HESX1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description HESX homeobox 1|This gene encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Mutations in this gene are associated with septooptic dysplasia, HESX1-related growth hormone deficiency, and combined pituitary hormone deficiency. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8820)
External Link https://ncbi.nlm.nih.gov/gene/8820
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Genes

499 genes differentially expressed following the HESX1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0248901
MAP7 microtubule-associated protein 7 0.0200896
WDR7 WD repeat domain 7 0.0146907
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0126463
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0109585
MBL2 mannose-binding lectin (protein C) 2, soluble 0.0105681
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00982927
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00978199
GAL galanin/GMAP prepropeptide 0.00909365
CYB5A cytochrome b5 type A (microsomal) 0.00904049
HOPX HOP homeobox 0.00878381
PROM1 prominin 1 0.00876369
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00873428
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00872792
NPY1R neuropeptide Y receptor Y1 0.00852798
IRX5 iroquois homeobox 5 0.00824829
THBS1 thrombospondin 1 0.00824545
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.0080106
DCLK1 doublecortin-like kinase 1 0.00799665
CA2 carbonic anhydrase II 0.00782823
PLK1 polo-like kinase 1 0.00780774
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00780635
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00771915
DCK deoxycytidine kinase 0.00759922
SLC44A4 solute carrier family 44, member 4 0.00759666
PLSCR3 phospholipid scramblase 3 0.00744431
CRYM crystallin, mu 0.0070504
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00696563
RAP2A RAP2A, member of RAS oncogene family 0.00674938
AUTS2 autism susceptibility candidate 2 0.00664341
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.00663449
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00649284
PRSS8 protease, serine, 8 0.00647534
VAMP8 vesicle-associated membrane protein 8 0.00645789
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00629998
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00612177
CLU clusterin 0.00612035
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00611819
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00609366
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.00608169
TSPYL5 TSPY-like 5 0.00607804
MELK maternal embryonic leucine zipper kinase 0.00605075
TOX3 TOX high mobility group box family member 3 0.00603244
TNNT1 troponin T type 1 (skeletal, slow) 0.00601232
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00599177
KIAA0125 KIAA0125 0.00598855
SCG5 secretogranin V 0.00597425
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00594811
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.00591467
WT1 Wilms tumor 1 0.0058796
EHF ets homologous factor 0.00585352
HOXC6 homeobox C6 0.00578294
STK26 serine/threonine protein kinase 26 0.00574987
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0057371
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00572627
LDOC1 leucine zipper, down-regulated in cancer 1 0.00567002
MYO6 myosin VI 0.00562599
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.00560138
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00558756
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00557133
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00557108
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00553539
HTRA1 HtrA serine peptidase 1 0.00552649
LSP1 lymphocyte-specific protein 1 0.00549367
CLC Charcot-Leyden crystal galectin 0.0054874
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.00547932
GAS1 growth arrest-specific 1 0.00546439
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00545619
GUCY1B3 guanylate cyclase 1, soluble, beta 3 0.00545604
TXNL4A thioredoxin-like 4A 0.00544091
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.0054234
LIN28A lin-28 homolog A (C. elegans) 0.00542251
SCGB2A1 secretoglobin, family 2A, member 1 0.00539813
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.0053861
AK5 adenylate kinase 5 0.00538304
PLAAT3 phospholipase A and acyltransferase 3 0.00538034
WASL Wiskott-Aldrich syndrome-like 0.00535306
CGRRF1 cell growth regulator with ring finger domain 1 0.00534526
BMP4 bone morphogenetic protein 4 0.00531454
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00529085
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.005258
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00522275
RRAGA Ras-related GTP binding A 0.00522262
ARMCX1 armadillo repeat containing, X-linked 1 0.00520948
PHACTR2 phosphatase and actin regulator 2 0.00520867
LAMP2 lysosomal-associated membrane protein 2 0.00520142
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00519265
TUBA4A tubulin, alpha 4a 0.00519121
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.00516277
CXCL12 chemokine (C-X-C motif) ligand 12 0.00516246
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) 0.00515487
ESR1 estrogen receptor 1 0.00514456
DAPK1 death-associated protein kinase 1 0.00511412
SCGB2A2 secretoglobin, family 2A, member 2 0.00507376
EPHA4 EPH receptor A4 0.00505502
WDTC1 WD and tetratricopeptide repeats 1 0.00504785
RHOD ras homolog family member D 0.00503858
ETNK1 ethanolamine kinase 1 0.00501768
MYH10 myosin, heavy chain 10, non-muscle 0.00501402
OSBPL8 oxysterol binding protein-like 8 0.00499947
CD52 CD52 molecule 0.0049724
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.00496153
IL32 interleukin 32 0.00495566
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.00494124
NPR3 natriuretic peptide receptor 3 0.00493531
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.00492943
FBXO11 F-box protein 11 0.00490739
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00489893
SPON1 spondin 1, extracellular matrix protein 0.00489826
SYT1 synaptotagmin I 0.00488362
CLDN4 claudin 4 0.00488314
PDHX pyruvate dehydrogenase complex, component X 0.00481238
OAZ3 ornithine decarboxylase antizyme 3 0.00481085
PEA15 phosphoprotein enriched in astrocytes 15 0.0048061
NNMT nicotinamide N-methyltransferase 0.00476963
HMGN5 high mobility group nucleosome binding domain 5 0.00476393
KLK5 kallikrein-related peptidase 5 0.00476364
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 0.00473136
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00473106
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00472929
PKP2 plakophilin 2 0.00472145
BEX4 brain expressed, X-linked 4 0.00470553
TXNL1 thioredoxin-like 1 0.00470293
FBP1 fructose-1,6-bisphosphatase 1 0.00469842
KIF1C kinesin family member 1C 0.00468717
SIKE1 suppressor of IKBKE 1 0.00468447
COL4A5 collagen, type IV, alpha 5 0.00467094
NAV3 neuron navigator 3 0.0046648
AHR aryl hydrocarbon receptor 0.00462465
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.00462426
CRYAB crystallin, alpha B 0.00461535
EGR2 early growth response 2 0.00460544
IPO13 importin 13 0.00460408
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 0.00459864
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.00459047
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.00458194
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00457647
FGFR1 fibroblast growth factor receptor 1 0.00457352
SOCS6 suppressor of cytokine signaling 6 0.0045703
LY6E lymphocyte antigen 6 complex, locus E 0.00455816
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00455643
ACAA2 acetyl-CoA acyltransferase 2 0.00452988
TIPRL TOR signaling pathway regulator 0.00452802
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.0045179
NAP1L2 nucleosome assembly protein 1-like 2 0.00451766
OSBPL1A oxysterol binding protein-like 1A 0.00450018
STXBP2 syntaxin binding protein 2 0.00449833
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00448074
GCG glucagon 0.00446787
PXDN peroxidasin 0.0044494
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.00443478
EMX2 empty spiracles homeobox 2 0.00442157
ZCCHC2 zinc finger, CCHC domain containing 2 0.00441989
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00441354
ANPEP alanyl (membrane) aminopeptidase 0.00441215
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.0043984
PNMA8A PNMA family member 8A 0.00439752
KLHDC3 kelch domain containing 3 0.00439318
CD59 CD59 molecule, complement regulatory protein 0.00439002
AKR1C3 aldo-keto reductase family 1, member C3 0.00438866
GSPT2 G1 to S phase transition 2 0.00437016
ADRA2A adrenoceptor alpha 2A 0.00436925
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.0043506
CNIH3 cornichon family AMPA receptor auxiliary protein 3 0.00435043
CRISP3 cysteine-rich secretory protein 3 0.00434444
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 0.00434041
LAPTM4B lysosomal protein transmembrane 4 beta 0.00433144
DGKZ diacylglycerol kinase, zeta 0.00432964
ART3 ADP-ribosyltransferase 3 0.00432883
NPTX2 neuronal pentraxin II 0.00432401
CRABP2 cellular retinoic acid binding protein 2 0.00432357
AAMDC adipogenesis associated, Mth938 domain containing 0.00430427
HBD hemoglobin, delta 0.00429949
NCDN neurochondrin 0.00429228
DOK5 docking protein 5 0.00429077
PAWR PRKC, apoptosis, WT1, regulator 0.00429039
CCDC28B coiled-coil domain containing 28B 0.00427195
KRT10 keratin 10, type I 0.00426919
TOB1 transducer of ERBB2, 1 0.004264
FST follistatin 0.00426244
ETFDH electron-transferring-flavoprotein dehydrogenase 0.00426049
C5ORF30 chromosome 5 open reading frame 30 0.00425421
PLIN3 perilipin 3 0.00425305
PFKM phosphofructokinase, muscle 0.00424886
GET3 guided entry of tail-anchored proteins factor 3, ATPase 0.00423872
PLIN2 perilipin 2 0.00423801
SPART spartin 0.00423299
TPM4 tropomyosin 4 0.00423215
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00421008
RAP1GAP2 RAP1 GTPase activating protein 2 0.00420334
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00418812
ZNF468 zinc finger protein 468 0.00417382
TFF1 trefoil factor 1 0.00416677
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa 0.00416266
MANSC1 MANSC domain containing 1 0.00416209
ARHGAP22 Rho GTPase activating protein 22 0.00415969
PLP1 proteolipid protein 1 0.00415724
KIAA0513 KIAA0513 0.00414842
QPCT glutaminyl-peptide cyclotransferase 0.00414656
FTH1 ferritin, heavy polypeptide 1 0.00414588
FOLR1 folate receptor 1 (adult) 0.00414471
ARMCX2 armadillo repeat containing, X-linked 2 0.00414418
NFE2 nuclear factor, erythroid 2 0.0041417
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00413835
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00413472
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.00412691
MFAP3L microfibrillar-associated protein 3-like 0.00412453
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.0041226
TNNT2 troponin T type 2 (cardiac) 0.00412029
CYB5R2 cytochrome b5 reductase 2 0.00411993
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00411913
RGS13 regulator of G-protein signaling 13 0.00411712
TSPAN12 tetraspanin 12 0.00411537
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.0041135
ATP5MF ATP synthase membrane subunit f 0.00410187
AK4 adenylate kinase 4 0.00409775
STMN2 stathmin 2 0.004095
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 0.00409433
SYN1 synapsin I 0.00408857
TSPAN13 tetraspanin 13 0.00408676
MEOX2 mesenchyme homeobox 2 0.00408156
BST2 bone marrow stromal cell antigen 2 0.00407198
FLRT2 fibronectin leucine rich transmembrane protein 2 0.00407156
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.00406505
PRODH proline dehydrogenase (oxidase) 1 0.00405688
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00405643
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00404087
EN1 engrailed homeobox 1 0.00402101
SNX7 sorting nexin 7 0.00401522
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00400851
CLTB clathrin, light chain B 0.00400377
MAST4 microtubule associated serine/threonine kinase family member 4 0.00400098
GRSF1 G-rich RNA sequence binding factor 1 0.00399648
FJX1 four jointed box 1 (Drosophila) 0.00395728
RSRC1 arginine/serine-rich coiled-coil 1 0.00395587
SUGCT succinyl-CoA:glutarate-CoA transferase 0.00394248
AMDHD2 amidohydrolase domain containing 2 0.00393358
CKS2 CDC28 protein kinase regulatory subunit 2 0.00393221
MB myoglobin 0.00392905
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00391627
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00390833
PKM pyruvate kinase, muscle 0.00390327
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.0039017
SLC46A3 solute carrier family 46, member 3 0.00389888
CDKN3 cyclin-dependent kinase inhibitor 3 0.00389303
GATA6 GATA binding protein 6 0.00389278
YARS1 tyrosyl-tRNA synthetase 1 0.00388769
MLH3 mutL homolog 3 0.00388171
FAM117A family with sequence similarity 117, member A 0.00387928

decreased expression

Symbol Name Standardized Value
COL1A2 collagen, type I, alpha 2 -0.0119628
SPARCL1 SPARC-like 1 (hevin) -0.0118169
CAV1 caveolin 1, caveolae protein, 22kDa -0.0117393
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.0117292
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0114073
COL6A2 collagen, type VI, alpha 2 -0.0112592
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0112
CCL4 chemokine (C-C motif) ligand 4 -0.0108728
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0107347
COL6A1 collagen, type VI, alpha 1 -0.0104727
COL15A1 collagen, type XV, alpha 1 -0.00952484
HSPB1 heat shock 27kDa protein 1 -0.00938
IGFBP5 insulin-like growth factor binding protein 5 -0.0093466
CADM1 cell adhesion molecule 1 -0.00929025
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00891825
TSPAN7 tetraspanin 7 -0.00877421
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00865014
MSX1 msh homeobox 1 -0.00858517
POSTN periostin, osteoblast specific factor -0.00855479
MMP12 matrix metallopeptidase 12 -0.00854098
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00848185
GRK5 G protein-coupled receptor kinase 5 -0.00833043
CD93 CD93 molecule -0.00829756
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00806984
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00806464
COL3A1 collagen, type III, alpha 1 -0.00806201
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00796205
FHL1 four and a half LIM domains 1 -0.00789164
CCL20 chemokine (C-C motif) ligand 20 -0.00786393
CES1 carboxylesterase 1 -0.00783075
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00779603
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00777516
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00775262
RNASET2 ribonuclease T2 -0.0076777
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00767576
CD163 CD163 molecule -0.00764412
LPAR6 lysophosphatidic acid receptor 6 -0.00730481
PLAU plasminogen activator, urokinase -0.00723194
RGCC regulator of cell cycle -0.00723077
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00717308
ALOX5 arachidonate 5-lipoxygenase -0.0071299
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00709395
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00707303
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0070421
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00703637
KYNU kynureninase -0.00698405
COL1A1 collagen, type I, alpha 1 -0.00696518
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00693766
FBLN1 fibulin 1 -0.00691709
MAGEA3 melanoma antigen family A3 -0.00688341
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00686852
ITGA6 integrin, alpha 6 -0.00686725
CFD complement factor D (adipsin) -0.00680053
F13A1 coagulation factor XIII, A1 polypeptide -0.006733
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00671376
CDCA4 cell division cycle associated 4 -0.00670559
PLTP phospholipid transfer protein -0.00667781
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00666251
A2M alpha-2-macroglobulin -0.00665633
G0S2 G0/G1 switch 2 -0.00660193
NINJ1 ninjurin 1 -0.00658244
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00656511
AKAP8 A kinase (PRKA) anchor protein 8 -0.00656259
C1S complement component 1, s subcomponent -0.00652726
IL1B interleukin 1, beta -0.00652447
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -0.00649015
PSAP prosaposin -0.00648943
PCP4 Purkinje cell protein 4 -0.00648481
CTSB cathepsin B -0.00641135
MXRA5 matrix-remodelling associated 5 -0.00638586
SCN3A sodium channel, voltage gated, type III alpha subunit -0.0063799
GSDMB gasdermin B -0.00634762
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.00633561
GLUL glutamate-ammonia ligase -0.00630803
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00629494
MET MET proto-oncogene, receptor tyrosine kinase -0.00623858
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00622364
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00620502
AKAP12 A kinase (PRKA) anchor protein 12 -0.00615478
STC1 stanniocalcin 1 -0.00615176
C1QB complement component 1, q subcomponent, B chain -0.00615109
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 -0.0061268
ZEB1 zinc finger E-box binding homeobox 1 -0.00607696
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.0060548
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00599152
TBX3 T-box 3 -0.00598819
AIM2 absent in melanoma 2 -0.0059804
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.00591717
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00590455
SORD sorbitol dehydrogenase -0.00590448
GOLGA8A golgin A8 family, member A -0.00589801
PCDH9 protocadherin 9 -0.00589063
INSR insulin receptor -0.00581693
PRNP prion protein -0.00581263
TGFBI transforming growth factor, beta-induced, 68kDa -0.00580427
FERMT1 fermitin family member 1 -0.00576853
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00576644
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00575078
IFI6 interferon, alpha-inducible protein 6 -0.00574646
COCH cochlin -0.00574128
GBP2 guanylate binding protein 2, interferon-inducible -0.00573479
RALB v-ral simian leukemia viral oncogene homolog B -0.00563621
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.0056106
ASPH aspartate beta-hydroxylase -0.00558436
PNISR PNN-interacting serine/arginine-rich protein -0.00557013
NID1 nidogen 1 -0.00555366
XCL1 chemokine (C motif) ligand 1 -0.00554662
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -0.00553279
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.00552494
CD99 CD99 molecule -0.00550253
METRN meteorin, glial cell differentiation regulator -0.0054991
SOBP sine oculis binding protein homolog (Drosophila) -0.00549757
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.00549464
CCN2 cellular communication network factor 2 -0.00548976
ZBED2 zinc finger, BED-type containing 2 -0.00548879
SQLE squalene epoxidase -0.00546541
KDM5D lysine (K)-specific demethylase 5D -0.00546383
PRKCA protein kinase C, alpha -0.00546199
PDE4B phosphodiesterase 4B, cAMP-specific -0.00544017
EFHC1 EF-hand domain (C-terminal) containing 1 -0.00541744
MAOA monoamine oxidase A -0.00541099
TMEM230 transmembrane protein 230 -0.00540097
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.0053933
TCTA T-cell leukemia translocation altered -0.00535327
EPS8 epidermal growth factor receptor pathway substrate 8 -0.0053359
PLVAP plasmalemma vesicle associated protein -0.00533442
COL6A3 collagen, type VI, alpha 3 -0.00532641
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.00530386
IVNS1ABP influenza virus NS1A binding protein -0.00523889
CRYBG1 crystallin beta-gamma domain containing 1 -0.00521979
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0051992
PSAT1 phosphoserine aminotransferase 1 -0.00518923
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00514906
DST dystonin -0.00513865
TCF12 transcription factor 12 -0.00512604
FZD6 frizzled class receptor 6 -0.00512578
CRELD2 cysteine-rich with EGF-like domains 2 -0.00512427
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00511574
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00511237
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00510675
C1QA complement component 1, q subcomponent, A chain -0.00508766
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.00508689
ATAD2 ATPase family, AAA domain containing 2 -0.00506011
CLEC2B C-type lectin domain family 2, member B -0.00505108
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00504237
KLF7 Kruppel-like factor 7 (ubiquitous) -0.00503317
EMP1 epithelial membrane protein 1 -0.00503139
SSX1 synovial sarcoma, X breakpoint 1 -0.0050106
S100A10 S100 calcium binding protein A10 -0.00501005
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00500856
AQP1 aquaporin 1 (Colton blood group) -0.00500794
DLG5 discs, large homolog 5 (Drosophila) -0.00500559
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00500532
PNN pinin, desmosome associated protein -0.00500234
KRT15 keratin 15, type I -0.00500211
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00500156
JAG1 jagged 1 -0.00499854
SUN1 Sad1 and UNC84 domain containing 1 -0.00499755
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00499521
GPX2 glutathione peroxidase 2 -0.00499249
SYNM synemin, intermediate filament protein -0.00496763
CAV2 caveolin 2 -0.0049654
CDC42SE1 CDC42 small effector 1 -0.00496215
CYTH1 cytohesin 1 -0.00494148
LRP4 low density lipoprotein receptor-related protein 4 -0.00492538
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.0049201
IL27RA interleukin 27 receptor, alpha -0.00491587
LAMA4 laminin, alpha 4 -0.00491166
CHN2 chimerin 2 -0.00490925
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00490374
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00489104
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00488584
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.00488211
USP3 ubiquitin specific peptidase 3 -0.00486937
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.0048678
GPC3 glypican 3 -0.00486567
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -0.00485545
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00484022
RDX radixin -0.00483796
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00483228
ACD adrenocortical dysplasia homolog (mouse) -0.00483205
RGS1 regulator of G-protein signaling 1 -0.00482932
PBX3 pre-B-cell leukemia homeobox 3 -0.00482528
ESD esterase D -0.00482471
CANX calnexin -0.00482061
SLC35G2 solute carrier family 35, member G2 -0.00480936
ORM1 orosomucoid 1 -0.00480034
VEGFA vascular endothelial growth factor A -0.00479482
PALM paralemmin -0.00479458
PTCH1 patched 1 -0.00478718
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.00478341
SNX13 sorting nexin 13 -0.00477207
CD14 CD14 molecule -0.0047542
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00474147
S100A7 S100 calcium binding protein A7 -0.00473658
MMP7 matrix metallopeptidase 7 -0.00473292
GPM6A glycoprotein M6A -0.00472682
KRT5 keratin 5, type II -0.00472116
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.0047203
TGM2 transglutaminase 2 -0.00468176
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 -0.00466498
COL5A2 collagen, type V, alpha 2 -0.00466465
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00466201
CPM carboxypeptidase M -0.00466132
KRT13 keratin 13, type I -0.0046564
TBL1X transducin (beta)-like 1X-linked -0.00464969
MX1 MX dynamin-like GTPase 1 -0.00463377
TP63 tumor protein p63 -0.0046323
LAMB1 laminin, beta 1 -0.00463151
CHD7 chromodomain helicase DNA binding protein 7 -0.00463088
SORBS1 sorbin and SH3 domain containing 1 -0.00462737
CHRDL1 chordin-like 1 -0.00462529
IFI16 interferon, gamma-inducible protein 16 -0.00461977
DLX2 distal-less homeobox 2 -0.00461536
RANBP2 RAN binding protein 2 -0.0046145
MGP matrix Gla protein -0.00460804
MXRA7 matrix-remodelling associated 7 -0.00458084
VSIG4 V-set and immunoglobulin domain containing 4 -0.00458033
IFI27 interferon, alpha-inducible protein 27 -0.0045772
AOC3 amine oxidase, copper containing 3 -0.00455579
CD83 CD83 molecule -0.00454647
FSD1 fibronectin type III and SPRY domain containing 1 -0.00454197
KRT14 keratin 14, type I -0.00453632
IFI44 interferon-induced protein 44 -0.00452883
HLA-B major histocompatibility complex, class I, B -0.00452881
FGF9 fibroblast growth factor 9 -0.00452284
SH3BP4 SH3-domain binding protein 4 -0.00452219
SRSF1 serine/arginine-rich splicing factor 1 -0.00450823
PRAME preferentially expressed antigen in melanoma -0.00449638
HCRT hypocretin (orexin) neuropeptide precursor -0.00449607
ZFC3H1 zinc finger, C3H1-type containing -0.0044931
NT5E 5'-nucleotidase, ecto (CD73) -0.00448333
BCHE butyrylcholinesterase -0.00447491
RBM39 RNA binding motif protein 39 -0.00447275
KIAA0226L KIAA0226-like -0.0044687
TMX4 thioredoxin-related transmembrane protein 4 -0.00446836
TMEM176B transmembrane protein 176B -0.00446456
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00445696
ZNF337 zinc finger protein 337 -0.00445387
CSTA cystatin A (stefin A) -0.00444656
CNN3 calponin 3, acidic -0.00443952
TYROBP TYRO protein tyrosine kinase binding protein -0.0044393
PCOLCE procollagen C-endopeptidase enhancer -0.00442844
JPT2 Jupiter microtubule associated homolog 2 -0.00442591
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00442564
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00442123
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00442103
LAMC2 laminin, gamma 2 -0.0044156
CTSZ cathepsin Z -0.00441546
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00440359