| PDCD11 | programmed cell death 11 | 1.84706 |
| MAGEB2 | melanoma antigen family B2 | 1.8463 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 1.83549 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | 1.83438 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing | 1.82176 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) | 1.81937 |
| EZR | ezrin | 1.81314 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 1.80976 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 1.78689 |
| DCTN6 | dynactin 6 | 1.75349 |
| WNT10B | wingless-type MMTV integration site family, member 10B | 1.7466 |
| TRIB1 | tribbles pseudokinase 1 | 1.72622 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 1.71021 |
| IPO8 | importin 8 | 1.69097 |
| NDC1 | NDC1 transmembrane nucleoporin | 1.67371 |
| PVRL3 | poliovirus receptor-related 3 | 1.67243 |
| SDAD1 | SDA1 domain containing 1 | 1.66902 |
| KLHL12 | kelch-like family member 12 | 1.66771 |
| WDR12 | WD repeat domain 12 | 1.65784 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 1.63301 |
| PTH | parathyroid hormone | 1.62924 |
| PRMT5 | protein arginine methyltransferase 5 | 1.62385 |
| KLRC4 | killer cell lectin-like receptor subfamily C, member 4 | 1.62071 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 | 1.61537 |
| QSER1 | glutamine and serine rich 1 | 1.61479 |
| LPAR3 | lysophosphatidic acid receptor 3 | 1.61479 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 1.61395 |
| KLK7 | kallikrein-related peptidase 7 | 1.61074 |
| PAQR5 | progestin and adipoQ receptor family member V | 1.60193 |
| EIF5A | eukaryotic translation initiation factor 5A | 1.59376 |
| TAS2R8 | taste receptor, type 2, member 8 | 1.59369 |
| ACACA | acetyl-CoA carboxylase alpha | 1.5923 |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa | 1.58484 |
| GLP1R | glucagon-like peptide 1 receptor | 1.58352 |
| TANK | TRAF family member-associated NFKB activator | 1.5833 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 | 1.58227 |
| MOCS3 | molybdenum cofactor synthesis 3 | 1.58194 |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 | 1.57747 |
| PURG | purine-rich element binding protein G | 1.57619 |
| RPAIN | RPA interacting protein | 1.57592 |
| EML2 | echinoderm microtubule associated protein like 2 | 1.57492 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 1.56814 |
| GJA3 | gap junction protein, alpha 3, 46kDa | 1.56412 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase | 1.56363 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 1.56325 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 1.56323 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 1.55242 |
| OLA1 | Obg-like ATPase 1 | 1.54595 |
| TULP2 | tubby like protein 2 | 1.54527 |
| THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) | 1.54453 |
| RCC1 | regulator of chromosome condensation 1 | 1.53506 |
| GJC1 | gap junction protein, gamma 1, 45kDa | 1.53322 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 1.52877 |
| PRDX3 | peroxiredoxin 3 | 1.52449 |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 | 1.5236 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 1.52233 |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta | 1.52054 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 1.51825 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 1.51734 |
| HOXB8 | homeobox B8 | 1.51285 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 1.51222 |
| MDM4 | MDM4, p53 regulator | 1.50823 |
| FHIT | fragile histidine triad | 1.50195 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 | 1.49898 |
| LTA4H | leukotriene A4 hydrolase | 1.4878 |
| TTC19 | tetratricopeptide repeat domain 19 | 1.4877 |
| ZNF286A | zinc finger protein 286A | 1.48265 |
| RPF1 | ribosome production factor 1 homolog (S. cerevisiae) | 1.48153 |
| MYO15A | myosin XVA | 1.47195 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain | 1.46503 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 1.46124 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 1.45888 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 1.44871 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 1.44561 |
| PPARA | peroxisome proliferator-activated receptor alpha | 1.43742 |
| SEC23IP | SEC23 interacting protein | 1.43607 |
| GLUD2 | glutamate dehydrogenase 2 | 1.43039 |
| DLAT | dihydrolipoamide S-acetyltransferase | 1.43017 |
| ANGPTL3 | angiopoietin-like 3 | 1.42945 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 1.42825 |
| NOL11 | nucleolar protein 11 | 1.42676 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | 1.4247 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L | 1.42257 |
| KIAA0040 | KIAA0040 | 1.42025 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATL2 | atlastin GTPase 2 | -3.53717 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | -3.49377 |
| HIST1H3D | histone cluster 1, H3d | -2.58198 |
| ZNF419 | zinc finger protein 419 | -2.55356 |
| METTL9 | methyltransferase like 9 | -2.52204 |
| MSH3 | mutS homolog 3 | -2.52074 |
| RRAGC | Ras-related GTP binding C | -2.49849 |
| SLC25A44 | solute carrier family 25, member 44 | -2.47932 |
| BRD4 | bromodomain containing 4 | -2.41286 |
| SUMO3 | small ubiquitin-like modifier 3 | -2.40378 |
| TRIM31 | tripartite motif containing 31 | -2.39887 |
| IGLJ3 | immunoglobulin lambda joining 3 | -2.39816 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 | -2.3833 |
| KAT6A | K(lysine) acetyltransferase 6A | -2.37962 |
| ZFYVE26 | zinc finger, FYVE domain containing 26 | -2.37955 |
| TAOK1 | TAO kinase 1 | -2.37702 |
| CADM1 | cell adhesion molecule 1 | -2.31699 |
| COMMD9 | COMM domain containing 9 | -2.28286 |
| USP47 | ubiquitin specific peptidase 47 | -2.26832 |
| TNPO1 | transportin 1 | -2.26577 |
| MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase | -2.17497 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | -2.16875 |
| LPA | lipoprotein, Lp(a) | -2.15637 |
| TUG1 | taurine up-regulated 1 (non-protein coding) | -2.15628 |
| SMAP1 | small ArfGAP 1 | -2.1357 |
| NCOR1 | nuclear receptor corepressor 1 | -2.10811 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 | -2.10539 |
| ZNF432 | zinc finger protein 432 | -2.07078 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -2.04462 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 | -2.04249 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -2.02943 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -2.01662 |
| TSSC4 | tumor suppressing subtransferable candidate 4 | -2.01539 |
| KLF1 | Kruppel-like factor 1 (erythroid) | -1.9982 |
| PURA | purine-rich element binding protein A | -1.99732 |
| BMP2 | bone morphogenetic protein 2 | -1.99362 |
| GPATCH3 | G patch domain containing 3 | -1.98949 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | -1.97432 |
| CROT | carnitine O-octanoyltransferase | -1.97147 |
| SNX9 | sorting nexin 9 | -1.94627 |
| FAM179B | family with sequence similarity 179, member B | -1.91313 |
| PKNOX2 | PBX/knotted 1 homeobox 2 | -1.91065 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -1.89546 |
| CCL16 | chemokine (C-C motif) ligand 16 | -1.89181 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | -1.88883 |
| ELMO2 | engulfment and cell motility 2 | -1.88774 |
| EP300 | E1A binding protein p300 | -1.87003 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -1.86534 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | -1.84755 |
| ARR3 | arrestin 3, retinal (X-arrestin) | -1.84629 |
| CLCN7 | chloride channel, voltage-sensitive 7 | -1.84465 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -1.84046 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | -1.80241 |
| KRT17 | keratin 17, type I | -1.79294 |
| RAG2 | recombination activating gene 2 | -1.79227 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -1.78734 |
| SCAND1 | SCAN domain containing 1 | -1.78703 |
| EMC3 | ER membrane protein complex subunit 3 | -1.7704 |
| VEGFC | vascular endothelial growth factor C | -1.76619 |
| ASB8 | ankyrin repeat and SOCS box containing 8 | -1.7628 |
| TP73-AS1 | TP73 antisense RNA 1 | -1.76251 |
| TM6SF1 | transmembrane 6 superfamily member 1 | -1.762 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C | -1.76191 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 | -1.7489 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -1.74661 |
| CBR3 | carbonyl reductase 3 | -1.74558 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein | -1.73565 |
| SCCPDH | saccharopine dehydrogenase (putative) | -1.73398 |
| CD34 | CD34 molecule | -1.73142 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -1.72065 |
| HIST1H4D | histone cluster 1, H4d | -1.71407 |
| LEPROT | leptin receptor overlapping transcript | -1.69746 |
| ZNF282 | zinc finger protein 282 | -1.69745 |
| PLAG1 | pleiomorphic adenoma gene 1 | -1.69227 |
| MRPL28 | mitochondrial ribosomal protein L28 | -1.68021 |
| ZNF140 | zinc finger protein 140 | -1.67912 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | -1.67226 |
| RAB32 | RAB32, member RAS oncogene family | -1.66985 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -1.65927 |
| PENK | proenkephalin | -1.65417 |
| TFE3 | transcription factor binding to IGHM enhancer 3 | -1.65164 |
| NRCAM | neuronal cell adhesion molecule | -1.63618 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -1.62569 |
| LRRN3 | leucine rich repeat neuronal 3 | -1.62095 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) | -1.61475 |
| ZNF446 | zinc finger protein 446 | -1.60837 |
| TXNL4B | thioredoxin-like 4B | -1.60274 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -1.60252 |
| PKNOX1 | PBX/knotted 1 homeobox 1 | -1.60038 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | -1.59606 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -1.59309 |
| APC2 | adenomatosis polyposis coli 2 | -1.59117 |
| FOSL2 | FOS-like antigen 2 | -1.59028 |
| SPHK2 | sphingosine kinase 2 | -1.58211 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -1.56567 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | -1.56281 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | -1.55933 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -1.54941 |
| LRRC19 | leucine rich repeat containing 19 | -1.54101 |
| SLC14A2 | solute carrier family 14 (urea transporter), member 2 | -1.53472 |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | -1.53324 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | -1.53243 |
| CBR1 | carbonyl reductase 1 | -1.53139 |
| DMD | dystrophin | -1.5298 |
| GRIA4 | glutamate receptor, ionotropic, AMPA 4 | -1.52436 |
| IL1A | interleukin 1, alpha | -1.52296 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 | -1.5227 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 | -1.51384 |
| HIST1H2BC | histone cluster 1, H2bc | -1.51293 |
| GPR1 | G protein-coupled receptor 1 | -1.50185 |
| RPAP1 | RNA polymerase II associated protein 1 | -1.50133 |
| CDC42SE2 | CDC42 small effector 2 | -1.49991 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 | -1.49709 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -1.48365 |
| MIP | major intrinsic protein of lens fiber | -1.48122 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -1.47645 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 | -1.46919 |
| NCALD | neurocalcin delta | -1.46906 |
| LRP1 | low density lipoprotein receptor-related protein 1 | -1.4677 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -1.4673 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -1.46369 |
| MED15 | mediator complex subunit 15 | -1.4597 |
| IGHM | immunoglobulin heavy constant mu | -1.45235 |
| ZNF223 | zinc finger protein 223 | -1.44879 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -1.44655 |
| KDM8 | lysine (K)-specific demethylase 8 | -1.44493 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -1.43854 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | -1.43501 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -1.43322 |
| HPSE2 | heparanase 2 (inactive) | -1.42569 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | -1.42564 |
| ALB | albumin | -1.42209 |
| SCNM1 | sodium channel modifier 1 | -1.419 |
