HCV JFH-1_18Hour_20200238_GSE20948 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Viral Infections
Category transcriptomics
Type virus perturbation
Description virus perturbation identified as [virus]_[perturbation]_[publication PMID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE20948
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Genes

600 genes differentially expressed following the HCV JFH-1_18Hour_20200238_GSE20948 virus perturbation from the GEO Signatures of Differentially Expressed Genes for Viral Infections dataset.

increased expression

Symbol Name Standardized Value
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 4.32571
ZNF691 zinc finger protein 691 4.03792
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 3.726
ZNF57 zinc finger protein 57 3.58543
PFKM phosphofructokinase, muscle 3.41951
CD47 CD47 molecule 3.39864
COMMD3 COMM domain containing 3 3.24184
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 3.23737
UBE2L6 ubiquitin-conjugating enzyme E2L 6 3.14522
E2F6 E2F transcription factor 6 3.13312
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.096
POLR1B polymerase (RNA) I polypeptide B, 128kDa 3.08516
MPZL2 myelin protein zero-like 2 3.08196
UBAP2L ubiquitin associated protein 2-like 3.08126
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 3.00612
ESRRA estrogen-related receptor alpha 2.98273
ISG20 interferon stimulated exonuclease gene 20kDa 2.92896
ANTXR2 anthrax toxin receptor 2 2.83043
CTSC cathepsin C 2.82749
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 2.8205
DGAT1 diacylglycerol O-acyltransferase 1 2.82003
CDK4 cyclin-dependent kinase 4 2.81052
ORM1 orosomucoid 1 2.80849
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 2.74403
WDR12 WD repeat domain 12 2.7389
MRPS35 mitochondrial ribosomal protein S35 2.72272
CCDC86 coiled-coil domain containing 86 2.67762
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 2.64139
NQO2 NAD(P)H dehydrogenase, quinone 2 2.63543
PCDH11Y protocadherin 11 Y-linked 2.62641
TMEM45B transmembrane protein 45B 2.60251
EYA4 EYA transcriptional coactivator and phosphatase 4 2.59361
MIRLET7D microRNA let-7d 2.58905
FAM195A family with sequence similarity 195, member A 2.58404
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2.57164
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 2.57131
EIF3D eukaryotic translation initiation factor 3, subunit D 2.57034
INSIG1 insulin induced gene 1 2.54957
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.54761
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 2.54332
SOAT2 sterol O-acyltransferase 2 2.51975
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 2.50811
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.50683
EFNA1 ephrin-A1 2.49284
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 2.47674
NAGLU N-acetylglucosaminidase, alpha 2.42472
ERP29 endoplasmic reticulum protein 29 2.41224
SRPRB signal recognition particle receptor, B subunit 2.38359
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 2.37993
HDDC2 HD domain containing 2 2.3786
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 2.37066
ANG angiogenin, ribonuclease, RNase A family, 5 2.36198
DDIT3 DNA-damage-inducible transcript 3 2.34801
DDIT4 DNA-damage-inducible transcript 4 2.34551
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 2.33981
PRPF4 pre-mRNA processing factor 4 2.33811
TPT1 tumor protein, translationally-controlled 1 2.33748
PGM1 phosphoglucomutase 1 2.32633
RPL29 ribosomal protein L29 2.31811
NFXL1 nuclear transcription factor, X-box binding-like 1 2.31
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 2.29921
EIF6 eukaryotic translation initiation factor 6 2.29669
CECR5 cat eye syndrome chromosome region, candidate 5 2.28552
C19ORF48 chromosome 19 open reading frame 48 2.28035
FAM46A family with sequence similarity 46, member A 2.27217
ETF1 eukaryotic translation termination factor 1 2.26076
MRPL34 mitochondrial ribosomal protein L34 2.24932
IL36G interleukin 36, gamma 2.24163
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.23971
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 2.23896
TCEA2 transcription elongation factor A (SII), 2 2.23425
C19ORF66 chromosome 19 open reading frame 66 2.22546
LOC93622 Morf4 family associated protein 1-like 1 pseudogene 2.2198
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.21676
RPL26L1 ribosomal protein L26-like 1 2.21103
ZCCHC9 zinc finger, CCHC domain containing 9 2.19602
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 2.18564
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.17713
ARPC5L actin related protein 2/3 complex, subunit 5-like 2.17027
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 2.17023
MANBA mannosidase, beta A, lysosomal 2.1696
SLC51B solute carrier family 51, beta subunit 2.16544
VILL villin-like 2.16252
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 2.15798
RNASEH2A ribonuclease H2, subunit A 2.15471
GMDS GDP-mannose 4,6-dehydratase 2.1508
SOX9 SRY (sex determining region Y)-box 9 2.14967
MPC1 mitochondrial pyruvate carrier 1 2.14574
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.14126
CCNH cyclin H 2.14008
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2.13885
TXNL4B thioredoxin-like 4B 2.13291
LUC7L3 LUC7-like 3 (S. cerevisiae) 2.12365
SOD2 superoxide dismutase 2, mitochondrial 2.09977
KCTD6 potassium channel tetramerization domain containing 6 2.09324
LRRTM4 leucine rich repeat transmembrane neuronal 4 2.09104
SEPHS2 selenophosphate synthetase 2 2.08544
GLB1L3 galactosidase, beta 1-like 3 2.07897
FAM129A family with sequence similarity 129, member A 2.07866
UBE2S ubiquitin-conjugating enzyme E2S 2.06154
FARSA phenylalanyl-tRNA synthetase, alpha subunit 2.05473
ETV4 ets variant 4 2.05463
TFAM transcription factor A, mitochondrial 2.05441
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 2.04873
AUNIP aurora kinase A and ninein interacting protein 2.04404
C10ORF2 chromosome 10 open reading frame 2 2.04023
EBNA1BP2 EBNA1 binding protein 2 2.0354
AGR2 anterior gradient 2 2.03163
MARS2 methionyl-tRNA synthetase 2, mitochondrial 2.02627
DUSP12 dual specificity phosphatase 12 2.02468
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 2.01695
R3HCC1L R3H domain and coiled-coil containing 1-like 2.01522
HLA-E major histocompatibility complex, class I, E 2.00106
NOP56 NOP56 ribonucleoprotein 1.99194
CRBN cereblon 1.97934
DIEXF digestive organ expansion factor homolog (zebrafish) 1.97715
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 1.97384
INO80E INO80 complex subunit E 1.96478
DBF4 DBF4 zinc finger 1.95949
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 1.95665
DPH5 diphthamide biosynthesis 5 1.95607
PTTG1 pituitary tumor-transforming 1 1.95126
RNF113A ring finger protein 113A 1.94998
UNG uracil-DNA glycosylase 1.94927
DCXR dicarbonyl/L-xylulose reductase 1.94709
EEF1B2 eukaryotic translation elongation factor 1 beta 2 1.93922
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.93698
TCEAL8 transcription elongation factor A (SII)-like 8 1.9361
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 1.93331
PDRG1 p53 and DNA-damage regulated 1 1.9309
C2 complement component 2 1.93086
STC2 stanniocalcin 2 1.92856
VNN3 vanin 3 1.92235
ASGR2 asialoglycoprotein receptor 2 1.91777
SCGN secretagogin, EF-hand calcium binding protein 1.91743
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 1.91592
SNHG1 small nucleolar RNA host gene 1 1.91211
ZNF232 zinc finger protein 232 1.90786
DANCR differentiation antagonizing non-protein coding RNA 1.90642
CHRM2 cholinergic receptor, muscarinic 2 1.90295
TRIB3 tribbles pseudokinase 3 1.90242
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 1.8979
AARS alanyl-tRNA synthetase 1.89275
TRAPPC2L trafficking protein particle complex 2-like 1.88284
METTL1 methyltransferase like 1 1.88227
AFP alpha-fetoprotein 1.88058
TXNIP thioredoxin interacting protein 1.87718
SPIRE2 spire-type actin nucleation factor 2 1.86808
ARMC10 armadillo repeat containing 10 1.86643
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.86213
CRNDE colorectal neoplasia differentially expressed (non-protein coding) 1.85968
TMEM126A transmembrane protein 126A 1.85419
LOC100505609 uncharacterized LOC100505609 1.8532
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.8476
MRPS2 mitochondrial ribosomal protein S2 1.84282
ANKRD13B ankyrin repeat domain 13B 1.84176
GSTO1 glutathione S-transferase omega 1 1.83622
IPO4 importin 4 1.83604
ODC1 ornithine decarboxylase 1 1.81724
RPL13A ribosomal protein L13a 1.8167
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.81612
HMGA2 high mobility group AT-hook 2 1.81462
ACSL3 acyl-CoA synthetase long-chain family member 3 1.81414
SLC25A38 solute carrier family 25, member 38 1.81262
FLAD1 flavin adenine dinucleotide synthetase 1 1.81126
C1ORF131 chromosome 1 open reading frame 131 1.81084
ZFAND2A zinc finger, AN1-type domain 2A 1.80362
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.80219
NR1H4 nuclear receptor subfamily 1, group H, member 4 1.7969
IFITM3 interferon induced transmembrane protein 3 1.79491
IQCB1 IQ motif containing B1 1.78977
MRPS33 mitochondrial ribosomal protein S33 1.78732
EEF2K eukaryotic elongation factor 2 kinase 1.78218
FAM13B family with sequence similarity 13, member B 1.78001
ZNF747 zinc finger protein 747 1.77802
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 1.77471
CES1 carboxylesterase 1 1.774
LRP10 low density lipoprotein receptor-related protein 10 1.77161
ENOSF1 enolase superfamily member 1 1.77107
C1ORF43 chromosome 1 open reading frame 43 1.77096
MTFP1 mitochondrial fission process 1 1.77023
PCNA proliferating cell nuclear antigen 1.76637
MRPS18B mitochondrial ribosomal protein S18B 1.76343
CHEK2 checkpoint kinase 2 1.7634
TMEM176B transmembrane protein 176B 1.76237
ACOT13 acyl-CoA thioesterase 13 1.75963
IL6R interleukin 6 receptor 1.75847
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 1.7573
AHSG alpha-2-HS-glycoprotein 1.74957
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.74767
RPP25 ribonuclease P/MRP 25kDa subunit 1.74209
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 1.7412
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.74109
MRPL21 mitochondrial ribosomal protein L21 1.73956
TMEM147 transmembrane protein 147 1.73944
FOXK2 forkhead box K2 1.73936
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 1.73694
EXOSC5 exosome component 5 1.7345
LOC646762 uncharacterized LOC646762 1.73322
GDF11 growth differentiation factor 11 1.73309
RBM4B RNA binding motif protein 4B 1.73226
SNHG15 small nucleolar RNA host gene 15 1.72677
AEN apoptosis enhancing nuclease 1.72504
LETMD1 LETM1 domain containing 1 1.72363
RCN1 reticulocalbin 1, EF-hand calcium binding domain 1.71359
PYCR1 pyrroline-5-carboxylate reductase 1 1.71349
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 1.71196
NFYC nuclear transcription factor Y, gamma 1.71137
MRPL48 mitochondrial ribosomal protein L48 1.71042
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.70469
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 1.70428
DESI1 desumoylating isopeptidase 1 1.70338
HNMT histamine N-methyltransferase 1.70337
AMBP alpha-1-microglobulin/bikunin precursor 1.70012
IER2 immediate early response 2 1.69717
PRNP prion protein 1.69571
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.69028
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.68842
GCAT glycine C-acetyltransferase 1.68766
EIF4A3 eukaryotic translation initiation factor 4A3 1.68555
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.68492
TCEAL4 transcription elongation factor A (SII)-like 4 1.67891
DUT deoxyuridine triphosphatase 1.67618
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.67464
RNF126 ring finger protein 126 1.67385
FAM162A family with sequence similarity 162, member A 1.66751
WDR75 WD repeat domain 75 1.6675
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 1.66706
CCL20 chemokine (C-C motif) ligand 20 1.66697
ZNF189 zinc finger protein 189 1.66481
EIF1 eukaryotic translation initiation factor 1 1.66388
TSPAN7 tetraspanin 7 1.66328
CYB5A cytochrome b5 type A (microsomal) 1.65284
SOCS7 suppressor of cytokine signaling 7 1.65273
HINT2 histidine triad nucleotide binding protein 2 1.65264
CAPRIN2 caprin family member 2 1.64657
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae) 1.64598
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 1.64147
RRAGC Ras-related GTP binding C 1.63855
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.63817
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1.63743
C11ORF57 chromosome 11 open reading frame 57 1.63034
RPS14 ribosomal protein S14 1.63029
EPHA5 EPH receptor A5 1.6302
BTG3 BTG family, member 3 1.62979
FEN1 flap structure-specific endonuclease 1 1.62626
ZRANB1 zinc finger, RAN-binding domain containing 1 1.62189
MCU mitochondrial calcium uniporter 1.61241
CTSA cathepsin A 1.6089
GTSF1 gametocyte specific factor 1 1.6081
POPDC3 popeye domain containing 3 1.59788
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 1.59624
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 1.59582
MCPH1 microcephalin 1 1.59357
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 1.59345
TM4SF5 transmembrane 4 L six family member 5 1.59028
ARG2 arginase 2 1.58472
ALG8 ALG8, alpha-1,3-glucosyltransferase 1.56909
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 1.56576
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 1.56295
TRBV21-1 T cell receptor beta variable 21-1 (pseudogene) 1.56288
SIAH1 siah E3 ubiquitin protein ligase 1 1.55993
CPB2 carboxypeptidase B2 (plasma) 1.55945
NARS asparaginyl-tRNA synthetase 1.55872
ZNF256 zinc finger protein 256 1.5579
GCSH glycine cleavage system protein H (aminomethyl carrier) 1.55544
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 1.55504
FDX1 ferredoxin 1 1.55411
CDCA7 cell division cycle associated 7 1.55396
NME4 NME/NM23 nucleoside diphosphate kinase 4 1.55311
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 1.55288
ANKRD16 ankyrin repeat domain 16 1.5512
LY6K lymphocyte antigen 6 complex, locus K 1.54815
GCDH glutaryl-CoA dehydrogenase 1.547
LOC100507316 1.54692
JAGN1 jagunal homolog 1 (Drosophila) 1.5462
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 1.54551
NFIL3 nuclear factor, interleukin 3 regulated 1.5431
TRIM27 tripartite motif containing 27 1.5411
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) 1.5406
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 1.54021
MRPL18 mitochondrial ribosomal protein L18 1.53822
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 1.53628
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 1.53241
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 1.52816
TMEM11 transmembrane protein 11 1.52715
TGFBR3 transforming growth factor, beta receptor III 1.52672
CA2 carbonic anhydrase II 1.52561
U2AF1L4 U2 small nuclear RNA auxiliary factor 1-like 4 1.52512
ZNF416 zinc finger protein 416 1.52511
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 1.52487
C19ORF24 chromosome 19 open reading frame 24 1.52346
C1ORF109 chromosome 1 open reading frame 109 1.52029
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) 1.52018
SEPHS1 selenophosphate synthetase 1 1.52003
UGT8 UDP glycosyltransferase 8 1.51953
GADD45B growth arrest and DNA-damage-inducible, beta 1.5142
AADAC arylacetamide deacetylase 1.51245
PCDH17 protocadherin 17 1.51045
IFRD2 interferon-related developmental regulator 2 1.50967

decreased expression

Symbol Name Standardized Value
LOC642361 uncharacterized LOC642361 -4.22515
MED25 mediator complex subunit 25 -3.32365
TAGLN transgelin -3.3063
CASP6 caspase 6, apoptosis-related cysteine peptidase -3.19186
NOTCH2 notch 2 -3.17963
RNPS1 RNA binding protein S1, serine-rich domain -3.14297
FZD5 frizzled class receptor 5 -3.13404
RAB31 RAB31, member RAS oncogene family -3.07766
WIPI2 WD repeat domain, phosphoinositide interacting 2 -2.90069
GLIPR1 GLI pathogenesis-related 1 -2.89833
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -2.82925
DFNA5 deafness, autosomal dominant 5 -2.82622
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.7993
CTC1 CTS telomere maintenance complex component 1 -2.7373
AP1M2 adaptor-related protein complex 1, mu 2 subunit -2.73183
HSBP1 heat shock factor binding protein 1 -2.72577
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -2.71407
OLFML2A olfactomedin-like 2A -2.68077
IGF1R insulin-like growth factor 1 receptor -2.66504
ANXA3 annexin A3 -2.64351
RRAS related RAS viral (r-ras) oncogene homolog -2.61166
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.60691
PDLIM1 PDZ and LIM domain 1 -2.5965
DDB1 damage-specific DNA binding protein 1, 127kDa -2.54795
EIF5 eukaryotic translation initiation factor 5 -2.51885
CSRP2 cysteine and glycine-rich protein 2 -2.51523
CETN2 centrin, EF-hand protein, 2 -2.5133
ANKRD6 ankyrin repeat domain 6 -2.49991
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 -2.45325
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -2.41051
CTSE cathepsin E -2.40633
ADD1 adducin 1 (alpha) -2.40036
PDLIM7 PDZ and LIM domain 7 (enigma) -2.38014
TUFT1 tuftelin 1 -2.37552
GYPB glycophorin B (MNS blood group) -2.34877
FAM213A family with sequence similarity 213, member A -2.34876
PINK1 PTEN induced putative kinase 1 -2.34399
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -2.30304
TM7SF2 transmembrane 7 superfamily member 2 -2.30148
JOSD1 Josephin domain containing 1 -2.28671
EHD1 EH-domain containing 1 -2.28541
ANXA2P2 annexin A2 pseudogene 2 -2.28375
GYS1 glycogen synthase 1 (muscle) -2.26546
EVI5 ecotropic viral integration site 5 -2.22731
PPL periplakin -2.22394
ARF3 ADP-ribosylation factor 3 -2.22008
ACTG1 actin gamma 1 -2.20219
NRSN1 neurensin 1 -2.19938
TMEM87B transmembrane protein 87B -2.19517
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 -2.19512
NXN nucleoredoxin -2.19136
CFL1 cofilin 1 (non-muscle) -2.16953
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.15635
CSRP1 cysteine and glycine-rich protein 1 -2.15203
MATN2 matrilin 2 -2.14516
TMEM184B transmembrane protein 184B -2.1412
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -2.14067
WFS1 Wolfram syndrome 1 (wolframin) -2.1391
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.1378
FLNB filamin B, beta -2.13293
COX4I1 cytochrome c oxidase subunit IV isoform 1 -2.12799
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -2.12599
KRT17 keratin 17, type I -2.12519
STXBP6 syntaxin binding protein 6 (amisyn) -2.12304
SALL2 spalt-like transcription factor 2 -2.08639
VCP valosin containing protein -2.08463
WDR1 WD repeat domain 1 -2.07731
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -2.06977
PCIF1 PDX1 C-terminal inhibiting factor 1 -2.06955
TUBA1A tubulin, alpha 1a -2.06549
EDN1 endothelin 1 -2.05035
VIL1 villin 1 -2.02785
MYD88 myeloid differentiation primary response 88 -2.02618
WIPF1 WAS/WASL interacting protein family, member 1 -2.02316
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -2.0155
CRISP2 cysteine-rich secretory protein 2 -2.01161
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -2.00167
HSPB1 heat shock 27kDa protein 1 -1.99843
TNNC2 troponin C type 2 (fast) -1.99458
GPX3 glutathione peroxidase 3 -1.99364
ECE1 endothelin converting enzyme 1 -1.98735
LEPROT leptin receptor overlapping transcript -1.97774
TUBB3 tubulin, beta 3 class III -1.97255
STX4 syntaxin 4 -1.97192
DSTN destrin (actin depolymerizing factor) -1.97128
CD58 CD58 molecule -1.95961
NCK2 NCK adaptor protein 2 -1.95522
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -1.955
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -1.95241
NPPB natriuretic peptide B -1.9478
PHTF1 putative homeodomain transcription factor 1 -1.93999
ILK integrin-linked kinase -1.93963
TMCC1 transmembrane and coiled-coil domain family 1 -1.93741
H2AFY2 H2A histone family, member Y2 -1.93642
FAM160B1 family with sequence similarity 160, member B1 -1.93226
TOR1AIP2 torsin A interacting protein 2 -1.91324
RFK riboflavin kinase -1.89525
PDCD10 programmed cell death 10 -1.889
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -1.88843
TMEM50A transmembrane protein 50A -1.88515
PTEN phosphatase and tensin homolog -1.88408
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -1.88269
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -1.8773
CENPI centromere protein I -1.87069
GBP1 guanylate binding protein 1, interferon-inducible -1.86953
FAM89B family with sequence similarity 89, member B -1.86592
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -1.86175
WBP1L WW domain binding protein 1-like -1.85908
CENPB centromere protein B, 80kDa -1.85539
LOXL2 lysyl oxidase-like 2 -1.84822
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -1.84528
NEXN nexilin (F actin binding protein) -1.82562
ODAM odontogenic, ameloblast asssociated -1.80242
SKP1 S-phase kinase-associated protein 1 -1.79145
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -1.78642
FAM219A family with sequence similarity 219, member A -1.78253
MYH9 myosin, heavy chain 9, non-muscle -1.7824
FAM107B family with sequence similarity 107, member B -1.77646
SYNPO synaptopodin -1.7559
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -1.75377
IL32 interleukin 32 -1.74792
IFT122 intraflagellar transport 122 -1.74612
PQLC3 PQ loop repeat containing 3 -1.73984
NRP2 neuropilin 2 -1.73899
MAGED2 melanoma antigen family D2 -1.73317
ATG2A autophagy related 2A -1.72847
MBNL3 muscleblind-like splicing regulator 3 -1.72679
SLIT2 slit homolog 2 (Drosophila) -1.72311
DNASE2B deoxyribonuclease II beta -1.71915
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -1.71569
NSFL1C NSFL1 (p97) cofactor (p47) -1.71454
CYR61 cysteine-rich, angiogenic inducer, 61 -1.69362
TMEM41A transmembrane protein 41A -1.67948
NPHP3 nephronophthisis 3 (adolescent) -1.6761
MPDZ multiple PDZ domain protein -1.6724
TUBB4B tubulin, beta 4B class IVb -1.65689
RTN2 reticulon 2 -1.65398
SYNJ2 synaptojanin 2 -1.6537
AQP10 aquaporin 10 -1.65329
TUBB6 tubulin, beta 6 class V -1.65105
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -1.65099
FBXO3 F-box protein 3 -1.65026
GABARAPL2 GABA(A) receptor-associated protein-like 2 -1.64425
LACTB lactamase, beta -1.64406
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -1.64151
TBC1D13 TBC1 domain family, member 13 -1.63781
MPP1 membrane protein, palmitoylated 1, 55kDa -1.6361
NIPSNAP1 nipsnap homolog 1 (C. elegans) -1.62973
PDXK pyridoxal (pyridoxine, vitamin B6) kinase -1.61678
PRSS35 protease, serine, 35 -1.61529
EMP3 epithelial membrane protein 3 -1.61252
GLCCI1 glucocorticoid induced 1 -1.60718
KIAA0319L KIAA0319-like -1.60344
HSPA2 heat shock 70kDa protein 2 -1.59751
TMEM2 transmembrane protein 2 -1.59576
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -1.59072
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 -1.58924
C11ORF31 chromosome 11 open reading frame 31 -1.58359
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -1.58268
CAPZB capping protein (actin filament) muscle Z-line, beta -1.57635
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -1.57602
HTT huntingtin -1.57225
PNMA1 paraneoplastic Ma antigen 1 -1.56824
HEG1 heart development protein with EGF-like domains 1 -1.56766
LGI2 leucine-rich repeat LGI family, member 2 -1.56537
KIF3B kinesin family member 3B -1.55976
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -1.55265
IP6K2 inositol hexakisphosphate kinase 2 -1.552
CLTB clathrin, light chain B -1.55155
COL5A2 collagen, type V, alpha 2 -1.54856
SKAP2 src kinase associated phosphoprotein 2 -1.54476
LDHA lactate dehydrogenase A -1.53913
ELF5 E74-like factor 5 (ets domain transcription factor) -1.53407
FHL3 four and a half LIM domains 3 -1.53129
FILIP1L filamin A interacting protein 1-like -1.52488
NUBPL nucleotide binding protein-like -1.52402
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase -1.52098
MAPKBP1 mitogen-activated protein kinase binding protein 1 -1.51931
CCDC80 coiled-coil domain containing 80 -1.5137
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.50942
CADM1 cell adhesion molecule 1 -1.50864
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -1.50677
TNIP1 TNFAIP3 interacting protein 1 -1.50613
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -1.50517
FSCN1 fascin actin-bundling protein 1 -1.50475
PRDX1 peroxiredoxin 1 -1.4973
LMCD1 LIM and cysteine-rich domains 1 -1.49166
PRSS23 protease, serine, 23 -1.49089
GAS2L1 growth arrest-specific 2 like 1 -1.48902
ENAH enabled homolog (Drosophila) -1.48818
TGFB1 transforming growth factor, beta 1 -1.48754
CDKN3 cyclin-dependent kinase inhibitor 3 -1.48693
TRAPPC1 trafficking protein particle complex 1 -1.48661
CDON cell adhesion associated, oncogene regulated -1.47928
TIMP2 TIMP metallopeptidase inhibitor 2 -1.47349
PDHB pyruvate dehydrogenase (lipoamide) beta -1.47302
GAL3ST1 galactose-3-O-sulfotransferase 1 -1.46796
CNN1 calponin 1, basic, smooth muscle -1.46529
FBLIM1 filamin binding LIM protein 1 -1.46515
OR5I1 olfactory receptor, family 5, subfamily I, member 1 -1.46412
SLC44A3 solute carrier family 44, member 3 -1.46267
C10ORF35 chromosome 10 open reading frame 35 -1.45913
ORC3 origin recognition complex, subunit 3 -1.45499
STK38 serine/threonine kinase 38 -1.44669
YLPM1 YLP motif containing 1 -1.44416
DGCR8 DGCR8 microprocessor complex subunit -1.44269
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 -1.44091
SNX7 sorting nexin 7 -1.4406
ACTB actin, beta -1.4391
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -1.43805
RPL23A ribosomal protein L23a -1.43782
SORBS2 sorbin and SH3 domain containing 2 -1.43508
MEF2BNB MEF2B neighbor -1.42655
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -1.41928
KLF7 Kruppel-like factor 7 (ubiquitous) -1.4128
ANKRD29 ankyrin repeat domain 29 -1.41116
PIR pirin (iron-binding nuclear protein) -1.40925
GFOD1 glucose-fructose oxidoreductase domain containing 1 -1.40291
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.39169
SLC16A12 solute carrier family 16, member 12 -1.38953
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -1.38637
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -1.38577
KIF20A kinesin family member 20A -1.38136
GPRASP2 G protein-coupled receptor associated sorting protein 2 -1.37657
TFPI2 tissue factor pathway inhibitor 2 -1.37353
GSTM1 glutathione S-transferase mu 1 -1.37312
STK10 serine/threonine kinase 10 -1.37251
TMEM37 transmembrane protein 37 -1.37214
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 -1.36786
ACAA2 acetyl-CoA acyltransferase 2 -1.36674
SELM selenoprotein M -1.36576
MCRS1 microspherule protein 1 -1.36461
MFSD5 major facilitator superfamily domain containing 5 -1.36435
CCDC33 coiled-coil domain containing 33 -1.36414
DKK1 dickkopf WNT signaling pathway inhibitor 1 -1.36367
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -1.36047
RNF17 ring finger protein 17 -1.36029
ACLY ATP citrate lyase -1.3601
CYLD cylindromatosis (turban tumor syndrome) -1.3595
OLFML3 olfactomedin-like 3 -1.35882
UBE4B ubiquitination factor E4B -1.35817
SYNGR2 synaptogyrin 2 -1.35568
FPGT fucose-1-phosphate guanylyltransferase -1.34901
C11ORF71 chromosome 11 open reading frame 71 -1.34802
CLDN6 claudin 6 -1.34663
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -1.3382
GATS GATS, stromal antigen 3 opposite strand -1.33633
CHPF2 chondroitin polymerizing factor 2 -1.33226
ITGA6 integrin, alpha 6 -1.33113
HBEGF heparin-binding EGF-like growth factor -1.32943
HPX hemopexin -1.32689
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -1.32407
LAYN layilin -1.32172
PAM peptidylglycine alpha-amidating monooxygenase -1.32154
C2CD3 C2 calcium-dependent domain containing 3 -1.32024
TTC1 tetratricopeptide repeat domain 1 -1.31951
GLRX glutaredoxin (thioltransferase) -1.31571
GLIPR2 GLI pathogenesis-related 2 -1.3145
TRIM47 tripartite motif containing 47 -1.31291
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -1.31191
ELF4 E74-like factor 4 (ets domain transcription factor) -1.30907
ALAD aminolevulinate dehydratase -1.30384
FAM169A family with sequence similarity 169, member A -1.30316
AARSD1 alanyl-tRNA synthetase domain containing 1 -1.30158
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -1.29332
ZNF174 zinc finger protein 174 -1.28961
FHL2 four and a half LIM domains 2 -1.28754
TAPT1 transmembrane anterior posterior transformation 1 -1.28343
KIFAP3 kinesin-associated protein 3 -1.28325
MORC2-AS1 MORC2 antisense RNA 1 -1.28314
CX3CL1 chemokine (C-X3-C motif) ligand 1 -1.28192
FAM65A family with sequence similarity 65, member A -1.28173
RAB9B RAB9B, member RAS oncogene family -1.28163
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -1.28053
USH1C Usher syndrome 1C (autosomal recessive, severe) -1.27899
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -1.27884
ACOX3 acyl-CoA oxidase 3, pristanoyl -1.27726
DVL2 dishevelled segment polarity protein 2 -1.27649
CORO1C coronin, actin binding protein, 1C -1.27639
MYO5B myosin VB -1.2757
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -1.27245
FBXW12 F-box and WD repeat domain containing 12 -1.27091
COQ9 coenzyme Q9 -1.26712
SSPN sarcospan -1.25923
MTTP microsomal triglyceride transfer protein -1.25879
TCAF1 TRPM8 channel-associated factor 1 -1.25648
HNF1B HNF1 homeobox B -1.25561
HHEX hematopoietically expressed homeobox -1.25019
OXA1L oxidase (cytochrome c) assembly 1-like -1.24689
SMAD7 SMAD family member 7 -1.2462
ABAT 4-aminobutyrate aminotransferase -1.24439
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -1.24327
RFX5 regulatory factor X, 5 (influences HLA class II expression) -1.24223
MELK maternal embryonic leucine zipper kinase -1.24188
TP53I3 tumor protein p53 inducible protein 3 -1.23903
FAM32A family with sequence similarity 32, member A -1.23703
TGFBI transforming growth factor, beta-induced, 68kDa -1.23677
AMT aminomethyltransferase -1.23217
LSR lipolysis stimulated lipoprotein receptor -1.23178
DHCR7 7-dehydrocholesterol reductase -1.23166
Funding