HDAC2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description histone deacetylase 2|This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] (NCBI Entrez Gene Database, 3066)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_HDAC2
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Genes

277 co-expressed genes for HDAC2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACTL6A actin-like 6A
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
AFG3L2 AFG3-like AAA ATPase 2
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ANAPC5 anaphase promoting complex subunit 5
ANKRD17 ankyrin repeat domain 17
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANXA7 annexin A7
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ATG12 autophagy related 12
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMS1 BMS1 ribosome biogenesis factor
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
BZW1 basic leucine zipper and W2 domains 1
C6ORF62 chromosome 6 open reading frame 62
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CDK11A cyclin-dependent kinase 11A
CDK2 cyclin-dependent kinase 2
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHERP calcium homeostasis endoplasmic reticulum protein
CLNS1A chloride channel, nucleotide-sensitive, 1A
CLTC clathrin, heavy chain (Hc)
CNBP CCHC-type zinc finger, nucleic acid binding protein
CNOT3 CCR4-NOT transcription complex, subunit 3
COPS5 COP9 signalosome subunit 5
COQ9 coenzyme Q9
CS citrate synthase
CTDNEP1 CTD nuclear envelope phosphatase 1
CUL1 cullin 1
CYCS cytochrome c, somatic
DARS aspartyl-tRNA synthetase
DCTD dCMP deaminase
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DEK DEK proto-oncogene
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DGKZ diacylglycerol kinase, zeta
DGUOK deoxyguanosine kinase
DKC1 dyskeratosis congenita 1, dyskerin
DLD dihydrolipoamide dehydrogenase
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK3 dedicator of cytokinesis 3
DRG1 developmentally regulated GTP binding protein 1
DUT deoxyuridine triphosphatase
EDC4 enhancer of mRNA decapping 4
EI24 etoposide induced 2.4
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4H eukaryotic translation initiation factor 4H
EPRS glutamyl-prolyl-tRNA synthetase
ESD esterase D
ETF1 eukaryotic translation termination factor 1
F8A1 coagulation factor VIII-associated 1
FAM120A family with sequence similarity 120A
FBXW11 F-box and WD repeat domain containing 11
FH fumarate hydratase
FIBP fibroblast growth factor (acidic) intracellular binding protein
FUS FUS RNA binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GARS glycyl-tRNA synthetase
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPN1 GPN-loop GTPase 1
GTF2A2 general transcription factor IIA, 2, 12kDa
H2AFZ H2A histone family, member Z
HADH hydroxyacyl-CoA dehydrogenase
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAT1 histone acetyltransferase 1
HCCS holocytochrome c synthase
HCFC1 host cell factor C1
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDDC2 HD domain containing 2
HMGN4 high mobility group nucleosomal binding domain 4
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPE1 heat shock 10kDa protein 1
IARS isoleucyl-tRNA synthetase
ICE1 interactor of little elongation complex ELL subunit 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFRD1 interferon-related developmental regulator 1
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IMMT inner membrane protein, mitochondrial
KARS lysyl-tRNA synthetase
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHSRP KH-type splicing regulatory protein
KRIT1 KRIT1, ankyrin repeat containing
LRPPRC leucine-rich pentatricopeptide repeat containing
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAP2K2 mitogen-activated protein kinase kinase 2
MARS methionyl-tRNA synthetase
MCFD2 multiple coagulation factor deficiency 2
MCM2 minichromosome maintenance complex component 2
MCM6 minichromosome maintenance complex component 6
MDH1 malate dehydrogenase 1, NAD (soluble)
METAP1 methionyl aminopeptidase 1
MFAP1 microfibrillar-associated protein 1
MLEC malectin
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MRPL9 mitochondrial ribosomal protein L9
MRPS18B mitochondrial ribosomal protein S18B
MRPS27 mitochondrial ribosomal protein S27
MSH2 mutS homolog 2
MTA1 metastasis associated 1
MTCP1 mature T-cell proliferation 1
MTDH metadherin
MTIF2 mitochondrial translational initiation factor 2
MTX2 metaxin 2
NAE1 NEDD8 activating enzyme E1 subunit 1
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NELFA negative elongation factor complex member A
NNT nicotinamide nucleotide transhydrogenase
NONO non-POU domain containing, octamer-binding
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUDC nudC nuclear distribution protein
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP188 nucleoporin 188kDa
NUP62 nucleoporin 62kDa
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PABPN1 poly(A) binding protein, nuclear 1
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PDHB pyruvate dehydrogenase (lipoamide) beta
PMEL premelanosome protein
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POM121 POM121 transmembrane nucleoporin
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPT1 palmitoyl-protein thioesterase 1
PRDX3 peroxiredoxin 3
PREP prolyl endopeptidase
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF31 pre-mRNA processing factor 31
PRPF8 pre-mRNA processing factor 8
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTDSS1 phosphatidylserine synthase 1
PTGES3 prostaglandin E synthase 3 (cytosolic)
PWP1 PWP1 homolog (S. cerevisiae)
R3HDM1 R3H domain containing 1
RAD21 RAD21 homolog (S. pombe)
RAD23A RAD23 homolog A (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RANBP1 RAN binding protein 1
RBMX RNA binding motif protein, X-linked
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RFC4 replication factor C (activator 1) 4, 37kDa
RNF126 ring finger protein 126
RNF44 ring finger protein 44
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPN1 ribophorin I
RRM1 ribonucleotide reductase M1
RTN4 reticulon 4
RUVBL2 RuvB-like AAA ATPase 2
SAFB scaffold attachment factor B
SART3 squamous cell carcinoma antigen recognized by T cells 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC24C SEC24 family member C
SEC63 SEC63 homolog (S. cerevisiae)
SERBP1 SERPINE1 mRNA binding protein 1
SERP1 stress-associated endoplasmic reticulum protein 1
SET SET nuclear proto-oncogene
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLBP stem-loop binding protein
SMNDC1 survival motor neuron domain containing 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPE small nuclear ribonucleoprotein polypeptide E
SOD1 superoxide dismutase 1, soluble
SON SON DNA binding protein
SRP9 signal recognition particle 9kDa
SRRM1 serine/arginine repetitive matrix 1
SRSF1 serine/arginine-rich splicing factor 1
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSRP1 structure specific recognition protein 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STK24 serine/threonine kinase 24
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUMO1 small ubiquitin-like modifier 1
TARDBP TAR DNA binding protein
TARS threonyl-tRNA synthetase
TCEA1 transcription elongation factor A (SII), 1
TCERG1 transcription elongation regulator 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFDP1 transcription factor Dp-1
TGDS TDP-glucose 4,6-dehydratase
THOC2 THO complex 2
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TM9SF2 transmembrane 9 superfamily member 2
TM9SF4 transmembrane 9 superfamily protein member 4
TNPO3 transportin 3
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TRAPPC3 trafficking protein particle complex 3
TREX2 three prime repair exonuclease 2
TUFM Tu translation elongation factor, mitochondrial
TXLNA taxilin alpha
TXNL4A thioredoxin-like 4A
U2AF1 U2 small nuclear RNA auxiliary factor 1
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UNG uracil-DNA glycosylase
UQCRC2 ubiquinol-cytochrome c reductase core protein II
USP1 ubiquitin specific peptidase 1
VBP1 von Hippel-Lindau binding protein 1
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VDAC3 voltage-dependent anion channel 3
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WHSC1 Wolf-Hirschhorn syndrome candidate 1
XPO1 exportin 1
XPO6 exportin 6
XPO7 exportin 7
XPOT exportin, tRNA
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YARS tyrosyl-tRNA synthetase
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZMYM4 zinc finger, MYM-type 4
ZNF131 zinc finger protein 131
ZPR1 ZPR1 zinc finger
ZWINT ZW10 interacting kinetochore protein
ZZZ3 zinc finger, ZZ-type containing 3