HDAC1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description histone deacetylase 1|Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3065)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_HDAC1
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Genes

360 co-expressed genes for HDAC1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABT1 activator of basal transcription 1
ACLY ATP citrate lyase
ACP1 acid phosphatase 1, soluble
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
AFG3L2 AFG3-like AAA ATPase 2
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AIP aryl hydrocarbon receptor interacting protein
AK2 adenylate kinase 2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ANAPC5 anaphase promoting complex subunit 5
ANKRD49 ankyrin repeat domain 49
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANXA6 annexin A6
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARF3 ADP-ribosylation factor 3
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATXN10 ataxin 10
BAG6 BCL2-associated athanogene 6
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTF3 basic transcription factor 3
BUB3 BUB3 mitotic checkpoint protein
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CANX calnexin
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CBFB core-binding factor, beta subunit
CBX3 chromobox homolog 3
CCDC59 coiled-coil domain containing 59
CCNI cyclin I
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC123 cell division cycle 123
CDC37 cell division cycle 37
CDC40 cell division cycle 40
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CHD4 chromodomain helicase DNA binding protein 4
CHERP calcium homeostasis endoplasmic reticulum protein
CHMP2A charged multivesicular body protein 2A
CIAO1 cytosolic iron-sulfur assembly component 1
CLK2 CDC-like kinase 2
CLTA clathrin, light chain A
CNOT7 CCR4-NOT transcription complex, subunit 7
COPE coatomer protein complex, subunit epsilon
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COPS7B COP9 signalosome subunit 7B
COX4I1 cytochrome c oxidase subunit IV isoform 1
COX5B cytochrome c oxidase subunit Vb
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
COX7C cytochrome c oxidase subunit VIIc
CS citrate synthase
CSK c-src tyrosine kinase
CSNK2B casein kinase 2, beta polypeptide
CTBP1 C-terminal binding protein 1
CTDNEP1 CTD nuclear envelope phosphatase 1
CYC1 cytochrome c-1
DAP3 death associated protein 3
DDB2 damage-specific DNA binding protein 2, 48kDa
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DEK DEK proto-oncogene
DGKZ diacylglycerol kinase, zeta
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DIAPH1 diaphanous-related formin 1
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
DRG1 developmentally regulated GTP binding protein 1
DUT deoxyuridine triphosphatase
DYNLL1 dynein, light chain, LC8-type 1
EDC4 enhancer of mRNA decapping 4
EED embryonic ectoderm development
EFCAB14 EF-hand calcium binding domain 14
EID1 EP300 interacting inhibitor of differentiation 1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4H eukaryotic translation initiation factor 4H
ELAC2 elaC ribonuclease Z 2
ERH enhancer of rudimentary homolog (Drosophila)
ERP29 endoplasmic reticulum protein 29
ESD esterase D
EXOSC8 exosome component 8
FAM111A family with sequence similarity 111, member A
FAM120A family with sequence similarity 120A
FAM168B family with sequence similarity 168, member B
FBL fibrillarin
FBXO9 F-box protein 9
FNBP1 formin binding protein 1
FUS FUS RNA binding protein
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GANAB glucosidase, alpha; neutral AB
GDI2 GDP dissociation inhibitor 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPN1 GPN-loop GTPase 1
GPSM3 G-protein signaling modulator 3
GTF3A general transcription factor IIIA
GUSB glucuronidase, beta
H2AFV H2A histone family, member V
H2AFY H2A histone family, member Y
H2AFZ H2A histone family, member Z
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAX1 HCLS1 associated protein X-1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDGF hepatoma-derived growth factor
HMGB2 high mobility group box 2
HMGN1 high mobility group nucleosome binding domain 1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HSPB11 heat shock protein family B (small), member 11
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFI16 interferon, gamma-inducible protein 16
IFRD1 interferon-related developmental regulator 1
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
JTB jumping translocation breakpoint
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KPNB1 karyopherin (importin) beta 1
LMNB2 lamin B2
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MCM3AP minichromosome maintenance complex component 3 associated protein
MDH1 malate dehydrogenase 1, NAD (soluble)
MED12 mediator complex subunit 12
MEN1 multiple endocrine neoplasia I
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MRPL9 mitochondrial ribosomal protein L9
MRPS12 mitochondrial ribosomal protein S12
MTDH metadherin
NACA nascent polypeptide-associated complex alpha subunit
NARS asparaginyl-tRNA synthetase
NASP nuclear autoantigenic sperm protein (histone-binding)
NCL nucleolin
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NOL11 nucleolar protein 11
NONO non-POU domain containing, octamer-binding
NRD1 nardilysin (N-arginine dibasic convertase)
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OSR1 odd-skipped related transciption factor 1
OXA1L oxidase (cytochrome c) assembly 1-like
PABPN1 poly(A) binding protein, nuclear 1
PAPD7 PAP associated domain containing 7
PAPOLA poly(A) polymerase alpha
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PARK7 parkinson protein 7
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDHB pyruvate dehydrogenase (lipoamide) beta
PDIA6 protein disulfide isomerase family A, member 6
PDS5A PDS5 cohesin associated factor A
PFN1 profilin 1
PGK1 phosphoglycerate kinase 1
PHB2 prohibitin 2
PKN1 protein kinase N1
PNRC2 proline-rich nuclear receptor coactivator 2
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PPIE peptidylprolyl isomerase E (cyclophilin E)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRMT1 protein arginine methyltransferase 1
PRPF8 pre-mRNA processing factor 8
PRRC2C proline-rich coiled-coil 2C
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PTBP1 polypyrimidine tract binding protein 1
PTGES3 prostaglandin E synthase 3 (cytosolic)
PUF60 poly-U binding splicing factor 60KDa
R3HDM1 R3H domain containing 1
RAB8A RAB8A, member RAS oncogene family
RAD23A RAD23 homolog A (S. cerevisiae)
RAN RAN, member RAS oncogene family
RBBP4 retinoblastoma binding protein 4
RBBP6 retinoblastoma binding protein 6
RBM10 RNA binding motif protein 10
RBM15 RNA binding motif protein 15
RBM39 RNA binding motif protein 39
RBMX RNA binding motif protein, X-linked
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF44 ring finger protein 44
RNPS1 RNA binding protein S1, serine-rich domain
RPF1 ribosome production factor 1 homolog (S. cerevisiae)
RPL14 ribosomal protein L14
RPL21 ribosomal protein L21
RPL22 ribosomal protein L22
RPL34 ribosomal protein L34
RPN1 ribophorin I
RPS23 ribosomal protein S23
RPS3 ribosomal protein S3
RPS7 ribosomal protein S7
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCAF11 SR-related CTD-associated factor 11
SCAMP3 secretory carrier membrane protein 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SET SET nuclear proto-oncogene
SETD3 SET domain containing 3
SF1 splicing factor 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SF3A2 splicing factor 3a, subunit 2, 66kDa
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SH3BGRL SH3 domain binding glutamate-rich protein like
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMC1A structural maintenance of chromosomes 1A
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SNX3 sorting nexin 3
SREBF2 sterol regulatory element binding transcription factor 2
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRRM1 serine/arginine repetitive matrix 1
SRSF1 serine/arginine-rich splicing factor 1
SRSF10 serine/arginine-rich splicing factor 10
SRSF2 serine/arginine-rich splicing factor 2
SRSF3 serine/arginine-rich splicing factor 3
SRSF4 serine/arginine-rich splicing factor 4
SRSF7 serine/arginine-rich splicing factor 7
SRSF9 serine/arginine-rich splicing factor 9
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2
STARD7 StAR-related lipid transfer (START) domain containing 7
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
SYPL1 synaptophysin-like 1
TADA3 transcriptional adaptor 3
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAPBP TAP binding protein (tapasin)
TARDBP TAR DNA binding protein
TATDN2 TatD DNase domain containing 2
TCEA1 transcription elongation factor A (SII), 1
TCP1 t-complex 1
TEX261 testis expressed 261
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TLK1 tousled-like kinase 1
TMED9 transmembrane emp24 protein transport domain containing 9
TRA2A transformer 2 alpha homolog (Drosophila)
TRA2B transformer 2 beta homolog (Drosophila)
TRAPPC3 trafficking protein particle complex 3
TRIM28 tripartite motif containing 28
TTC1 tetratricopeptide repeat domain 1
TTC31 tetratricopeptide repeat domain 31
TUFM Tu translation elongation factor, mitochondrial
TUG1 taurine up-regulated 1 (non-protein coding)
U2AF1 U2 small nuclear RNA auxiliary factor 1
U2SURP U2 snRNP-associated SURP domain containing
UBA2 ubiquitin-like modifier activating enzyme 2
UBAC1 UBA domain containing 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2N ubiquitin-conjugating enzyme E2N
UBP1 upstream binding protein 1 (LBP-1a)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRC2 ubiquinol-cytochrome c reductase core protein II
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UQCRH ubiquinol-cytochrome c reductase hinge protein
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
UXT ubiquitously-expressed, prefoldin-like chaperone
VBP1 von Hippel-Lindau binding protein 1
VDAC2 voltage-dependent anion channel 2
VDAC3 voltage-dependent anion channel 3
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WDR1 WD repeat domain 1
XPO1 exportin 1
XPO7 exportin 7
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YTHDC1 YTH domain containing 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZBTB1 zinc finger and BTB domain containing 1
ZC3H15 zinc finger CCCH-type containing 15
ZCCHC8 zinc finger, CCHC domain containing 8
ZNF207 zinc finger protein 207