HEY1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description hes-related family bHLH transcription factor with YRPW motif 1|This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23462)
External Link https://ncbi.nlm.nih.gov/gene/23462
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Genes

499 genes differentially expressed following the HEY1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MDK midkine (neurite growth-promoting factor 2) 0.0151724
LCN2 lipocalin 2 0.0130647
S100P S100 calcium binding protein P 0.0126358
CCL20 chemokine (C-C motif) ligand 20 0.0124835
MMP7 matrix metallopeptidase 7 0.0116495
PLK2 polo-like kinase 2 0.0105278
COPS7A COP9 signalosome subunit 7A 0.0102565
GPR137B G protein-coupled receptor 137B 0.0101738
DIPK1A divergent protein kinase domain 1A 0.0100549
FXYD3 FXYD domain containing ion transport regulator 3 0.0100234
SLPI secretory leukocyte peptidase inhibitor 0.00977303
NUPR1 nuclear protein, transcriptional regulator, 1 0.00973151
PLBD1 phospholipase B domain containing 1 0.00959339
PRAME preferentially expressed antigen in melanoma 0.00946881
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00942141
PDZD2 PDZ domain containing 2 0.00939675
MLF1 myeloid leukemia factor 1 0.0093169
SRPX sushi-repeat containing protein, X-linked 0.00923688
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00922609
AKAP12 A kinase (PRKA) anchor protein 12 0.00886951
SPON2 spondin 2, extracellular matrix protein 0.00871972
TSPAN4 tetraspanin 4 0.00865311
HSPA2 heat shock 70kDa protein 2 0.00864984
NIBAN1 niban apoptosis regulator 1 0.00861166
MAGEA3 melanoma antigen family A3 0.00858381
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00850305
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00848065
MLF2 myeloid leukemia factor 2 0.00842189
NXN nucleoredoxin 0.0083654
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00830547
APOD apolipoprotein D 0.00820997
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00817807
GRB7 growth factor receptor-bound protein 7 0.00808325
CTSK cathepsin K 0.0079943
OSR2 odd-skipped related transciption factor 2 0.00796271
C1S complement component 1, s subcomponent 0.00795133
HSPA1A heat shock 70kDa protein 1A 0.00786062
ZNF91 zinc finger protein 91 0.00784283
ZFP36L1 ZFP36 ring finger protein-like 1 0.00783193
PENK proenkephalin 0.0076386
SPARCL1 SPARC-like 1 (hevin) 0.00762835
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00759037
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00757326
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00754493
TSPO translocator protein (18kDa) 0.00753904
PTN pleiotrophin 0.0074278
CCL5 chemokine (C-C motif) ligand 5 0.0074142
CALML5 calmodulin-like 5 0.00739557
KRT19 keratin 19, type I 0.00737507
IER5 immediate early response 5 0.00736531
STAT5B signal transducer and activator of transcription 5B 0.00724921
CHRDL1 chordin-like 1 0.00723869
WASHC4 WASH complex subunit 4 0.00721885
SNAI2 snail family zinc finger 2 0.00711018
PIR pirin (iron-binding nuclear protein) 0.00710606
ATOX1 antioxidant 1 copper chaperone 0.00708218
C3 complement component 3 0.00707449
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00698943
STK10 serine/threonine kinase 10 0.00698609
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.0069703
EGFL6 EGF-like-domain, multiple 6 0.00696647
ZIC1 Zic family member 1 0.00694359
IFITM3 interferon induced transmembrane protein 3 0.00694073
TMEM134 transmembrane protein 134 0.0069376
IL1B interleukin 1, beta 0.0069124
AMDHD2 amidohydrolase domain containing 2 0.00689508
HTRA1 HtrA serine peptidase 1 0.00685774
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0068363
RUNX3 runt-related transcription factor 3 0.00680376
GPNMB glycoprotein (transmembrane) nmb 0.00676769
MGLL monoglyceride lipase 0.0067068
IFI27 interferon, alpha-inducible protein 27 0.00670432
ANXA4 annexin A4 0.0066939
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00668085
KRT5 keratin 5, type II 0.00665636
SNAP25 synaptosomal-associated protein, 25kDa 0.00665463
CXCL8 chemokine (C-X-C motif) ligand 8 0.0066438
AQP9 aquaporin 9 0.00662587
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00660797
NSG1 neuron specific gene family member 1 0.0066073
CD59 CD59 molecule, complement regulatory protein 0.00660127
C1R complement component 1, r subcomponent 0.00657886
C9ORF16 chromosome 9 open reading frame 16 0.00656851
TRIB2 tribbles pseudokinase 2 0.0065367
FTH1 ferritin, heavy polypeptide 1 0.00651551
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.0065125
MFAP5 microfibrillar associated protein 5 0.00646975
RAB9A RAB9A, member RAS oncogene family 0.00646404
CSRP2 cysteine and glycine-rich protein 2 0.0064509
CCL4 chemokine (C-C motif) ligand 4 0.00643068
MT1X metallothionein 1X 0.00641164
CCND2 cyclin D2 0.00640437
AHR aryl hydrocarbon receptor 0.00637661
TPI1 triosephosphate isomerase 1 0.006375
BCHE butyrylcholinesterase 0.00636031
FST follistatin 0.00635972
INAVA innate immunity activator 0.00634478
GSDME gasdermin E 0.00634401
PTGES prostaglandin E synthase 0.00634359
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00632225
FERMT2 fermitin family member 2 0.00627267
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.0062564
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.0062296
IFI44L interferon-induced protein 44-like 0.00618806
COMT catechol-O-methyltransferase 0.00617314
KLK5 kallikrein-related peptidase 5 0.00614663
ZMAT3 zinc finger, matrin-type 3 0.00613798
EMX2 empty spiracles homeobox 2 0.00607007
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00606934
GSDMB gasdermin B 0.00606235
SCGB2A2 secretoglobin, family 2A, member 2 0.00604244
CTSD cathepsin D 0.00600425
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00600222
PLSCR3 phospholipid scramblase 3 0.00599641
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00598685
MX2 MX dynamin-like GTPase 2 0.00598141
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0059678
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00596314
HOMER1 homer scaffolding protein 1 0.00591081
PHTF2 putative homeodomain transcription factor 2 0.00590745
SYNM synemin, intermediate filament protein 0.0058625
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00585958
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.00585929
MLPH melanophilin 0.00585461
IFI44 interferon-induced protein 44 0.00584614
PIP prolactin-induced protein 0.00584153
PLTP phospholipid transfer protein 0.00580732
S100A9 S100 calcium binding protein A9 0.00578324
QPRT quinolinate phosphoribosyltransferase 0.00576886
EMP3 epithelial membrane protein 3 0.00573709
RGS2 regulator of G-protein signaling 2 0.00572949
LPAR6 lysophosphatidic acid receptor 6 0.00570958
KRT14 keratin 14, type I 0.00570615
PPIC peptidylprolyl isomerase C (cyclophilin C) 0.00570494
CRYAB crystallin, alpha B 0.005688
GBAP1 glucosidase, beta, acid pseudogene 1 0.00565622
MMP19 matrix metallopeptidase 19 0.0056391
RORA RAR-related orphan receptor A 0.0056282
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00561129
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00558942
MAGEA12 melanoma antigen family A12 0.00557866
NUAK1 NUAK family, SNF1-like kinase, 1 0.00556338
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00555898
BCL2A1 BCL2-related protein A1 0.0055447
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00552669
HOPX HOP homeobox 0.0055129
HMGA1 high mobility group AT-hook 1 0.00551285
MXRA7 matrix-remodelling associated 7 0.00548937
ASS1 argininosuccinate synthase 1 0.00547319
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 0.00546813
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00546809
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00546517
IL1RN interleukin 1 receptor antagonist 0.00546282
TARP TCR gamma alternate reading frame protein 0.00543555
HPSE heparanase 0.00540841
FJX1 four jointed box 1 (Drosophila) 0.00538816
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00538397
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00537797
ERGIC2 ERGIC and golgi 2 0.00537567
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00536089
KRT7 keratin 7, type II 0.00533857
LAMA2 laminin, alpha 2 0.00533067
PNMA1 paraneoplastic Ma antigen 1 0.00532733
USP18 ubiquitin specific peptidase 18 0.00531998
PEG3 paternally expressed 3 0.00531747
CD7 CD7 molecule 0.0053157
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00530473
MMP11 matrix metallopeptidase 11 0.00530202
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 0.00529324
IFI35 interferon-induced protein 35 0.00527737
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00527016
ACTN1 actinin, alpha 1 0.00526628
PI3 peptidase inhibitor 3, skin-derived 0.00526052
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00525699
SECTM1 secreted and transmembrane 1 0.00522744
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00522215
DMD dystrophin 0.00520855
CRABP2 cellular retinoic acid binding protein 2 0.00519827
ATP9A ATPase, class II, type 9A 0.00519662
PDHX pyruvate dehydrogenase complex, component X 0.00518966
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 0.00518575
RGS1 regulator of G-protein signaling 1 0.00517074
BAX BCL2-associated X protein 0.00515717
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 0.00514644
KLK8 kallikrein-related peptidase 8 0.00514592
WDR45 WD repeat domain 45 0.00512674
WSB2 WD repeat and SOCS box containing 2 0.00512014
BIK BCL2-interacting killer (apoptosis-inducing) 0.00511373
LYPD1 LY6/PLAUR domain containing 1 0.00508867
LITAF lipopolysaccharide-induced TNF factor 0.00508628
TWF1 twinfilin actin binding protein 1 0.0050756
IGFBP1 insulin-like growth factor binding protein 1 0.00507267
PGAP3 post-GPI attachment to proteins 3 0.00507131
XCL1 chemokine (C motif) ligand 1 0.00506653
LGALS3 lectin, galactoside-binding, soluble, 3 0.00505967
FKBP11 FK506 binding protein 11, 19 kDa 0.00505053
CD58 CD58 molecule 0.00504761
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.00504674
ISG15 ISG15 ubiquitin-like modifier 0.00504279
CCL15 chemokine (C-C motif) ligand 15 0.00503972
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00503373
TNIK TRAF2 and NCK interacting kinase 0.00502661
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 0.00501727
RRAGD Ras-related GTP binding D 0.00499973
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.00499098
VEGFB vascular endothelial growth factor B 0.00498077
IFI6 interferon, alpha-inducible protein 6 0.00497833
LGALS1 lectin, galactoside-binding, soluble, 1 0.0049738
LTBP2 latent transforming growth factor beta binding protein 2 0.00497267
CNN1 calponin 1, basic, smooth muscle 0.00495077
C9ORF91 chromosome 9 open reading frame 91 0.00494961
YBX3 Y box binding protein 3 0.0049414
RCAN1 regulator of calcineurin 1 0.00493727
GAS1 growth arrest-specific 1 0.0049337
AK4 adenylate kinase 4 0.00493157
ORAI3 ORAI calcium release-activated calcium modulator 3 0.00491315
RHOC ras homolog family member C 0.00489083
MREG melanoregulin 0.0048889
BMP4 bone morphogenetic protein 4 0.00488885
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.00488754
KRT23 keratin 23, type I 0.00488534
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00487865
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.00487056
ADAM9 ADAM metallopeptidase domain 9 0.00486851
HSPB1 heat shock 27kDa protein 1 0.00485326
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00484484
TMEM8A transmembrane protein 8A 0.00484193
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.00483778
TULP3 tubby like protein 3 0.00483766
ATF3 activating transcription factor 3 0.00482665
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00481691
LY6E lymphocyte antigen 6 complex, locus E 0.00481549
IRF7 interferon regulatory factor 7 0.00480713
EMP1 epithelial membrane protein 1 0.00479178
BRD4 bromodomain containing 4 0.00479159
IFITM2 interferon induced transmembrane protein 2 0.00478655
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00478571
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.004775
RHOF ras homolog family member F (in filopodia) 0.00477142
JUNB jun B proto-oncogene 0.00477103
KYNU kynureninase 0.00476092
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.00475739
FDXR ferredoxin reductase 0.00475331
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.00475274
EMILIN1 elastin microfibril interfacer 1 0.00474318
EPS8 epidermal growth factor receptor pathway substrate 8 0.0047422
MAPKBP1 mitogen-activated protein kinase binding protein 1 0.00471816
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00471572
NMT2 N-myristoyltransferase 2 0.00471528

decreased expression

Symbol Name Standardized Value
XPO7 exportin 7 -0.0237
MAP7 microtubule-associated protein 7 -0.0184526
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.0124979
TXNDC9 thioredoxin domain containing 9 -0.0115156
AQP1 aquaporin 1 (Colton blood group) -0.0113799
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.0110959
BEX1 brain expressed, X-linked 1 -0.0108838
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0107097
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.0103533
TADA2A transcriptional adaptor 2A -0.0101405
IGFBP5 insulin-like growth factor binding protein 5 -0.00997146
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.0096727
ACTB actin, beta -0.00932131
PBX3 pre-B-cell leukemia homeobox 3 -0.00931331
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00894268
FBP1 fructose-1,6-bisphosphatase 1 -0.00888959
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00865362
WDR7 WD repeat domain 7 -0.00862708
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00855243
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.00833704
SRSF1 serine/arginine-rich splicing factor 1 -0.00788522
ADM adrenomedullin -0.00786479
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00778598
GRK5 G protein-coupled receptor kinase 5 -0.00753969
PRDX2 peroxiredoxin 2 -0.00753474
STEAP3 STEAP family member 3, metalloreductase -0.00751896
RALB v-ral simian leukemia viral oncogene homolog B -0.00749208
CD200 CD200 molecule -0.00749163
HMGB3 high mobility group box 3 -0.00741969
HMGB1 high mobility group box 1 -0.00740302
CALCA calcitonin-related polypeptide alpha -0.00736288
ZBTB18 zinc finger and BTB domain containing 18 -0.00729012
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00728019
ABAT 4-aminobutyrate aminotransferase -0.00727736
TFF3 trefoil factor 3 (intestinal) -0.00727661
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.00727505
TAL1 T-cell acute lymphocytic leukemia 1 -0.00723686
NKX2-1 NK2 homeobox 1 -0.0072344
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00720606
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00716851
MMP12 matrix metallopeptidase 12 -0.00714277
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00713699
UGT8 UDP glycosyltransferase 8 -0.00713055
LMAN1 lectin, mannose-binding, 1 -0.00710128
CDC20 cell division cycle 20 -0.00701034
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00698712
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00697368
ADAM28 ADAM metallopeptidase domain 28 -0.00693376
RIDA reactive intermediate imine deaminase A homolog -0.00691708
INSR insulin receptor -0.00689928
CTSZ cathepsin Z -0.00673849
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -0.0067128
CD1E CD1e molecule -0.00669309
ELANE elastase, neutrophil expressed -0.00667881
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -0.00667427
FZD5 frizzled class receptor 5 -0.00662472
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0065855
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00653342
MMP1 matrix metallopeptidase 1 -0.00651757
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.00648083
TMSB15A thymosin beta 15a -0.00647227
DTX4 deltex 4, E3 ubiquitin ligase -0.00645859
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -0.00643684
ADCY1 adenylate cyclase 1 (brain) -0.00640389
MPO myeloperoxidase -0.00639748
LYZ lysozyme -0.00639019
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00630228
FOCAD focadhesin -0.00629728
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00629501
SIRT3 sirtuin 3 -0.00626996
CA2 carbonic anhydrase II -0.00626732
SCD5 stearoyl-CoA desaturase 5 -0.00624861
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.00623883
IPW imprinted in Prader-Willi syndrome (non-protein coding) -0.00622343
NDFIP1 Nedd4 family interacting protein 1 -0.00622235
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) -0.00620114
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.00619957
RBBP8 retinoblastoma binding protein 8 -0.00619169
ZNF532 zinc finger protein 532 -0.00618293
CDA cytidine deaminase -0.00616317
AZU1 azurocidin 1 -0.00614481
TMEM47 transmembrane protein 47 -0.00612104
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00610951
PTPRE protein tyrosine phosphatase, receptor type, E -0.00609843
DNASE1L3 deoxyribonuclease I-like 3 -0.00609372
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00605452
RGS5 regulator of G-protein signaling 5 -0.0060437
NOX1 NADPH oxidase 1 -0.00604278
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0060344
CD1A CD1a molecule -0.00602709
EXOC5 exocyst complex component 5 -0.00602056
CD1B CD1b molecule -0.00598825
SC5D sterol-C5-desaturase -0.00597248
CRHBP corticotropin releasing hormone binding protein -0.00596245
MYO1D myosin ID -0.00595872
LRP2 low density lipoprotein receptor-related protein 2 -0.00593068
ACAA2 acetyl-CoA acyltransferase 2 -0.00592038
OPHN1 oligophrenin 1 -0.00592014
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.0059119
DPYSL3 dihydropyrimidinase-like 3 -0.00589562
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.00587322
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.00586854
TBX3 T-box 3 -0.00585833
RHOB ras homolog family member B -0.0058512
CPB1 carboxypeptidase B1 (tissue) -0.00584798
TXNL1 thioredoxin-like 1 -0.00584151
MTUS1 microtubule associated tumor suppressor 1 -0.00583836
ESR1 estrogen receptor 1 -0.0058355
COBLL1 cordon-bleu WH2 repeat protein-like 1 -0.00581646
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00580467
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00579641
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -0.00578973
ANPEP alanyl (membrane) aminopeptidase -0.00577345
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -0.00576879
RNASE3 ribonuclease, RNase A family, 3 -0.00575579
EPHX2 epoxide hydrolase 2, cytoplasmic -0.00574183
NEK3 NIMA-related kinase 3 -0.00572997
KRCC1 lysine-rich coiled-coil 1 -0.00572249
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00571128
EREG epiregulin -0.00570501
TUBB2B tubulin, beta 2B class IIb -0.00569785
HSPA13 heat shock protein 70kDa family, member 13 -0.00567351
TFF1 trefoil factor 1 -0.00563054
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00559511
PRTN3 proteinase 3 -0.00558152
TNC tenascin C -0.00557921
CTSG cathepsin G -0.00557504
NAV2 neuron navigator 2 -0.00557139
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00556723
TMCC2 transmembrane and coiled-coil domain family 2 -0.00555952
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00554471
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.0055243
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.0055169
PXDN peroxidasin -0.00551631
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.00551455
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00548093
HHEX hematopoietically expressed homeobox -0.00547507
SNRPA small nuclear ribonucleoprotein polypeptide A -0.00544913
LMNB2 lamin B2 -0.00540618
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00539358
PCLAF PCNA clamp associated factor -0.00537318
ACADL acyl-CoA dehydrogenase, long chain -0.0053637
PAIP2B poly(A) binding protein interacting protein 2B -0.00536245
KCNK5 potassium channel, two pore domain subfamily K, member 5 -0.00535042
LIPG lipase, endothelial -0.00534228
CCN2 cellular communication network factor 2 -0.00534104
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00533421
AFF1 AF4/FMR2 family, member 1 -0.00532676
TMBIM4 transmembrane BAX inhibitor motif containing 4 -0.0053133
RUFY3 RUN and FYVE domain containing 3 -0.00530835
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase -0.00530111
CALR calreticulin -0.00528846
RET ret proto-oncogene -0.00528489
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00527441
EFHD1 EF-hand domain family, member D1 -0.00526637
CLIC2 chloride intracellular channel 2 -0.00523133
PCYOX1 prenylcysteine oxidase 1 -0.00522797
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00522458
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00521587
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00521267
STC1 stanniocalcin 1 -0.00520785
ARMT1 acidic residue methyltransferase 1 -0.00520429
HYOU1 hypoxia up-regulated 1 -0.00519224
ISL1 ISL LIM homeobox 1 -0.00518884
PON3 paraoxonase 3 -0.00518742
UNC13B unc-13 homolog B (C. elegans) -0.005175
EZR ezrin -0.00517217
TTC39A tetratricopeptide repeat domain 39A -0.00516234
ATP10B ATPase, class V, type 10B -0.00515705
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -0.00515661
ABHD17B abhydrolase domain containing 17B -0.00514421
UBA6 ubiquitin-like modifier activating enzyme 6 -0.00513408
CHEK1 checkpoint kinase 1 -0.00512727
CANX calnexin -0.00512689
GSTA1 glutathione S-transferase alpha 1 -0.00512401
SEPP1 selenoprotein P, plasma, 1 -0.0051138
PDZK1 PDZ domain containing 1 -0.00510687
DLAT dihydrolipoamide S-acetyltransferase -0.00508949
ADD2 adducin 2 (beta) -0.00508293
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00508121
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00507838
FLT3 fms-related tyrosine kinase 3 -0.00507797
TG thyroglobulin -0.00506142
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.00504382
SNX7 sorting nexin 7 -0.00504301
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.00501449
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.00500783
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00500699
EML4 echinoderm microtubule associated protein like 4 -0.00500656
SH3YL1 SH3 and SYLF domain containing 1 -0.00498444
INTS9 integrator complex subunit 9 -0.00497704
KIF11 kinesin family member 11 -0.00495994
KDM7A lysine (K)-specific demethylase 7A -0.00495145
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00494877
NPY1R neuropeptide Y receptor Y1 -0.00493656
GPA33 glycoprotein A33 (transmembrane) -0.00491545
NECTIN3 nectin cell adhesion molecule 3 -0.00491284
SCAMP1 secretory carrier membrane protein 1 -0.00490474
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -0.0049031
NPY neuropeptide Y -0.00489549
TSHR thyroid stimulating hormone receptor -0.00489027
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00488556
MMP3 matrix metallopeptidase 3 -0.00487322
DHFR dihydrofolate reductase -0.00487276
DDIT3 DNA-damage-inducible transcript 3 -0.0048684
REV1 REV1, polymerase (DNA directed) -0.00486092
OXA1L oxidase (cytochrome c) assembly 1-like -0.00485356
LEPROTL1 leptin receptor overlapping transcript-like 1 -0.00485262
XBP1 X-box binding protein 1 -0.00484433
UBXN4 UBX domain protein 4 -0.00482228
TUSC3 tumor suppressor candidate 3 -0.00482125
CBX5 chromobox homolog 5 -0.00481113
PNN pinin, desmosome associated protein -0.00481078
TFDP1 transcription factor Dp-1 -0.00481053
MTARC1 mitochondrial amidoxime reducing component 1 -0.00480426
ZC3H13 zinc finger CCCH-type containing 13 -0.00479426
RAB25 RAB25, member RAS oncogene family -0.00478215
CUX2 cut-like homeobox 2 -0.00477376
RTN4 reticulon 4 -0.00476796
SORD sorbitol dehydrogenase -0.00476719
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00476173
CNTNAP2 contactin associated protein-like 2 -0.00475449
MNDA myeloid cell nuclear differentiation antigen -0.00474301
CCL14 chemokine (C-C motif) ligand 14 -0.00474224
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -0.00473076
GTF2I general transcription factor IIi -0.0047282
TLE4 transducin-like enhancer of split 4 -0.00472638
SRSF4 serine/arginine-rich splicing factor 4 -0.004725
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -0.00471733
MLH1 mutL homolog 1 -0.00470579
LIN28A lin-28 homolog A (C. elegans) -0.00470504
GSTM1 glutathione S-transferase mu 1 -0.00470278
CDCA4 cell division cycle associated 4 -0.00469954
MED14 mediator complex subunit 14 -0.00469789
ARMCX2 armadillo repeat containing, X-linked 2 -0.00469198
ELL2 elongation factor, RNA polymerase II, 2 -0.00468606
CHN2 chimerin 2 -0.00467024
MFSD10 major facilitator superfamily domain containing 10 -0.00466734
FRS2 fibroblast growth factor receptor substrate 2 -0.00466651
FGL2 fibrinogen-like 2 -0.00465429
BCLAF1 BCL2-associated transcription factor 1 -0.00465392
KMT2A lysine (K)-specific methyltransferase 2A -0.00464497
NDRG1 N-myc downstream regulated 1 -0.00463814
MTMR9 myotubularin related protein 9 -0.00462573
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00461971
SDC2 syndecan 2 -0.00461374
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) -0.00460882
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -0.00460727
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00460385
PLCB4 phospholipase C, beta 4 -0.00460044