| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | histone deacetylase 4|Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9759) |
| External Link | https://ncbi.nlm.nih.gov/gene/9759 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the HDAC4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT19 | keratin 19, type I | 0.0123511 |
| AK4 | adenylate kinase 4 | 0.00972498 |
| ZNF395 | zinc finger protein 395 | 0.00970865 |
| KYNU | kynureninase | 0.00960458 |
| DEFB1 | defensin, beta 1 | 0.00957383 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00923992 |
| HNMT | histamine N-methyltransferase | 0.00906007 |
| CD9 | CD9 molecule | 0.00903047 |
| DAXX | death-domain associated protein | 0.00902552 |
| RRAGA | Ras-related GTP binding A | 0.00894905 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00879908 |
| CYTH1 | cytohesin 1 | 0.00870377 |
| GPM6B | glycoprotein M6B | 0.00864168 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00844098 |
| STC1 | stanniocalcin 1 | 0.00838157 |
| IFI44L | interferon-induced protein 44-like | 0.00828516 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | 0.0082458 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00820333 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00814466 |
| IL1R1 | interleukin 1 receptor, type I | 0.00802985 |
| CHN1 | chimerin 1 | 0.00794228 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00793302 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00783835 |
| SDC2 | syndecan 2 | 0.00768842 |
| TMSB15A | thymosin beta 15a | 0.00767706 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00763181 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00752175 |
| RNF167 | ring finger protein 167 | 0.00748185 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00746135 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00745255 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00734395 |
| RGCC | regulator of cell cycle | 0.00733617 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00733155 |
| EFHD1 | EF-hand domain family, member D1 | 0.00730867 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00728715 |
| IRF6 | interferon regulatory factor 6 | 0.00724672 |
| GATA3 | GATA binding protein 3 | 0.00721003 |
| SDC4 | syndecan 4 | 0.00719947 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00718747 |
| CHKB | choline kinase beta | 0.00709347 |
| ATF3 | activating transcription factor 3 | 0.00703662 |
| PFKP | phosphofructokinase, platelet | 0.00699785 |
| MAL | mal, T-cell differentiation protein | 0.0069957 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00698516 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00697987 |
| PLPP3 | phospholipid phosphatase 3 | 0.00696497 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00696379 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00695981 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00695115 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00694476 |
| MMP10 | matrix metallopeptidase 10 | 0.00691346 |
| COG5 | component of oligomeric golgi complex 5 | 0.00688887 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00688381 |
| BLNK | B-cell linker | 0.00681681 |
| KRT15 | keratin 15, type I | 0.00681009 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00668591 |
| PRAME | preferentially expressed antigen in melanoma | 0.00668366 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00663808 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00661944 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00652232 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00645752 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00644828 |
| IFI44 | interferon-induced protein 44 | 0.00644124 |
| KRT5 | keratin 5, type II | 0.00642719 |
| PFN2 | profilin 2 | 0.00637075 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00633365 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00631316 |
| KLF6 | Kruppel-like factor 6 | 0.00628528 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00625896 |
| MX1 | MX dynamin-like GTPase 1 | 0.0061756 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00616164 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00614971 |
| METTL7A | methyltransferase like 7A | 0.00612365 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00608153 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.00607403 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00606696 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00605749 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00605267 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00600421 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00598914 |
| MLF1 | myeloid leukemia factor 1 | 0.00596478 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00593193 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00591584 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0058966 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00589639 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00586856 |
| S100A2 | S100 calcium binding protein A2 | 0.00586205 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00579754 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00577869 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00575775 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00575283 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00574759 |
| VEGFA | vascular endothelial growth factor A | 0.00571661 |
| CLDN8 | claudin 8 | 0.00570288 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00568029 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00565567 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00563473 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | 0.00560929 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00560485 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00559575 |
| EVI2A | ecotropic viral integration site 2A | 0.00556545 |
| EPCAM | epithelial cell adhesion molecule | 0.00555136 |
| DSP | desmoplakin | 0.00553578 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00553464 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00551597 |
| CEP68 | centrosomal protein 68kDa | 0.00551249 |
| CYBRD1 | cytochrome b reductase 1 | 0.00549798 |
| NGRN | neugrin, neurite outgrowth associated | 0.00546364 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.00543042 |
| MAGEA3 | melanoma antigen family A3 | 0.00542537 |
| KRT13 | keratin 13, type I | 0.00541357 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00537928 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00537509 |
| SORD | sorbitol dehydrogenase | 0.00536714 |
| USP18 | ubiquitin specific peptidase 18 | 0.00534316 |
| HAT1 | histone acetyltransferase 1 | 0.00533936 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00533864 |
| CHEK2 | checkpoint kinase 2 | 0.00530989 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00529543 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00523402 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00523325 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00522477 |
| PDCD10 | programmed cell death 10 | 0.00522248 |
| CPE | carboxypeptidase E | 0.00520411 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00519989 |
| MT1M | metallothionein 1M | 0.00515488 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00515022 |
| ACKR3 | atypical chemokine receptor 3 | 0.00514436 |
| MYO1D | myosin ID | 0.00513221 |
| MRS2 | MRS2 magnesium transporter | 0.00511674 |
| CLDN7 | claudin 7 | 0.00510966 |
| CLCA4 | chloride channel accessory 4 | 0.00508605 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.00507517 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00507449 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00505494 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00504999 |
| DAZAP2 | DAZ associated protein 2 | 0.00504272 |
| SNX13 | sorting nexin 13 | 0.00502839 |
| SIRT5 | sirtuin 5 | 0.00501956 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00499854 |
| CFH | complement factor H | 0.00498308 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00497265 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00496915 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | 0.00496051 |
| GSTO1 | glutathione S-transferase omega 1 | 0.004957 |
| MT1F | metallothionein 1F | 0.00494903 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00493792 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00492757 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00492494 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0049149 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00484754 |
| FABP1 | fatty acid binding protein 1, liver | 0.00484463 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00483858 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00482999 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00482419 |
| PLSCR1 | phospholipid scramblase 1 | 0.00481496 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00481378 |
| GPC3 | glypican 3 | 0.00481045 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00477223 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00476953 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00475474 |
| CSTA | cystatin A (stefin A) | 0.00475141 |
| IQCG | IQ motif containing G | 0.00474254 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00473441 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00472876 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00472448 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.00470379 |
| CLIC2 | chloride intracellular channel 2 | 0.00468526 |
| CLIC1 | chloride intracellular channel 1 | 0.0046706 |
| TSPAN1 | tetraspanin 1 | 0.0046639 |
| BAG2 | BCL2-associated athanogene 2 | 0.00466312 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00465879 |
| MMP3 | matrix metallopeptidase 3 | 0.00463636 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00462857 |
| NELFE | negative elongation factor complex member E | 0.00461807 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00460054 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00459444 |
| TMEM231 | transmembrane protein 231 | 0.00459385 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.00459042 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00458048 |
| PHGDH | phosphoglycerate dehydrogenase | 0.00457701 |
| TOX3 | TOX high mobility group box family member 3 | 0.00456538 |
| PRKD3 | protein kinase D3 | 0.00456378 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00455804 |
| SIX2 | SIX homeobox 2 | 0.00455686 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00454919 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00453436 |
| GLUD1 | glutamate dehydrogenase 1 | 0.00453399 |
| LEFTY1 | left-right determination factor 1 | 0.00453091 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00452187 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00451962 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.00451138 |
| PEX2 | peroxisomal biogenesis factor 2 | 0.0045067 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00450155 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00449998 |
| TMEM14B | transmembrane protein 14B | 0.00447273 |
| TFRC | transferrin receptor | 0.00447027 |
| MMP1 | matrix metallopeptidase 1 | 0.00445718 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00445021 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00444634 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00444265 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.00443565 |
| DEK | DEK proto-oncogene | 0.00443305 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant | 0.00443014 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00442693 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00442547 |
| NKX3-1 | NK3 homeobox 1 | 0.00442296 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00441728 |
| GPR137B | G protein-coupled receptor 137B | 0.00441679 |
| ABI1 | abl-interactor 1 | 0.00441603 |
| KATNA1 | katanin p60 (ATPase containing) subunit A 1 | 0.00440057 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 0.00439702 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00439701 |
| DAP | death-associated protein | 0.00439135 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0043847 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.004384 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00435025 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00432216 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | 0.00431947 |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.00431246 |
| CD2AP | CD2-associated protein | 0.00431047 |
| TBCC | tubulin folding cofactor C | 0.00429828 |
| ERGIC2 | ERGIC and golgi 2 | 0.00429404 |
| VAMP7 | vesicle-associated membrane protein 7 | 0.00428999 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00428911 |
| CCDC176 | coiled-coil domain containing 176 | 0.00428316 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00427997 |
| CD83 | CD83 molecule | 0.00427618 |
| SPAG16 | sperm associated antigen 16 | 0.00427362 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00427315 |
| TPD52 | tumor protein D52 | 0.00427277 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.00426734 |
| KRT23 | keratin 23, type I | 0.00426678 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00426033 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.00425634 |
| CNN3 | calponin 3, acidic | 0.00425201 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00424939 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00424378 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | 0.00423818 |
| UPK1B | uroplakin 1B | 0.0042278 |
| ZNF3 | zinc finger protein 3 | 0.0042193 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.00421423 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00420677 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00420483 |
| FZD5 | frizzled class receptor 5 | 0.00420007 |
| NDRG1 | N-myc downstream regulated 1 | 0.00419639 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00419635 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00419406 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | 0.00418792 |
| RANBP9 | RAN binding protein 9 | 0.00416939 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0133731 |
| BEX1 | brain expressed, X-linked 1 | -0.00904359 |
| RPS27L | ribosomal protein S27-like | -0.00856764 |
| APOC1 | apolipoprotein C-I | -0.00854984 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00818602 |
| PLK2 | polo-like kinase 2 | -0.00816297 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00780867 |
| NOTCH1 | notch 1 | -0.00774836 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00764158 |
| TESC | tescalcin | -0.00755467 |
| NID2 | nidogen 2 (osteonidogen) | -0.00733759 |
| TYMS | thymidylate synthetase | -0.00716744 |
| TUBB6 | tubulin, beta 6 class V | -0.00709415 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00707071 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00692998 |
| PLXND1 | plexin D1 | -0.00691043 |
| CD320 | CD320 molecule | -0.00683357 |
| METRN | meteorin, glial cell differentiation regulator | -0.0066835 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00657935 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0064649 |
| FHL1 | four and a half LIM domains 1 | -0.00642931 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00635419 |
| S100A8 | S100 calcium binding protein A8 | -0.00632067 |
| CTSE | cathepsin E | -0.00616303 |
| CCNL2 | cyclin L2 | -0.00613803 |
| MAGED1 | melanoma antigen family D1 | -0.00604133 |
| CST1 | cystatin SN | -0.00599914 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00591275 |
| RIN2 | Ras and Rab interactor 2 | -0.00591093 |
| GOLGA8H | golgin A8 family, member H | -0.00587388 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00586853 |
| GOLGA8A | golgin A8 family, member A | -0.0057964 |
| MSLN | mesothelin | -0.00576814 |
| DUSP1 | dual specificity phosphatase 1 | -0.0057643 |
| ZNF721 | zinc finger protein 721 | -0.00573352 |
| ZNF160 | zinc finger protein 160 | -0.00567513 |
| RAPSN | receptor-associated protein of the synapse | -0.00563876 |
| RPL36 | ribosomal protein L36 | -0.00559382 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00558083 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00557957 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00557902 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00555628 |
| NDUFB1 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa | -0.0054723 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00545462 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00544879 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00541519 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -0.00538273 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00536745 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00535425 |
| ELANE | elastase, neutrophil expressed | -0.00531407 |
| NOTCH2NL | notch 2 N-terminal like | -0.00531105 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00530716 |
| WDR6 | WD repeat domain 6 | -0.00528876 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00528003 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00525334 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00523687 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00522031 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00516818 |
| PILRB | paired immunoglobin-like type 2 receptor beta | -0.00515571 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00515002 |
| SIRPA | signal-regulatory protein alpha | -0.00512808 |
| PCLAF | PCNA clamp associated factor | -0.00512527 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00511009 |
| COL5A2 | collagen, type V, alpha 2 | -0.00510339 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00504235 |
| NKTR | natural killer cell triggering receptor | -0.00503386 |
| COQ8A | coenzyme Q8A | -0.00501863 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00494645 |
| CDC25B | cell division cycle 25B | -0.00492426 |
| NOP56 | NOP56 ribonucleoprotein | -0.00490446 |
| NDRG4 | NDRG family member 4 | -0.00486814 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | -0.00486694 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00485636 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -0.00485603 |
| TNS3 | tensin 3 | -0.00485558 |
| LIPG | lipase, endothelial | -0.00484953 |
| GPX3 | glutathione peroxidase 3 | -0.00483169 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00479186 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00478956 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00478109 |
| RGS4 | regulator of G-protein signaling 4 | -0.00474766 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00474316 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | -0.00473172 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0047033 |
| NNMT | nicotinamide N-methyltransferase | -0.00469109 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.00465209 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00464337 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00463721 |
| SFTPC | surfactant protein C | -0.00463125 |
| CTSG | cathepsin G | -0.00461194 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00461149 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00460953 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00460931 |
| PEG10 | paternally expressed 10 | -0.00456394 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00456134 |
| TARP | TCR gamma alternate reading frame protein | -0.00454534 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00454477 |
| STK10 | serine/threonine kinase 10 | -0.00453652 |
| ATP13A1 | ATPase type 13A1 | -0.0045351 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00453368 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00453004 |
| CA3 | carbonic anhydrase III | -0.00452976 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00452055 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | -0.00448024 |
| LXN | latexin | -0.00447391 |
| LST1 | leukocyte specific transcript 1 | -0.00447022 |
| ZNF512B | zinc finger protein 512B | -0.00446717 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00446223 |
| RBM26 | RNA binding motif protein 26 | -0.00446161 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.00446096 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0044488 |
| NOTCH2 | notch 2 | -0.00444826 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.004414 |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 | -0.00439778 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00437018 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00435898 |
| CNPY2 | canopy FGF signaling regulator 2 | -0.00433956 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00433007 |
| SPATA20 | spermatogenesis associated 20 | -0.00432097 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.00431251 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | -0.00431161 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.00430721 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00430528 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -0.0042914 |
| FBXO2 | F-box protein 2 | -0.00428762 |
| TLE4 | transducin-like enhancer of split 4 | -0.00428688 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00428557 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00428154 |
| TG | thyroglobulin | -0.00427883 |
| HIP1 | huntingtin interacting protein 1 | -0.00426221 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | -0.00425951 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0042376 |
| ARGLU1 | arginine and glutamate rich 1 | -0.00423127 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | -0.00422971 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.00421922 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00420263 |
| RXRA | retinoid X receptor, alpha | -0.00418643 |
| EHD3 | EH-domain containing 3 | -0.0041632 |
| PLXNA2 | plexin A2 | -0.00415974 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00413963 |
| MGST2 | microsomal glutathione S-transferase 2 | -0.00413713 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00410059 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00409314 |
| TLR4 | toll-like receptor 4 | -0.00409277 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -0.00408879 |
| ZNF430 | zinc finger protein 430 | -0.00408834 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00408733 |
| ANTKMT | adenine nucleotide translocase lysine methyltransferase | -0.00408452 |
| RPS17 | ribosomal protein S17 | -0.00408264 |
| E2F2 | E2F transcription factor 2 | -0.0040825 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00407643 |
| SFTPA2 | surfactant protein A2 | -0.00407137 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.00406907 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00406828 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00406258 |
| NOP2 | NOP2 nucleolar protein | -0.00404959 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00404157 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00403821 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00402228 |
| RET | ret proto-oncogene | -0.0040216 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00401803 |
| GATAD2A | GATA zinc finger domain containing 2A | -0.00401734 |
| RHOF | ras homolog family member F (in filopodia) | -0.00401314 |
| CTSD | cathepsin D | -0.00400204 |
| MRPL34 | mitochondrial ribosomal protein L34 | -0.00400028 |
| C7 | complement component 7 | -0.00399939 |
| AGR2 | anterior gradient 2 | -0.00399924 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00399558 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | -0.00399495 |
| RGS16 | regulator of G-protein signaling 16 | -0.00397757 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00397316 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00397295 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00394366 |
| CCNA2 | cyclin A2 | -0.0039368 |
| MYO7A | myosin VIIA | -0.00393252 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00392869 |
| TAC1 | tachykinin, precursor 1 | -0.00392502 |
| ITGA7 | integrin, alpha 7 | -0.0039204 |
| SPP1 | secreted phosphoprotein 1 | -0.00391918 |
| PTCH1 | patched 1 | -0.00391759 |
| FADS1 | fatty acid desaturase 1 | -0.0039129 |
| TAGLN | transgelin | -0.00391238 |
| DUSP4 | dual specificity phosphatase 4 | -0.00390342 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | -0.00390091 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00390035 |
| EFNB2 | ephrin-B2 | -0.00389735 |
| HOXC6 | homeobox C6 | -0.00389532 |
| FGG | fibrinogen gamma chain | -0.00388733 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.00387503 |
| TBXAS1 | thromboxane A synthase 1 (platelet) | -0.00387494 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.00386611 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 | -0.00385393 |
| ABHD14A | abhydrolase domain containing 14A | -0.00384904 |
| NPTX2 | neuronal pentraxin II | -0.0038403 |
| CAVIN3 | caveolae associated protein 3 | -0.00383802 |
| PCP4 | Purkinje cell protein 4 | -0.00383314 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00382828 |
| TGFB1 | transforming growth factor, beta 1 | -0.00382757 |
| SLC22A17 | solute carrier family 22, member 17 | -0.00382725 |
| MEN1 | multiple endocrine neoplasia I | -0.00382414 |
| LAMB1 | laminin, beta 1 | -0.00382108 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | -0.0038057 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.00380255 |
| JAG1 | jagged 1 | -0.00380173 |
| PRR11 | proline rich 11 | -0.00379178 |
| MRPL23 | mitochondrial ribosomal protein L23 | -0.00379026 |
| CCDC92 | coiled-coil domain containing 92 | -0.00378443 |
| S100P | S100 calcium binding protein P | -0.00378385 |
| RSRP1 | arginine/serine-rich protein 1 | -0.00377756 |
| RGS5 | regulator of G-protein signaling 5 | -0.00377639 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00377279 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.00376787 |
| CCND1 | cyclin D1 | -0.0037674 |
| VGF | VGF nerve growth factor inducible | -0.00376234 |
| APOE | apolipoprotein E | -0.00376053 |
| MRPL33 | mitochondrial ribosomal protein L33 | -0.00374748 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.00373678 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 | -0.00373649 |
| RCAN1 | regulator of calcineurin 1 | -0.00373609 |
| AZU1 | azurocidin 1 | -0.00372922 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -0.00372232 |
| SIRT3 | sirtuin 3 | -0.00372049 |
| RYR1 | ryanodine receptor 1 (skeletal) | -0.00371339 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | -0.0037058 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.0036936 |
| CAPN15 | calpain 15 | -0.00369024 |
| ETV5 | ets variant 5 | -0.0036846 |
| PLN | phospholamban | -0.00367422 |
| PLCB4 | phospholipase C, beta 4 | -0.00366786 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 | -0.00366277 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00366184 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -0.00365886 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00365714 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -0.00365367 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00365208 |
| PLS3 | plastin 3 | -0.00365079 |
| MYBPC2 | myosin binding protein C, fast type | -0.0036461 |
| SACS | sacsin molecular chaperone | -0.00364245 |
| SLC52A2 | solute carrier family 52 (riboflavin transporter), member 2 | -0.00364208 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.00363777 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | -0.00363517 |
| MIA | melanoma inhibitory activity | -0.0036343 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00362376 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.00361881 |
| CDK11A | cyclin-dependent kinase 11A | -0.00360267 |
| NBEAL2 | neurobeachin-like 2 | -0.00360233 |
| VCAN | versican | -0.00359695 |
| RBPMS | RNA binding protein with multiple splicing | -0.00359567 |
| ATXN7 | ataxin 7 | -0.00359549 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | -0.00359496 |
