HG-6-64-01 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

97 kinases inhibited by the HG-6-64-01 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
ERBB4 erb-b2 receptor tyrosine kinase 4 1.36211
FGFR1 fibroblast growth factor receptor 1 1.36211
RET ret proto-oncogene 1.36211
TEK TEK tyrosine kinase, endothelial 1.36211
FES FES proto-oncogene, tyrosine kinase 1.35325
LCK LCK proto-oncogene, Src family tyrosine kinase 1.35325
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.35325
FLT4 fms-related tyrosine kinase 4 1.35325
DDR1 discoidin domain receptor tyrosine kinase 1 1.35325
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.35325
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.35325
EPHA8 EPH receptor A8 1.35325
FGR FGR proto-oncogene, Src family tyrosine kinase 1.35325
BLK BLK proto-oncogene, Src family tyrosine kinase 1.35325
STK36 serine/threonine kinase 36 1.34449
BTK Bruton agammaglobulinemia tyrosine kinase 1.34449
EGFR epidermal growth factor receptor 1.33582
RIOK3 RIO kinase 3 1.33582
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1.33582
EPHB1 EPH receptor B1 1.32726
TEC tec protein tyrosine kinase 1.32726
FGFR4 fibroblast growth factor receptor 4 1.32726
TAOK2 TAO kinase 2 1.32726
HCK HCK proto-oncogene, Src family tyrosine kinase 1.32726
SLK STE20-like kinase 1.31878
FRK fyn-related Src family tyrosine kinase 1.31878
MYLK2 myosin light chain kinase 2 1.31878
TXK TXK tyrosine kinase 1.3104
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 1.3104
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.3104
RIOK1 RIO kinase 1 1.30212
TNK2 tyrosine kinase, non-receptor, 2 1.30212
CSK c-src tyrosine kinase 1.30212
PTK2B protein tyrosine kinase 2 beta 1.30212
TAOK1 TAO kinase 1 1.30212
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.30212
SIK1 salt-inducible kinase 1 1.29393
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.29393
STK17B serine/threonine kinase 17b 1.28583
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 1.28583
TNNI3K TNNI3 interacting kinase 1.28583
FLT3 fms-related tyrosine kinase 3 1.28583
FYN FYN proto-oncogene, Src family tyrosine kinase 1.26991
STK17A serine/threonine kinase 17a 1.26209
TNK1 tyrosine kinase, non-receptor, 1 1.25436
MAP3K9 mitogen-activated protein kinase kinase kinase 9 1.25436
MAP3K3 mitogen-activated protein kinase kinase kinase 3 1.25436
AURKC aurora kinase C 1.24671
ULK3 unc-51 like kinase 3 1.24671
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 1.23916
EPHA2 EPH receptor A2 1.2317
SRPK1 SRSF protein kinase 1 1.22432
FGFR3 fibroblast growth factor receptor 3 1.22432
RIPK2 receptor-interacting serine-threonine kinase 2 1.22432
EPHB6 EPH receptor B6 1.22432
EPHA1 EPH receptor A1 1.20983
GAK cyclin G associated kinase 1.19568
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.17508
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha 1.16838
EPHB4 EPH receptor B4 1.16177
MKNK2 MAP kinase interacting serine/threonine kinase 2 1.16177
MINK1 misshapen-like kinase 1 1.15523
LIMK2 LIM domain kinase 2 1.14877
BMP2K BMP2 inducible kinase 1.1424
TNIK TRAF2 and NCK interacting kinase 1.12988
DCLK3 doublecortin-like kinase 3 1.12988
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.11767
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.10576
EPHA5 EPH receptor A5 1.10576
FGFR2 fibroblast growth factor receptor 2 1.09992
CDKL3 cyclin-dependent kinase-like 3 1.08283
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.0718
NEK5 NIMA-related kinase 5 1.06639
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 1.05057
AXL AXL receptor tyrosine kinase 1.05057
EPHB3 EPH receptor B3 1.04543
WEE2 WEE1 homolog 2 (S. pombe) 1.04035
CDK11A cyclin-dependent kinase 11A 1.04035
EPHA3 EPH receptor A3 1.04035
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.02071
STK3 serine/threonine kinase 3 1.02071
HIPK4 homeodomain interacting protein kinase 4 1.00664
ANKK1 ankyrin repeat and kinase domain containing 1 0.997567
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.997567
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.984392
BMX BMX non-receptor tyrosine kinase 0.959553
TTK TTK protein kinase 0.9517
SYK spleen tyrosine kinase 0.936602
LIMK1 LIM domain kinase 1 0.918808
STK11 serine/threonine kinase 11 0.91201
GRK4 G protein-coupled receptor kinase 4 0.902136
NEK9 NIMA-related kinase 9 0.895762
CDK11B cyclin-dependent kinase 11B 0.892635
ULK1 unc-51 like autophagy activating kinase 1 0.892635
DDR2 discoidin domain receptor tyrosine kinase 2 0.877587
MERTK MER proto-oncogene, tyrosine kinase 0.871827
PTK6 protein tyrosine kinase 6 0.860727