| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | histone deacetylase 1|Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3065) |
| External Link | https://ncbi.nlm.nih.gov/gene/3065 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the HDAC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.01244 |
| WT1 | Wilms tumor 1 | 0.00972395 |
| GNAS | GNAS complex locus | 0.00954622 |
| PRAME | preferentially expressed antigen in melanoma | 0.00925075 |
| PITX3 | paired-like homeodomain 3 | 0.00913555 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00905848 |
| MUC16 | mucin 16, cell surface associated | 0.00896226 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00883274 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.00877316 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.0086822 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.008505 |
| IFI44 | interferon-induced protein 44 | 0.0083046 |
| XIC | X chromosome inactivation center | 0.00825122 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00818847 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00818382 |
| IFI44L | interferon-induced protein 44-like | 0.00814665 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00812588 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00807698 |
| COQ8A | coenzyme Q8A | 0.00805248 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00805134 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00803301 |
| CLIC5 | chloride intracellular channel 5 | 0.0079998 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00782396 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00756538 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00753101 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0075023 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00739095 |
| ADAR | adenosine deaminase, RNA-specific | 0.00734217 |
| ANXA1 | annexin A1 | 0.00733483 |
| CALB1 | calbindin 1, 28kDa | 0.00730907 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00727184 |
| SPRR1B | small proline-rich protein 1B | 0.00696403 |
| PROM1 | prominin 1 | 0.00676166 |
| HTRA1 | HtrA serine peptidase 1 | 0.00672685 |
| PRKCA | protein kinase C, alpha | 0.00672449 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.00671169 |
| KRT14 | keratin 14, type I | 0.00670671 |
| CLDN10 | claudin 10 | 0.00668878 |
| TAPBP | TAP binding protein (tapasin) | 0.00666031 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00661009 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00649851 |
| S100A9 | S100 calcium binding protein A9 | 0.00649495 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 0.00645473 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.0064144 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00639067 |
| ZYX | zyxin | 0.00634997 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00632636 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0063122 |
| S100A7 | S100 calcium binding protein A7 | 0.00629368 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.00626887 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00624348 |
| USP18 | ubiquitin specific peptidase 18 | 0.00620397 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00618121 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00616507 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00614754 |
| KLK10 | kallikrein-related peptidase 10 | 0.00610545 |
| COG7 | component of oligomeric golgi complex 7 | 0.00609966 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00608818 |
| SRGN | serglycin | 0.00604914 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00603953 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00601877 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00600689 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00598456 |
| TOX | thymocyte selection-associated high mobility group box | 0.005976 |
| FOXG1 | forkhead box G1 | 0.00593061 |
| S100A8 | S100 calcium binding protein A8 | 0.00590274 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00583293 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | 0.00582837 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00582236 |
| G6PC | glucose-6-phosphatase, catalytic subunit | 0.00581399 |
| HAL | histidine ammonia-lyase | 0.00580963 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00574079 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00572293 |
| BMP7 | bone morphogenetic protein 7 | 0.00570008 |
| DEFB1 | defensin, beta 1 | 0.00566138 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00566077 |
| PAH | phenylalanine hydroxylase | 0.00565983 |
| PTHLH | parathyroid hormone-like hormone | 0.00563678 |
| KNG1 | kininogen 1 | 0.00563519 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00562347 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00561923 |
| AQP9 | aquaporin 9 | 0.00561826 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00561016 |
| STC2 | stanniocalcin 2 | 0.00560657 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.00559535 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 | 0.00558139 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.00556465 |
| CA12 | carbonic anhydrase XII | 0.00555384 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00552522 |
| SPRR3 | small proline-rich protein 3 | 0.0054906 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 0.00548104 |
| ZNF83 | zinc finger protein 83 | 0.00545481 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00539591 |
| RAI14 | retinoic acid induced 14 | 0.00539519 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00539017 |
| SHFL | shiftless antiviral inhibitor of ribosomal frameshifting | 0.00536413 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.00536027 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00535789 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00533096 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.00533016 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00531594 |
| VNN1 | vanin 1 | 0.00530293 |
| GAP43 | growth associated protein 43 | 0.00530089 |
| SP100 | SP100 nuclear antigen | 0.00529277 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.00528777 |
| MSX1 | msh homeobox 1 | 0.00526303 |
| MMP10 | matrix metallopeptidase 10 | 0.0052322 |
| FJX1 | four jointed box 1 (Drosophila) | 0.00521516 |
| C5AR1 | complement component 5a receptor 1 | 0.00521124 |
| ATF5 | activating transcription factor 5 | 0.00518031 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00517535 |
| DENND1B | DENN/MADD domain containing 1B | 0.00516824 |
| OXTR | oxytocin receptor | 0.00515741 |
| SUSD5 | sushi domain containing 5 | 0.00514765 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00512588 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00512135 |
| RHCG | Rh family, C glycoprotein | 0.00511442 |
| MECOM | MDS1 and EVI1 complex locus | 0.00511021 |
| GSTK1 | glutathione S-transferase kappa 1 | 0.00506886 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00506725 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00506676 |
| MSLN | mesothelin | 0.00503705 |
| GANAB | glucosidase, alpha; neutral AB | 0.0050324 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.00501007 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00500842 |
| FBXO11 | F-box protein 11 | 0.0050016 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00498426 |
| AGRN | agrin | 0.00496185 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00495461 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.00494864 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | 0.00494857 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.00494581 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00494165 |
| AFM | afamin | 0.00493654 |
| TPP1 | tripeptidyl peptidase I | 0.0049348 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00492588 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00491966 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00490905 |
| CD96 | CD96 molecule | 0.00490862 |
| MPDZ | multiple PDZ domain protein | 0.00490292 |
| IL2RG | interleukin 2 receptor, gamma | 0.00490107 |
| RAB13 | RAB13, member RAS oncogene family | 0.004895 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00489395 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.00486562 |
| AHCY | adenosylhomocysteinase | 0.00484607 |
| ATF4 | activating transcription factor 4 | 0.00481286 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00481176 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00479709 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00479007 |
| MMP8 | matrix metallopeptidase 8 | 0.00478412 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0047696 |
| USP25 | ubiquitin specific peptidase 25 | 0.00476105 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00474411 |
| BRD4 | bromodomain containing 4 | 0.00473842 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00473207 |
| ZNF3 | zinc finger protein 3 | 0.0047066 |
| WIF1 | WNT inhibitory factor 1 | 0.0047043 |
| PF4 | platelet factor 4 | 0.00469844 |
| BRD2 | bromodomain containing 2 | 0.00468983 |
| MAP9 | microtubule-associated protein 9 | 0.00468817 |
| NVL | nuclear VCP-like | 0.00467932 |
| FZD2 | frizzled class receptor 2 | 0.00467882 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0046753 |
| HEATR1 | HEAT repeat containing 1 | 0.00466126 |
| DAXX | death-domain associated protein | 0.00466058 |
| FAM169A | family with sequence similarity 169, member A | 0.00465479 |
| IRF7 | interferon regulatory factor 7 | 0.00464933 |
| CTSD | cathepsin D | 0.00464801 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.00463203 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | 0.00462944 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00462381 |
| CARM1 | coactivator-associated arginine methyltransferase 1 | 0.0046196 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.00461201 |
| LEPROT | leptin receptor overlapping transcript | 0.0046116 |
| NRBF2 | nuclear receptor binding factor 2 | 0.00457927 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00456979 |
| SIRT3 | sirtuin 3 | 0.00456661 |
| SYT17 | synaptotagmin XVII | 0.00456482 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00456205 |
| SP110 | SP110 nuclear body protein | 0.00455771 |
| MOCS1 | molybdenum cofactor synthesis 1 | 0.00455754 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.00452142 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.00451943 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.00451807 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00451663 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00450597 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00450309 |
| GPC5 | glypican 5 | 0.00448243 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00448057 |
| TSPAN3 | tetraspanin 3 | 0.00447906 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) | 0.00447231 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00446866 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00445718 |
| LEPR | leptin receptor | 0.00445181 |
| F9 | coagulation factor IX | 0.0044451 |
| ADD3 | adducin 3 (gamma) | 0.00444139 |
| KLK8 | kallikrein-related peptidase 8 | 0.00443708 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.004436 |
| EMX2 | empty spiracles homeobox 2 | 0.00442845 |
| USP6NL | USP6 N-terminal like | 0.00441226 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00440122 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.00439686 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00439565 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00439051 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0043905 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.00438813 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00438257 |
| RUNX3 | runt-related transcription factor 3 | 0.00436898 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 0.00436702 |
| AKR1D1 | aldo-keto reductase family 1, member D1 | 0.00436201 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00435576 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00435335 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00435118 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00433348 |
| NPR3 | natriuretic peptide receptor 3 | 0.00432978 |
| RCAN1 | regulator of calcineurin 1 | 0.00432914 |
| GRN | granulin | 0.00432302 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00431834 |
| SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.00431632 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00430405 |
| BBX | bobby sox homolog (Drosophila) | 0.00429114 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 0.00428842 |
| TUBA1A | tubulin, alpha 1a | 0.00428382 |
| MX1 | MX dynamin-like GTPase 1 | 0.00428344 |
| ESR1 | estrogen receptor 1 | 0.00428266 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00426524 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00425906 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | 0.00425776 |
| NLGN1 | neuroligin 1 | 0.0042525 |
| MRC2 | mannose receptor, C type 2 | 0.00424539 |
| ZNF274 | zinc finger protein 274 | 0.00423839 |
| PTGES | prostaglandin E synthase | 0.00422903 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0042249 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00422273 |
| WLS | wntless Wnt ligand secretion mediator | 0.00422212 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00421537 |
| HOMER1 | homer scaffolding protein 1 | 0.00421394 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00421233 |
| CTSW | cathepsin W | 0.0042115 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00416934 |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter), member 1 | 0.00415848 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.00415799 |
| PRKCQ | protein kinase C, theta | 0.00415461 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00415256 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.0041525 |
| PTCH1 | patched 1 | 0.00415014 |
| CA3 | carbonic anhydrase III | 0.00414611 |
| CLEC2D | C-type lectin domain family 2, member D | 0.00414066 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00413685 |
| FOXC1 | forkhead box C1 | 0.00413662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MGP | matrix Gla protein | -0.0132427 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.013069 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0125735 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0125562 |
| MAP7 | microtubule-associated protein 7 | -0.0122273 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0118024 |
| CPE | carboxypeptidase E | -0.0116891 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0109891 |
| LUM | lumican | -0.00979212 |
| LYZ | lysozyme | -0.00941908 |
| FCGBP | Fc fragment of IgG binding protein | -0.00938696 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00921632 |
| PRDX2 | peroxiredoxin 2 | -0.00893648 |
| S100A4 | S100 calcium binding protein A4 | -0.00890939 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00888194 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00883378 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00876218 |
| RCAN2 | regulator of calcineurin 2 | -0.00873004 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00870725 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00866314 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00856527 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00856163 |
| GPX2 | glutathione peroxidase 2 | -0.00856136 |
| FGF13 | fibroblast growth factor 13 | -0.00843997 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | -0.00842098 |
| PCP4 | Purkinje cell protein 4 | -0.00827525 |
| FGL2 | fibrinogen-like 2 | -0.00823473 |
| CHKB | choline kinase beta | -0.00818037 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.00813506 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00812274 |
| TBX3 | T-box 3 | -0.00802031 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00798971 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00789588 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00782519 |
| ADIRF | adipogenesis regulatory factor | -0.00778462 |
| METTL7A | methyltransferase like 7A | -0.00776773 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00772376 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00768631 |
| DUSP5 | dual specificity phosphatase 5 | -0.0076636 |
| MT1E | metallothionein 1E | -0.00758356 |
| CNN3 | calponin 3, acidic | -0.00756911 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00751579 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00749641 |
| TOX3 | TOX high mobility group box family member 3 | -0.00742411 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00741873 |
| DCN | decorin | -0.00740559 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00738613 |
| PFKL | phosphofructokinase, liver | -0.00733764 |
| RGS5 | regulator of G-protein signaling 5 | -0.00731756 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00727605 |
| DIXDC1 | DIX domain containing 1 | -0.00722549 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00720913 |
| ANXA5 | annexin A5 | -0.00720623 |
| CD93 | CD93 molecule | -0.00719303 |
| LTF | lactotransferrin | -0.00718504 |
| APOD | apolipoprotein D | -0.00717721 |
| GPX3 | glutathione peroxidase 3 | -0.00715736 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00715433 |
| AXL | AXL receptor tyrosine kinase | -0.0070693 |
| SDC2 | syndecan 2 | -0.00690789 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00686138 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00678796 |
| FBLN1 | fibulin 1 | -0.00672206 |
| MDFIC | MyoD family inhibitor domain containing | -0.00669346 |
| STAP2 | signal transducing adaptor family member 2 | -0.0066461 |
| GPX1 | glutathione peroxidase 1 | -0.00654659 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00654114 |
| MGST2 | microsomal glutathione S-transferase 2 | -0.00649707 |
| CLU | clusterin | -0.00646364 |
| AGR2 | anterior gradient 2 | -0.00645662 |
| FOXF1 | forkhead box F1 | -0.00644928 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00643105 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00640569 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00636171 |
| MIR22HG | MIR22 host gene | -0.00634147 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00631897 |
| RBPMS | RNA binding protein with multiple splicing | -0.00630458 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00627658 |
| WTAP | Wilms tumor 1 associated protein | -0.00627207 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00625407 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00624986 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00623832 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00623235 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | -0.00622903 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00622502 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00620582 |
| ATG101 | autophagy related 101 | -0.00619869 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00618386 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00616636 |
| CALD1 | caldesmon 1 | -0.00616004 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00615605 |
| CLCA1 | chloride channel accessory 1 | -0.00612279 |
| MAOA | monoamine oxidase A | -0.00610773 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00609908 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00609154 |
| CTSH | cathepsin H | -0.00608357 |
| PLVAP | plasmalemma vesicle associated protein | -0.00606083 |
| KYNU | kynureninase | -0.00605574 |
| DES | desmin | -0.00602421 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0060214 |
| CADM1 | cell adhesion molecule 1 | -0.00600611 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00598558 |
| BAG2 | BCL2-associated athanogene 2 | -0.00593937 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00593335 |
| SEPTIN10 | septin 10 | -0.00590461 |
| EMP3 | epithelial membrane protein 3 | -0.00588177 |
| HHEX | hematopoietically expressed homeobox | -0.00588157 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00587723 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00587403 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00584338 |
| CNN1 | calponin 1, basic, smooth muscle | -0.0058373 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00580797 |
| EAPP | E2F-associated phosphoprotein | -0.00579561 |
| CCN2 | cellular communication network factor 2 | -0.00578874 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00578519 |
| MSRB2 | methionine sulfoxide reductase B2 | -0.00576977 |
| RAB4A | RAB4A, member RAS oncogene family | -0.00571679 |
| ADI1 | acireductone dioxygenase 1 | -0.0056937 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00568695 |
| PGC | progastricsin (pepsinogen C) | -0.00566793 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00566506 |
| BTG2 | BTG family, member 2 | -0.00566493 |
| ODC1 | ornithine decarboxylase 1 | -0.00563951 |
| RANBP1 | RAN binding protein 1 | -0.00563731 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00563414 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00561938 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00561432 |
| PLN | phospholamban | -0.00561086 |
| BAD | BCL2-associated agonist of cell death | -0.00560327 |
| MOB4 | MOB family member 4, phocein | -0.00558812 |
| KRT8 | keratin 8, type II | -0.00558547 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00557476 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.00555718 |
| WDR7 | WD repeat domain 7 | -0.00554391 |
| ASPH | aspartate beta-hydroxylase | -0.00552365 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00551496 |
| ITGA6 | integrin, alpha 6 | -0.00550204 |
| POSTN | periostin, osteoblast specific factor | -0.00549249 |
| BSG | basigin (Ok blood group) | -0.00549245 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00548924 |
| CD163 | CD163 molecule | -0.00548146 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00547169 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00546986 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00546931 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00545793 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00545454 |
| NINJ2 | ninjurin 2 | -0.00544591 |
| CD14 | CD14 molecule | -0.00544174 |
| TMEM14B | transmembrane protein 14B | -0.00542261 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00537918 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0053666 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00534949 |
| TUBA4A | tubulin, alpha 4a | -0.0053463 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00533632 |
| TMSB15A | thymosin beta 15a | -0.00533606 |
| LPXN | leupaxin | -0.00533569 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | -0.0053208 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00531869 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00531359 |
| GSN | gelsolin | -0.00530479 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | -0.0053007 |
| TXN | thioredoxin | -0.0052983 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00529351 |
| REEP1 | receptor accessory protein 1 | -0.00527393 |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) | -0.00526259 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00525558 |
| TMEM14A | transmembrane protein 14A | -0.00525274 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | -0.00522256 |
| HMGB3 | high mobility group box 3 | -0.00520749 |
| FAM162A | family with sequence similarity 162, member A | -0.00519561 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00518556 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00517293 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0051589 |
| SRP54 | signal recognition particle 54kDa | -0.00512298 |
| H2AX | H2A.X variant histone | -0.00510509 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00510465 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00509812 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | -0.00509601 |
| TPRKB | TP53RK binding protein | -0.00509428 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.00508537 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00508334 |
| AOC3 | amine oxidase, copper containing 3 | -0.0050776 |
| QDPR | quinoid dihydropteridine reductase | -0.00505093 |
| PIGR | polymeric immunoglobulin receptor | -0.00503629 |
| IRF8 | interferon regulatory factor 8 | -0.00503083 |
| TPD52L1 | tumor protein D52-like 1 | -0.0050203 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00501064 |
| CENPX | centromere protein X | -0.00500592 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.00499862 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.00499772 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00498835 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00498747 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00497901 |
| MT1F | metallothionein 1F | -0.00496187 |
| RBM47 | RNA binding motif protein 47 | -0.00496067 |
| MFAP5 | microfibrillar associated protein 5 | -0.00495831 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00494934 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0049453 |
| VWA1 | von Willebrand factor A domain containing 1 | -0.00494475 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00494102 |
| PMP22 | peripheral myelin protein 22 | -0.00493596 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00493178 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A | -0.00491644 |
| CHMP6 | charged multivesicular body protein 6 | -0.00491614 |
| PRKCZ | protein kinase C, zeta | -0.00490687 |
| CFH | complement factor H | -0.00490635 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -0.00490128 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.00489884 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00488898 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00488387 |
| MPZL2 | myelin protein zero-like 2 | -0.00488313 |
| APOC1 | apolipoprotein C-I | -0.00488303 |
| HBB | hemoglobin, beta | -0.00488086 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00487872 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 | -0.00486903 |
| SDF4 | stromal cell derived factor 4 | -0.00485989 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00485712 |
| SQLE | squalene epoxidase | -0.00485265 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00485047 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00484774 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00481566 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.00481251 |
| TAGLN | transgelin | -0.00481094 |
| STMN2 | stathmin 2 | -0.00480794 |
| UBE2N | ubiquitin-conjugating enzyme E2N | -0.0048025 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00480097 |
| RRAGA | Ras-related GTP binding A | -0.00478645 |
| SLIRP | SRA stem-loop interacting RNA binding protein | -0.00477937 |
| CYTH1 | cytohesin 1 | -0.00477701 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.0047619 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00474758 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00474348 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00473726 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | -0.00473358 |
| INSIG1 | insulin induced gene 1 | -0.0047208 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00471638 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0047099 |
| BEX4 | brain expressed, X-linked 4 | -0.00469698 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.00469618 |
| APOA1 | apolipoprotein A-I | -0.00467649 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00466898 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00466898 |
| CD177 | CD177 molecule | -0.00466294 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00465668 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.0046536 |
| FBN1 | fibrillin 1 | -0.00465258 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00465004 |
| NMU | neuromedin U | -0.00464922 |
